Compare GO annotations for HomoloGene:314 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0051087	chaperone binding	Q92574	TSC1_HUMAN	IPI	Human	PMID:10585443
Molecular Function	GO:0032794	GTPase activating protein binding	RGD:620124	Tsc1	IPI	Rat	RGD:1601351\|PMID:17379185
Molecular Function	GO:0030695	GTPase regulator activity	RGD:620124	Tsc1	IMP	Rat	RGD:1601406\|PMID:15611338
Molecular Function	GO:0019900	kinase binding	FBgn0026317	Tsc1	IPI	Fly	FB:FBrf0152245\|PMID:12172555
Molecular Function	GO:0005515	protein binding	RGD:620124	Tsc1	IMP	Rat	RGD:1601406\|PMID:15611338
Molecular Function	GO:0047485	protein N-terminus binding	Q92574	TSC1_HUMAN	IPI	Human	PMID:10806479
Molecular Function	GO:0047485	protein N-terminus binding	MGI:1929183	Tsc1	IPI	Mouse	PMID:10806479
Molecular Function	GO:0047485	protein N-terminus binding	RGD:620124	Tsc1	IPI	Rat	RGD:1601351\|PMID:17379185
Cellular Component	GO:0005884	actin filament	Q92574	TSC1_HUMAN	IDA	Human	PMID:10806479
Cellular Component	GO:0005938	cell cortex	Q92574	TSC1_HUMAN	IDA	Human	PMID:10806479
Cellular Component	GO:0005737	cytoplasm	Q92574	TSC1_HUMAN	IDA	Human	PMID:9580671
Cellular Component	GO:0005737	cytoplasm	MGI:1929183	Tsc1	IDA	Mouse	MGI:MGI:2155582\|PMID:11741832
Cellular Component	GO:0005737	cytoplasm	MGI:1929183	Tsc1	IDA	Mouse	MGI:MGI:3610880\|PMID:16286931
Cellular Component	GO:0044430	cytoskeletal part	RGD:620124	Tsc1	IDA	Rat	RGD:1601407\|PMID:12147258
Cellular Component	GO:0005829	cytosol	Q92574	TSC1_HUMAN	IDA	Human	PMID:10585443
Cellular Component	GO:0005829	cytosol	RGD:620124	Tsc1	IDA	Rat	RGD:1601407\|PMID:12147258
Cellular Component	GO:0030426	growth cone	RGD:620124	Tsc1	IDA	Rat	RGD:633519\|PMID:12226091
Cellular Component	GO:0030027	lamellipodium	Q92574	TSC1_HUMAN	IDA	Human	PMID:10806479
Cellular Component	GO:0005792	microsome	RGD:620124	Tsc1	IDA	Rat	RGD:1601407\|PMID:12147258
Cellular Component	GO:0043234	protein complex	Q92574	TSC1_HUMAN	IDA	Human	PMID:10585443
Cellular Component	GO:0043234	protein complex	RGD:620124	Tsc1	IMP	Rat	RGD:1601406\|PMID:15611338
Cellular Component	GO:0043234	protein complex	RGD:620124	Tsc1	IDA	Rat	RGD:1601351\|PMID:17379185
Biological Process	GO:0032862	activation of Rho GTPase	Q92574	TSC1_HUMAN	IDA	Human	PMID:10806479
Biological Process	GO:0055007	cardiac muscle cell differentiation	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:2137425\|PMID:11438694
Biological Process	GO:0007155	cell adhesion	RGD:620124	Tsc1	ISS	Rat	RGD:1580655
Biological Process	GO:0030030	cell projection organization and biogenesis	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3610880\|PMID:16286931
Biological Process	GO:0021987	cerebral cortex development	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3712408\|PMID:17522300
Biological Process	GO:0008340	determination of adult life span	FBgn0026317	Tsc1	IMP	Fly	FB:FBrf0179269\|PMID:15186745
Biological Process	GO:0009790	embryonic development	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3583848\|PMID:15888477
Biological Process	GO:0021766	hippocampus development	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3712408\|PMID:17522300
Biological Process	GO:0001822	kidney development	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3583848\|PMID:15888477
Biological Process	GO:0042552	myelination	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3712408\|PMID:17522300
Biological Process	GO:0030308	negative regulation of cell growth	FBgn0026317	Tsc1	IGI	Fly	FB:FBrf0135684\|PMID:11348591
Biological Process	GO:0030308	negative regulation of cell growth	FBgn0026317	Tsc1	IMP	Fly	FB:FBrf0135684\|PMID:11348591
Biological Process	GO:0008285	negative regulation of cell proliferation	Q92574	TSC1_HUMAN	IMP	Human	PMID:10915759
Biological Process	GO:0008285	negative regulation of cell proliferation	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:2137425\|PMID:11438694
Biological Process	GO:0008285	negative regulation of cell proliferation	FBgn0026317	Tsc1	IGI	Fly	FB:FBrf0135684\|PMID:11348591
