Compare GO annotations for HomoloGene:30961 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0043498	cell surface binding	FBgn0004644	hh	IDA	Fly	FB:FBrf0189929\|PMID:16630821
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	FBgn0004644	hh	ISS	Fly	FB:FBrf0126658
Molecular Function	GO:0043237	laminin-1 binding	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Molecular Function	GO:0043237	laminin-1 binding	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3573843\|PMID:15056720
Molecular Function	GO:0043237	laminin-1 binding	RGD:3673	Shh	ISS	Rat	RGD:1580654
Molecular Function	GO:0043237	laminin-1 binding	RGD:3673	Shh	ISS	Rat	RGD:1600115
Molecular Function	GO:0005113	patched binding	MGI:98297	Shh	IPI	Mouse	MGI:MGI:3687672\|PMID:10500113
Molecular Function	GO:0005515	protein binding	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Molecular Function	GO:0005515	protein binding	MGI:98297	Shh	IPI	Mouse	MGI:MGI:3687672\|PMID:10500113
Molecular Function	GO:0005515	protein binding	RGD:3673	Shh	ISS	Rat	RGD:1580654
Cellular Component	GO:0009986	cell surface	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Cellular Component	GO:0009986	cell surface	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3511726\|PMID:15576403
Cellular Component	GO:0009986	cell surface	RGD:3673	Shh	ISS	Rat	RGD:1580654
Cellular Component	GO:0009986	cell surface	RGD:3673	Shh	ISS	Rat	RGD:1600115
Cellular Component	GO:0016023	cytoplasmic membrane-bound vesicle	FBgn0004644	hh	IDA	Fly	FB:FBrf0155685\|PMID:12586063
Cellular Component	GO:0005615	extracellular space	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Cellular Component	GO:0005615	extracellular space	MGI:98297	Shh	IDA	Mouse	MGI:MGI:2150931\|PMID:7891723
Cellular Component	GO:0005615	extracellular space	MGI:98297	Shh	IDA	Mouse	MGI:MGI:1329746\|PMID:10027293
Cellular Component	GO:0005615	extracellular space	RGD:3673	Shh	ISS	Rat	RGD:1580654
Cellular Component	GO:0005615	extracellular space	RGD:3673	Shh	ISS	Rat	RGD:1600115
Cellular Component	GO:0045121	lipid raft	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Cellular Component	GO:0045121	lipid raft	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3039193\|PMID:15075292
Cellular Component	GO:0045121	lipid raft	RGD:3673	Shh	ISS	Rat	RGD:1580654
Cellular Component	GO:0045121	lipid raft	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0007228	activation of hh target transcription factor	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3624046\|PMID:16611981
Biological Process	GO:0007228	activation of hh target transcription factor	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3653954\|PMID:16880529
Biological Process	GO:0007228	activation of hh target transcription factor	FBgn0004644	hh	IGI	Fly	FB:FBrf0105900\|PMID:9874371
Biological Process	GO:0048856	anatomical structure development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2148409\|PMID:11485934
Biological Process	GO:0048646	anatomical structure formation	MGI:98297	Shh	IMP	Mouse	MGI:MGI:1289788\|PMID:9768363
Biological Process	GO:0008209	androgen metabolic process	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0008209	androgen metabolic process	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3037217\|PMID:15013801
Biological Process	GO:0008209	androgen metabolic process	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0008209	androgen metabolic process	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0001525	angiogenesis	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3629544\|PMID:16778080
Biological Process	GO:0001525	angiogenesis	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3701403\|PMID:17187775
Biological Process	GO:0001525	angiogenesis	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3701403\|PMID:17187775
Biological Process	GO:0001525	angiogenesis	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0021960	anterior commissure morphogenesis	FBgn0004644	hh	IMP	Fly	FB:FBrf0190277\|PMID:16467357
Biological Process	GO:0009952	anterior/posterior pattern formation	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2135419\|PMID:11389830
Biological Process	GO:0007411	axon guidance	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0007411	axon guidance	MGI:98297	Shh	IDA	Mouse	MGI:MGI:2654974\|PMID:12679031
Biological Process	GO:0007411	axon guidance	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2662556\|PMID:12756179
Biological Process	GO:0007411	axon guidance	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0007411	axon guidance	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0060020	Bergmann glial cell differentiation	MGI:98297	Shh	IDA	Mouse	MGI:MGI:1338342\|PMID:10375501
Biological Process	GO:0001746	Bolwig's organ morphogenesis	FBgn0004644	hh	IMP	Fly	FB:FBrf0126773\|PMID:10704398
Biological Process	GO:0007420	brain development	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-030707-3\|PMID:12843251
