Compare GO annotations for HomoloGene:139 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3611729\|PMID:16396903
Molecular Function	GO:0003677	DNA binding	ZDB-GENE-041111-162	gli3	ISS	Zfin	ZFIN:ZDB-PUB-041228-22\|PMID:15617692
Molecular Function	GO:0005515	protein binding	P10071	GLI3_HUMAN	IPI	Human	PMID:11238441
Molecular Function	GO:0005515	protein binding	P10071	GLI3_HUMAN	IPI	Human	PMID:10564661
Molecular Function	GO:0005515	protein binding	P10071	GLI3_HUMAN	IPI	Human	PMID:10806483
Molecular Function	GO:0005515	protein binding	MGI:95729	Gli3	IPI	Mouse	MGI:MGI:2445270\|PMID:12435627
Molecular Function	GO:0043565	sequence-specific DNA binding	MGI:95729	Gli3	IDA	Mouse	MGI:MGI:3624046\|PMID:16611981
Cellular Component	GO:0005737	cytoplasm	MGI:95729	Gli3	IDA	Mouse	MGI:MGI:2445270\|PMID:12435627
Cellular Component	GO:0005737	cytoplasm	FBgn0004859	ci	IDA	Fly	FB:FBrf0090554\|PMID:8898240
Cellular Component	GO:0005737	cytoplasm	FBgn0004859	ci	IDA	Fly	FB:FBrf0128675\|PMID:10862750
Cellular Component	GO:0005737	cytoplasm	FBgn0004859	ci	IDA	Fly	FB:FBrf0190106\|PMID:16413529
Cellular Component	GO:0035301	Hedgehog signaling complex	FBgn0004859	ci	IPI	Fly	FB:FBrf0128807\|PMID:10825151
Cellular Component	GO:0016020	membrane	FBgn0004859	ci	IDA	Fly	FB:FBrf0174792\|PMID:14645371
Cellular Component	GO:0005634	nucleus	MGI:95729	Gli3	IDA	Mouse	MGI:MGI:2445270\|PMID:12435627
Cellular Component	GO:0005634	nucleus	FBgn0004859	ci	IDA	Fly	FB:FBrf0128675\|PMID:10862750
Cellular Component	GO:0005634	nucleus	FBgn0004859	ci	IDA	Fly	FB:FBrf0190106\|PMID:16413529
Cellular Component	GO:0017053	transcriptional repressor complex	MGI:95729	Gli3	IDA	Mouse	MGI:MGI:2445270\|PMID:12435627
Biological Process	GO:0048856	anatomical structure development	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:2148409\|PMID:11485934
Biological Process	GO:0048646	anatomical structure formation	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:1277743\|PMID:9731531
Biological Process	GO:0009952	anterior/posterior pattern formation	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:3053244\|PMID:15315762
Biological Process	GO:0007420	brain development	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:2445242\|PMID:12435361
Biological Process	GO:0048754	branching morphogenesis of a tube	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:3608164\|PMID:16247775
Biological Process	GO:0048593	camera-type eye morphogenesis	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:52587\|PMID:8387379
Biological Process	GO:0007417	central nervous system development	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:2445271\|PMID:12435628
Biological Process	GO:0007417	central nervous system development	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:2445272\|PMID:12435629
Biological Process	GO:0035017	cuticle pattern formation	FBgn0004859	ci	IMP	Fly	FB:FBrf0190106\|PMID:16413529
Biological Process	GO:0048813	dendrite morphogenesis	FBgn0004859	ci	IMP	Fly	FB:FBrf0190556\|PMID:16547170
Biological Process	GO:0048589	developmental growth	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:1095776\|PMID:9268579
Biological Process	GO:0009953	dorsal/ventral pattern formation	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:2445272\|PMID:12435629
Biological Process	GO:0009953	dorsal/ventral pattern formation	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:3028732\|PMID:14723851
Biological Process	GO:0009953	dorsal/ventral pattern formation	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:3624182\|PMID:16571630
Biological Process	GO:0048566	embryonic gut development	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:1353327\|PMID:10693670
Biological Process	GO:0048558	embryonic gut morphogenesis	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:3608164\|PMID:16247775
Biological Process	GO:0030326	embryonic limb morphogenesis	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:2384366\|PMID:12142027
Biological Process	GO:0030326	embryonic limb morphogenesis	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:2445242\|PMID:12435361
Biological Process	GO:0030326	embryonic limb morphogenesis	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:2445270\|PMID:12435627
Biological Process	GO:0030326	embryonic limb morphogenesis	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:52587\|PMID:8387379
Biological Process	GO:0030326	embryonic limb morphogenesis	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3608261\|PMID:16284117
Biological Process	GO:0048598	embryonic morphogenesis	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:52587\|PMID:8387379
Biological Process	GO:0008544	epidermis development	FBgn0004859	ci	IMP	Fly	FB:FBrf0190556\|PMID:16547170
Biological Process	GO:0048592	eye morphogenesis	FBgn0004859	ci	IMP	Fly	FB:FBrf0193969\|PMID:16651542
Biological Process	GO:0030900	forebrain development	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:3610448\|PMID:16168404
Biological Process	GO:0048699	generation of neurons	ZDB-GENE-041111-162	gli3	IMP	Zfin	ZFIN:ZDB-PUB-050518-2\|PMID:15890329
