Compare GO annotations for HomoloGene:2180 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	RGD:3169	Nf2	IPI	Rat	RGD:1599271\|PMID:15659388
Molecular Function	GO:0008092	cytoskeletal protein binding	FBgn0086384	Mer	ISS	Fly	FB:FBrf0132100\|PMID:10908588
Molecular Function	GO:0005178	integrin binding	RGD:3169	Nf2	IPI	Rat	RGD:1599274\|PMID:9858254
Molecular Function	GO:0005515	protein binding	MGI:97307	Nf2	IPI	Mouse	MGI:MGI:2656687\|PMID:12695331
Molecular Function	GO:0005515	protein binding	MGI:97307	Nf2	IPI	Mouse	MGI:MGI:2679135\|PMID:14580336
Molecular Function	GO:0005515	protein binding	MGI:97307	Nf2	IPI	Mouse	MGI:MGI:3613261\|PMID:16405865
Molecular Function	GO:0005515	protein binding	RGD:3169	Nf2	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	FBgn0086384	Mer	IPI	Fly	FB:FBrf0088536\|PMID:8666669
Molecular Function	GO:0019904	protein domain specific binding	RGD:3169	Nf2	IPI	Rat	RGD:1599273\|PMID:11316791
Cellular Component	GO:0005912	adherens junction	MGI:97307	Nf2	IMP	Mouse	MGI:MGI:2656687\|PMID:12695331
Cellular Component	GO:0005912	adherens junction	RGD:3169	Nf2	ISS	Rat	RGD:1580654
Cellular Component	GO:0005912	adherens junction	FBgn0086384	Mer	IDA	Fly	FB:FBrf0088536\|PMID:8666669
Cellular Component	GO:0032154	cleavage furrow	MGI:97307	Nf2	IDA	Mouse	MGI:MGI:1197341\|PMID:9631655
Cellular Component	GO:0005737	cytoplasm	P35240	MERL_HUMAN	IDA	Human	PMID:9537418
Cellular Component	GO:0005737	cytoplasm	MGI:97307	Nf2	IDA	Mouse	MGI:MGI:79149\|PMID:8547603
Cellular Component	GO:0005737	cytoplasm	MGI:97307	Nf2	IDA	Mouse	MGI:MGI:3047165\|PMID:15133494
Cellular Component	GO:0005737	cytoplasm	RGD:3169	Nf2	IDA	Rat	RGD:1599271\|PMID:15659388
Cellular Component	GO:0005737	cytoplasm	FBgn0086384	Mer	IDA	Fly	FB:FBrf0088536\|PMID:8666669
Cellular Component	GO:0005737	cytoplasm	FBgn0086384	Mer	IDA	Fly	FB:FBrf0091300\|PMID:9012516
Cellular Component	GO:0005737	cytoplasm	FBgn0086384	Mer	IDA	Fly	FB:FBrf0102961\|PMID:9647651
Cellular Component	GO:0005856	cytoskeleton	RGD:3169	Nf2	ISS	Rat	RGD:1580655
Cellular Component	GO:0005769	early endosome	P35240	MERL_HUMAN	IDA	Human	PMID:10861283
Cellular Component	GO:0030175	filopodium	MGI:97307	Nf2	IDA	Mouse	MGI:MGI:1202233\|PMID:9563848
Cellular Component	GO:0045169	fusome	FBgn0086384	Mer	IDA	Fly	FB:FBrf0091300\|PMID:9012516
Cellular Component	GO:0005626	insoluble fraction	RGD:3169	Nf2	IDA	Rat	RGD:1599274\|PMID:9858254
Cellular Component	GO:0030027	lamellipodium	MGI:97307	Nf2	IDA	Mouse	MGI:MGI:1202233\|PMID:9563848
Cellular Component	GO:0016020	membrane	FBgn0086384	Mer	IDA	Fly	FB:FBrf0102961\|PMID:9647651
Cellular Component	GO:0005730	nucleolus	P35240	MERL_HUMAN	IDA	Human	PMID:9537418
Cellular Component	GO:0005634	nucleus	P35240	MERL_HUMAN	IDA	Human	PMID:10401006
Cellular Component	GO:0005634	nucleus	MGI:97307	Nf2	IDA	Mouse	MGI:MGI:3047165\|PMID:15133494
Cellular Component	GO:0005634	nucleus	RGD:3169	Nf2	ISS	Rat	RGD:1580655
Cellular Component	GO:0048471	perinuclear region of cytoplasm	P35240	MERL_HUMAN	IDA	Human	PMID:17210637
Cellular Component	GO:0048471	perinuclear region of cytoplasm	RGD:3169	Nf2	IDA	Rat	RGD:1599274\|PMID:9858254
Cellular Component	GO:0005886	plasma membrane	P35240	MERL_HUMAN	IDA	Human	PMID:10401006
Cellular Component	GO:0005886	plasma membrane	RGD:3169	Nf2	ISS	Rat	RGD:1580655
Cellular Component	GO:0005886	plasma membrane	RGD:3169	Nf2	IDA	Rat	RGD:1599274\|PMID:9858254
Cellular Component	GO:0005886	plasma membrane	FBgn0086384	Mer	IDA	Fly	FB:FBrf0091300\|PMID:9012516
Cellular Component	GO:0043234	protein complex	RGD:3169	Nf2	IDA	Rat	RGD:1599273\|PMID:11316791
Cellular Component	GO:0001726	ruffle	MGI:97307	Nf2	IDA	Mouse	MGI:MGI:1202233\|PMID:9563848
