MGI MP annotations for MGI:109334: Irs2

Gray arrows indicate "is_a"



Compare annotations to MP categories for MGI:109334.

• Entry indicates phenotypic allele for this gene.
• Colored entries indicate MP annotation.

ID	Term	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0005375	adipose tissue phenotype	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0005386	behavior/neurological phenotype	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0005385	cardiovascular system phenotype	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0005384	cellular phenotype	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0005379	endocrine/exocrine gland phenotype	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0005378	growth/size phenotype	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0005376	homeostasis/metabolism phenotype	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0010768	mortality/aging	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0005369	muscle phenotype	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0003631	nervous system phenotype	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0005367	renal/urinary system phenotype	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka
MP:0005389	reproductive system phenotype	Irs2tm1.1With	Irs2tm1Mfw	Irs2tm1Tka

Full set of annotations for MGI:109334

ID	Term	Allele	Alleles	Background	Color Key
MP:0005076	abnormal cell differentiation	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0000188	abnormal circulating glucose level	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001560	abnormal circulating insulin level	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	Not Specified	color key
MP:0002679	abnormal corpus luteum morphology	Irs2tm1.1With	Irs2tm1.1With/Irs2tm1.1With	B6.129S6-Irs2	color key
MP:0005448	abnormal energy balance	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0002078	abnormal glucose homeostasis	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0002118	abnormal lipid homeostasis	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6J	color key
MP:0001377	abnormal mating frequency	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001931	abnormal oogenesis	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001131	abnormal ovarian follicle morphology	Irs2tm1.1With	Irs2tm1.1With/Irs2tm1.1With	B6.129S6-Irs2	color key
MP:0001131	abnormal ovarian follicle morphology	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001130	abnormal ovarian folliculogenesis	Irs2tm1.1With	Irs2tm1.1With/Irs2tm1.1With	B6.129S6-Irs2	color key
MP:0001928	abnormal ovulation	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0005217	abnormal pancreatic beta cell morphology	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6J	color key
MP:0005217	abnormal pancreatic beta cell morphology	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0004883	abnormal vascular wound healing	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0001134	absent corpus luteum	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0009009	absent estrous cycle	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0008869	anovulation	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001265	decreased body size	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0001262	decreased body weight	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001262	decreased body weight	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0005181	decreased circulating estradiol level	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0002773	decreased circulating luteinizing hormone level	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0005185	decreased circulating progesterone level	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0005121	decreased circulating prolactin level	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0002780	decreased circulating testosterone level	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0005439	decreased glycogen level	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0008335	decreased gonadotroph cell number	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0005431	decreased oocyte number	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0009114	decreased pancreatic beta cell mass	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129 * C57BL/6J	color key
MP:0009114	decreased pancreatic beta cell mass	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0009114	decreased pancreatic beta cell mass	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0003339	decreased pancreatic beta cell number	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	Not Specified	color key
MP:0005591	decreased vasodilation	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0001926	female infertility	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001559	hyperglycemia	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129 * C57BL/6J	color key
MP:0001559	hyperglycemia	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6J	color key
MP:0001559	hyperglycemia	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0001559	hyperglycemia	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	Not Specified	color key
MP:0001559	hyperglycemia	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0005293	impaired glucose tolerance	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0005293	impaired glucose tolerance	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0005293	impaired glucose tolerance	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0001129	impaired ovarian folliculogenesis	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001556	increased circulating HDL cholesterol level	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0005178	increased circulating cholesterol level	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0001554	increased circulating free fatty acid level	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0002079	increased circulating insulin level	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129 * C57BL/6J	color key
MP:0002079	increased circulating insulin level	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0002079	increased circulating insulin level	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0005669	increased circulating leptin level	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001552	increased circulating triglyceride level	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0003058	increased insulin secretion	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0006144	increased systemic arterial systolic blood pressure	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0010024	increased total body fat amount	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0005331	insulin resistance	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129 * C57BL/6J	color key
MP:0005331	insulin resistance	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0005331	insulin resistance	Irs2tm1Tka	Irs2tm1Tka/Irs2tm1Tka	involves: C57BL/6 * CBA	color key
MP:0001261	obese	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001426	polydipsia	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0009433	polyovular ovarian follicle	Irs2tm1.1With	Irs2tm1.1With/Irs2tm1.1With	B6.129S6-Irs2	color key
MP:0001433	polyphagia	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001762	polyuria	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0002083	premature death	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	color key
MP:0002083	premature death	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	Not Specified	color key
MP:0001923	reduced female fertility	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001922	reduced male fertility	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001127	small ovary	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0009172	small pancreatic islets	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6J	color key
MP:0005361	small pituitary gland	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0008368	small pituitary intermediate lobe	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129/Sv * C57BL/6	color key
MP:0001263	weight loss	Irs2tm1Mfw	Irs2tm1Mfw/Irs2tm1Mfw	involves: 129 * C57BL/6J	color key