Compare GO annotations for HomoloGene:22742 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0005515	protein binding	Q9UHD2	TBK1_HUMAN	IPI	Human	PMID:16887178
Molecular Function	GO:0005515	protein binding	MGI:1929658	Tbk1	IPI	Mouse	MGI:MGI:1928254\|PMID:10581243
Molecular Function	GO:0005515	protein binding	FBgn0086657	ik2	IPI	Fly	FB:FBrf0194448\|PMID:16887178
Molecular Function	GO:0004674	protein serine/threonine kinase activity	FBgn0086657	ik2	ISS	Fly	FB:FBrf0105495
Molecular Function	GO:0004871	signal transducer activity	Q9UHD2	TBK1_HUMAN	IEP	Human	PMID:12761501
Biological Process	GO:0007015	actin filament organization	FBgn0086657	ik2	IMP	Fly	FB:FBrf0193419\|PMID:16887350
Biological Process	GO:0008219	cell death	FBgn0086657	ik2	IMP	Fly	FB:FBrf0194448\|PMID:16887178
Biological Process	GO:0000902	cell morphogenesis	FBgn0086657	ik2	IMP	Fly	FB:FBrf0193419\|PMID:16887350
Biological Process	GO:0035160	maintenance of epithelial integrity, open tracheal system	FBgn0086657	ik2	IMP	Fly	FB:FBrf0193419\|PMID:16887350
Biological Process	GO:0043280	positive regulation of caspase activity	FBgn0086657	ik2	IMP	Fly	FB:FBrf0194448\|PMID:16887178
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	Q9UHD2	TBK1_HUMAN	IEP	Human	PMID:12761501

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)