Compare GO annotations for HomoloGene:210 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0043531	ADP binding	P43246	MSH2_HUMAN	IDA	Human	PMID:15105434
Molecular Function	GO:0005524	ATP binding	P43246	MSH2_HUMAN	IDA	Human	PMID:15105434
Molecular Function	GO:0005524	ATP binding	S000005450	MSH2	IDA	Yeast	SGD_REF:S000051290\|PMID:9545323
Molecular Function	GO:0016887	ATPase activity	P43246	MSH2_HUMAN	IDA	Human	PMID:16403449
Molecular Function	GO:0016887	ATPase activity	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:2679186\|PMID:14568978
Molecular Function	GO:0016887	ATPase activity	S000005450	MSH2	IDA	Yeast	SGD_REF:S000047828\|PMID:9819445
Molecular Function	GO:0019237	centromeric DNA binding	MGI:101816	Msh2	IDA	Mouse	MGI:MGI:3612193\|PMID:16260499
Molecular Function	GO:0019237	centromeric DNA binding	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Molecular Function	GO:0003684	damaged DNA binding	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1351797\|PMID:10545954
Molecular Function	GO:0003684	damaged DNA binding	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:74950\|PMID:7628020
Molecular Function	GO:0003684	damaged DNA binding	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Molecular Function	GO:0003684	damaged DNA binding	gene:3354686	MSH2	IDA	Tair	TAIR:Publication:329\|PMID:10852942
Molecular Function	GO:0032181	dinucleotide repeat insertion binding	P43246	MSH2_HUMAN	IDA	Human	PMID:8942985
Molecular Function	GO:0003677	DNA binding	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1351797\|PMID:10545954
Molecular Function	GO:0003677	DNA binding	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Molecular Function	GO:0032135	DNA insertion or deletion binding	S000005450	MSH2	IDA	Yeast	SGD_REF:S000057936\|PMID:8805366
Molecular Function	GO:0000406	double-strand/single-strand DNA junction binding	S000005450	MSH2	IDA	Yeast	SGD_REF:S000116723\|PMID:16781730
Molecular Function	GO:0000400	four-way junction DNA binding	P43246	MSH2_HUMAN	IDA	Human	PMID:12034830
Molecular Function	GO:0000400	four-way junction DNA binding	S000005450	MSH2	IDA	Yeast	SGD_REF:S000051837\|PMID:9018043
Molecular Function	GO:0000400	four-way junction DNA binding	S000005450	MSH2	IDA	Yeast	SGD_REF:S000055596\|PMID:10066781
Molecular Function	GO:0032137	guanine/thymine mispair binding	P43246	MSH2_HUMAN	IDA	Human	PMID:11809883
Molecular Function	GO:0032137	guanine/thymine mispair binding	P43246	MSH2_HUMAN	IDA	Human	PMID:8942985
Molecular Function	GO:0032137	guanine/thymine mispair binding	MGI:101816	Msh2	IDA	Mouse	MGI:MGI:3653556\|PMID:16713580
Molecular Function	GO:0032137	guanine/thymine mispair binding	MGI:101816	Msh2	ISS	Mouse	MGI:MGI:3653556\|PMID:16713580
Molecular Function	GO:0032137	guanine/thymine mispair binding	S000005450	MSH2	IDA	Yeast	SGD_REF:S000051967\|PMID:8816473
Molecular Function	GO:0032137	guanine/thymine mispair binding	ZDB-GENE-040426-2932	msh2	IDA	Zfin	ZFIN:ZDB-PUB-041021-3\|PMID:15488992
Molecular Function	GO:0032137	guanine/thymine mispair binding	ZDB-GENE-040426-2932	msh2	IGI	Zfin	ZFIN:ZDB-PUB-041021-3\|PMID:15488992
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	MGI:101816	Msh2	IDA	Mouse	MGI:MGI:60112\|PMID:8492116
Molecular Function	GO:0000404	loop DNA binding	S000005450	MSH2	IDA	Yeast	SGD_REF:S000116723\|PMID:16781730
Molecular Function	GO:0000287	magnesium ion binding	P43246	MSH2_HUMAN	IDA	Human	PMID:16403449
Molecular Function	GO:0030983	mismatched DNA binding	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:76015\|PMID:7550317
Molecular Function	GO:0030983	mismatched DNA binding	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:3029112\|PMID:14744764
Molecular Function	GO:0030983	mismatched DNA binding	gene:3354686	MSH2	IDA	Tair	TAIR:Publication:501680116\|PMID:11550901
Molecular Function	GO:0032405	MutLalpha complex binding	P43246	MSH2_HUMAN	IDA	Human	PMID:16403449
Molecular Function	GO:0032357	oxidized purine DNA binding	P43246	MSH2_HUMAN	IDA	Human	PMID:11801590
