Compare GO annotations for HomoloGene:22999 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	RGD:2927	Itgb1	ISS	Rat	RGD:1302874\|PMID:9633916
Molecular Function	GO:0042802	identical protein binding	P05556	ITB1_HUMAN	IPI	Human	PMID:14681217
Molecular Function	GO:0005178	integrin binding	MGI:96610	Itgb1	IPI	Mouse	MGI:MGI:79483\|PMID:8601592
Molecular Function	GO:0005178	integrin binding	RGD:2927	Itgb1	ISS	Rat	RGD:1580654
Molecular Function	GO:0005178	integrin binding	RGD:2927	Itgb1	IMP	Rat	RGD:1625131\|PMID:17118629
Molecular Function	GO:0042277	peptide binding	RGD:2927	Itgb1	IDA	Rat	RGD:1625134\|PMID:12639933
Molecular Function	GO:0005515	protein binding	MGI:96610	Itgb1	IPI	Mouse	MGI:MGI:2670471\|PMID:12904471
Molecular Function	GO:0005515	protein binding	MGI:96610	Itgb1	IPI	Mouse	MGI:MGI:2675140\|PMID:10613898
Molecular Function	GO:0005515	protein binding	MGI:96610	Itgb1	IPI	Mouse	MGI:MGI:3573989\|PMID:15723043
Molecular Function	GO:0005515	protein binding	RGD:2927	Itgb1	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	RGD:2927	Itgb1	IPI	Rat	RGD:1599274\|PMID:9858254
Molecular Function	GO:0005515	protein binding	RGD:2927	Itgb1	ISS	Rat	RGD:1600115
Molecular Function	GO:0046982	protein heterodimerization activity	RGD:2927	Itgb1	IMP	Rat	RGD:1625131\|PMID:17118629
Cellular Component	GO:0001669	acrosome	RGD:2927	Itgb1	IDA	Rat	RGD:1581320\|PMID:9202984
Cellular Component	GO:0005604	basement membrane	RGD:2927	Itgb1	IDA	Rat	RGD:1581320\|PMID:9202984
Cellular Component	GO:0009986	cell surface	WB:WP:CE01102	PAT-3	IDA	Worm	WB:WBPaper00002179\|PMID:7744961
Cellular Component	GO:0005737	cytoplasm	RGD:2927	Itgb1	ISS	Rat	RGD:1302874\|PMID:9633916
Cellular Component	GO:0005783	endoplasmic reticulum	Q8WUM6	Q8WUM6_HUMAN	IDA	Human	PMID:11256614
Cellular Component	GO:0005615	extracellular space	RGD:2927	Itgb1	ISS	Rat	RGD:1302874\|PMID:9633916
Cellular Component	GO:0005925	focal adhesion	RGD:2927	Itgb1	IDA	Rat	RGD:1625132\|PMID:17157995
Cellular Component	GO:0005925	focal adhesion	FBgn0004657	mys	ISS	Fly	FB:FBrf0129868\|PMID:10908592
Cellular Component	GO:0016021	integral to membrane	RGD:2927	Itgb1	ISS	Rat	RGD:1302874\|PMID:9633916
Cellular Component	GO:0008305	integrin complex	RGD:2927	Itgb1	ISS	Rat	RGD:1302874\|PMID:9633916
Cellular Component	GO:0008305	integrin complex	RGD:2927	Itgb1	IMP	Rat	RGD:1625131\|PMID:17118629
Cellular Component	GO:0008305	integrin complex	RGD:2927	Itgb1	IDA	Rat	RGD:1625132\|PMID:17157995
Cellular Component	GO:0008305	integrin complex	FBgn0004657	mys	ISS	Fly	FB:FBrf0129868\|PMID:10908592
Cellular Component	GO:0031252	leading edge	FBgn0004657	mys	IDA	Fly	FB:FBrf0184059\|PMID:15596544
Cellular Component	GO:0045121	lipid raft	RGD:2927	Itgb1	IDA	Rat	RGD:1625132\|PMID:17157995
Cellular Component	GO:0005624	membrane fraction	RGD:2927	Itgb1	IDA	Rat	RGD:1581320\|PMID:9202984
Cellular Component	GO:0005624	membrane fraction	RGD:2927	Itgb1	IDA	Rat	RGD:1625132\|PMID:17157995
Cellular Component	GO:0005886	plasma membrane	MGI:96610	Itgb1	IDA	Mouse	MGI:MGI:2451198\|PMID:12591243
Cellular Component	GO:0005886	plasma membrane	MGI:96610	Itgb1	IDA	Mouse	MGI:MGI:2655007\|PMID:12670870
Cellular Component	GO:0005886	plasma membrane	MGI:96610	Itgb1	IDA	Mouse	MGI:MGI:2677652\|PMID:14522949
Cellular Component	GO:0005886	plasma membrane	RGD:2927	Itgb1	ISS	Rat	RGD:1580654
Cellular Component	GO:0019717	synaptosome	MGI:96610	Itgb1	IDA	Mouse	MGI:MGI:2670471\|PMID:12904471
Cellular Component	GO:0019717	synaptosome	RGD:2927	Itgb1	ISS	Rat	RGD:1580654
Biological Process	GO:0007411	axon guidance	FBgn0004657	mys	IMP	Fly	FB:FBrf0149077\|PMID:12040052
Biological Process	GO:0008150	biological_process	WBGene00003930	pat-3	IMP	Worm	WB:WBPaper00005654\|PMID:12529635
Biological Process	GO:0016340	calcium-dependent cell-matrix adhesion	FBgn0004657	mys	ISS	Fly	FB:FBrf0129868\|PMID:10908592
Biological Process	GO:0042685	cardioblast cell fate specification	MGI:96610	Itgb1	IMP	Mouse	MGI:MGI:84974\|PMID:9004034
