Compare GO annotations for HomoloGene:2122 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	RGD:3447	Ptpn11	ISS	Rat	RGD:1580654
Molecular Function	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	RGD:3447	Ptpn11	ISS	Rat	RGD:1580655
Molecular Function	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	FBgn0000382	csw	ISS	Fly	FB:FBrf0055550\|PMID:1638629
Molecular Function	GO:0043274	phospholipase binding	RGD:3447	Ptpn11	IDA	Rat	RGD:1601575\|PMID:16814162
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	MGI:99511	Ptpn11	IMP	Mouse	MGI:MGI:3047525\|PMID:15273746
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	RGD:3447	Ptpn11	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	Q96I26	Q96I26_HUMAN	IPI	Human	PMID:10209036
Molecular Function	GO:0005515	protein binding	Q06124	PTN11_HUMAN	IPI	Human	PMID:9792637
Molecular Function	GO:0005515	protein binding	Q06124	PTN11_HUMAN	IPI	Human	PMID:9658397
Molecular Function	GO:0005515	protein binding	MGI:99511	Ptpn11	IPI	Mouse	MGI:MGI:2670845\|PMID:12893283
Molecular Function	GO:0005515	protein binding	MGI:99511	Ptpn11	ISS	Mouse	MGI:MGI:2662669\|PMID:12611902
Molecular Function	GO:0005515	protein binding	MGI:99511	Ptpn11	IPI	Mouse	MGI:MGI:2177910\|PMID:11895767
Molecular Function	GO:0005515	protein binding	MGI:99511	Ptpn11	IPI	Mouse	MGI:MGI:2664443\|PMID:12808090
Molecular Function	GO:0005515	protein binding	MGI:99511	Ptpn11	IPI	Mouse	MGI:MGI:3047525\|PMID:15273746
Molecular Function	GO:0005515	protein binding	MGI:99511	Ptpn11	IPI	Mouse	MGI:MGI:3521631\|PMID:15568026
Molecular Function	GO:0005515	protein binding	RGD:3447	Ptpn11	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	RGD:3447	Ptpn11	ISS	Rat	RGD:1580655
Molecular Function	GO:0005515	protein binding	RGD:3447	Ptpn11	ISS	Rat	RGD:1625039\|PMID:12177051
Molecular Function	GO:0005515	protein binding	RGD:3447	Ptpn11	IDA	Rat	RGD:1601572\|PMID:15115663
Molecular Function	GO:0005515	protein binding	RGD:3447	Ptpn11	IDA	Rat	RGD:1601574\|PMID:16690621
Molecular Function	GO:0005515	protein binding	FBgn0000382	csw	IPI	Fly	FB:FBrf0102661\|PMID:9582352
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	RGD:3447	Ptpn11	IDA	Rat	RGD:729786\|PMID:7512964
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	RGD:3447	Ptpn11	IDA	Rat	RGD:1581313\|PMID:15272025
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	RGD:3447	Ptpn11	IDA	Rat	RGD:1601573\|PMID:15378208
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	FBgn0000382	csw	IDA	Fly	FB:FBrf0088202\|PMID:8681384
Cellular Component	GO:0030054	cell junction	MGI:99511	Ptpn11	ISS	Mouse	MGI:MGI:2662669\|PMID:12611902
Cellular Component	GO:0005624	membrane fraction	MGI:99511	Ptpn11	ISS	Mouse	MGI:MGI:2662669\|PMID:12611902
Cellular Component	GO:0005739	mitochondrion	RGD:3447	Ptpn11	IDA	Rat	RGD:1601573\|PMID:15378208
Cellular Component	GO:0005625	soluble fraction	RGD:3447	Ptpn11	IDA	Rat	RGD:1601572\|PMID:15115663
Cellular Component	GO:0001725	stress fiber	MGI:99511	Ptpn11	ISS	Mouse	MGI:MGI:2662669\|PMID:12611902
Biological Process	GO:0000187	activation of MAPK activity	MGI:99511	Ptpn11	IMP	Mouse	MGI:MGI:2679752\|PMID:12937170
Biological Process	GO:0000187	activation of MAPK activity	MGI:99511	Ptpn11	IMP	Mouse	MGI:MGI:3047525\|PMID:15273746
Biological Process	GO:0000187	activation of MAPK activity	RGD:3447	Ptpn11	ISS	Rat	RGD:1580654
Biological Process	GO:0007409	axonogenesis	MGI:99511	Ptpn11	IMP	Mouse	MGI:MGI:2447085\|PMID:12482708
Biological Process	GO:0007409	axonogenesis	RGD:3447	Ptpn11	ISS	Rat	RGD:1580654
Biological Process	GO:0000077	DNA damage checkpoint	MGI:99511	Ptpn11	IMP	Mouse	MGI:MGI:2679752\|PMID:12937170
