Compare GO annotations for HomoloGene:2063 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0005524	ATP binding	SPBC409.07c	wis1	ISS	Pombe	GOC:unpublished
Molecular Function	GO:0004708	MAP kinase kinase activity	MGI:1346866	Map2k1	IMP	Mouse	MGI:MGI:2176412\|PMID:11841548
Molecular Function	GO:0004708	MAP kinase kinase activity	RGD:70495	Map2k1	ISS	Rat	RGD:1580654
Molecular Function	GO:0004708	MAP kinase kinase activity	RGD:70495	Map2k1	ISS	Rat	RGD:1580655
Molecular Function	GO:0004708	MAP kinase kinase activity	RGD:70495	Map2k1	IDA	Rat	RGD:1582177\|PMID:7624324
Molecular Function	GO:0004708	MAP kinase kinase activity	FBgn0010269	Dsor1	ISS	Fly	FB:FBrf0085669
Molecular Function	GO:0004708	MAP kinase kinase activity	FBgn0010269	Dsor1	ISS	Fly	FB:FBrf0093573\|PMID:9136016
Molecular Function	GO:0004708	MAP kinase kinase activity	gene:3355478	ATMKK2	ISS	Tair	TAIR:Publication:1893\|PMID:9878570
Molecular Function	GO:0004708	MAP kinase kinase activity	gene:3355478	ATMKK2	IDA	Tair	TAIR:Publication:501712959\|PMID:15225555
Molecular Function	GO:0004708	MAP kinase kinase activity	S000003664	PBS2	IMP	Yeast	SGD_REF:S000051778\|PMID:7624781
Molecular Function	GO:0004708	MAP kinase kinase activity	S000003664	PBS2	ISS	Yeast	SGD_REF:S000046190\|PMID:7681220
Molecular Function	GO:0004708	MAP kinase kinase activity	SPBC409.07c	wis1	IGI	Pombe	PMID:8649397
Molecular Function	GO:0005078	MAP-kinase scaffold activity	S000003664	PBS2	IPI	Yeast	SGD_REF:S000049858\|PMID:9180081
Molecular Function	GO:0005515	protein binding	Q02750	MP2K1_HUMAN	IPI	Human	PMID:15299019
Molecular Function	GO:0005515	protein binding	RGD:70495	Map2k1	ISS	Rat	RGD:1580655
Molecular Function	GO:0005515	protein binding	RGD:70495	Map2k1	IDA	Rat	RGD:1582174\|PMID:12401521
Molecular Function	GO:0005515	protein binding	SPBC409.07c	wis1	IPI	Pombe	PMID:9585506
Cellular Component	GO:0005935	cellular bud neck	S000003664	PBS2	IDA	Yeast	SGD_REF:S000049607\|PMID:10980703
Cellular Component	GO:0005934	cellular bud tip	S000003664	PBS2	IDA	Yeast	SGD_REF:S000049607\|PMID:10980703
Cellular Component	GO:0005737	cytoplasm	S000003664	PBS2	IDA	Yeast	SGD_REF:S000058374\|PMID:9755161
Cellular Component	GO:0005737	cytoplasm	SPBC409.07c	wis1	IDA	Pombe	PMID:9585506
Cellular Component	GO:0005829	cytosol	RGD:70495	Map2k1	IDA	Rat	RGD:70317\|PMID:9779826
Cellular Component	GO:0005829	cytosol	SPBC409.07c	wis1	IDA	Pombe	PMID:16823372
Cellular Component	GO:0005794	Golgi apparatus	RGD:70495	Map2k1	IDA	Rat	RGD:1582173\|PMID:12695496
Cellular Component	GO:0005634	nucleus	SPBC409.07c	wis1	IDA	Pombe	PMID:12181336
Biological Process	GO:0007015	actin filament organization	S000003664	PBS2	IMP	Yeast	SGD_REF:S000052507\|PMID:7941729
Biological Process	GO:0000169	activation of MAPK activity during osmolarity sensing	S000003664	PBS2	IMP	Yeast	SGD_REF:S000051778\|PMID:7624781
Biological Process	GO:0006928	cell motility	RGD:70495	Map2k1	ISS	Rat	RGD:1580655
Biological Process	GO:0008283	cell proliferation	RGD:70495	Map2k1	IDA	Rat	RGD:1582172\|PMID:16481589
Biological Process	GO:0006935	chemotaxis	RGD:70495	Map2k1	ISS	Rat	RGD:1580655
Biological Process	GO:0009631	cold acclimation	gene:3355478	ATMKK2	IMP	Tair	TAIR:Publication:501712959\|PMID:15225555
Biological Process	GO:0009790	embryonic development	WBGene00003186	mek-2	IMP	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00003186	mek-2	IMP	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0001703	gastrulation with mouth forming first	WBGene00003186	mek-2	IMP	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0042386	hemocyte differentiation	FBgn0010269	Dsor1	IGI	Fly	FB:FBrf0147160
