Compare GO annotations for HomoloGene:21033 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0005131	growth hormone receptor binding	RGD:2939	Jak2	IPI	Rat	RGD:1624962\|PMID:11244571
Molecular Function	GO:0004718	Janus kinase activity	MGI:96629	Jak2	IDA	Mouse	MGI:MGI:2386424\|PMID:12147240
Molecular Function	GO:0004718	Janus kinase activity	MGI:96629	Jak2	IMP	Mouse	MGI:MGI:3036919\|PMID:15012602
Molecular Function	GO:0004718	Janus kinase activity	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Molecular Function	GO:0004718	Janus kinase activity	FBgn0004864	hop	ISS	Fly	FB:FBrf0068418\|PMID:8314084
Molecular Function	GO:0004718	Janus kinase activity	FBgn0004864	hop	ISS	Fly	FB:FBrf0105495
Molecular Function	GO:0005515	protein binding	MGI:96629	Jak2	IPI	Mouse	MGI:MGI:3703676\|PMID:12388746
Molecular Function	GO:0005515	protein binding	MGI:96629	Jak2	IPI	Mouse	MGI:MGI:83970\|PMID:8943354
Molecular Function	GO:0005515	protein binding	MGI:96629	Jak2	IPI	Mouse	MGI:MGI:1098502\|PMID:9202126
Molecular Function	GO:0005515	protein binding	MGI:96629	Jak2	IPI	Mouse	MGI:MGI:1859033\|PMID:10872802
Molecular Function	GO:0005515	protein binding	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Molecular Function	GO:0004674	protein serine/threonine kinase activity	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Molecular Function	GO:0004713	protein-tyrosine kinase activity	MGI:96629	Jak2	IDA	Mouse	MGI:MGI:1859033\|PMID:10872802
Molecular Function	GO:0004713	protein-tyrosine kinase activity	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Molecular Function	GO:0004713	protein-tyrosine kinase activity	RGD:2939	Jak2	ISS	Rat	RGD:1580655
Molecular Function	GO:0005102	receptor binding	O60674	JAK2_HUMAN	IPI	Human	PMID:11201744
Molecular Function	GO:0005102	receptor binding	RGD:2939	Jak2	ISS	Rat	RGD:1580655
Molecular Function	GO:0042169	SH2 domain binding	O60674	JAK2_HUMAN	IPI	Human	PMID:9727029
Molecular Function	GO:0042169	SH2 domain binding	RGD:2939	Jak2	ISS	Rat	RGD:1580655
Molecular Function	GO:0051082	unfolded protein binding	FBgn0024352	Hop	ISS	Fly	FB:FBrf0105495
Cellular Component	GO:0005737	cytoplasm	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Cellular Component	GO:0045121	lipid raft	MGI:96629	Jak2	IDA	Mouse	MGI:MGI:3703676\|PMID:12388746
Biological Process	GO:0006915	apoptosis	MGI:96629	Jak2	IDA	Mouse	MGI:MGI:2386424\|PMID:12147240
Biological Process	GO:0006915	apoptosis	MGI:96629	Jak2	IMP	Mouse	MGI:MGI:3036919\|PMID:15012602
Biological Process	GO:0006915	apoptosis	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Biological Process	GO:0007350	blastoderm segmentation	FBgn0004864	hop	IMP	Fly	FB:FBrf0155684\|PMID:12586062
Biological Process	GO:0007298	border follicle cell migration	FBgn0004864	hop	IMP	Fly	FB:FBrf0155683\|PMID:12586061
Biological Process	GO:0030154	cell differentiation	MGI:96629	Jak2	IMP	Mouse	MGI:MGI:2178483\|PMID:11821424
Biological Process	GO:0030154	cell differentiation	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Biological Process	GO:0006928	cell motility	RGD:2939	Jak2	ISS	Rat	RGD:1580655
Biological Process	GO:0008283	cell proliferation	FBgn0004864	hop	IMP	Fly	FB:FBrf0068418\|PMID:8314084
Biological Process	GO:0048749	compound eye development	FBgn0004864	hop	IMP	Fly	FB:FBrf0111419\|PMID:10479459
Biological Process	GO:0048749	compound eye development	FBgn0004864	hop	IMP	Fly	FB:FBrf0141375\|PMID:11746233
Biological Process	GO:0001751	compound eye photoreceptor cell differentiation	FBgn0004864	hop	IMP	Fly	FB:FBrf0111419\|PMID:10479459
Biological Process	GO:0019221	cytokine and chemokine mediated signaling pathway	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Biological Process	GO:0051607	defense response to virus	FBgn0004864	hop	IMP	Fly	FB:FBrf0188155\|PMID:16086017
Biological Process	GO:0007167	enzyme linked receptor protein signaling pathway	MGI:96629	Jak2	IDA	Mouse	MGI:MGI:67395\|PMID:8022486
Biological Process	GO:0045317	equator specification	FBgn0004864	hop	IMP	Fly	FB:FBrf0111419\|PMID:10479459
Biological Process	GO:0045317	equator specification	FBgn0004864	hop	IMP	Fly	FB:FBrf0141375\|PMID:11746233
