Compare GO annotations for HomoloGene:20391 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0048185	activin binding	MGI:102806	Acvr2a	IPI	Mouse	MGI:MGI:59666\|PMID:1646080
Molecular Function	GO:0048185	activin binding	FBgn0003169	put	IDA	Fly	FB:FBrf0064404\|PMID:8415726
Molecular Function	GO:0048185	activin binding	FBgn0003169	put	IDA	Fly	FB:FBrf0066967\|PMID:8289834
Molecular Function	GO:0017002	activin receptor activity	P27037	AVR2A_HUMAN	IDA	Human	PMID:12665502
Molecular Function	GO:0017002	activin receptor activity	FBgn0003169	put	IDA	Fly	FB:FBrf0064404\|PMID:8415726
Molecular Function	GO:0016362	activin receptor activity, type II	RGD:70911	Acvr2a	IDA	Rat	RGD:728125\|PMID:12844345
Molecular Function	GO:0016362	activin receptor activity, type II	FBgn0003169	put	ISS	Fly	FB:FBrf0064404\|PMID:8415726
Molecular Function	GO:0019838	growth factor binding	MGI:102806	Acvr2a	IPI	Mouse	MGI:MGI:2137985\|PMID:11459935
Molecular Function	GO:0019838	growth factor binding	MGI:102806	Acvr2a	IMP	Mouse	MGI:MGI:2389524\|PMID:12414726
Molecular Function	GO:0048186	inhibin beta-A binding	P27037	AVR2A_HUMAN	IDA	Human	PMID:7890768
Molecular Function	GO:0048186	inhibin beta-A binding	MGI:102806	Acvr2a	IDA	Mouse	MGI:MGI:3694156\|PMID:7890768
Molecular Function	GO:0043621	protein self-association	MGI:102806	Acvr2a	IPI	Mouse	MGI:MGI:80279\|PMID:8612709
Molecular Function	GO:0004713	protein-tyrosine kinase activity	RGD:70911	Acvr2a	ISS	Rat	RGD:1580654
Molecular Function	GO:0005024	transforming growth factor beta receptor activity	FBgn0003169	put	IGI	Fly	FB:FBrf0080361\|PMID:7697719
Molecular Function	GO:0005026	transforming growth factor beta receptor activity, type II	FBgn0003169	put	ISS	Fly	FB:FBrf0080361\|PMID:7697719
Cellular Component	GO:0048179	activin receptor complex	FBgn0003169	put	IPI	Fly	FB:FBrf0066967\|PMID:8289834
Cellular Component	GO:0005737	cytoplasm	P27037	AVR2A_HUMAN	IDA	Human	PMID:14738881
Cellular Component	GO:0005615	extracellular space	RGD:70911	Acvr2a	ISS	Rat	RGD:1580654
Cellular Component	GO:0016021	integral to membrane	RGD:70911	Acvr2a	ISS	Rat	RGD:1580654
Cellular Component	GO:0005887	integral to plasma membrane	RGD:70911	Acvr2a	ISS	Rat	RGD:1580655
Cellular Component	GO:0005886	plasma membrane	FBgn0003169	put	ISS	Fly	FB:FBrf0064404\|PMID:8415726
Cellular Component	GO:0005886	plasma membrane	FBgn0003169	put	ISS	Fly	FB:FBrf0080361\|PMID:7697719
Biological Process	GO:0009952	anterior/posterior pattern formation	MGI:102806	Acvr2a	IGI	Mouse	MGI:MGI:1344152\|PMID:10452853
Biological Process	GO:0009952	anterior/posterior pattern formation	MGI:102806	Acvr2a	IGI	Mouse	MGI:MGI:3689276\|PMID:16991118
Biological Process	GO:0007368	determination of left/right symmetry	MGI:102806	Acvr2a	IGI	Mouse	MGI:MGI:3689276\|PMID:16991118
Biological Process	GO:0007391	dorsal closure	FBgn0003169	put	IMP	Fly	FB:FBrf0080209\|PMID:7697720
Biological Process	GO:0009953	dorsal/ventral pattern formation	FBgn0003169	put	IMP	Fly	FB:FBrf0080209\|PMID:7697720
Biological Process	GO:0048706	embryonic skeletal development	MGI:102806	Acvr2a	IMP	Mouse	MGI:MGI:71660\|PMID:7885474
Biological Process	GO:0048276	gastrulation (sensu Vertebrata)	MGI:102806	Acvr2a	IGI	Mouse	MGI:MGI:1344152\|PMID:10452853
Biological Process	GO:0042078	germ-line stem cell division	FBgn0003169	put	IMP	Fly	FB:FBrf0103396\|PMID:9695953
Biological Process	GO:0030718	germ-line stem cell maintenance	FBgn0003169	put	IMP	Fly	FB:FBrf0103396\|PMID:9695953
Biological Process	GO:0008258	head involution	FBgn0003169	put	IMP	Fly	FB:FBrf0080209\|PMID:7697720
Biological Process	GO:0008584	male gonad development	MGI:102806	Acvr2a	IMP	Mouse	MGI:MGI:71660\|PMID:7885474
Biological Process	GO:0007443	Malpighian tubule morphogenesis	FBgn0003169	put	IMP	Fly	FB:FBrf0111391\|PMID:10502111
Biological Process	GO:0007498	mesoderm development	MGI:102806	Acvr2a	IMP	Mouse	MGI:MGI:1344152\|PMID:10452853
Biological Process	GO:0048666	neuron development	FBgn0003169	put	IMP	Fly	FB:FBrf0190369\|PMID:16437159
Biological Process	GO:0007424	open tracheal system development	FBgn0003169	put	IMP	Fly	FB:FBrf0187390\|PMID:15848387
Biological Process	GO:0043084	penile erection	MGI:102806	Acvr2a	IMP	Mouse	MGI:MGI:3691726\|PMID:16093358
Biological Process	GO:0032927	positive regulation of activin receptor signaling pathway	P27037	AVR2A_HUMAN	IDA	Human	PMID:12665502
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	P27037	AVR2A_HUMAN	IDA	Human	PMID:9032295
Biological Process	GO:0007428	primary branching, open tracheal system	FBgn0003169	put	IMP	Fly	FB:FBrf0148947\|PMID:12015974
Biological Process	GO:0050999	regulation of nitric-oxide synthase activity	MGI:102806	Acvr2a	IMP	Mouse	MGI:MGI:3691726\|PMID:16093358
Biological Process	GO:0060011	Sertoli cell proliferation	MGI:102806	Acvr2a	IMP	Mouse	MGI:MGI:2151283\|PMID:11416011
Biological Process	GO:0042713	sperm ejaculation	MGI:102806	Acvr2a	IMP	Mouse	MGI:MGI:3691726\|PMID:16093358
Biological Process	GO:0007283	spermatogenesis	MGI:102806	Acvr2a	IGI	Mouse	MGI:MGI:3624913\|PMID:11459797
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	FBgn0003169	put	IMP	Fly	FB:FBrf0080209\|PMID:7697720
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	FBgn0003169	put	IGI	Fly	FB:FBrf0080361\|PMID:7697719
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	FBgn0003169	put	IMP	Fly	FB:FBrf0080361\|PMID:7697719
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	RGD:70911	Acvr2a	ISS	Rat	RGD:1580655

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)