Molecular Function	GO:0032357	oxidized purine DNA binding	P43246	MSH2_HUMAN	IDA	Human	PMID:11756455
Molecular Function	GO:0005515	protein binding	RGD:620786	Msh2	ISS	Rat	RGD:1580655
Molecular Function	GO:0005515	protein binding	gene:3354686	MSH2	IDA	Tair	TAIR:Publication:329\|PMID:10852942
Molecular Function	GO:0042803	protein homodimerization activity	P43246	MSH2_HUMAN	IDA	Human	PMID:8942985
Molecular Function	GO:0032138	single base insertion or deletion binding	S000005450	MSH2	IDA	Yeast	SGD_REF:S000051967\|PMID:8816473
Molecular Function	GO:0032138	single base insertion or deletion binding	S000005450	MSH2	IMP	Yeast	SGD_REF:S000047266\|PMID:9111312
Molecular Function	GO:0032142	single guanine insertion binding	P43246	MSH2_HUMAN	IDA	Human	PMID:8942985
Molecular Function	GO:0032143	single thymine insertion binding	P43246	MSH2_HUMAN	IDA	Human	PMID:8942985
Molecular Function	GO:0003697	single-stranded DNA binding	P43246	MSH2_HUMAN	IDA	Human	PMID:11809883
Molecular Function	GO:0000403	Y-form DNA binding	S000005450	MSH2	IDA	Yeast	SGD_REF:S000116723\|PMID:16781730
Cellular Component	GO:0032301	MutSalpha complex	P43246	MSH2_HUMAN	IDA	Human	PMID:8942985
Cellular Component	GO:0032301	MutSalpha complex	MGI:101816	Msh2	IDA	Mouse	MGI:MGI:3653556\|PMID:16713580
Cellular Component	GO:0032301	MutSalpha complex	S000005450	MSH2	IPI	Yeast	SGD_REF:S000051967\|PMID:8816473
Cellular Component	GO:0032302	MutSbeta complex	P43246	MSH2_HUMAN	IDA	Human	PMID:8942985
Cellular Component	GO:0032302	MutSbeta complex	S000005450	MSH2	IPI	Yeast	SGD_REF:S000057936\|PMID:8805366
Cellular Component	GO:0000228	nuclear chromosome	S000005450	MSH2	IDA	Yeast	SGD_REF:S000044043\|PMID:10882115
Cellular Component	GO:0005634	nucleus	MGI:101816	Msh2	IDA	Mouse	MGI:MGI:1195422\|PMID:9443401
Cellular Component	GO:0005634	nucleus	MGI:101816	Msh2	IDA	Mouse	MGI:MGI:3029112\|PMID:14744764
Cellular Component	GO:0005634	nucleus	RGD:620786	Msh2	ISS	Rat	RGD:1580655
Cellular Component	GO:0005634	nucleus	RGD:620786	Msh2	IMP	Rat	RGD:1580607\|PMID:9473709
Cellular Component	GO:0005634	nucleus	S000005450	MSH2	IDA	Yeast	SGD_REF:S000074185\|PMID:14562095
Biological Process	GO:0006915	apoptosis	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1334080\|PMID:10097137
Biological Process	GO:0006915	apoptosis	MGI:101816	Msh2	IGI	Mouse	MGI:MGI:1334080\|PMID:10097137
Biological Process	GO:0006915	apoptosis	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:3029112\|PMID:14744764
Biological Process	GO:0030183	B cell differentiation	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1275867\|PMID:9697843
Biological Process	GO:0019724	B cell mediated immunity	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1275867\|PMID:9697843
Biological Process	GO:0019724	B cell mediated immunity	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1329767\|PMID:9927509
Biological Process	GO:0006284	base-excision repair	P43246	MSH2_HUMAN	IDA	Human	PMID:8942985
Biological Process	GO:0007050	cell cycle arrest	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:2667543\|PMID:12687013
Biological Process	GO:0007050	cell cycle arrest	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0006928	cell motility	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1275866\|PMID:9697842
Biological Process	GO:0030466	chromatin silencing at silent mating-type cassette	S000005450	MSH2	IGI	Yeast	SGD_REF:S000086657\|PMID:16157874
Biological Process	GO:0008340	determination of adult life span	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1351797\|PMID:10545954
Biological Process	GO:0008340	determination of adult life span	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0006310	DNA recombination	S000005450	MSH2	IMP	Yeast	SGD_REF:S000081889\|PMID:15920474
Biological Process	GO:0006281	DNA repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:2667543\|PMID:12687013
Biological Process	GO:0006281	DNA repair	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0001701	in utero embryonic development	MGI:101816	Msh2	IGI	Mouse	MGI:MGI:1096207\|PMID:9288110
