MGI MP annotations for MGI:1354161: Sirt6

Gray arrows indicate "is_a"



Compare annotations to MP categories for MGI:1354161.

• Entry indicates phenotypic allele for this gene.
• Colored entries indicate MP annotation.

ID	Term	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005375	adipose tissue phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005386	behavior/neurological phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005384	cellular phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005382	craniofacial phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005381	digestive/alimentary phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005378	growth/size phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005397	hematopoietic system phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005376	homeostasis/metabolism phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005387	immune system phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0010771	integument phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0010768	mortality/aging	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005389	reproductive system phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005390	skeleton phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd
MP:0005391	vision/eye phenotype	Sirt6tm1Fwa	Sirt6tm2.1Cxd	Sirt6tm2.2Cxd

Full set of annotations for MGI:1354161

ID	Term	Allele	Alleles	Background	Color Key
MP:0002144	abnormal B cell differentiation	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0002092	abnormal eye morphology	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0002092	abnormal eye morphology	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0002078	abnormal glucose homeostasis	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0002078	abnormal glucose homeostasis	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0002401	abnormal lymphopoiesis	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0001382	abnormal nursing	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0001382	abnormal nursing	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0008737	abnormal spleen physiology	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0008737	abnormal spleen physiology	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0002816	colitis	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0011083	complete lethality at weaning	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0001265	decreased body size	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0001265	decreased body size	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0001265	decreased body size	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0001262	decreased body weight	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0001262	decreased body weight	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0000333	decreased bone marrow cell number	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0000063	decreased bone mineral density	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0000063	decreased bone mineral density	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0000063	decreased bone mineral density	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0000352	decreased cell proliferation	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0005560	decreased circulating glucose level	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0005560	decreased circulating glucose level	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0005560	decreased circulating glucose level	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0002727	decreased circulating insulin level	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0002727	decreased circulating insulin level	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0004701	decreased circulating insulin-like growth factor I level	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0005092	decreased double-positive T cell number	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0000221	decreased leukocyte cell number	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0008844	decreased subcutaneous adipose tissue amount	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0008844	decreased subcutaneous adipose tissue amount	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0008844	decreased subcutaneous adipose tissue amount	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0010025	decreased total body fat amount	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0010025	decreased total body fat amount	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0008008	early cellular replicative senescence	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0008008	early cellular replicative senescence	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0000189	hypoglycemia	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0000189	hypoglycemia	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0008402	increased cellular sensitivity to alkylating agents	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0004227	increased cellular sensitivity to ionizing radiation	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0002891	increased insulin sensitivity	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0002891	increased insulin sensitivity	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0000160	kyphosis	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0000160	kyphosis	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0000160	kyphosis	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0000162	lordosis	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0000162	lordosis	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0000162	lordosis	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0001925	male infertility	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0001925	male infertility	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0000120	malocclusion	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0000120	malocclusion	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0005287	narrow eye opening	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0005287	narrow eye opening	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0001732	postnatal growth retardation	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0003786	premature aging	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0003786	premature aging	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0002083	premature death	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0002083	premature death	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0001923	reduced female fertility	Sirt6tm2.1Cxd	Sirt6tm2.1Cxd/Sirt6tm2.1Cxd	involves: 129S6/SvEvTac * NIH Black Swiss	color key
MP:0001923	reduced female fertility	Sirt6tm2.2Cxd	Sirt6tm2.2Cxd/Sirt6tm2.2Cxd	involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss	color key
MP:0000694	spleen hypoplasia	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key
MP:0004029	spontaneous chromosome breakage	Sirt6tm1Fwa	Sirt6tm1Fwa/Sirt6tm1Fwa	involves: 129X1/SvJ	color key