Compare GO annotations for HomoloGene:371 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0042623	ATPase activity, coupled	FBgn0015754	Lis-1	ISS	Fly	FB:FBrf0132100\|PMID:10908588
Molecular Function	GO:0045502	dynein binding	P43034	LIS1_HUMAN	IDA	Human	PMID:11889140
Molecular Function	GO:0045502	dynein binding	RGD:620331	Pafah1b1	ISS	Rat	RGD:1580655
Molecular Function	GO:0045505	dynein intermediate chain binding	RGD:620331	Pafah1b1	IDA	Rat	RGD:1601500\|PMID:11056530
Molecular Function	GO:0030234	enzyme regulator activity	FBgn0015754	Lis-1	ISS	Fly	FB:FBrf0105495
Molecular Function	GO:0030234	enzyme regulator activity	FBgn0015754	Lis-1	ISS	Fly	FB:FBrf0111489\|PMID:10471706
Molecular Function	GO:0008017	microtubule binding	MGI:109520	Pafah1b1	IDA	Mouse	MGI:MGI:1928566\|PMID:11163259
Molecular Function	GO:0005515	protein binding	MGI:109520	Pafah1b1	IPI	Mouse	MGI:MGI:1932152\|PMID:11231056
Cellular Component	GO:0005818	aster	WB:WP:CE29339	LIS-1	IDA	Worm	WB:WBPaper00024358\|PMID:15331665
Cellular Component	GO:0000235	astral microtubule	P43034	LIS1_HUMAN	IDA	Human	PMID:11940666
Cellular Component	GO:0000235	astral microtubule	RGD:620331	Pafah1b1	ISS	Rat	RGD:1580655
Cellular Component	GO:0005938	cell cortex	P43034	LIS1_HUMAN	IDA	Human	PMID:11940666
Cellular Component	GO:0005938	cell cortex	RGD:620331	Pafah1b1	ISS	Rat	RGD:1580655
Cellular Component	GO:0005938	cell cortex	WB:WP:CE29339	LIS-1	IDA	Worm	WB:WBPaper00024358\|PMID:15331665
Cellular Component	GO:0043025	cell soma	RGD:620331	Pafah1b1	IDA	Rat	RGD:1601500\|PMID:11056530
Cellular Component	GO:0005813	centrosome	MGI:109520	Pafah1b1	IDA	Mouse	MGI:MGI:1928548\|PMID:11163260
Cellular Component	GO:0005813	centrosome	MGI:109520	Pafah1b1	IDA	Mouse	MGI:MGI:1928566\|PMID:11163259
Cellular Component	GO:0005737	cytoplasm	MGI:109520	Pafah1b1	IDA	Mouse	MGI:MGI:2655038\|PMID:12551946
Cellular Component	GO:0005737	cytoplasm	MGI:109520	Pafah1b1	IDA	Mouse	MGI:MGI:2675555\|PMID:12950100
Cellular Component	GO:0005737	cytoplasm	WB:WP:CE29339	LIS-1	IDA	Worm	WB:WBPaper00024358\|PMID:15331665
Cellular Component	GO:0030286	dynein complex	FBgn0015754	Lis-1	ISS	Fly	FB:FBrf0132100\|PMID:10908588
Cellular Component	GO:0030426	growth cone	RGD:620331	Pafah1b1	IDA	Rat	RGD:1601500\|PMID:11056530
Cellular Component	GO:0005626	insoluble fraction	RGD:620331	Pafah1b1	IDA	Rat	RGD:1601500\|PMID:11056530
Cellular Component	GO:0000776	kinetochore	P43034	LIS1_HUMAN	IDA	Human	PMID:11940666
Cellular Component	GO:0000776	kinetochore	P43034	LIS1_HUMAN	IDA	Human	PMID:11056532
Cellular Component	GO:0000776	kinetochore	P43034	LIS1_HUMAN	IDA	Human	PMID:11889140
Cellular Component	GO:0000776	kinetochore	RGD:620331	Pafah1b1	ISS	Rat	RGD:1580655
Cellular Component	GO:0000776	kinetochore	WB:WP:CE29339	LIS-1	IDA	Worm	WB:WBPaper00024358\|PMID:15331665
Cellular Component	GO:0005874	microtubule	WB:WP:CE29339	LIS-1	IDA	Worm	WB:WBPaper00024358\|PMID:15331665
Cellular Component	GO:0005875	microtubule associated complex	P43034	LIS1_HUMAN	IDA	Human	PMID:11889140
Cellular Component	GO:0005875	microtubule associated complex	MGI:109520	Pafah1b1	IDA	Mouse	MGI:MGI:1928566\|PMID:11163259
Cellular Component	GO:0005875	microtubule associated complex	RGD:620331	Pafah1b1	ISS	Rat	RGD:1580655
Cellular Component	GO:0015630	microtubule cytoskeleton	MGI:109520	Pafah1b1	IDA	Mouse	MGI:MGI:2681371\|PMID:13129914
Cellular Component	GO:0005635	nuclear envelope	P43034	LIS1_HUMAN	IDA	Human	PMID:11940666
Cellular Component	GO:0005635	nuclear envelope	RGD:620331	Pafah1b1	ISS	Rat	RGD:1580655
Cellular Component	GO:0048471	perinuclear region of cytoplasm	WB:WP:CE29339	LIS-1	IDA	Worm	WB:WBPaper00024358\|PMID:15331665
Cellular Component	GO:0005625	soluble fraction	RGD:620331	Pafah1b1	IDA	Rat	RGD:1601500\|PMID:11056530
Cellular Component	GO:0042598	vesicular fraction	RGD:620331	Pafah1b1	IDA	Rat	RGD:1601500\|PMID:11056530
Biological Process	GO:0001675	acrosome formation	MGI:109520	Pafah1b1	IMP	Mouse	MGI:MGI:2681371\|PMID:13129914
Biological Process	GO:0016477	cell migration	MGI:109520	Pafah1b1	IMP	Mouse	MGI:MGI:2651971\|PMID:12629176
Biological Process	GO:0006928	cell motility	RGD:620331	Pafah1b1	ISS	Rat	RGD:1580655
Biological Process	GO:0051026	chiasma formation	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00029200\|PMID:17376425
Biological Process	GO:0040016	embryonic cleavage	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00024358\|PMID:15331665
