MGI MP annotations for MGI:2135607

MGI MP annotations for MGI:2135607: Sirt1

Gray arrows indicate "is_a"

Compare annotations to MP categories for MGI:2135607.

Entry indicates phenotypic allele for this gene.
Colored entries indicate MP annotation.

ID	Term	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005375	adipose tissue phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005386	behavior/neurological phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005385	cardiovascular system phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005384	cellular phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005382	craniofacial phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005381	digestive/alimentary phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005380	embryogenesis phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005379	endocrine/exocrine gland phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005378	growth/size phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005397	hematopoietic system phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005376	homeostasis/metabolism phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005387	immune system phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0010771	integument phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005371	limbs/digits/tail phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0010768	mortality/aging	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0003631	nervous system phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0002873	normal phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005367	renal/urinary system phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005389	reproductive system phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005388	respiratory system phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa
MP:0005391	vision/eye phenotype	Sirt1^tm1.1Cxd	Sirt1^tm1.1Ygu	Sirt1^tm1Fwa	Sirt1^tm1Mcby	Sirt1^tm1Ygu	Sirt1^tm2.1Fwa	Sirt1^tm2.1Mcby	Sirt1^tm2Fwa

Full set of annotations for MGI:2135607

ID	Term	Allele	Alleles	Background	Color Key
MP:0005536	Leydig cell hypoplasia	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0008058	abnormal DNA repair	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0008057	abnormal DNA replication	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0002786	abnormal Leydig cell morphology	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0004109	abnormal Sertoli cell development	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0002745	abnormal atrioventricular valve morphology	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0000662	abnormal branching of the mammary ductal tree	Sirt1^tm1.1Ygu	Sirt1^tm1.1Ygu/Sirt1^tm1.1Ygu	involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6	color key
MP:0004045	abnormal cell cycle checkpoint function	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0000313	abnormal cell death	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0010954	abnormal cellular respiration	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0003702	abnormal chromosome morphology	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0006280	abnormal digit development	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0006280	abnormal digit development	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0005450	abnormal energy expenditure	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001927	abnormal estrous cycle	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001286	abnormal eye development	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0002092	abnormal eye morphology	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0002092	abnormal eye morphology	Sirt1^tm2.1Fwa	Sirt1^tm2.1Fwa/Sirt1^tm2.1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0002092	abnormal eye morphology	Sirt1^tm2Fwa	Sirt1^tm2Fwa/Sirt1^tm2Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0002078	abnormal glucose homeostasis	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0005291	abnormal glucose tolerance	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0005291	abnormal glucose tolerance	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0000432	abnormal head morphology	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0000267	abnormal heart development	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0005336	abnormal inguinal fat pad morphology	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001882	abnormal lactation	Sirt1^tm1.1Ygu	Sirt1^tm1.1Ygu/Sirt1^tm1.1Ygu	involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6	color key
MP:0006269	abnormal mammary gland growth during pregnancy	Sirt1^tm1.1Ygu	Sirt1^tm1.1Ygu/Sirt1^tm1.1Ygu	involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6	color key
MP:0000627	abnormal mammary gland morphology	Sirt1^tm1.1Ygu	Sirt1^tm1.1Ygu/Sirt1^tm1.1Ygu	involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6	color key
MP:0001382	abnormal nursing	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0005325	abnormal renal glomerulus morphology	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0003727	abnormal retinal layer morphology	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0001004	abnormal retinal photoreceptor morphology	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0006304	abnormal seminiferous epithelium morphology	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002216	abnormal seminiferous tubule morphology	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0008892	abnormal sperm flagellum morphology	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0006380	abnormal spermatid morphology	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0006380	abnormal spermatid morphology	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0006379	abnormal spermatocyte morphology	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0001156	abnormal spermatogenesis	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002782	abnormal testes secretion	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0004902	abnormal uterus size	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001134	absent corpus luteum	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0009009	absent estrous cycle	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0004573	absent limb buds	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0004024	aneuploidy	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0008869	anovulation	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0008261	arrest of male meiosis	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0001155	arrest of spermatogenesis	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0002675	asthenozoospermia	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002675	asthenozoospermia	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0010403	atrial septal defect	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0010403	atrial septal defect	Sirt1^tm2Fwa	Sirt1^tm2Fwa/Sirt1^tm2Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0011085	complete postnatal lethality	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0008079	decreased CD8-positive T cell number	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0008079	decreased CD8-positive T cell number	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001265	decreased body size	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0001265	decreased body size	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0001265	decreased body size	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0001265	decreased body size	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001262	decreased body weight	Sirt1^tm1.1Ygu	Sirt1^tm1.1Ygu/Sirt1^tm1.1Ygu	involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6	color key