Biological Process	GO:0048754	branching morphogenesis of a tube	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3039063\|PMID:15042696
Biological Process	GO:0048754	branching morphogenesis of a tube	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3050270\|PMID:15305287
Biological Process	GO:0048754	branching morphogenesis of a tube	MGI:98297	Shh	IMP	Mouse	MGI:MGI:1289788\|PMID:9768363
Biological Process	GO:0048754	branching morphogenesis of a tube	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0043010	camera-type eye development	MGI:98297	Shh	IDA	Mouse	MGI:MGI:2385969\|PMID:12195432
Biological Process	GO:0043010	camera-type eye development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2662556\|PMID:12756179
Biological Process	GO:0043010	camera-type eye development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3608482\|PMID:16236765
Biological Process	GO:0043010	camera-type eye development	ZDB-GENE-980526-166	shha	IDA	Zfin	ZFIN:ZDB-PUB-050426-1\|PMID:15728669
Biological Process	GO:0048468	cell development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3051930\|PMID:15183722
Biological Process	GO:0048468	cell development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3608482\|PMID:16236765
Biological Process	GO:0048468	cell development	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0001708	cell fate specification	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0001708	cell fate specification	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2387225\|PMID:12231626
Biological Process	GO:0001708	cell fate specification	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3624618\|PMID:16647304
Biological Process	GO:0001708	cell fate specification	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0001708	cell fate specification	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0001708	cell fate specification	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-040706-2\|PMID:15229178
Biological Process	GO:0007267	cell-cell signaling	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0007267	cell-cell signaling	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3045497\|PMID:15199404
Biological Process	GO:0007267	cell-cell signaling	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3617552\|PMID:16492970
Biological Process	GO:0007267	cell-cell signaling	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0007267	cell-cell signaling	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0007417	central nervous system development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2445271\|PMID:12435628
Biological Process	GO:0007417	central nervous system development	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0007417	central nervous system development	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0007417	central nervous system development	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-030919-9\|PMID:13129844
Biological Process	GO:0008015	circulation	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-970210-25\|PMID:9007249
Biological Process	GO:0035231	cytoneme biogenesis	FBgn0004644	hh	IMP	Fly	FB:FBrf0109017\|PMID:10367889
Biological Process	GO:0048589	developmental growth	MGI:98297	Shh	IMP	Mouse	MGI:MGI:1926240\|PMID:11044393
Biological Process	GO:0009953	dorsal/ventral pattern formation	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3051703\|PMID:15269168
Biological Process	GO:0009953	dorsal/ventral pattern formation	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0009953	dorsal/ventral pattern formation	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-041115-5\|PMID:15539490
Biological Process	GO:0031076	embryonic camera-type eye development	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-050506-5\|PMID:15857917
Biological Process	GO:0009790	embryonic development	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3588476\|PMID:16020517
Biological Process	GO:0009790	embryonic development	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0042733	embryonic digit morphogenesis	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0042733	embryonic digit morphogenesis	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3579954\|PMID:15930098
Biological Process	GO:0042733	embryonic digit morphogenesis	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0042733	embryonic digit morphogenesis	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0030326	embryonic limb morphogenesis	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3053241\|PMID:15315763
Biological Process	GO:0030326	embryonic limb morphogenesis	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2135419\|PMID:11389830
Biological Process	GO:0030326	embryonic limb morphogenesis	MGI:98297	Shh	IGI	Mouse	MGI:MGI:2135419\|PMID:11389830
