Compare GO annotations for HomoloGene:1257 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0003924	GTPase activity	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:2447568\|PMID:10699171
Molecular Function	GO:0003924	GTPase activity	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:3050945\|PMID:15249579
Molecular Function	GO:0003924	GTPase activity	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:3575983\|PMID:15798203
Molecular Function	GO:0003924	GTPase activity	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	P61586	RHOA_HUMAN	IPI	Human	PMID:15644318
Molecular Function	GO:0005515	protein binding	MGI:1096342	Rhoa	IPI	Mouse	MGI:MGI:77862\|PMID:8543060
Molecular Function	GO:0005515	protein binding	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Molecular Function	GO:0004871	signal transducer activity	P61586	RHOA_HUMAN	IEP	Human	PMID:12761501
Molecular Function	GO:0004871	signal transducer activity	RGD:619921	Rhoa	ISS	Rat	RGD:1600115
Molecular Function	GO:0004871	signal transducer activity	O93467	O93467_CHICK	ISS	Chicken	UniProt:O93467
Cellular Component	GO:0005829	cytosol	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:2175934\|PMID:11877460
Cellular Component	GO:0005829	cytosol	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Cellular Component	GO:0005634	nucleus	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:3039970\|PMID:15093731
Cellular Component	GO:0005634	nucleus	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Cellular Component	GO:0005886	plasma membrane	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:3039970\|PMID:15093731
Cellular Component	GO:0005886	plasma membrane	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Biological Process	GO:0030036	actin cytoskeleton organization and biogenesis	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:3028433\|PMID:1643657
Biological Process	GO:0030036	actin cytoskeleton organization and biogenesis	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Biological Process	GO:0007155	cell adhesion	MGI:1096342	Rhoa	IMP	Mouse	MGI:MGI:3028451\|PMID:14657280
Biological Process	GO:0007155	cell adhesion	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Biological Process	GO:0030154	cell differentiation	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:2175934\|PMID:11877460
Biological Process	GO:0030154	cell differentiation	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Biological Process	GO:0000902	cell morphogenesis	MGI:1096342	Rhoa	IGI	Mouse	MGI:MGI:3576987\|PMID:15860730
Biological Process	GO:0007160	cell-matrix adhesion	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:3028433\|PMID:1643657
Biological Process	GO:0007160	cell-matrix adhesion	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Biological Process	GO:0007229	integrin-mediated signaling pathway	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Biological Process	GO:0043524	negative regulation of neuron apoptosis	MGI:1096342	Rhoa	IMP	Mouse	MGI:MGI:3588743\|PMID:15071095
Biological Process	GO:0043524	negative regulation of neuron apoptosis	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Biological Process	GO:0045665	negative regulation of neuron differentiation	RGD:619921	Rhoa	IMP	Rat	RGD:1299270\|PMID:14517206
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	P61586	RHOA_HUMAN	IEP	Human	PMID:12761501
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	RGD:619921	Rhoa	ISS	Rat	RGD:1600115
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	O93467	O93467_CHICK	ISS	Chicken	UniProt:O93467
Biological Process	GO:0007266	Rho protein signal transduction	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Biological Process	GO:0043149	stress fiber formation	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:3027647\|PMID:14614988
Biological Process	GO:0043149	stress fiber formation	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:2447568\|PMID:10699171
Biological Process	GO:0043149	stress fiber formation	RGD:619921	Rhoa	ISS	Rat	RGD:1580654
Biological Process	GO:0007519	striated muscle development	MGI:1096342	Rhoa	IDA	Mouse	MGI:MGI:2175934\|PMID:11877460
Biological Process	GO:0007519	striated muscle development	RGD:619921	Rhoa	ISS	Rat	RGD:1580654

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)