Compare GO annotations for HomoloGene:1171 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0003677	DNA binding	MGI:106918	Hif1a	IDA	Mouse	MGI:MGI:3056854\|PMID:15456877
Molecular Function	GO:0003677	DNA binding	MGI:106918	Hif1a	IGI	Mouse	MGI:MGI:894004\|PMID:9113979
Molecular Function	GO:0003677	DNA binding	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Molecular Function	GO:0035035	histone acetyltransferase binding	Q16665	HIF1A_HUMAN	IPI	Human	PMID:15261140
Molecular Function	GO:0035035	histone acetyltransferase binding	RGD:61928	Hif1a	ISS	Rat	RGD:1580655
Molecular Function	GO:0035035	histone acetyltransferase binding	RGD:61928	Hif1a	ISS	Rat	RGD:1600115
Molecular Function	GO:0035035	histone acetyltransferase binding	Q9YIB9	HIF1A_CHICK	ISS	Chicken	UniProt:Q9YIB9
Molecular Function	GO:0005515	protein binding	Q16665	HIF1A_HUMAN	IPI	Human	PMID:9887100
Molecular Function	GO:0005515	protein binding	MGI:106918	Hif1a	IPI	Mouse	MGI:MGI:2176655\|PMID:11782478
Molecular Function	GO:0005515	protein binding	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	RGD:61928	Hif1a	ISS	Rat	RGD:1580655
Molecular Function	GO:0005515	protein binding	RGD:61928	Hif1a	ISS	Rat	RGD:1600115
Molecular Function	GO:0005515	protein binding	Q9YIB9	HIF1A_CHICK	ISS	Chicken	UniProt:Q9YIB9
Molecular Function	GO:0046982	protein heterodimerization activity	Q16665	HIF1A_HUMAN	IPI	Human	PMID:12239177
Molecular Function	GO:0046982	protein heterodimerization activity	RGD:61928	Hif1a	ISS	Rat	RGD:1580655
Molecular Function	GO:0046982	protein heterodimerization activity	RGD:61928	Hif1a	ISS	Rat	RGD:1600115
Molecular Function	GO:0046982	protein heterodimerization activity	Q9YIB9	HIF1A_CHICK	ISS	Chicken	UniProt:Q9YIB9
Molecular Function	GO:0003705	RNA polymerase II transcription factor activity, enhancer binding	RGD:61928	Hif1a	ISS	Rat	RGD:1580655
Molecular Function	GO:0043565	sequence-specific DNA binding	RGD:61928	Hif1a	IDA	Rat	RGD:632652\|PMID:12675925
Molecular Function	GO:0003704	specific RNA polymerase II transcription factor activity	RGD:61928	Hif1a	IDA	Rat	RGD:68201\|PMID:11237857
Molecular Function	GO:0003700	transcription factor activity	MGI:106918	Hif1a	IDA	Mouse	MGI:MGI:3056854\|PMID:15456877
Molecular Function	GO:0003700	transcription factor activity	MGI:106918	Hif1a	ISS	Mouse	MGI:MGI:2176655\|PMID:11782478
Molecular Function	GO:0003700	transcription factor activity	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Cellular Component	GO:0005737	cytoplasm	RGD:61928	Hif1a	IDA	Rat	RGD:68201\|PMID:11237857
Cellular Component	GO:0009434	microtubule-based flagellum	MGI:106918	Hif1a	IDA	Mouse	MGI:MGI:2158034\|PMID:11818497
Cellular Component	GO:0009434	microtubule-based flagellum	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Cellular Component	GO:0005634	nucleus	Q16665	HIF1A_HUMAN	IDA	Human	PMID:15261140
Cellular Component	GO:0005634	nucleus	MGI:106918	Hif1a	IDA	Mouse	MGI:MGI:3045517\|PMID:15016652
Cellular Component	GO:0005634	nucleus	MGI:106918	Hif1a	IDA	Mouse	MGI:MGI:3056854\|PMID:15456877
Cellular Component	GO:0005634	nucleus	MGI:106918	Hif1a	IDA	Mouse	MGI:MGI:2153426\|PMID:11691837
Cellular Component	GO:0005634	nucleus	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Cellular Component	GO:0005634	nucleus	RGD:61928	Hif1a	ISS	Rat	RGD:1580655
Cellular Component	GO:0005634	nucleus	RGD:61928	Hif1a	IDA	Rat	RGD:1581932\|PMID:11313887
Cellular Component	GO:0005634	nucleus	RGD:61928	Hif1a	ISS	Rat	RGD:1600115
Cellular Component	GO:0005634	nucleus	Q9YIB9	HIF1A_CHICK	ISS	Chicken	UniProt:Q9YIB9
Cellular Component	GO:0005667	transcription factor complex	MGI:106918	Hif1a	ISS	Mouse	MGI:MGI:2154458
Biological Process	GO:0001525	angiogenesis	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3039988\|PMID:15073147
Biological Process	GO:0001525	angiogenesis	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3607736\|PMID:14659802
Biological Process	GO:0001525	angiogenesis	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Biological Process	GO:0051216	cartilage development	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:2153426\|PMID:11691837
Biological Process	GO:0030154	cell differentiation	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3039988\|PMID:15073147
Biological Process	GO:0030154	cell differentiation	MGI:106918	Hif1a	IGI	Mouse	MGI:MGI:3703383\|PMID:16287860