Biological Process	GO:0030326	embryonic limb morphogenesis	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0030326	embryonic limb morphogenesis	Q91035	SHH_CHICK	IMP	Chicken	PMID:8269518
Biological Process	GO:0048598	embryonic morphogenesis	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3617552\|PMID:16492970
Biological Process	GO:0048598	embryonic morphogenesis	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	ZDB-GENE-980526-166	shha	IGI	Zfin	ZFIN:ZDB-PUB-050803-5\|PMID:16049113
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-050803-5\|PMID:16049113
Biological Process	GO:0048568	embryonic organ development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3612368\|PMID:15680353
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-060412-2\|PMID:16580747
Biological Process	GO:0007427	epithelial cell migration, open tracheal system	FBgn0004644	hh	IMP	Fly	FB:FBrf0135726\|PMID:11290298
Biological Process	GO:0048592	eye morphogenesis	FBgn0004644	hh	IMP	Fly	FB:FBrf0193969\|PMID:16651542
Biological Process	GO:0042462	eye photoreceptor cell development	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-040719-3\|PMID:15253932
Biological Process	GO:0042462	eye photoreceptor cell development	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-050518-13\|PMID:15891769
Biological Process	GO:0021508	floor plate formation	ZDB-GENE-980526-166	shha	IGI	Zfin	ZFIN:ZDB-PUB-030115-17\|PMID:12508225
Biological Process	GO:0030900	forebrain development	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0030900	forebrain development	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3588476\|PMID:16020517
Biological Process	GO:0030900	forebrain development	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0030900	forebrain development	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0030900	forebrain development	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-060207-11\|PMID:16452095
Biological Process	GO:0035224	genital disc anterior/posterior pattern formation	FBgn0004644	hh	IEP	Fly	FB:FBrf0088118\|PMID:8798147
Biological Process	GO:0035215	genital disc development	FBgn0004644	hh	IMP	Fly	FB:FBrf0187379\|PMID:15893978
Biological Process	GO:0008354	germ cell migration	FBgn0004644	hh	IMP	Fly	FB:FBrf0100771\|PMID:9435287
Biological Process	GO:0010001	glial cell differentiation	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-040719-3\|PMID:15253932
Biological Process	GO:0008347	glial cell migration	FBgn0004644	hh	IMP	Fly	FB:FBrf0145174\|PMID:11804568
Biological Process	GO:0042063	gliogenesis	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-041115-5\|PMID:15539490
Biological Process	GO:0042063	gliogenesis	ZDB-GENE-980526-166	shha	IGI	Zfin	ZFIN:ZDB-PUB-041115-5\|PMID:15539490
Biological Process	GO:0007506	gonadal mesoderm development	FBgn0004644	hh	IMP	Fly	FB:FBrf0100771\|PMID:9435287
Biological Process	GO:0001942	hair follicle development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3589306\|PMID:16054035
Biological Process	GO:0031069	hair follicle morphogenesis	MGI:98297	Shh	IMP	Mouse	MGI:MGI:1289785\|PMID:9768360
Biological Process	GO:0007507	heart development	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0007507	heart development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3664714\|PMID:11172440
Biological Process	GO:0007507	heart development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3583396\|PMID:15936751
Biological Process	GO:0007507	heart development	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0007507	heart development	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0001947	heart looping	ZDB-GENE-980526-166	shha	IDA	Zfin	ZFIN:ZDB-PUB-971203-9\|PMID:9334285
Biological Process	GO:0030902	hindbrain development	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0030902	hindbrain development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3051930\|PMID:15183722
Biological Process	GO:0030902	hindbrain development	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3512837\|PMID:15496441
Biological Process	GO:0030902	hindbrain development	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0030902	hindbrain development	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0030902	hindbrain development	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-040804-3\|PMID:15281067
Biological Process	GO:0007442	hindgut morphogenesis	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2148409\|PMID:11485934
Biological Process	GO:0007442	hindgut morphogenesis	FBgn0004644	hh	IMP	Fly	FB:FBrf0134749\|PMID:11231061
Biological Process	GO:0008624	induction of apoptosis by extracellular signals	Q91035	SHH_CHICK	IMP	Chicken	PMID:11044396
Biological Process	GO:0001822	kidney development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3664714\|PMID:11172440
Biological Process	GO:0035217	labial disc development	FBgn0004644	hh	IMP	Fly	FB:FBrf0183854\|PMID:15680366
