Compare GO annotations for HomoloGene:2903 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Q13144	EI2BE_HUMAN	ISS	Human	UniProt:Q13144
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Q13144	EI2BE_HUMAN	IMP	Human	PMID:15054402
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Q13144	EI2BE_HUMAN	IDA	Human	PMID:11323413
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	MGI:2446176	Eif2b5	ISS	Mouse	MGI:MGI:2154458
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RGD:708380	Eif2b5	IDA	Rat	RGD:1581073\|PMID:9139680
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RGD:708380	Eif2b5	IDA	Rat	RGD:1581075\|PMID:9582312
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RGD:708380	Eif2b5	IMP	Rat	RGD:1581085\|PMID:11500362
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RGD:708380	Eif2b5	ISS	Rat	RGD:1600115
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	FBgn0023512	eIF2B-epsilon	IDA	Fly	FB:FBrf0132369\|PMID:11060303
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	FBgn0023512	eIF2B-epsilon	ISS	Fly	FB:FBrf0132369\|PMID:11060303
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	S000002619	GCD6	IMP	Yeast	SGD_REF:S000043313\|PMID:10805739
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	S000002619	GCD6	IDA	Yeast	SGD_REF:S000048920\|PMID:9472020
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	S000002619	GCD6	IMP	Yeast	SGD_REF:S000071799\|PMID:12356745
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	SPAC8C9.15c	tif225	ISS	Pombe	GOC:unpublished
Molecular Function	GO:0005515	protein binding	Q13144	EI2BE_HUMAN	ISS	Human	UniProt:Q13144
Molecular Function	GO:0005515	protein binding	Q13144	EI2BE_HUMAN	IPI	Human	PMID:15060152
Molecular Function	GO:0005515	protein binding	MGI:2446176	Eif2b5	ISS	Mouse	MGI:MGI:2154458
Molecular Function	GO:0003743	translation initiation factor activity	Q13144	EI2BE_HUMAN	IDA	Human	PMID:16289705
Molecular Function	GO:0003743	translation initiation factor activity	RGD:708380	Eif2b5	ISS	Rat	RGD:1580655
Molecular Function	GO:0003743	translation initiation factor activity	RGD:708380	Eif2b5	ISS	Rat	RGD:1600115
Molecular Function	GO:0003743	translation initiation factor activity	FBgn0023512	eIF2B-epsilon	ISS	Fly	FB:FBrf0071734
Molecular Function	GO:0003743	translation initiation factor activity	FBgn0023512	eIF2B-epsilon	ISS	Fly	FB:FBrf0129923\|PMID:10908586
Molecular Function	GO:0003743	translation initiation factor activity	FBgn0023512	eIF2B-epsilon	ISS	Fly	FB:FBrf0132369\|PMID:11060303
Molecular Function	GO:0003743	translation initiation factor activity	S000002619	GCD6	IPI	Yeast	SGD_REF:S000049992\|PMID:8336705
Molecular Function	GO:0003743	translation initiation factor activity	S000002619	GCD6	IGI	Yeast	SGD_REF:S000049992\|PMID:8336705
Molecular Function	GO:0003743	translation initiation factor activity	SPAC8C9.15c	tif225	ISS	Pombe	GOC:unpublished
Molecular Function	GO:0031369	translation initiation factor binding	RGD:708380	Eif2b5	IDA	Rat	RGD:1581068\|PMID:9446619
Molecular Function	GO:0031369	translation initiation factor binding	RGD:708380	Eif2b5	IMP	Rat	RGD:1581085\|PMID:11500362
Cellular Component	GO:0005737	cytoplasm	Q13144	EI2BE_HUMAN	IDA	Human	PMID:11323413
Cellular Component	GO:0005737	cytoplasm	MGI:2446176	Eif2b5	IDA	Mouse	MGI:MGI:2450792\|PMID:12388085
Cellular Component	GO:0005737	cytoplasm	RGD:708380	Eif2b5	ISS	Rat	RGD:1580654
Cellular Component	GO:0005737	cytoplasm	RGD:708380	Eif2b5	ISS	Rat	RGD:1600115
Cellular Component	GO:0005829	cytosol	FBgn0023512	eIF2B-epsilon	ISS	Fly	FB:FBrf0071734
Cellular Component	GO:0005829	cytosol	FBgn0023512	eIF2B-epsilon	ISS	Fly	FB:FBrf0129923\|PMID:10908586
Cellular Component	GO:0005829	cytosol	SPAC8C9.15c	tif225	IDA	Pombe	PMID:16823372
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	Q13144	EI2BE_HUMAN	IDA	Human	PMID:11323413
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	Q13144	EI2BE_HUMAN	IDA	Human	PMID:15060152
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	MGI:2446176	Eif2b5	ISS	Mouse	MGI:MGI:2154458
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	RGD:708380	Eif2b5	IDA	Rat	RGD:1581073\|PMID:9139680
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	RGD:708380	Eif2b5	IDA	Rat	RGD:1581075\|PMID:9582312
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	RGD:708380	Eif2b5	ISS	Rat	RGD:1600115
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	FBgn0023512	eIF2B-epsilon	ISS	Fly	FB:FBrf0129923\|PMID:10908586
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000002619	GCD6	IMP	Yeast	SGD_REF:S000048683\|PMID:8441423