Cellular Component	GO:0005625	soluble fraction	RGD:3169	Nf2	IDA	Rat	RGD:1599274\|PMID:9858254
Biological Process	GO:0030036	actin cytoskeleton organization and biogenesis	P35240	MERL_HUMAN	IMP	Human	PMID:9537418
Biological Process	GO:0009798	axis specification	FBgn0086384	Mer	IMP	Fly	FB:FBrf0134575\|PMID:11171392
Biological Process	GO:0007267	cell-cell signaling	FBgn0086384	Mer	IEP	Fly	FB:FBrf0088536\|PMID:8666669
Biological Process	GO:0007398	ectoderm development	MGI:97307	Nf2	IMP	Mouse	MGI:MGI:707944\|PMID:9171370
Biological Process	GO:0006897	endocytosis	FBgn0086384	Mer	IEP	Fly	FB:FBrf0088536\|PMID:8666669
Biological Process	GO:0045216	intercellular junction assembly and maintenance	MGI:97307	Nf2	IMP	Mouse	MGI:MGI:2656687\|PMID:12695331
Biological Process	GO:0045216	intercellular junction assembly and maintenance	RGD:3169	Nf2	ISS	Rat	RGD:1580654
Biological Process	GO:0001707	mesoderm formation	MGI:97307	Nf2	IMP	Mouse	MGI:MGI:707944\|PMID:9171370
Biological Process	GO:0030308	negative regulation of cell growth	RGD:3169	Nf2	IDA	Rat	RGD:1599273\|PMID:11316791
Biological Process	GO:0008285	negative regulation of cell proliferation	P35240	MERL_HUMAN	IMP	Human	PMID:17210637
Biological Process	GO:0008285	negative regulation of cell proliferation	P35240	MERL_HUMAN	IDA	Human	PMID:12444102
Biological Process	GO:0008285	negative regulation of cell proliferation	MGI:97307	Nf2	IMP	Mouse	MGI:MGI:1203257\|PMID:9553042
Biological Process	GO:0008285	negative regulation of cell proliferation	MGI:97307	Nf2	IMP	Mouse	MGI:MGI:1860693\|PMID:10887156
Biological Process	GO:0008285	negative regulation of cell proliferation	RGD:3169	Nf2	ISS	Rat	RGD:1580655
Biological Process	GO:0008156	negative regulation of DNA replication	P35240	MERL_HUMAN	IMP	Human	PMID:17210637
Biological Process	GO:0046426	negative regulation of JAK-STAT cascade	P35240	MERL_HUMAN	IDA	Human	PMID:12444102
Biological Process	GO:0043409	negative regulation of MAPKKK cascade	MGI:97307	Nf2	IMP	Mouse	MGI:MGI:3613261\|PMID:16405865
Biological Process	GO:0006469	negative regulation of protein kinase activity	MGI:97307	Nf2	IDA	Mouse	MGI:MGI:2679135\|PMID:14580336
Biological Process	GO:0006469	negative regulation of protein kinase activity	MGI:97307	Nf2	IMP	Mouse	MGI:MGI:3613261\|PMID:16405865
Biological Process	GO:0006469	negative regulation of protein kinase activity	RGD:3169	Nf2	ISS	Rat	RGD:1580654
Biological Process	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	P35240	MERL_HUMAN	IDA	Human	PMID:12444102
Biological Process	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	P35240	MERL_HUMAN	IDA	Human	PMID:12444102
Biological Process	GO:0042475	odontogenesis (sensu Vertebrata)	MGI:97307	Nf2	IMP	Mouse	MGI:MGI:1860693\|PMID:10887156
Biological Process	GO:0042048	olfactory behavior	FBgn0086384	Mer	IMP	Fly	FB:FBrf0192106\|PMID:17028343
Biological Process	GO:0019094	pole plasm mRNA localization	FBgn0086384	Mer	IMP	Fly	FB:FBrf0180506\|PMID:15385627
Biological Process	GO:0051496	positive regulation of stress fiber formation	P35240	MERL_HUMAN	IMP	Human	PMID:9537418
Biological Process	GO:0001558	regulation of cell growth	FBgn0086384	Mer	IEP	Fly	FB:FBrf0088536\|PMID:8666669
Biological Process	GO:0042127	regulation of cell proliferation	MGI:97307	Nf2	IMP	Mouse	MGI:MGI:2656687\|PMID:12695331
Biological Process	GO:0042127	regulation of cell proliferation	RGD:3169	Nf2	ISS	Rat	RGD:1580654
Biological Process	GO:0042127	regulation of cell proliferation	FBgn0086384	Mer	IMP	Fly	FB:FBrf0102961\|PMID:9647651
Biological Process	GO:0014010	Schwann cell proliferation	P35240	MERL_HUMAN	IMP	Human	PMID:17353411

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)