Biological Process	GO:0048699	generation of neurons	ZDB-GENE-041111-162	gli3	IGI	Zfin	ZFIN:ZDB-PUB-050518-2\|PMID:15890329
Biological Process	GO:0035224	genital disc anterior/posterior pattern formation	FBgn0004859	ci	IEP	Fly	FB:FBrf0088118\|PMID:8798147
Biological Process	GO:0007507	heart development	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3664714\|PMID:11172440
Biological Process	GO:0007442	hindgut morphogenesis	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:2148409\|PMID:11485934
Biological Process	GO:0001822	kidney development	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3664714\|PMID:11172440
Biological Process	GO:0035217	labial disc development	FBgn0004859	ci	IMP	Fly	FB:FBrf0183854\|PMID:15680366
Biological Process	GO:0030324	lung development	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3051935\|PMID:15136151
Biological Process	GO:0030324	lung development	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:1095776\|PMID:9268579
Biological Process	GO:0030879	mammary gland development	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:3656358\|PMID:16914490
Biological Process	GO:0001656	metanephros development	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0045596	negative regulation of cell differentiation	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3608261\|PMID:16284117
Biological Process	GO:0008285	negative regulation of cell proliferation	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0008285	negative regulation of cell proliferation	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0016481	negative regulation of transcription	MGI:95729	Gli3	IDA	Mouse	MGI:MGI:2445270\|PMID:12435627
Biological Process	GO:0021915	neural tube development	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:52587\|PMID:8387379
Biological Process	GO:0048666	neuron development	FBgn0004859	ci	IMP	Fly	FB:FBrf0190556\|PMID:16547170
Biological Process	GO:0048663	neuron fate commitment	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:3610448\|PMID:16168404
Biological Process	GO:0042475	odontogenesis (sensu Vertebrata)	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:1277041\|PMID:9655803
Biological Process	GO:0021631	optic nerve morphogenesis	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:3617688\|PMID:16342201
Biological Process	GO:0007389	pattern specification process	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:2683891\|PMID:14602680
Biological Process	GO:0009954	proximal/distal pattern formation	MGI:95729	Gli3	IMP	Mouse	MGI:MGI:3617688\|PMID:16342201
Biological Process	GO:0009954	proximal/distal pattern formation	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3617688\|PMID:16342201
Biological Process	GO:0045595	regulation of cell differentiation	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3608261\|PMID:16284117
Biological Process	GO:0050767	regulation of neurogenesis	ZDB-GENE-041111-162	gli3	IGI	Zfin	ZFIN:ZDB-PUB-050518-2\|PMID:15890329
Biological Process	GO:0007346	regulation of progression through mitotic cell cycle	FBgn0004859	ci	IMP	Fly	FB:FBrf0135358\|PMID:11279500
Biological Process	GO:0045449	regulation of transcription	ZDB-GENE-041111-162	gli3	ISS	Zfin	ZFIN:ZDB-PUB-041228-22\|PMID:15617692
Biological Process	GO:0007224	smoothened signaling pathway	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0007224	smoothened signaling pathway	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:2445271\|PMID:12435628
Biological Process	GO:0007224	smoothened signaling pathway	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3608261\|PMID:16284117
Biological Process	GO:0007224	smoothened signaling pathway	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3624182\|PMID:16571630
Biological Process	GO:0007224	smoothened signaling pathway	FBgn0004859	ci	IEP	Fly	FB:FBrf0090554\|PMID:8898240
Biological Process	GO:0007224	smoothened signaling pathway	FBgn0004859	ci	IMP	Fly	FB:FBrf0134579\|PMID:11171398
Biological Process	GO:0007224	smoothened signaling pathway	FBgn0004859	ci	IMP	Fly	FB:FBrf0189929\|PMID:16630821
Biological Process	GO:0021776	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3051712\|PMID:15215207
Biological Process	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3051712\|PMID:15215207
Biological Process	GO:0021513	spinal cord dorsal/ventral patterning	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3051712\|PMID:15215207
Biological Process	GO:0021513	spinal cord dorsal/ventral patterning	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3612806\|PMID:16364285
Biological Process	GO:0035277	spiracle morphogenesis, open tracheal system	FBgn0004859	ci	IMP	Fly	FB:FBrf0187474\|PMID:15930099
Biological Process	GO:0035295	tube development	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:1277743\|PMID:9731531
Biological Process	GO:0001658	ureteric bud branching	MGI:95729	Gli3	IGI	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0048100	wing disc anterior/posterior pattern formation	FBgn0004859	ci	IMP	Fly	FB:FBrf0183859\|PMID:15708556

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)