MP:0001262	decreased body weight	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0001262	decreased body weight	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0001262	decreased body weight	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002175	decreased brain weight	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002790	decreased circulating follicle stimulating hormone level	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0002727	decreased circulating insulin level	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002773	decreased circulating luteinizing hormone level	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0005478	decreased circulating thyroxine level	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001698	decreased embryo size	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0001698	decreased embryo size	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0001698	decreased embryo size	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0001698	decreased embryo size	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0010379	decreased respiratory quotient	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0008770	decreased survivor rate	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0004852	decreased testis weight	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002988	decreased urine osmolality	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001783	decreased white adipose tissue amount	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0008512	disorganized retinal inner nuclear layer	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0008516	disorganized retinal outer nuclear layer	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0000274	enlarged heart	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0003450	enlarged pancreas	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0000691	enlarged spleen	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0000914	exencephaly	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0009164	exocrine pancreas atrophy	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0009164	exocrine pancreas atrophy	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0005176	eyelids fail to open	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0005176	eyelids fail to open	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0005176	eyelids fail to open	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001926	female infertility	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0002686	globozoospermia	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002743	glomerulonephritis	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0000276	heart right ventricle hypertrophy	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0000276	heart right ventricle hypertrophy	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001402	hypoactivity	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0004794	increased anti-nuclear antigen antibody level	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0005238	increased brain size	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002007	increased cellular sensitivity to gamma-irradiation	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0004227	increased cellular sensitivity to ionizing radiation	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0008410	increased cellular sensitivity to ultraviolet irradiation	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0003909	increased eating behavior	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002461	increased immunoglobulin level	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0003058	increased insulin secretion	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0004760	increased mitotic index	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0005289	increased oxygen consumption	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0005289	increased oxygen consumption	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0011543	increased urine antidiuretic hormone level	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001862	interstitial pneumonia	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0001862	interstitial pneumonia	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001861	lung inflammation	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0001861	lung inflammation	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0008280	male germ cell apoptosis	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0008280	male germ cell apoptosis	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001925	male infertility	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0001925	male infertility	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0001925	male infertility	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001925	male infertility	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001297	microphthalmia	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0001297	microphthalmia	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0001297	microphthalmia	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002169	no abnormal phenotype detected	Sirt1^tm1Ygu	Sirt1^tm1Ygu/Sirt1^tm1Ygu	involves: 129/Sv * C57BL/6	color key
MP:0002687	oligozoospermia	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0002687	oligozoospermia	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0002687	oligozoospermia	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0011108	partial embryonic lethality during organogenesis	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0011109	partial lethality throughout fetal growth and development	Sirt1^tm1.1Cxd	Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd	either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)	color key
MP:0011088	partial neonatal lethality	Sirt1^tm1.1Ygu	Sirt1^tm1.1Ygu/Sirt1^tm1.1Ygu	involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6	color key
MP:0011090	partial perinatal lethality	Sirt1^tm1.1Ygu	Sirt1^tm1.1Ygu/Sirt1^tm1.1Ygu	involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6	color key
MP:0011090	partial perinatal lethality	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0011090	partial perinatal lethality	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0011090	partial perinatal lethality	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0011086	partial postnatal lethality	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key
MP:0011086	partial postnatal lethality	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ	color key
MP:0011086	partial postnatal lethality	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001426	polydipsia	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001433	polyphagia	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001732	postnatal growth retardation	Sirt1^tm1.1Ygu	Sirt1^tm1.1Ygu/Sirt1^tm1.1Ygu	involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6	color key
MP:0001732	postnatal growth retardation	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0002082	postnatal lethality	Sirt1^tm1.1Ygu	Sirt1^tm1.1Ygu/Sirt1^tm1.1Ygu	involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6	color key
MP:0002083	premature death	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0003828	pulmonary edema	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0003828	pulmonary edema	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001923	reduced female fertility	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0000445	short snout	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129	color key
MP:0000445	short snout	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0000445	short snout	Sirt1^tm2.1Mcby	Sirt1^tm2.1Mcby/Sirt1^tm2.1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0008489	slow postnatal weight gain	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001127	small ovary	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0001153	small seminiferous tubules	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	129/Sv-Sirt1	color key
MP:0005578	teratozoospermia	Sirt1^tm1Mcby	Sirt1^tm1Mcby/Sirt1^tm1Mcby	involves: 129S1/Sv * 129X1/SvJ * CD-1	color key
MP:0010402	ventricular septal defect	Sirt1^tm1Fwa	Sirt1^tm1Fwa/Sirt1^tm1Fwa	involves: 129/Sv * 129S6/SvEvTac	color key