Biological Process	GO:0030324	lung development	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0030324	lung development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3701403\|PMID:17187775
Biological Process	GO:0030324	lung development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3050270\|PMID:15305287
Biological Process	GO:0030324	lung development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3051935\|PMID:15136151
Biological Process	GO:0030324	lung development	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3051935\|PMID:15136151
Biological Process	GO:0030324	lung development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:1289788\|PMID:9768363
Biological Process	GO:0030324	lung development	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0030324	lung development	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0030539	male genitalia development	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0030539	male genitalia development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2152294\|PMID:11684660
Biological Process	GO:0030539	male genitalia development	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0030539	male genitalia development	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0007500	mesodermal cell fate determination	RGD:3673	Shh	ISS	Rat	RGD:1580655
Biological Process	GO:0001656	metanephros development	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0001656	metanephros development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0001656	metanephros development	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0001656	metanephros development	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0030901	midbrain development	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0030901	midbrain development	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3588476\|PMID:16020517
Biological Process	GO:0030901	midbrain development	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0030901	midbrain development	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0016335	morphogenesis of larval imaginal disc epithelium	FBgn0004644	hh	IMP	Fly	FB:FBrf0190309\|PMID:16236766
Biological Process	GO:0046639	negative regulation of alpha-beta T cell differentiation	MGI:98297	Shh	IMP	Mouse	MGI:MGI:1888832\|PMID:10981962
Biological Process	GO:0043066	negative regulation of apoptosis	Q91035	SHH_CHICK	IMP	Chicken	PMID:11044396
Biological Process	GO:0045596	negative regulation of cell differentiation	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0045596	negative regulation of cell differentiation	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3053236\|PMID:15337776
Biological Process	GO:0045596	negative regulation of cell differentiation	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3608482\|PMID:16236765
Biological Process	GO:0045596	negative regulation of cell differentiation	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0045596	negative regulation of cell differentiation	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0030336	negative regulation of cell migration	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0030336	negative regulation of cell migration	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3053236\|PMID:15337776
Biological Process	GO:0030336	negative regulation of cell migration	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0030336	negative regulation of cell migration	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0008285	negative regulation of cell proliferation	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-050518-13\|PMID:15891769
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3624046\|PMID:16611981
Biological Process	GO:0042177	negative regulation of protein catabolic process	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3624046\|PMID:16611981
Biological Process	GO:0042130	negative regulation of T cell proliferation	MGI:98297	Shh	IMP	Mouse	MGI:MGI:1888832\|PMID:10981962
Biological Process	GO:0007399	nervous system development	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-030919-9\|PMID:13129844
Biological Process	GO:0001755	neural crest cell migration	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0001755	neural crest cell migration	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3583396\|PMID:15936751
Biological Process	GO:0001755	neural crest cell migration	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0001755	neural crest cell migration	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0001839	neural plate morphogenesis	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-060313-5\|PMID:16502420
Biological Process	GO:0001841	neural tube formation	RGD:3673	Shh	IMP	Rat	RGD:69996\|PMID:8124714
Biological Process	GO:0007405	neuroblast proliferation	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3053236\|PMID:15337776