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00004403\|PMID:11099034
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00004895\|PMID:11685578
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00005654\|PMID:12529635
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00025054\|PMID:15791247
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00029200\|PMID:17376425
Biological Process	GO:0043652	engulfment of apoptotic cell	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00029200\|PMID:17376425
Biological Process	GO:0040001	establishment of mitotic spindle localization	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00024358\|PMID:15331665
Biological Process	GO:0000132	establishment of mitotic spindle orientation	P43034	LIS1_HUMAN	IMP	Human	PMID:11056532
Biological Process	GO:0000132	establishment of mitotic spindle orientation	RGD:620331	Pafah1b1	ISS	Rat	RGD:1580655
Biological Process	GO:0000132	establishment of mitotic spindle orientation	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00024358\|PMID:15331665
Biological Process	GO:0007276	gamete generation	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00004895\|PMID:11685578
Biological Process	GO:0030706	germarium-derived oocyte differentiation	FBgn0015754	Lis-1	IMP	Fly	FB:FBrf0111416\|PMID:10498683
Biological Process	GO:0007294	germarium-derived oocyte fate determination	FBgn0015754	Lis-1	IMP	Fly	FB:FBrf0112050
Biological Process	GO:0040035	hermaphrodite genitalia development	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00004895\|PMID:11685578
Biological Process	GO:0007626	locomotory behavior	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00004895\|PMID:11685578
Biological Process	GO:0000226	microtubule cytoskeleton organization and biogenesis	MGI:109520	Pafah1b1	IGI	Mouse	MGI:MGI:3588829\|PMID:16107726
Biological Process	GO:0007018	microtubule-based movement	FBgn0015754	Lis-1	ISS	Fly	FB:FBrf0132100\|PMID:10908588
Biological Process	GO:0007018	microtubule-based movement	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00024358\|PMID:15331665
Biological Process	GO:0007017	microtubule-based process	RGD:620331	Pafah1b1	ISS	Rat	RGD:1580655
Biological Process	GO:0007100	mitotic centrosome separation	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00024358\|PMID:15331665
Biological Process	GO:0016319	mushroom body development	FBgn0015754	Lis-1	IMP	Fly	FB:FBrf0131351\|PMID:11056531
Biological Process	GO:0007399	nervous system development	RGD:620331	Pafah1b1	ISS	Rat	RGD:1580655
Biological Process	GO:0007405	neuroblast proliferation	MGI:109520	Pafah1b1	IMP	Mouse	MGI:MGI:2651971\|PMID:12629176
Biological Process	GO:0001764	neuron migration	MGI:109520	Pafah1b1	IMP	Mouse	MGI:MGI:3052388\|PMID:15331402
Biological Process	GO:0001764	neuron migration	MGI:109520	Pafah1b1	IGI	Mouse	MGI:MGI:3588829\|PMID:16107726
Biological Process	GO:0001764	neuron migration	RGD:620331	Pafah1b1	IMP	Rat	RGD:1601501\|PMID:16144905
Biological Process	GO:0035046	pronuclear migration	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00004895\|PMID:11685578
Biological Process	GO:0035046	pronuclear migration	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00025054\|PMID:15791247
Biological Process	GO:0035046	pronuclear migration	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00024358\|PMID:15331665
Biological Process	GO:0050790	regulation of catalytic activity	FBgn0015754	Lis-1	ISS	Fly	FB:FBrf0105495
Biological Process	GO:0050790	regulation of catalytic activity	FBgn0015754	Lis-1	ISS	Fly	FB:FBrf0111489\|PMID:10471706
Biological Process	GO:0008090	retrograde axon cargo transport	MGI:109520	Pafah1b1	IDA	Mouse	MGI:MGI:1928566\|PMID:11163259
Biological Process	GO:0007165	signal transduction	RGD:620331	Pafah1b1	ISS	Rat	RGD:1580655
Biological Process	GO:0051225	spindle assembly	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00024358\|PMID:15331665
Biological Process	GO:0007051	spindle organization and biogenesis	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00024358\|PMID:15331665
Biological Process	GO:0017145	stem cell division	RGD:620331	Pafah1b1	IMP	Rat	RGD:1601501\|PMID:16144905
Biological Process	GO:0051932	synaptic transmission, GABAergic	WBGene00003047	lis-1	IMP	Worm	WB:WBPaper00028525\|PMID:16996038
Biological Process	GO:0047496	vesicle transport along microtubule	MGI:109520	Pafah1b1	IGI	Mouse	MGI:MGI:3588829\|PMID:16107726

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)