Compare GO annotations for HomoloGene:2589 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0003677	DNA binding	RGD:620434	Pax8	IDA	Rat	RGD:1600302\|PMID:15888455
Molecular Function	GO:0003677	DNA binding	RGD:620434	Pax8	IMP	Rat	RGD:727430\|PMID:12237116
Molecular Function	GO:0005515	protein binding	Q06710	PAX8_HUMAN	ISS	Human	UniProt:Q06710
Molecular Function	GO:0005515	protein binding	MGI:97492	Pax8	IPI	Mouse	MGI:MGI:3693390\|PMID:12441357
Molecular Function	GO:0005515	protein binding	RGD:620434	Pax8	ISS	Rat	RGD:1600115
Molecular Function	GO:0043565	sequence-specific DNA binding	RGD:620434	Pax8	IDA	Rat	RGD:628521\|PMID:11145590
Molecular Function	GO:0016563	transcription activator activity	Q06710	PAX8_HUMAN	ISS	Human	UniProt:Q06710
Molecular Function	GO:0016563	transcription activator activity	MGI:97492	Pax8	IDA	Mouse	MGI:MGI:3693390\|PMID:12441357
Molecular Function	GO:0016563	transcription activator activity	RGD:620434	Pax8	ISS	Rat	RGD:1600115
Molecular Function	GO:0016563	transcription activator activity	RGD:620434	Pax8	IDA	Rat	RGD:727430\|PMID:12237116
Molecular Function	GO:0003700	transcription factor activity	RGD:620434	Pax8	ISS	Rat	RGD:1580654
Molecular Function	GO:0003700	transcription factor activity	RGD:620434	Pax8	ISS	Rat	RGD:1580655
Molecular Function	GO:0003700	transcription factor activity	WB:WP:CE05215	EGL-38	ISS	Worm	WB:WBPaper00002924\|PMID:9374390
Cellular Component	GO:0005654	nucleoplasm	Q06710	PAX8_HUMAN	ISS	Human	UniProt:Q06710
Cellular Component	GO:0005654	nucleoplasm	RGD:620434	Pax8	IDA	Rat	RGD:null
Cellular Component	GO:0005634	nucleus	RGD:620434	Pax8	IDA	Rat	RGD:628521\|PMID:11145590
Cellular Component	GO:0005634	nucleus	RGD:620434	Pax8	ISS	Rat	RGD:1580655
Cellular Component	GO:0005634	nucleus	WB:WP:CE05215	EGL-38	IDA	Worm	WB:WBPaper00002235\|PMID:7659160
Cellular Component	GO:0005667	transcription factor complex	RGD:620434	Pax8	ISS	Rat	RGD:1580654
Biological Process	GO:0009653	anatomical structure morphogenesis	RGD:620434	Pax8	ISS	Rat	RGD:1580655
Biological Process	GO:0030154	cell differentiation	MGI:97492	Pax8	IMP	Mouse	MGI:MGI:1203285\|PMID:9590297
Biological Process	GO:0045165	cell fate commitment	WBGene00001204	egl-38	IMP	Worm	WB:WBPaper00002924\|PMID:9374390
Biological Process	GO:0002119	larval development (sensu Nematoda)	WBGene00001204	egl-38	IMP	Worm	WB:WBPaper00002924\|PMID:9374390
Biological Process	GO:0001656	metanephros development	MGI:97492	Pax8	IGI	Mouse	MGI:MGI:2445273\|PMID:12435636
Biological Process	GO:0001656	metanephros development	RGD:620434	Pax8	ISS	Rat	RGD:1580654
Biological Process	GO:0009887	organ morphogenesis	RGD:620434	Pax8	ISS	Rat	RGD:1580654
Biological Process	GO:0043049	otic placode formation	ZDB-GENE-001030-3	pax8	IMP	Zfin	ZFIN:ZDB-PUB-041228-8\|PMID:15604103
Biological Process	GO:0043049	otic placode formation	ZDB-GENE-001030-3	pax8	IGI	Zfin	ZFIN:ZDB-PUB-041228-8\|PMID:15604103
Biological Process	GO:0043049	otic placode formation	ZDB-GENE-001030-3	pax8	IGI	Zfin	ZFIN:ZDB-PUB-041006-7\|PMID:15459102
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:97492	Pax8	ISS	Mouse	MGI:MGI:892799\|PMID:9214635
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	RGD:620434	Pax8	IDA	Rat	RGD:9214635
Biological Process	GO:0045893	positive regulation of transcription, DNA-dependent	Q06710	PAX8_HUMAN	ISS	Human	UniProt:Q06710
Biological Process	GO:0045893	positive regulation of transcription, DNA-dependent	MGI:97492	Pax8	IDA	Mouse	MGI:MGI:3693390\|PMID:12441357
Biological Process	GO:0006355	regulation of transcription, DNA-dependent	RGD:620434	Pax8	IMP	Rat	RGD:628521\|PMID:11145590
Biological Process	GO:0006355	regulation of transcription, DNA-dependent	RGD:620434	Pax8	ISS	Rat	RGD:1580654
Biological Process	GO:0030878	thyroid gland development	MGI:97492	Pax8	IMP	Mouse	MGI:MGI:1203285\|PMID:9590297
Biological Process	GO:0040025	vulval development (sensu Nematoda)	WBGene00001204	egl-38	IMP	Worm	WB:WBPaper00002924\|PMID:9374390

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)