Biological Process	GO:0007405	neuroblast proliferation	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0030182	neuron differentiation	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-060313-5\|PMID:16502420
Biological Process	GO:0030182	neuron differentiation	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-030707-3\|PMID:12843251
Biological Process	GO:0048663	neuron fate commitment	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0048663	neuron fate commitment	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3608263\|PMID:16221724
Biological Process	GO:0048663	neuron fate commitment	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0048663	neuron fate commitment	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0048663	neuron fate commitment	ZDB-GENE-980526-166	shha	IGI	Zfin	ZFIN:ZDB-PUB-041115-5\|PMID:15539490
Biological Process	GO:0042475	odontogenesis (sensu Vertebrata)	MGI:98297	Shh	IMP	Mouse	MGI:MGI:1926240\|PMID:11044393
Biological Process	GO:0014003	oligodendrocyte development	MGI:98297	Shh	IDA	Mouse	MGI:MGI:81674\|PMID:8660874
Biological Process	GO:0009887	organ morphogenesis	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0009887	organ morphogenesis	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2681050\|PMID:14623238
Biological Process	GO:0009887	organ morphogenesis	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0002076	osteoblast development	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3653954\|PMID:16880529
Biological Process	GO:0007389	pattern specification process	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0007389	pattern specification process	MGI:98297	Shh	IGI	Mouse	MGI:MGI:2683891\|PMID:14602680
Biological Process	GO:0007389	pattern specification process	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2387225\|PMID:12231626
Biological Process	GO:0007389	pattern specification process	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0007389	pattern specification process	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0001569	patterning of blood vessels	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0001569	patterning of blood vessels	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3583396\|PMID:15936751
Biological Process	GO:0001569	patterning of blood vessels	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0001569	patterning of blood vessels	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0033339	pectoral fin development	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-970210-21\|PMID:9007245
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:98297	Shh	IDA	Mouse	MGI:MGI:2154469\|PMID:11748155
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3051930\|PMID:15183722
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3512837\|PMID:15496441
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3608482\|PMID:16236765
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3589306\|PMID:16054035
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3589306\|PMID:16054035
Biological Process	GO:0008284	positive regulation of cell proliferation	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0021940	positive regulation of granule cell precursor proliferation	MGI:98297	Shh	IDA	Mouse	MGI:MGI:1329746\|PMID:10027293
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	MGI:98297	Shh	IDA	Mouse	MGI:MGI:2154469\|PMID:11748155
Biological Process	GO:0045666	positive regulation of neuron differentiation	RGD:3673	Shh	IMP	Rat	RGD:69996\|PMID:8124714
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3653954\|PMID:16880529
Biological Process	GO:0048618	post-embryonic foregut morphogenesis	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-030312-8\|PMID:12618131
Biological Process	GO:0007458	progression of morphogenetic furrow during compound eye morphogenesis	FBgn0004644	hh	IEP	Fly	FB:FBrf0064592\|PMID:8252628
Biological Process	GO:0007458	progression of morphogenetic furrow during compound eye morphogenesis	FBgn0004644	hh	IGI	Fly	FB:FBrf0064592\|PMID:8252628
Biological Process	GO:0007458	progression of morphogenetic furrow during compound eye morphogenesis	FBgn0004644	hh	IMP	Fly	FB:FBrf0064592\|PMID:8252628
Biological Process	GO:0030850	prostate gland development	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0030850	prostate gland development	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3037217\|PMID:15013801
Biological Process	GO:0030850	prostate gland development	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0030850	prostate gland development	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0016540	protein autoprocessing	FBgn0004644	hh	IDA	Fly	FB:FBrf0099245\|PMID:9335337
Biological Process	GO:0016540	protein autoprocessing	FBgn0004644	hh	IMP	Fly	FB:FBrf0099245\|PMID:9335337
Biological Process	GO:0042127	regulation of cell proliferation	MGI:98297	Shh	IDA	Mouse	MGI:MGI:2662556\|PMID:12756179
