Compare GO annotations for HomoloGene:1849 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0005515	protein binding	Q99836	MYD88_HUMAN	IPI	Human	PMID:10383454
Molecular Function	GO:0005515	protein binding	Q99836	MYD88_HUMAN	IPI	Human	PMID:11544529
Molecular Function	GO:0005515	protein binding	Q99836	MYD88_HUMAN	IPI	Human	PMID:16286016
Molecular Function	GO:0005515	protein binding	Q99836	MYD88_HUMAN	IPI	Human	PMID:10880445
Molecular Function	GO:0005515	protein binding	MGI:108005	Myd88	IPI	Mouse	MGI:MGI:1889886\|PMID:10854325
Molecular Function	GO:0005515	protein binding	FBgn0033402	Myd88	IPI	Fly	FB:FBrf0139798\|PMID:11606776
Molecular Function	GO:0005515	protein binding	FBgn0033402	Myd88	IPI	Fly	FB:FBrf0193565\|PMID:16782008
Molecular Function	GO:0005102	receptor binding	RGD:735043	Myd88	IPI	Rat	RGD:1302746\|PMID:14962484
Molecular Function	GO:0004871	signal transducer activity	Q99836	MYD88_HUMAN	IEP	Human	PMID:12761501
Molecular Function	GO:0005121	Toll binding	RGD:735043	Myd88	IDA	Rat	RGD:1302746\|PMID:14962484
Cellular Component	GO:0005737	cytoplasm	RGD:735043	Myd88	ISS	Rat	RGD:1580654
Biological Process	GO:0051092	activation of NF-kappaB transcription factor	MGI:108005	Myd88	IGI	Mouse	MGI:MGI:2669022\|PMID:12855817
Biological Process	GO:0051092	activation of NF-kappaB transcription factor	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:2669022\|PMID:12855817
Biological Process	GO:0007166	cell surface receptor linked signal transduction	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:3042099\|PMID:12719478
Biological Process	GO:0007166	cell surface receptor linked signal transduction	RGD:735043	Myd88	ISS	Rat	RGD:1580654
Biological Process	GO:0019221	cytokine and chemokine mediated signaling pathway	RGD:735043	Myd88	IMP	Rat	RGD:1579817\|PMID:15890643
Biological Process	GO:0009953	dorsal/ventral pattern formation	FBgn0033402	Myd88	IMP	Fly	FB:FBrf0155743\|PMID:12524523
Biological Process	GO:0009953	dorsal/ventral pattern formation	FBgn0033402	Myd88	IMP	Fly	FB:FBrf0155935\|PMID:12559494
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB cascade	RGD:735043	Myd88	ISS	Rat	RGD:1580654
Biological Process	GO:0006955	immune response	RGD:735043	Myd88	ISS	Rat	RGD:1580654
Biological Process	GO:0016064	immunoglobulin mediated immune response	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:3575992\|PMID:15800576
Biological Process	GO:0016064	immunoglobulin mediated immune response	RGD:735043	Myd88	ISS	Rat	RGD:1580654
Biological Process	GO:0045087	innate immune response	ZDB-GENE-040219-3	myd88	IMP	Zfin	ZFIN:ZDB-PUB-060323-32\|PMID:16552074
Biological Process	GO:0045351	interferon type I biosynthetic process	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:3575992\|PMID:15800576
Biological Process	GO:0045351	interferon type I biosynthetic process	RGD:735043	Myd88	ISS	Rat	RGD:1580654
Biological Process	GO:0007254	JNK cascade	RGD:735043	Myd88	IMP	Rat	RGD:1579817\|PMID:15890643
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:2669022\|PMID:12855817
Biological Process	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:2670551\|PMID:12872135
Biological Process	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	MGI:108005	Myd88	IGI	Mouse	MGI:MGI:3042099\|PMID:12719478
Biological Process	GO:0045080	positive regulation of chemokine biosynthetic process	MGI:108005	Myd88	IGI	Mouse	MGI:MGI:2669022\|PMID:12855817
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	Q99836	MYD88_HUMAN	IEP	Human	PMID:12761501
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:2669022\|PMID:12855817
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	MGI:108005	Myd88	IGI	Mouse	MGI:MGI:2669022\|PMID:12855817
Biological Process	GO:0046330	positive regulation of JNK cascade	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:2669022\|PMID:12855817
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	RGD:735043	Myd88	IMP	Rat	RGD:1579817\|PMID:15890643
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	RGD:735043	Myd88	IMP	Rat	RGD:1579817\|PMID:15890643
Biological Process	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	RGD:735043	Myd88	ISS	Rat	RGD:1580654
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:3042099\|PMID:12719478
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	MGI:108005	Myd88	IGI	Mouse	MGI:MGI:2670551\|PMID:12872135
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:2670551\|PMID:12872135
Biological Process	GO:0032496	response to lipopolysaccharide	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:2669022\|PMID:12855817
Biological Process	GO:0032496	response to lipopolysaccharide	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:2670551\|PMID:12872135
Biological Process	GO:0032496	response to lipopolysaccharide	MGI:108005	Myd88	IGI	Mouse	MGI:MGI:2670551\|PMID:12872135
Biological Process	GO:0032496	response to lipopolysaccharide	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:3042099\|PMID:12719478
Biological Process	GO:0002238	response to molecule of fungal origin	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:3042099\|PMID:12719478
Biological Process	GO:0009615	response to virus	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:3037412\|PMID:14993594
Biological Process	GO:0009615	response to virus	MGI:108005	Myd88	IMP	Mouse	MGI:MGI:3575992\|PMID:15800576
Biological Process	GO:0009615	response to virus	RGD:735043	Myd88	ISS	Rat	RGD:1580654
Biological Process	GO:0008063	Toll signaling pathway	RGD:735043	Myd88	IDA	Rat	RGD:1302746\|PMID:14962484
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	RGD:735043	Myd88	ISS	Rat	RGD:1580654

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)