Biological Process	GO:0006972	hyperosmotic response	S000003664	PBS2	IMP	Yeast	SGD_REF:S000046190\|PMID:7681220
Biological Process	GO:0030216	keratinocyte differentiation	MGI:1346866	Map2k1	IMP	Mouse	MGI:MGI:2176412\|PMID:11841548
Biological Process	GO:0030216	keratinocyte differentiation	RGD:70495	Map2k1	ISS	Rat	RGD:1580654
Biological Process	GO:0000165	MAPKKK cascade	gene:3355478	ATMKK2	IGI	Tair	TAIR:Publication:1893\|PMID:9878570
Biological Process	GO:0007067	mitosis	RGD:70495	Map2k1	IDA	Rat	RGD:1582173\|PMID:12695496
Biological Process	GO:0030182	neuron differentiation	MGI:1346866	Map2k1	IMP	Mouse	MGI:MGI:3050703\|PMID:15145949
Biological Process	GO:0030182	neuron differentiation	RGD:70495	Map2k1	ISS	Rat	RGD:1580654
Biological Process	GO:0000208	nuclear translocation of MAPK during osmolarity sensing	S000003664	PBS2	IMP	Yeast	SGD_REF:S000080903\|PMID:15707964
Biological Process	GO:0007231	osmosensory signaling pathway	S000003664	PBS2	IMP	Yeast	SGD_REF:S000051778\|PMID:7624781
Biological Process	GO:0006468	protein amino acid phosphorylation	S000003664	PBS2	IMP	Yeast	SGD_REF:S000051778\|PMID:7624781
Biological Process	GO:0006468	protein amino acid phosphorylation	SPBC409.07c	wis1	IGI	Pombe	PMID:8886983
Biological Process	GO:0007265	Ras protein signal transduction	WBGene00003186	mek-2	IGI	Worm	WB:WBPaper00005135\|PMID:11861555
Biological Process	GO:0007346	regulation of progression through mitotic cell cycle	SPBC409.07c	wis1	IMP	Pombe	PMID:1756736
Biological Process	GO:0043555	regulation of translation in response to stress	SPBC409.07c	wis1	IMP	Pombe	PMID:7859738
Biological Process	GO:0000003	reproduction	WBGene00003186	mek-2	IMP	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0000003	reproduction	WBGene00003186	mek-2	IMP	Worm	WB:WBPaper00025054\|PMID:15791247
Biological Process	GO:0046685	response to arsenic	SPBC409.07c	wis1	IMP	Pombe	PMID:16087744
Biological Process	GO:0009409	response to cold	gene:3355478	ATMKK2	IDA	Tair	TAIR:Publication:501712959\|PMID:15225555
Biological Process	GO:0009409	response to cold	gene:3355478	ATMKK2	IMP	Tair	TAIR:Publication:501712959\|PMID:15225555
Biological Process	GO:0051384	response to glucocorticoid stimulus	RGD:70495	Map2k1	IDA	Rat	RGD:625388\|PMID:11872750
Biological Process	GO:0042542	response to hydrogen peroxide	SPBC409.07c	wis1	IMP	Pombe	PMID:16087744
Biological Process	GO:0006979	response to oxidative stress	RGD:70495	Map2k1	IDA	Rat	RGD:1582172\|PMID:16481589
Biological Process	GO:0009651	response to salt stress	gene:3355478	ATMKK2	IGI	Tair	TAIR:Publication:501712959\|PMID:15225555
Biological Process	GO:0009651	response to salt stress	gene:3355478	ATMKK2	IDA	Tair	TAIR:Publication:501712959\|PMID:15225555
Biological Process	GO:0009651	response to salt stress	gene:3355478	ATMKK2	IMP	Tair	TAIR:Publication:501712959\|PMID:15225555
Biological Process	GO:0007165	signal transduction	RGD:70495	Map2k1	ISS	Rat	RGD:1580655
Biological Process	GO:0007165	signal transduction	FBgn0010269	Dsor1	IGI	Fly	FB:FBrf0057887\|PMID:8381718
Biological Process	GO:0007165	signal transduction	FBgn0010269	Dsor1	IMP	Fly	FB:FBrf0076505\|PMID:7958887
Biological Process	GO:0040025	vulval development (sensu Nematoda)	WBGene00003186	mek-2	IGI	Worm	WB:WBPaper00005135\|PMID:11861555

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)