Compare GO annotations for HomoloGene:21010 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0003779	actin binding	RGD:3590	Rock2	ISS	Rat	RGD:1580654
Molecular Function	GO:0005524	ATP binding	WB:WP:CE08098	LET-502	ISS	Worm	WB:WBPaper00002726\|PMID:9042856
Molecular Function	GO:0019992	diacylglycerol binding	FBgn0026181	rok	ISS	Fly	FB:FBrf0105495
Molecular Function	GO:0051020	GTPase binding	FBgn0026181	rok	IPI	Fly	FB:FBrf0135688\|PMID:11301004
Molecular Function	GO:0005515	protein binding	O75116	ROCK2_HUMAN	IPI	Human	PMID:17353931
Molecular Function	GO:0005515	protein binding	MGI:107926	Rock2	IPI	Mouse	MGI:MGI:3612236\|PMID:16365167
Molecular Function	GO:0005515	protein binding	RGD:3590	Rock2	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	FBgn0026181	rok	IPI	Fly	FB:FBrf0111979\|PMID:10570971
Molecular Function	GO:0004674	protein serine/threonine kinase activity	RGD:3590	Rock2	ISS	Rat	RGD:1580655
Molecular Function	GO:0004674	protein serine/threonine kinase activity	FBgn0026181	rok	ISS	Fly	FB:FBrf0105495
Molecular Function	GO:0004674	protein serine/threonine kinase activity	FBgn0026181	rok	ISS	Fly	FB:FBrf0107487
Molecular Function	GO:0004674	protein serine/threonine kinase activity	FBgn0026181	rok	IDA	Fly	FB:FBrf0111979\|PMID:10570971
Molecular Function	GO:0004674	protein serine/threonine kinase activity	FBgn0026181	rok	ISS	Fly	FB:FBrf0111979\|PMID:10570971
Molecular Function	GO:0004674	protein serine/threonine kinase activity	FBgn0026181	rok	ISS	Fly	FB:FBrf0126475
Molecular Function	GO:0004674	protein serine/threonine kinase activity	FBgn0026181	rok	IDA	Fly	FB:FBrf0135688\|PMID:11301004
Molecular Function	GO:0004674	protein serine/threonine kinase activity	WB:WP:CE08098	LET-502	ISS	Worm	WB:WBPaper00002726\|PMID:9042856
Molecular Function	GO:0005198	structural molecule activity	RGD:3590	Rock2	ISS	Rat	RGD:1580655
Cellular Component	GO:0015629	actin cytoskeleton	RGD:3590	Rock2	ISS	Rat	RGD:1580655
Cellular Component	GO:0005913	cell-cell adherens junction	WB:WP:CE08098	LET-502	IDA	Worm	WB:WBPaper00006149\|PMID:14522875
Cellular Component	GO:0043292	contractile fiber	WB:WP:CE08098	LET-502	IDA	Worm	WB:WBPaper00006149\|PMID:14522875
Cellular Component	GO:0005737	cytoplasm	WB:WP:CE08098	LET-502	IDA	Worm	WB:WBPaper00006149\|PMID:14522875
Cellular Component	GO:0005622	intracellular	RGD:3590	Rock2	ISS	Rat	RGD:1580654
Cellular Component	GO:0005634	nucleus	WB:WP:CE08098	LET-502	IDA	Worm	WB:WBPaper00003517\|PMID:10208747
Biological Process	GO:0030036	actin cytoskeleton organization and biogenesis	MGI:107926	Rock2	IGI	Mouse	MGI:MGI:3610718\|PMID:16249236
Biological Process	GO:0008150	biological_process	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0008150	biological_process	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0016477	cell migration	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00026774\|PMID:16170304
Biological Process	GO:0016477	cell migration	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00004959\|PMID:11687661
Biological Process	GO:0040002	collagen and cuticulin-based cuticle development	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0040002	collagen and cuticulin-based cuticle development	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0000910	cytokinesis	RGD:3590	Rock2	ISS	Rat	RGD:1580655
Biological Process	GO:0000910	cytokinesis	FBgn0026181	rok	IMP	Fly	FB:FBrf0180064\|PMID:15380073
Biological Process	GO:0000910	cytokinesis	FBgn0026181	rok	IMP	Fly	FB:FBrf0190018\|PMID:16488869