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000002619	GCD6	IDA	Yeast	SGD_REF:S000048815\|PMID:8506384
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000002619	GCD6	IGI	Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000002619	GCD6	IPI	Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000002619	GCD6	IPI	Yeast	SGD_REF:S000048815\|PMID:8506384
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000002619	GCD6	IDA	Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	SPAC8C9.15c	tif225	ISS	Pombe	GOC:unpublished
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	S000002619	GCD6	IPI	Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	S000002619	GCD6	IDA	Yeast	SGD_REF:S000048920\|PMID:9472020
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	S000002619	GCD6	IDA	Yeast	SGD_REF:S000048815\|PMID:8506384
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	S000002619	GCD6	IPI	Yeast	SGD_REF:S000048920\|PMID:9472020
Cellular Component	GO:0005634	nucleus	MGI:2446176	Eif2b5	IDA	Mouse	MGI:MGI:2450792\|PMID:12388085
Cellular Component	GO:0005634	nucleus	RGD:708380	Eif2b5	ISS	Rat	RGD:1580654
Biological Process	GO:0006520	amino acid metabolic process	RGD:708380	Eif2b5	ISS	Rat	RGD:1580655
Biological Process	GO:0014002	astrocyte development	Q13144	EI2BE_HUMAN	IMP	Human	PMID:15723074
Biological Process	GO:0014002	astrocyte development	RGD:708380	Eif2b5	ISS	Rat	RGD:1600115
Biological Process	GO:0051716	cellular response to stimulus	Q13144	EI2BE_HUMAN	IDA	Human	PMID:8626696
Biological Process	GO:0051716	cellular response to stimulus	RGD:708380	Eif2b5	ISS	Rat	RGD:1600115
Biological Process	GO:0042552	myelination	Q13144	EI2BE_HUMAN	IMP	Human	PMID:14566705
Biological Process	GO:0042552	myelination	Q13144	EI2BE_HUMAN	IMP	Human	PMID:15723074
Biological Process	GO:0042552	myelination	RGD:708380	Eif2b5	ISS	Rat	RGD:1600115
Biological Process	GO:0032057	negative regulation of translation initiation in response to stress	RGD:708380	Eif2b5	IMP	Rat	RGD:1581066\|PMID:11463353
Biological Process	GO:0014003	oligodendrocyte development	Q13144	EI2BE_HUMAN	IMP	Human	PMID:15217090
Biological Process	GO:0014003	oligodendrocyte development	RGD:708380	Eif2b5	ISS	Rat	RGD:1600115
Biological Process	GO:0001541	ovarian follicle development	Q13144	EI2BE_HUMAN	IMP	Human	PMID:15507143
Biological Process	GO:0001541	ovarian follicle development	RGD:708380	Eif2b5	ISS	Rat	RGD:1600115
Biological Process	GO:0045948	positive regulation of translational initiation	Q13144	EI2BE_HUMAN	ISS	Human	UniProt:Q13144
Biological Process	GO:0045948	positive regulation of translational initiation	RGD:708380	Eif2b5	ISS	Rat	RGD:1600115
Biological Process	GO:0006417	regulation of translation	RGD:708380	Eif2b5	IMP	Rat	RGD:1581064\|PMID:11804848
Biological Process	GO:0006446	regulation of translational initiation	RGD:708380	Eif2b5	ISS	Rat	RGD:1580655
Biological Process	GO:0006446	regulation of translational initiation	S000002619	GCD6	IPI	Yeast	SGD_REF:S000049992\|PMID:8336705
Biological Process	GO:0006446	regulation of translational initiation	S000002619	GCD6	IDA	Yeast	SGD_REF:S000048815\|PMID:8506384
Biological Process	GO:0006446	regulation of translational initiation	S000002619	GCD6	IGI	Yeast	SGD_REF:S000049992\|PMID:8336705
Biological Process	GO:0009749	response to glucose stimulus	Q13144	EI2BE_HUMAN	ISS	Human	UniProt:Q13144
Biological Process	GO:0009749	response to glucose stimulus	RGD:708380	Eif2b5	IDA	Rat	RGD:null
Biological Process	GO:0009408	response to heat	Q13144	EI2BE_HUMAN	ISS	Human	UniProt:Q13144
Biological Process	GO:0009408	response to heat	Q13144	EI2BE_HUMAN	IMP	Human	PMID:15723074
Biological Process	GO:0009408	response to heat	RGD:708380	Eif2b5	IDA	Rat	RGD:null
Biological Process	GO:0009408	response to heat	RGD:708380	Eif2b5	ISS	Rat	RGD:1600115
Biological Process	GO:0043434	response to peptide hormone stimulus	Q13144	EI2BE_HUMAN	ISS	Human	UniProt:Q13144
Biological Process	GO:0043434	response to peptide hormone stimulus	RGD:708380	Eif2b5	IDA	Rat	RGD:null
Biological Process	GO:0006413	translational initiation	FBgn0023512	eIF2B-epsilon	ISS	Fly	FB:FBrf0071734
Biological Process	GO:0006413	translational initiation	FBgn0023512	eIF2B-epsilon	ISS	Fly	FB:FBrf0129923\|PMID:10908586
Biological Process	GO:0006413	translational initiation	FBgn0023512	eIF2B-epsilon	ISS	Fly	FB:FBrf0132369\|PMID:11060303
Biological Process	GO:0006413	translational initiation	SPAC8C9.15c	tif225	ISS	Pombe	GOC:unpublished

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)