Biological Process	GO:0031573	intra-S DNA damage checkpoint	MGI:101816	Msh2	IGI	Mouse	MGI:MGI:3512823\|PMID:15533840
Biological Process	GO:0031573	intra-S DNA damage checkpoint	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0045190	isotype switching	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1342394\|PMID:10430621
Biological Process	GO:0045190	isotype switching	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:2662086\|PMID:12743174
Biological Process	GO:0043570	maintenance of DNA repeat elements	P43246	MSH2_HUMAN	IMP	Human	PMID:16388310
Biological Process	GO:0043570	maintenance of DNA repeat elements	FBgn0015546	spel1	IMP	Fly	FB:FBrf0108178\|PMID:10077620
Biological Process	GO:0043570	maintenance of DNA repeat elements	FBgn0015546	spel1	IMP	Fly	FB:FBrf0145154\|PMID:11815247
Biological Process	GO:0043570	maintenance of DNA repeat elements	FBgn0015546	spel1	IMP	Fly	FB:FBrf0152211\|PMID:12150919
Biological Process	GO:0006311	meiotic gene conversion	S000005450	MSH2	IMP	Yeast	SGD_REF:S000054454\|PMID:1334021
Biological Process	GO:0000710	meiotic mismatch repair	S000005450	MSH2	IMP	Yeast	SGD_REF:S000054454\|PMID:1334021
Biological Process	GO:0000710	meiotic mismatch repair	S000005450	MSH2	IMP	Yeast	SGD_REF:S000055135\|PMID:8056309
Biological Process	GO:0000710	meiotic mismatch repair	S000005450	MSH2	IMP	Yeast	SGD_REF:S000115808\|PMID:16702432
Biological Process	GO:0006298	mismatch repair	P43246	MSH2_HUMAN	IDA	Human	PMID:7923193
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IGI	Mouse	MGI:MGI:3692242\|PMID:16728433
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:74950\|PMID:7628020
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1096207\|PMID:9288110
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1350445\|PMID:10581038
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:2388857\|PMID:12531017
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1861016\|PMID:10874005
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:2176101\|PMID:11890935
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1889760\|PMID:10992298
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:82395\|PMID:8706033
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IDA	Mouse	MGI:MGI:87767\|PMID:9157971
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IDA	Mouse	MGI:MGI:894568\|PMID:9244348
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1926519\|PMID:11046134
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:3692242\|PMID:16728433
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	ISS	Mouse	MGI:MGI:2150850\|PMID:11555625
Biological Process	GO:0006298	mismatch repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:3029112\|PMID:14744764
Biological Process	GO:0006298	mismatch repair	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0006298	mismatch repair	RGD:620786	Msh2	ISS	Rat	RGD:1580655
Biological Process	GO:0006298	mismatch repair	FBgn0015546	spel1	ISS	Fly	FB:FBrf0105495
Biological Process	GO:0006298	mismatch repair	FBgn0015546	spel1	IMP	Fly	FB:FBrf0145154\|PMID:11815247
Biological Process	GO:0006298	mismatch repair	FBgn0015546	spel1	IMP	Fly	FB:FBrf0152211\|PMID:12150919
Biological Process	GO:0006298	mismatch repair	gene:3354686	MSH2	IMP	Tair	TAIR:Publication:501710568\|PMID:12970498
Biological Process	GO:0006298	mismatch repair	S000005450	MSH2	IMP	Yeast	SGD_REF:S000046828\|PMID:10523644
Biological Process	GO:0006298	mismatch repair	S000005450	MSH2	IMP	Yeast	SGD_REF:S000053177\|PMID:9520271
Biological Process	GO:0006298	mismatch repair	ZDB-GENE-040426-2932	msh2	ISS	Zfin	ZFIN:ZDB-PUB-041021-3\|PMID:15488992
Biological Process	GO:0006312	mitotic recombination	S000005450	MSH2	IMP	Yeast	SGD_REF:S000051942\|PMID:8849883
Biological Process	GO:0045910	negative regulation of DNA recombination	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1351797\|PMID:10545954