Biological Process	GO:0000077	DNA damage checkpoint	RGD:3447	Ptpn11	ISS	Rat	RGD:1580654
Biological Process	GO:0008069	dorsal/ventral axis determination, ovarian follicular epithelium	FBgn0000382	csw	IMP	Fly	FB:FBrf0090739\|PMID:8948575
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00004214	ptp-2	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	FBgn0000382	csw	IGI	Fly	FB:FBrf0053392\|PMID:1934068
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	FBgn0000382	csw	IGI	Fly	FB:FBrf0090739\|PMID:8948575
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	FBgn0000382	csw	IMP	Fly	FB:FBrf0090739\|PMID:8948575
Biological Process	GO:0007427	epithelial cell migration, open tracheal system	FBgn0000382	csw	IMP	Fly	FB:FBrf0090739\|PMID:8948575
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	FBgn0000382	csw	IMP	Fly	FB:FBrf0090739\|PMID:8948575
Biological Process	GO:0007444	imaginal disc development	FBgn0000382	csw	IMP	Fly	FB:FBrf0090739\|PMID:8948575
Biological Process	GO:0002119	larval development (sensu Nematoda)	WBGene00004214	ptp-2	IGI	Worm	WB:WBPaper00003006\|PMID:9472025
Biological Process	GO:0007626	locomotory behavior	WBGene00004214	ptp-2	IMP	Worm	WB:WBPaper00005599\|PMID:12445391
Biological Process	GO:0007498	mesoderm development	FBgn0000382	csw	IMP	Fly	FB:FBrf0141548\|PMID:11729154
Biological Process	GO:0007517	muscle development	WBGene00004214	ptp-2	IMP	Worm	WB:WBPaper00027119\|PMID:16495308
Biological Process	GO:0048011	nerve growth factor receptor signaling pathway	MGI:99511	Ptpn11	IMP	Mouse	MGI:MGI:2447085\|PMID:12482708
Biological Process	GO:0048011	nerve growth factor receptor signaling pathway	RGD:3447	Ptpn11	ISS	Rat	RGD:1580654
Biological Process	GO:0048477	oogenesis	WBGene00004214	ptp-2	IMP	Worm	WB:WBPaper00003006\|PMID:9472025
Biological Process	GO:0007424	open tracheal system development	FBgn0000382	csw	IGI	Fly	FB:FBrf0190302\|PMID:16481357
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	WBGene00004214	ptp-2	IGI	Worm	WB:WBPaper00003006\|PMID:9472025
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	WBGene00004214	ptp-2	IGI	Worm	WB:WBPaper00003006\|PMID:9472025
Biological Process	GO:0040026	positive regulation of vulval development (sensu Nematoda)	WBGene00004214	ptp-2	IGI	Worm	WB:WBPaper00003006\|PMID:9472025
Biological Process	GO:0006470	protein amino acid dephosphorylation	RGD:3447	Ptpn11	IDA	Rat	RGD:1581313\|PMID:15272025
Biological Process	GO:0006470	protein amino acid dephosphorylation	FBgn0000382	csw	IDA	Fly	FB:FBrf0088202\|PMID:8681384
Biological Process	GO:0007465	R7 cell fate commitment	FBgn0000382	csw	IGI	Fly	FB:FBrf0053392\|PMID:1934068
Biological Process	GO:0031344	regulation of cell projection organization and biogenesis	WBGene00004214	ptp-2	IMP	Worm	WB:WBPaper00027119\|PMID:16495308
Biological Process	GO:0045314	regulation of compound eye photoreceptor development	FBgn0000382	csw	IMP	Fly	FB:FBrf0190302\|PMID:16481357
Biological Process	GO:0046825	regulation of protein export from nucleus	MGI:99511	Ptpn11	IMP	Mouse	MGI:MGI:2679752\|PMID:12937170
Biological Process	GO:0046825	regulation of protein export from nucleus	RGD:3447	Ptpn11	ISS	Rat	RGD:1580654
Biological Process	GO:0007165	signal transduction	RGD:3447	Ptpn11	ISS	Rat	RGD:1580654
Biological Process	GO:0007362	terminal region determination	FBgn0000382	csw	IMP	Fly	FB:FBrf0055550\|PMID:1638629
Biological Process	GO:0008293	torso signaling pathway	FBgn0000382	csw	IGI	Fly	FB:FBrf0055550\|PMID:1638629
Biological Process	GO:0007418	ventral midline development	FBgn0000382	csw	IMP	Fly	FB:FBrf0090739\|PMID:8948575

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)