Compare GO annotations for HomoloGene:2395 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0005178	integrin binding	RGD:620404	Adam17	ISS	Rat	RGD:1559180\|PMID:14970227
Molecular Function	GO:0004222	metalloendopeptidase activity	RGD:620404	Adam17	IMP	Rat	RGD:632022\|PMID:11884025
Molecular Function	GO:0004222	metalloendopeptidase activity	FBgn0039734	Tace	ISS	Fly	FB:FBrf0105495
Molecular Function	GO:0005515	protein binding	P78536	ADA17_HUMAN	IPI	Human	PMID:10527948
Molecular Function	GO:0005515	protein binding	RGD:620404	Adam17	ISS	Rat	RGD:1580655
Molecular Function	GO:0004872	receptor activity	RGD:620404	Adam17	ISS	Rat	RGD:1580654
Cellular Component	GO:0005737	cytoplasm	MGI:1096335	Adam17	IDA	Mouse	MGI:MGI:3574221\|PMID:15739225
Cellular Component	GO:0005737	cytoplasm	RGD:620404	Adam17	ISS	Rat	RGD:1580654
Cellular Component	GO:0005925	focal adhesion	RGD:620404	Adam17	ISS	Rat	RGD:1559180\|PMID:14970227
Cellular Component	GO:0016021	integral to membrane	RGD:620404	Adam17	ISS	Rat	RGD:1580654
Cellular Component	GO:0005887	integral to plasma membrane	RGD:620404	Adam17	ISS	Rat	RGD:1580655
Cellular Component	GO:0001726	ruffle	RGD:620404	Adam17	ISS	Rat	RGD:1559180\|PMID:14970227
Biological Process	GO:0006916	anti-apoptosis	RGD:620404	Adam17	IDA	Rat	RGD:632021\|PMID:11973430
Biological Process	GO:0016337	cell-cell adhesion	RGD:620404	Adam17	ISS	Rat	RGD:1559180\|PMID:14970227
Biological Process	GO:0007267	cell-cell signaling	RGD:620404	Adam17	ISS	Rat	RGD:1580655
Biological Process	GO:0016485	protein processing	RGD:620404	Adam17	ISS	Rat	RGD:1559180\|PMID:14970227

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)