Biological Process	GO:0009790	embryonic development	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0009790	embryonic development	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00002726\|PMID:9042856
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00005318\|PMID:12006612
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00025054\|PMID:15791247
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00027756\|PMID:16845399
Biological Process	GO:0001737	establishment of imaginal disc-derived wing hair orientation	FBgn0026181	rok	IMP	Fly	FB:FBrf0135688\|PMID:11301004
Biological Process	GO:0042067	establishment of ommatidial polarity	FBgn0026181	rok	IMP	Fly	FB:FBrf0135688\|PMID:11301004
Biological Process	GO:0001703	gastrulation with mouth forming first	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0040007	growth	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0035317	imaginal disc-derived wing hair organization and biogenesis	FBgn0026181	rok	IGI	Fly	FB:FBrf0135688\|PMID:11301004
Biological Process	GO:0035317	imaginal disc-derived wing hair organization and biogenesis	FBgn0026181	rok	IMP	Fly	FB:FBrf0135688\|PMID:11301004
Biological Process	GO:0002119	larval development (sensu Nematoda)	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0002119	larval development (sensu Nematoda)	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0007067	mitosis	FBgn0026181	rok	IMP	Fly	FB:FBrf0190018\|PMID:16488869
Biological Process	GO:0000092	mitotic anaphase B	FBgn0026181	rok	IMP	Fly	FB:FBrf0190018\|PMID:16488869
Biological Process	GO:0000022	mitotic spindle elongation	FBgn0026181	rok	IMP	Fly	FB:FBrf0190018\|PMID:16488869
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	FBgn0026181	rok	IMP	Fly	FB:FBrf0190283\|PMID:16123312
Biological Process	GO:0006936	muscle contraction	RGD:3590	Rock2	ISS	Rat	RGD:1580655
Biological Process	GO:0040018	positive regulation of body size	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0040018	positive regulation of body size	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0040032	post-embryonic body morphogenesis	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0006468	protein amino acid phosphorylation	RGD:3590	Rock2	ISS	Rat	RGD:1580655
Biological Process	GO:0006468	protein amino acid phosphorylation	FBgn0026181	rok	ISS	Fly	FB:FBrf0107487
Biological Process	GO:0006468	protein amino acid phosphorylation	WB:WP:CE08098	LET-502	ISS	Worm	WB:WBPaper00002726\|PMID:9042856
Biological Process	GO:0032231	regulation of actin filament bundle formation	FBgn0026181	rok	IGI	Fly	FB:FBrf0135688\|PMID:11301004
Biological Process	GO:0032231	regulation of actin filament bundle formation	FBgn0026181	rok	IMP	Fly	FB:FBrf0135688\|PMID:11301004
Biological Process	GO:0050770	regulation of axonogenesis	FBgn0026181	rok	IGI	Fly	FB:FBrf0180582\|PMID:15572110
Biological Process	GO:0008360	regulation of cell shape	FBgn0026181	rok	IMP	Fly	FB:FBrf0190283\|PMID:16123312
Biological Process	GO:0008360	regulation of cell shape	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00002726\|PMID:9042856
Biological Process	GO:0001932	regulation of protein amino acid phosphorylation	FBgn0026181	rok	IMP	Fly	FB:FBrf0135688\|PMID:11301004
Biological Process	GO:0000003	reproduction	WBGene00002694	let-502	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0007266	Rho protein signal transduction	FBgn0026181	rok	IPI	Fly	FB:FBrf0111979\|PMID:10570971
Biological Process	GO:0007165	signal transduction	RGD:3590	Rock2	ISS	Rat	RGD:1580654

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)