Compare GO annotations for HomoloGene:1576 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0005154	epidermal growth factor receptor binding	P62993	GRB2_HUMAN	IPI	Human	PMID:12577067
Molecular Function	GO:0043560	insulin receptor substrate binding	P62993	GRB2_HUMAN	IPI	Human	PMID:8388384
Molecular Function	GO:0043560	insulin receptor substrate binding	RGD:619758	Grb2	IPI	Rat	RGD:1299201\|PMID:12891559
Molecular Function	GO:0051219	phosphoprotein binding	RGD:619758	Grb2	IPI	Rat	RGD:1599952\|PMID:8910399
Molecular Function	GO:0001784	phosphotyrosine binding	RGD:619758	Grb2	IPI	Rat	RGD:1582133\|PMID:9271418
Molecular Function	GO:0005515	protein binding	MGI:95805	Grb2	IPI	Mouse	MGI:MGI:3694163\|PMID:10373493
Molecular Function	GO:0005515	protein binding	MGI:95805	Grb2	IPI	Mouse	MGI:MGI:3688344\|PMID:15102471
Molecular Function	GO:0005515	protein binding	MGI:95805	Grb2	IPI	Mouse	MGI:MGI:3694172\|PMID:16298995
Molecular Function	GO:0005515	protein binding	MGI:95805	Grb2	IPI	Mouse	MGI:MGI:3513729\|PMID:15467741
Molecular Function	GO:0005515	protein binding	MGI:95805	Grb2	IPI	Mouse	MGI:MGI:3689794\|PMID:15953601
Molecular Function	GO:0005515	protein binding	RGD:619758	Grb2	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	FBgn0004638	drk	IPI	Fly	FB:FBrf0057899\|PMID:8462098
Molecular Function	GO:0005515	protein binding	FBgn0004638	drk	IPI	Fly	FB:FBrf0103310\|PMID:9671493
Molecular Function	GO:0005118	sevenless binding	FBgn0004638	drk	IPI	Fly	FB:FBrf0057899\|PMID:8462098
Molecular Function	GO:0005070	SH3/SH2 adaptor activity	MGI:95805	Grb2	IPI	Mouse	MGI:MGI:62357\|PMID:7689150
Molecular Function	GO:0005070	SH3/SH2 adaptor activity	RGD:619758	Grb2	ISS	Rat	RGD:1580654
Molecular Function	GO:0005070	SH3/SH2 adaptor activity	FBgn0004638	drk	IPI	Fly	FB:FBrf0057899\|PMID:8462098
Molecular Function	GO:0005070	SH3/SH2 adaptor activity	FBgn0004638	drk	ISS	Fly	FB:FBrf0105495
Molecular Function	GO:0005070	SH3/SH2 adaptor activity	WB:WP:CE01784	SEM-5	ISS	Worm	WB:WBPaper00001519\|PMID:1372395
Cellular Component	GO:0005737	cytoplasm	MGI:95805	Grb2	IDA	Mouse	MGI:MGI:3578616\|PMID:15736129
Cellular Component	GO:0005737	cytoplasm	RGD:619758	Grb2	ISS	Rat	RGD:1580654
Cellular Component	GO:0016020	membrane	MGI:95805	Grb2	IDA	Mouse	MGI:MGI:3584078\|PMID:15983387
Cellular Component	GO:0016020	membrane	RGD:619758	Grb2	ISS	Rat	RGD:1580654
Cellular Component	GO:0005886	plasma membrane	FBgn0004638	drk	IDA	Fly	FB:FBrf0057899\|PMID:8462098
Cellular Component	GO:0012506	vesicle membrane	MGI:95805	Grb2	IDA	Mouse	MGI:MGI:2387810\|PMID:12147689
Cellular Component	GO:0012506	vesicle membrane	RGD:619758	Grb2	ISS	Rat	RGD:1580654
Biological Process	GO:0007015	actin filament organization	FBgn0004638	drk	IMP	Fly	FB:FBrf0167741\|PMID:14527345
Biological Process	GO:0008150	biological_process	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0008150	biological_process	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00027756\|PMID:16845399
Biological Process	GO:0016477	cell migration	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00001519\|PMID:1372395
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00005654\|PMID:12529635
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00027756\|PMID:16845399
Biological Process	GO:0001700	embryonic development via the syncytial blastoderm	FBgn0004638	drk	IMP	Fly	FB:FBrf0091142\|PMID:8978055
Biological Process	GO:0007276	gamete generation	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00005654\|PMID:12529635
Biological Process	GO:0040035	hermaphrodite genitalia development	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00005654\|PMID:12529635
Biological Process	GO:0040035	hermaphrodite genitalia development	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0007476	imaginal disc-derived wing morphogenesis	FBgn0004638	drk	IMP	Fly	FB:FBrf0193945\|PMID:16648592
Biological Process	GO:0008286	insulin receptor signaling pathway	P62993	GRB2_HUMAN	IPI	Human	PMID:8388384
Biological Process	GO:0002119	larval development (sensu Nematoda)	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0002119	larval development (sensu Nematoda)	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00027756\|PMID:16845399
Biological Process	GO:0002119	larval development (sensu Nematoda)	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00001519\|PMID:1372395
Biological Process	GO:0007626	locomotory behavior	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0030539	male genitalia development	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00002043\|PMID:7607066
Biological Process	GO:0000165	MAPKKK cascade	MGI:95805	Grb2	IGI	Mouse	MGI:MGI:3513229\|PMID:15569713
Biological Process	GO:0000165	MAPKKK cascade	RGD:619758	Grb2	ISS	Rat	RGD:1580654
Biological Process	GO:0007517	muscle development	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00027119\|PMID:16495308
Biological Process	GO:0040015	negative regulation of body size	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00005654\|PMID:12529635
Biological Process	GO:0040010	positive regulation of growth rate	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0040010	positive regulation of growth rate	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00027756\|PMID:16845399
Biological Process	GO:0051291	protein heterooligomerization	RGD:619758	Grb2	IDA	Rat	RGD:1581313\|PMID:15272025
Biological Process	GO:0007265	Ras protein signal transduction	RGD:619758	Grb2	ISS	Rat	RGD:1580654
Biological Process	GO:0007265	Ras protein signal transduction	FBgn0004638	drk	IPI	Fly	FB:FBrf0057899\|PMID:8462098
Biological Process	GO:0007265	Ras protein signal transduction	FBgn0004638	drk	ISS	Fly	FB:FBrf0057899\|PMID:8462098
Biological Process	GO:0007265	Ras protein signal transduction	FBgn0004638	drk	ISS	Fly	FB:FBrf0105495
Biological Process	GO:0031344	regulation of cell projection organization and biogenesis	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00027119\|PMID:16495308
Biological Process	GO:0008360	regulation of cell shape	FBgn0004638	drk	IMP	Fly	FB:FBrf0167741\|PMID:14527345
Biological Process	GO:0040028	regulation of vulval development (sensu Nematoda)	WBGene00004774	sem-5	IMP	Worm	WB:WBPaper00001519\|PMID:1372395
Biological Process	GO:0045500	sevenless signaling pathway	FBgn0004638	drk	IGI	Fly	FB:FBrf0057899\|PMID:8462098
Biological Process	GO:0045500	sevenless signaling pathway	FBgn0004638	drk	IPI	Fly	FB:FBrf0057899\|PMID:8462098

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)