Biological Process	GO:0042127	regulation of cell proliferation	RGD:3673	Shh	IDA	Rat	RGD:628387\|PMID:12417650
Biological Process	GO:0042127	regulation of cell proliferation	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0030856	regulation of epithelial cell differentiation	RGD:3673	Shh	IEP	Rat	RGD:1580346\|PMID:14651923
Biological Process	GO:0007346	regulation of progression through mitotic cell cycle	FBgn0004644	hh	IMP	Fly	FB:FBrf0135358\|PMID:11279500
Biological Process	GO:0042306	regulation of protein import into nucleus	FBgn0004644	hh	IMP	Fly	FB:FBrf0167511\|PMID:14597576
Biological Process	GO:0030162	regulation of proteolysis	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0030162	regulation of proteolysis	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3051935\|PMID:15136151
Biological Process	GO:0030162	regulation of proteolysis	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0030162	regulation of proteolysis	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0045449	regulation of transcription	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2136712\|PMID:11412027
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-020820-6\|PMID:12110173
Biological Process	GO:0048678	response to axon injury	RGD:3673	Shh	IMP	Rat	RGD:1580344\|PMID:15356205
Biological Process	GO:0007435	salivary gland morphogenesis	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0007435	salivary gland morphogenesis	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3039063\|PMID:15042696
Biological Process	GO:0007435	salivary gland morphogenesis	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0007435	salivary gland morphogenesis	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0007367	segment polarity determination	FBgn0004644	hh	IMP	Fly	FB:FBrf0187474\|PMID:15930099
Biological Process	GO:0007165	signal transduction	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0007165	signal transduction	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0007165	signal transduction	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0007224	smoothened signaling pathway	MGI:98297	Shh	IDA	Mouse	MGI:MGI:84001\|PMID:8906787
Biological Process	GO:0007224	smoothened signaling pathway	MGI:98297	Shh	IGI	Mouse	MGI:MGI:3051703\|PMID:15269168
Biological Process	GO:0007224	smoothened signaling pathway	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0007224	smoothened signaling pathway	FBgn0004644	hh	IGI	Fly	FB:FBrf0089881\|PMID:8700230
Biological Process	GO:0007224	smoothened signaling pathway	ZDB-GENE-980526-166	shha	IGI	Zfin	ZFIN:ZDB-PUB-060424-5\|PMID:16626681
Biological Process	GO:0021938	smoothened signaling pathway in regulation of granule cell precursor cell proliferation	MGI:98297	Shh	IMP	Mouse	MGI:MGI:1338342\|PMID:10375501
Biological Process	GO:0021938	smoothened signaling pathway in regulation of granule cell precursor cell proliferation	MGI:98297	Shh	IDA	Mouse	MGI:MGI:1338342\|PMID:10375501
Biological Process	GO:0021513	spinal cord dorsal/ventral patterning	MGI:98297	Shh	IMP	Mouse	MGI:MGI:2154468\|PMID:11748151
Biological Process	GO:0035277	spiracle morphogenesis, open tracheal system	FBgn0004644	hh	IMP	Fly	FB:FBrf0187474\|PMID:15930099
Biological Process	GO:0055002	striated muscle cell development	ZDB-GENE-980526-166	shha	IMP	Zfin	ZFIN:ZDB-PUB-010416-5\|PMID:11428131
Biological Process	GO:0051146	striated muscle cell differentiation	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3621570\|PMID:15238161
Biological Process	GO:0051146	striated muscle cell differentiation	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3621570\|PMID:15238161
Biological Process	GO:0051146	striated muscle cell differentiation	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0021978	telencephalon regionalization	MGI:98297	Shh	IMP	Mouse	MGI:MGI:1926244\|PMID:11060228
Biological Process	GO:0043587	tongue morphogenesis	RGD:3673	Shh	IMP	Rat	RGD:1580345\|PMID:15581865
Biological Process	GO:0001658	ureteric bud branching	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0001658	ureteric bud branching	MGI:98297	Shh	IMP	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0001658	ureteric bud branching	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0001658	ureteric bud branching	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0001570	vasculogenesis	Q15465	SHH_HUMAN	ISS	Human	UniProt:Q15465
Biological Process	GO:0001570	vasculogenesis	MGI:98297	Shh	IDA	Mouse	MGI:MGI:3051693\|PMID:15294868
Biological Process	GO:0001570	vasculogenesis	RGD:3673	Shh	ISS	Rat	RGD:1580654
Biological Process	GO:0001570	vasculogenesis	RGD:3673	Shh	ISS	Rat	RGD:1600115
Biological Process	GO:0007418	ventral midline development	RGD:3673	Shh	ISS	Rat	RGD:1580655
Biological Process	GO:0007418	ventral midline development	FBgn0004644	hh	IMP	Fly	FB:FBrf0190277\|PMID:16467357

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)