Category | ID | Term | DB Object | DB Symbol | Evidence | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0004175 | endopeptidase activity | FBgn0053198 | pen-2 | IDA | Fly | FB:FBrf0157158|PMID:12660785 |
Molecular Function | GO:0005515 | protein binding | Q9NZ42 | PEN2_HUMAN | IPI | Human | PMID:16641999 |
Molecular Function | GO:0005515 | protein binding | MGI:1913590 | Psenen | IPI | Mouse | MGI:MGI:3623864|PMID:16641999 |
Cellular Component | GO:0005783 | endoplasmic reticulum | Q9NZ42 | PEN2_HUMAN | IDA | Human | PMID:15274632 |
Cellular Component | GO:0005794 | Golgi apparatus | Q9NZ42 | PEN2_HUMAN | IDA | Human | PMID:15274632 |
Cellular Component | GO:0005887 | integral to plasma membrane | Q9NZ42 | PEN2_HUMAN | IDA | Human | PMID:15274632 |
Biological Process | GO:0006509 | membrane protein ectodomain proteolysis | Q9NZ42 | PEN2_HUMAN | IDA | Human | PMID:15274632 |
Biological Process | GO:0043066 | negative regulation of apoptosis | ZDB-GENE-040218-1 | psenen | IMP | Zfin | ZFIN:ZDB-PUB-060313-9|PMID:16507571 |
Biological Process | GO:0043524 | negative regulation of neuron apoptosis | ZDB-GENE-040218-1 | psenen | IMP | Zfin | ZFIN:ZDB-PUB-060210-19|PMID:16464238 |
Biological Process | GO:0043085 | positive regulation of enzyme activity | Q9NZ42 | PEN2_HUMAN | IDA | Human | PMID:15274632 |
Biological Process | GO:0016485 | protein processing | Q9NZ42 | PEN2_HUMAN | IDA | Human | PMID:15274632 |
IC Inferred by curator |
IDA Inferred from direct assay |
IEA Inferred from electronic annotation |
IEP Inferred from expression pattern |
IGC Inferred from genomic context |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
ISS Inferred from sequence or structural similarity |
NAS Non-traceable Author Statement |
ND No biological data available |
RCA Reviewed computational analysis |
TAS Traceable author statement |
NR Not recorded (appears in some legacy annotations) |