Biological Process	GO:0045792	negative regulation of cell size	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3610880\|PMID:16286931
Biological Process	GO:0045792	negative regulation of cell size	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3613107\|PMID:15664737
Biological Process	GO:0045792	negative regulation of cell size	MGI:1929183	Tsc1	IGI	Mouse	MGI:MGI:3610880\|PMID:16286931
Biological Process	GO:0045792	negative regulation of cell size	MGI:1929183	Tsc1	IGI	Mouse	MGI:MGI:3613118\|PMID:15185396
Biological Process	GO:0045792	negative regulation of cell size	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3712408\|PMID:17522300
Biological Process	GO:0045792	negative regulation of cell size	FBgn0026317	Tsc1	IGI	Fly	FB:FBrf0136941\|PMID:11390358
Biological Process	GO:0045792	negative regulation of cell size	FBgn0026317	Tsc1	IMP	Fly	FB:FBrf0136941\|PMID:11390358
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	FBgn0026317	Tsc1	IGI	Fly	FB:FBrf0136941\|PMID:11390358
Biological Process	GO:0046621	negative regulation of organ size	FBgn0026317	Tsc1	IMP	Fly	FB:FBrf0135684\|PMID:11348591
Biological Process	GO:0046621	negative regulation of organ size	FBgn0026317	Tsc1	IGI	Fly	FB:FBrf0136941\|PMID:11390358
Biological Process	GO:0046621	negative regulation of organ size	FBgn0026317	Tsc1	IMP	Fly	FB:FBrf0136941\|PMID:11390358
Biological Process	GO:0017148	negative regulation of protein biosynthetic process	Q92574	TSC1_HUMAN	IMP	Human	PMID:17308101
Biological Process	GO:0032007	negative regulation of TOR signaling pathway	Q92574	TSC1_HUMAN	IMP	Human	PMID:17308101
Biological Process	GO:0007399	nervous system development	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3712408\|PMID:17522300
Biological Process	GO:0001843	neural tube closure	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:2137425\|PMID:11438694
Biological Process	GO:0051894	positive regulation of focal adhesion formation	Q92574	TSC1_HUMAN	IDA	Human	PMID:10806479
Biological Process	GO:0006813	potassium ion transport	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3695173\|PMID:16393152
Biological Process	GO:0006813	potassium ion transport	MGI:1929183	Tsc1	IGI	Mouse	MGI:MGI:3695173\|PMID:16393152
Biological Process	GO:0051291	protein heterooligomerization	RGD:620124	Tsc1	IDA	Rat	RGD:1601351\|PMID:17379185
Biological Process	GO:0032956	regulation of actin cytoskeleton organization and biogenesis	RGD:620124	Tsc1	IMP	Rat	RGD:1601406\|PMID:15611338
Biological Process	GO:0001952	regulation of cell-matrix adhesion	Q92574	TSC1_HUMAN	IMP	Human	PMID:10806479
Biological Process	GO:0051893	regulation of focal adhesion formation	RGD:620124	Tsc1	IMP	Rat	RGD:1601406\|PMID:15611338
Biological Process	GO:0043666	regulation of phosphoprotein phosphatase activity	Q92574	TSC1_HUMAN	IMP	Human	PMID:17308101
Biological Process	GO:0000074	regulation of progression through cell cycle	FBgn0026317	Tsc1	IMP	Fly	FB:FBrf0135684\|PMID:11348591
Biological Process	GO:0045859	regulation of protein kinase activity	MGI:1929183	Tsc1	IGI	Mouse	MGI:MGI:3613118\|PMID:15185396
Biological Process	GO:0051492	regulation of stress fiber formation	Q92574	TSC1_HUMAN	IDA	Human	PMID:10806479
Biological Process	GO:0051492	regulation of stress fiber formation	RGD:620124	Tsc1	IMP	Rat	RGD:1601406\|PMID:15611338
Biological Process	GO:0048505	regulation of timing of cell differentiation	FBgn0026317	Tsc1	IMP	Fly	FB:FBrf0180028\|PMID:15454083
Biological Process	GO:0032868	response to insulin stimulus	Q92574	TSC1_HUMAN	IDA	Human	PMID:16996505
Biological Process	GO:0007584	response to nutrient	FBgn0026317	Tsc1	IMP	Fly	FB:FBrf0152245\|PMID:12172555
Biological Process	GO:0007266	Rho protein signal transduction	RGD:620124	Tsc1	ISS	Rat	RGD:1580655
Biological Process	GO:0006407	rRNA export from nucleus	Q92574	TSC1_HUMAN	IMP	Human	PMID:17308101
Biological Process	GO:0007165	signal transduction	FBgn0026317	Tsc1	IGI	Fly	FB:FBrf0152245\|PMID:12172555
Biological Process	GO:0050808	synapse organization and biogenesis	MGI:1929183	Tsc1	IMP	Mouse	MGI:MGI:3610880\|PMID:16286931

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)