Biological Process	GO:0042067	establishment of ommatidial polarity	FBgn0004864	hop	IMP	Fly	FB:FBrf0111419\|PMID:10479459
Biological Process	GO:0042386	hemocyte differentiation	FBgn0004864	hop	IMP	Fly	FB:FBrf0147160
Biological Process	GO:0007442	hindgut morphogenesis	FBgn0004864	hop	IMP	Fly	FB:FBrf0151948\|PMID:12441298
Biological Process	GO:0007442	hindgut morphogenesis	FBgn0004864	hop	IMP	Fly	FB:FBrf0167843\|PMID:14654218
Biological Process	GO:0007242	intracellular signaling cascade	RGD:2939	Jak2	ISS	Rat	RGD:1580655
Biological Process	GO:0007259	JAK-STAT cascade	MGI:96629	Jak2	IMP	Mouse	MGI:MGI:2178483\|PMID:11821424
Biological Process	GO:0007259	JAK-STAT cascade	MGI:96629	Jak2	IDA	Mouse	MGI:MGI:2386424\|PMID:12147240
Biological Process	GO:0007259	JAK-STAT cascade	MGI:96629	Jak2	IMP	Mouse	MGI:MGI:3052366\|PMID:15354294
Biological Process	GO:0007259	JAK-STAT cascade	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Biological Process	GO:0007259	JAK-STAT cascade	RGD:2939	Jak2	ISS	Rat	RGD:1580655
Biological Process	GO:0007259	JAK-STAT cascade	RGD:2939	Jak2	IDA	Rat	RGD:1624963\|PMID:11064147
Biological Process	GO:0007259	JAK-STAT cascade	FBgn0004864	hop	IGI	Fly	FB:FBrf0086463\|PMID:8608595
Biological Process	GO:0007259	JAK-STAT cascade	FBgn0004864	hop	ISS	Fly	FB:FBrf0086463\|PMID:8608595
Biological Process	GO:0007498	mesoderm development	RGD:2939	Jak2	ISS	Rat	RGD:1580655
Biological Process	GO:0030099	myeloid cell differentiation	MGI:96629	Jak2	IMP	Mouse	MGI:MGI:3052366\|PMID:15354294
Biological Process	GO:0030099	myeloid cell differentiation	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Biological Process	GO:0008285	negative regulation of cell proliferation	MGI:96629	Jak2	IMP	Mouse	MGI:MGI:2178483\|PMID:11821424
Biological Process	GO:0008285	negative regulation of cell proliferation	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Biological Process	GO:0007399	nervous system development	FBgn0004864	hop	IMP	Fly	FB:FBrf0167843\|PMID:14654218
Biological Process	GO:0016318	ommatidial rotation	FBgn0004864	hop	IMP	Fly	FB:FBrf0141375\|PMID:11746233
Biological Process	GO:0007424	open tracheal system development	FBgn0004864	hop	IMP	Fly	FB:FBrf0155684\|PMID:12586062
Biological Process	GO:0007424	open tracheal system development	FBgn0004864	hop	IMP	Fly	FB:FBrf0167843\|PMID:14654218
Biological Process	GO:0030707	ovarian follicle cell development	FBgn0004864	hop	IMP	Fly	FB:FBrf0155683\|PMID:12586061
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	MGI:96629	Jak2	IDA	Mouse	MGI:MGI:1859033\|PMID:10872802
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Biological Process	GO:0007365	periodic partitioning	FBgn0004864	hop	IMP	Fly	FB:FBrf0068418\|PMID:8314084
Biological Process	GO:0046427	positive regulation of JAK-STAT cascade	ZDB-GENE-980526-481	jak2a	IDA	Zfin	ZFIN:ZDB-PUB-060210-15\|PMID:16459186
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	ZDB-GENE-980526-481	jak2a	IDA	Zfin	ZFIN:ZDB-PUB-060210-15\|PMID:16459186
Biological Process	GO:0007538	primary sex determination	FBgn0004864	hop	IMP	Fly	FB:FBrf0128151\|PMID:10882142
Biological Process	GO:0006468	protein amino acid phosphorylation	RGD:2939	Jak2	ISS	Rat	RGD:1580655
Biological Process	GO:0006457	protein folding	FBgn0024352	Hop	ISS	Fly	FB:FBrf0105495
Biological Process	GO:0007243	protein kinase cascade	MGI:96629	Jak2	IDA	Mouse	MGI:MGI:67395\|PMID:8022486
Biological Process	GO:0045610	regulation of hemocyte differentiation	FBgn0004864	hop	IMP	Fly	FB:FBrf0180639\|PMID:15381778
Biological Process	GO:0000074	regulation of progression through cell cycle	RGD:2939	Jak2	ISS	Rat	RGD:1580655
Biological Process	GO:0007262	STAT protein nuclear translocation	MGI:96629	Jak2	IDA	Mouse	MGI:MGI:2386424\|PMID:12147240
Biological Process	GO:0007262	STAT protein nuclear translocation	RGD:2939	Jak2	ISS	Rat	RGD:1580654
Biological Process	GO:0019827	stem cell maintenance	FBgn0004864	hop	IMP	Fly	FB:FBrf0141753\|PMID:11752574
Biological Process	GO:0007260	tyrosine phosphorylation of STAT protein	MGI:96629	Jak2	IMP	Mouse	MGI:MGI:2178483\|PMID:11821424
Biological Process	GO:0007260	tyrosine phosphorylation of STAT protein	RGD:2939	Jak2	ISS	Rat	RGD:1580654

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)