Compare GO annotations for HomoloGene:20242 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0043176	amine binding	WB:WP:CE28481	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Molecular Function	GO:0043176	amine binding	WB:WP:CE38526	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Molecular Function	GO:0008227	amine receptor activity	FBgn0013743	5-HT2	ISS	Fly	FB:FBrf0152099\|PMID:12163486
Molecular Function	GO:0016609	G-protein coupled serotonin receptor activity	FBgn0013743	5-HT2	ISS	Fly	FB:FBrf0129744\|PMID:10908591
Molecular Function	GO:0005515	protein binding	P28335	5HT2C_HUMAN	IPI	Human	PMID:16319069
Molecular Function	GO:0051378	serotonin binding	WB:WP:CE28481	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Molecular Function	GO:0051378	serotonin binding	WB:WP:CE38526	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Molecular Function	GO:0004993	serotonin receptor activity	MGI:96281	Htr2c	ISS	Mouse	MGI:MGI:2154458
Molecular Function	GO:0004993	serotonin receptor activity	RGD:2848	Htr2c	IMP	Rat	RGD:1358734\|PMID:15663485
Molecular Function	GO:0004993	serotonin receptor activity	RGD:2848	Htr2c	ISS	Rat	RGD:1580654
Molecular Function	GO:0004993	serotonin receptor activity	RGD:2848	Htr2c	ISS	Rat	RGD:1580655
Molecular Function	GO:0004993	serotonin receptor activity	RGD:2848	Htr2c	IDA	Rat	RGD:null
Molecular Function	GO:0004993	serotonin receptor activity	WB:WP:CE28481	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Molecular Function	GO:0004993	serotonin receptor activity	WB:WP:CE38526	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Cellular Component	GO:0009897	external side of plasma membrane	MGI:96281	Htr2c	ISS	Mouse	MGI:MGI:2154458
Cellular Component	GO:0009897	external side of plasma membrane	RGD:2848	Htr2c	IDA	Rat	RGD:null
Cellular Component	GO:0016021	integral to membrane	RGD:2848	Htr2c	ISS	Rat	RGD:1580654
Cellular Component	GO:0016021	integral to membrane	FBgn0013743	5-HT2	ISS	Fly	FB:FBrf0129744\|PMID:10908591
Cellular Component	GO:0005887	integral to plasma membrane	RGD:2848	Htr2c	ISS	Rat	RGD:1580655
Cellular Component	GO:0005886	plasma membrane	RGD:2848	Htr2c	IMP	Rat	RGD:1358734\|PMID:15663485
Cellular Component	GO:0005886	plasma membrane	FBgn0013743	5-HT2	IDA	Fly	FB:FBrf0081644\|PMID:7777527
Cellular Component	GO:0005886	plasma membrane	FBgn0013743	5-HT2	ISS	Fly	FB:FBrf0081644\|PMID:7777527
Cellular Component	GO:0005886	plasma membrane	WB:WP:CE28481	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Cellular Component	GO:0005886	plasma membrane	WB:WP:CE38526	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Biological Process	GO:0035095	behavioral response to nicotine	RGD:2848	Htr2c	IMP	Rat	RGD:1624994\|PMID:17473916
Biological Process	GO:0019722	calcium-mediated signaling	WB:WP:CE28481	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Biological Process	GO:0019722	calcium-mediated signaling	WB:WP:CE38526	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Biological Process	GO:0007631	feeding behavior	RGD:2848	Htr2c	ISS	Rat	RGD:1580655
Biological Process	GO:0007631	feeding behavior	RGD:2848	Htr2c	IMP	Rat	RGD:1625006\|PMID:15705738
Biological Process	GO:0031583	G-protein signaling, phospholipase D activating pathway	RGD:2848	Htr2c	IMP	Rat	RGD:1598460\|PMID:12435801
Biological Process	GO:0007377	germ-band extension	FBgn0013743	5-HT2	IMP	Fly	FB:FBrf0111346\|PMID:10495273
Biological Process	GO:0048016	inositol phosphate-mediated signaling	MGI:96281	Htr2c	ISS	Mouse	MGI:MGI:2154458
Biological Process	GO:0048016	inositol phosphate-mediated signaling	RGD:2848	Htr2c	IDA	Rat	RGD:null
Biological Process	GO:0045963	negative regulation of dopamine metabolic process	RGD:2848	Htr2c	IMP	Rat	RGD:1625003\|PMID:17018023
Biological Process	GO:0040013	negative regulation of locomotion	RGD:2848	Htr2c	IMP	Rat	RGD:1625005\|PMID:15896731
Biological Process	GO:0031100	organ regeneration	RGD:2848	Htr2c	IEP	Rat	RGD:1624998\|PMID:17258772
Biological Process	GO:0014057	positive regulation of acetylcholine secretion	RGD:2848	Htr2c	IMP	Rat	RGD:1625007\|PMID:15266551
Biological Process	GO:0014054	positive regulation of gamma-aminobutyric acid secretion	RGD:2848	Htr2c	IMP	Rat	RGD:1625001\|PMID:17043669
Biological Process	GO:0045907	positive regulation of vasoconstriction	RGD:2848	Htr2c	IMP	Rat	RGD:1625008\|PMID:15118345
Biological Process	GO:0051930	regulation of sensory perception of pain	RGD:2848	Htr2c	IMP	Rat	RGD:1624996\|PMID:17451674
Biological Process	GO:0042493	response to drug	RGD:2848	Htr2c	IMP	Rat	RGD:1625004\|PMID:16807362
Biological Process	GO:0007210	serotonin receptor signaling pathway	RGD:2848	Htr2c	ISS	Rat	RGD:1580655
Biological Process	GO:0007210	serotonin receptor signaling pathway	FBgn0013743	5-HT2	ISS	Fly	FB:FBrf0129744\|PMID:10908591
Biological Process	GO:0007210	serotonin receptor signaling pathway	WB:WP:CE28481	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Biological Process	GO:0007210	serotonin receptor signaling pathway	WB:WP:CE38526	SER-1	IDA	Worm	WB:WBPaper00003432\|PMID:10098838
Biological Process	GO:0007208	serotonin receptor, phospholipase C activating pathway	RGD:2848	Htr2c	IDA	Rat	RGD:1598460\|PMID:12435801
Biological Process	GO:0007268	synaptic transmission	RGD:2848	Htr2c	ISS	Rat	RGD:1580655

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)