Biological Process	GO:0030154	cell differentiation	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Biological Process	GO:0006879	cellular iron ion homeostasis	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3695187\|PMID:16787915
Biological Process	GO:0035162	embryonic hemopoiesis	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3695187\|PMID:16787915
Biological Process	GO:0001892	embryonic placenta development	MGI:106918	Hif1a	IGI	Mouse	MGI:MGI:3703383\|PMID:16287860
Biological Process	GO:0001892	embryonic placenta development	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3703383\|PMID:16287860
Biological Process	GO:0001947	heart looping	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3607736\|PMID:14659802
Biological Process	GO:0001947	heart looping	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Biological Process	GO:0042541	hemoglobin biosynthetic process	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3695187\|PMID:16787915
Biological Process	GO:0042592	homeostatic process	RGD:61928	Hif1a	ISS	Rat	RGD:1580655
Biological Process	GO:0045926	negative regulation of growth	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:2153426\|PMID:11691837
Biological Process	GO:0001755	neural crest cell migration	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3607736\|PMID:14659802
Biological Process	GO:0001755	neural crest cell migration	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3695187\|PMID:16787915
Biological Process	GO:0045941	positive regulation of transcription	Q16665	HIF1A_HUMAN	IDA	Human	PMID:9887100
Biological Process	GO:0045941	positive regulation of transcription	RGD:61928	Hif1a	ISS	Rat	RGD:1600115
Biological Process	GO:0045941	positive regulation of transcription	Q9YIB9	HIF1A_CHICK	ISS	Chicken	UniProt:Q9YIB9
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:106918	Hif1a	IGI	Mouse	MGI:MGI:3577779\|PMID:15766748
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:106918	Hif1a	IGI	Mouse	MGI:MGI:894004\|PMID:9113979
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3703197\|PMID:17284606
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:106918	Hif1a	ISS	Mouse	MGI:MGI:2154458
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	RGD:61928	Hif1a	IDA	Rat	RGD:68201\|PMID:11237857
Biological Process	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:2153426\|PMID:11691837
Biological Process	GO:0042981	regulation of apoptosis	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:3056854\|PMID:15456877
Biological Process	GO:0042981	regulation of apoptosis	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Biological Process	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	MGI:106918	Hif1a	IMP	Mouse	MGI:MGI:2667513\|PMID:12832481
Biological Process	GO:0006355	regulation of transcription, DNA-dependent	Q16665	HIF1A_HUMAN	IDA	Human	PMID:11782478
Biological Process	GO:0006355	regulation of transcription, DNA-dependent	MGI:106918	Hif1a	IDA	Mouse	MGI:MGI:3056854\|PMID:15456877
Biological Process	GO:0006355	regulation of transcription, DNA-dependent	MGI:106918	Hif1a	ISS	Mouse	MGI:MGI:2176655\|PMID:11782478
Biological Process	GO:0006355	regulation of transcription, DNA-dependent	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Biological Process	GO:0006355	regulation of transcription, DNA-dependent	RGD:61928	Hif1a	ISS	Rat	RGD:1580655
Biological Process	GO:0001666	response to hypoxia	Q16665	HIF1A_HUMAN	IDA	Human	PMID:9887100
Biological Process	GO:0001666	response to hypoxia	Q16665	HIF1A_HUMAN	IDA	Human	PMID:15261140
Biological Process	GO:0001666	response to hypoxia	MGI:106918	Hif1a	IDA	Mouse	MGI:MGI:2158032\|PMID:11801735
Biological Process	GO:0001666	response to hypoxia	MGI:106918	Hif1a	ISS	Mouse	MGI:MGI:2176655\|PMID:11782478
Biological Process	GO:0001666	response to hypoxia	RGD:61928	Hif1a	IDA	Rat	RGD:628389\|PMID:12388599
Biological Process	GO:0001666	response to hypoxia	RGD:61928	Hif1a	ISS	Rat	RGD:1580654
Biological Process	GO:0001666	response to hypoxia	RGD:61928	Hif1a	ISS	Rat	RGD:1580655
Biological Process	GO:0001666	response to hypoxia	RGD:61928	Hif1a	IDA	Rat	RGD:632652\|PMID:12675925
Biological Process	GO:0001666	response to hypoxia	RGD:61928	Hif1a	ISS	Rat	RGD:1600115
Biological Process	GO:0001666	response to hypoxia	Q9YIB9	HIF1A_CHICK	ISS	Chicken	UniProt:Q9YIB9
Biological Process	GO:0007165	signal transduction	RGD:61928	Hif1a	ISS	Rat	RGD:1580655

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)