Biological Process	GO:0010002	cardioblast differentiation	MGI:96610	Itgb1	IMP	Mouse	MGI:MGI:84974\|PMID:9004034
Biological Process	GO:0007155	cell adhesion	RGD:2927	Itgb1	ISS	Rat	RGD:1302874\|PMID:9633916
Biological Process	GO:0007155	cell adhesion	RGD:2927	Itgb1	IDA	Rat	RGD:1625134\|PMID:12639933
Biological Process	GO:0007155	cell adhesion	FBgn0004657	mys	IMP	Fly	FB:FBrf0167741\|PMID:14527345
Biological Process	GO:0016477	cell migration	WBGene00003930	pat-3	IMP	Worm	WB:WBPaper00005218\|PMID:11967148
Biological Process	GO:0006874	cellular calcium ion homeostasis	RGD:2927	Itgb1	IDA	Rat	RGD:1625134\|PMID:12639933
Biological Process	GO:0007417	central nervous system development	FBgn0004657	mys	IMP	Fly	FB:FBrf0049500\|PMID:2492244
Biological Process	GO:0008340	determination of adult life span	WBGene00003930	pat-3	IMP	Worm	WB:WBPaper00005654\|PMID:12529635
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00003930	pat-3	IMP	Worm	WB:WBPaper00004651\|PMID:11231151
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00003930	pat-3	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	MGI:96610	Itgb1	IMP	Mouse	MGI:MGI:2675790\|PMID:12957148
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	RGD:2927	Itgb1	ISS	Rat	RGD:1580654
Biological Process	GO:0035099	hemocyte migration	FBgn0004657	mys	IGI	Fly	FB:FBrf0192108\|PMID:16818452
Biological Process	GO:0001701	in utero embryonic development	MGI:96610	Itgb1	IMP	Mouse	MGI:MGI:75950\|PMID:7544313
Biological Process	GO:0007229	integrin-mediated signaling pathway	RGD:2927	Itgb1	ISS	Rat	RGD:1302874\|PMID:9633916
Biological Process	GO:0007229	integrin-mediated signaling pathway	RGD:2927	Itgb1	IDA	Rat	RGD:1625134\|PMID:12639933
Biological Process	GO:0007626	locomotory behavior	WBGene00003930	pat-3	IMP	Worm	WB:WBPaper00005654\|PMID:12529635
Biological Process	GO:0035160	maintenance of epithelial integrity, open tracheal system	FBgn0004657	mys	IMP	Fly	FB:FBrf0193035\|PMID:16720877
Biological Process	GO:0007275	multicellular organismal development	RGD:2927	Itgb1	ISS	Rat	RGD:1580654
Biological Process	GO:0055001	muscle cell development	WBGene00003930	pat-3	IMP	Worm	WB:WBPaper00001894\|PMID:8106547
Biological Process	GO:0007517	muscle development	FBgn0004657	mys	IMP	Fly	FB:FBrf0049500\|PMID:2492244
Biological Process	GO:0045596	negative regulation of cell differentiation	MGI:96610	Itgb1	IMP	Mouse	MGI:MGI:3573843\|PMID:15056720
Biological Process	GO:0045596	negative regulation of cell differentiation	RGD:2927	Itgb1	ISS	Rat	RGD:1580654
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:96610	Itgb1	IMP	Mouse	MGI:MGI:3573843\|PMID:15056720
Biological Process	GO:0008284	positive regulation of cell proliferation	RGD:2927	Itgb1	ISS	Rat	RGD:1580654
Biological Process	GO:0043410	positive regulation of MAPKKK cascade	RGD:2927	Itgb1	IDA	Rat	RGD:1625134\|PMID:12639933
Biological Process	GO:0008360	regulation of cell shape	FBgn0004657	mys	IMP	Fly	FB:FBrf0167741\|PMID:14527345
Biological Process	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	RGD:2927	Itgb1	IMP	Rat	RGD:1625132\|PMID:17157995
Biological Process	GO:0000074	regulation of progression through cell cycle	MGI:96610	Itgb1	IMP	Mouse	MGI:MGI:2677652\|PMID:14522949
Biological Process	GO:0000074	regulation of progression through cell cycle	RGD:2927	Itgb1	ISS	Rat	RGD:1580654
Biological Process	GO:0000003	reproduction	WBGene00003930	pat-3	IMP	Worm	WB:WBPaper00005654\|PMID:12529635
Biological Process	GO:0000003	reproduction	WBGene00003930	pat-3	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0000003	reproduction	WBGene00003930	pat-3	IMP	Worm	WB:WBPaper00024681\|PMID:15642374
Biological Process	GO:0045214	sarcomere organization	MGI:96610	Itgb1	IMP	Mouse	MGI:MGI:84974\|PMID:9004034
Biological Process	GO:0006930	substrate-bound cell migration, cell extension	FBgn0004657	mys	IGI	Fly	FB:FBrf0192108\|PMID:16818452
Biological Process	GO:0001894	tissue homeostasis	RGD:2927	Itgb1	IMP	Rat	RGD:1625131\|PMID:17118629

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)