Biological Process	GO:0045910	negative regulation of DNA recombination	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:74950\|PMID:7628020
Biological Process	GO:0045910	negative regulation of DNA recombination	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0045128	negative regulation of meiotic recombination	gene:3354686	MSH2	IMP	Tair	TAIR:Publication:501717997\|PMID:16311517
Biological Process	GO:0043524	negative regulation of neuron apoptosis	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:3640229\|PMID:16805809
Biological Process	GO:0043524	negative regulation of neuron apoptosis	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0006119	oxidative phosphorylation	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:3640229\|PMID:16805809
Biological Process	GO:0006119	oxidative phosphorylation	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0006301	postreplication repair	P43246	MSH2_HUMAN	IDA	Human	PMID:7923193
Biological Process	GO:0006301	postreplication repair	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:74950\|PMID:7628020
Biological Process	GO:0006301	postreplication repair	RGD:620786	Msh2	ISS	Rat	RGD:1600115
Biological Process	GO:0006301	postreplication repair	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0006301	postreplication repair	RGD:620786	Msh2	ISS	Rat	RGD:1580655
Biological Process	GO:0006164	purine nucleotide biosynthetic process	MGI:101816	Msh2	IDA	Mouse	MGI:MGI:60112\|PMID:8492116
Biological Process	GO:0000735	removal of nonhomologous ends	S000005450	MSH2	IGI	Yeast	SGD_REF:S000040358\|PMID:9256462
Biological Process	GO:0000735	removal of nonhomologous ends	S000005450	MSH2	IMP	Yeast	SGD_REF:S000046828\|PMID:10523644
Biological Process	GO:0000735	removal of nonhomologous ends	S000005450	MSH2	IMP	Yeast	SGD_REF:S000040358\|PMID:9256462
Biological Process	GO:0006974	response to DNA damage stimulus	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:2136562\|PMID:11429706
Biological Process	GO:0006974	response to DNA damage stimulus	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1334080\|PMID:10097137
Biological Process	GO:0006974	response to DNA damage stimulus	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1354621\|PMID:10720738
Biological Process	GO:0006974	response to DNA damage stimulus	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:3029112\|PMID:14744764
Biological Process	GO:0010224	response to UV-B	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:3487309\|PMID:15166087
Biological Process	GO:0010165	response to X-ray	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:2667543\|PMID:12687013
Biological Process	GO:0010165	response to X-ray	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:3641481\|PMID:9607916
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	MGI:101816	Msh2	IGI	Mouse	MGI:MGI:3513244\|PMID:15494304
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1275866\|PMID:9697842
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:1275867\|PMID:9697843
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:2679186\|PMID:14568978
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0016447	somatic recombination of immunoglobulin gene segments	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:3581477\|PMID:15955838
Biological Process	GO:0016447	somatic recombination of immunoglobulin gene segments	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:3582380\|PMID:14563316
Biological Process	GO:0016447	somatic recombination of immunoglobulin gene segments	MGI:101816	Msh2	IGI	Mouse	MGI:MGI:3513244\|PMID:15494304
Biological Process	GO:0016447	somatic recombination of immunoglobulin gene segments	MGI:101816	Msh2	IMP	Mouse	MGI:MGI:2679186\|PMID:14568978
Biological Process	GO:0016447	somatic recombination of immunoglobulin gene segments	RGD:620786	Msh2	ISS	Rat	RGD:1580654
Biological Process	GO:0002204	somatic recombination of immunoglobulin genes during immune response	MGI:101816	Msh2	IGI	Mouse	MGI:MGI:2662086\|PMID:12743174

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)