Compare GO annotations for HomoloGene:3785 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	P31749	AKT1_HUMAN	IPI	Human	PMID:7891724
Molecular Function	GO:0042802	identical protein binding	RGD:2081	Akt1	ISS	Rat	RGD:1580655
Molecular Function	GO:0016301	kinase activity	MGI:87986	Akt1	ISS	Mouse	MGI:MGI:3027417\|PMID:14749367
Molecular Function	GO:0005515	protein binding	MGI:87986	Akt1	ISS	Mouse	MGI:MGI:3027417\|PMID:14749367
Molecular Function	GO:0005515	protein binding	MGI:87986	Akt1	IPI	Mouse	MGI:MGI:3687885\|PMID:12791994
Molecular Function	GO:0005515	protein binding	MGI:87986	Akt1	IPI	Mouse	MGI:MGI:3690209\|PMID:16357133
Molecular Function	GO:0005515	protein binding	MGI:87986	Akt1	IPI	Mouse	MGI:MGI:3581096\|PMID:15753085
Molecular Function	GO:0005515	protein binding	RGD:2081	Akt1	IPI	Rat	RGD:1579942\|PMID:15120593
Molecular Function	GO:0005515	protein binding	RGD:2081	Akt1	IDA	Rat	RGD:632178\|PMID:12194869
Molecular Function	GO:0005515	protein binding	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Molecular Function	GO:0004672	protein kinase activity	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:3047434\|PMID:15192701
Molecular Function	GO:0004672	protein kinase activity	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:3028410\|PMID:14730361
Molecular Function	GO:0004672	protein kinase activity	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:3510060\|PMID:15010863
Molecular Function	GO:0004672	protein kinase activity	RGD:2081	Akt1	IDA	Rat	RGD:625444\|PMID:12084817
Molecular Function	GO:0004672	protein kinase activity	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Molecular Function	GO:0004674	protein serine/threonine kinase activity	P31749	AKT1_HUMAN	IDA	Human	PMID:16139227
Molecular Function	GO:0004674	protein serine/threonine kinase activity	P31749	AKT1_HUMAN	IDA	Human	PMID:11994271
Molecular Function	GO:0004674	protein serine/threonine kinase activity	RGD:2081	Akt1	ISS	Rat	RGD:1600115
Molecular Function	GO:0004674	protein serine/threonine kinase activity	WB:WP:CE15612	AKT-1	ISS	Worm	WB:WBPaper00003173\|PMID:9716402
Molecular Function	GO:0004674	protein serine/threonine kinase activity	WB:WP:CE05274	AKT-1	ISS	Worm	WB:WBPaper00003173\|PMID:9716402
Molecular Function	GO:0004674	protein serine/threonine kinase activity	WB:WP:CE31304	AKT-1	ISS	Worm	WB:WBPaper00003173\|PMID:9716402
Molecular Function	GO:0004713	protein-tyrosine kinase activity	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Molecular Function	GO:0004702	receptor signaling protein serine/threonine kinase activity	RGD:2081	Akt1	ISS	Rat	RGD:1580655
Cellular Component	GO:0005737	cytoplasm	P31749	AKT1_HUMAN	ISS	Human	UniProt:P31749
Cellular Component	GO:0005737	cytoplasm	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:2387238\|PMID:12124386
Cellular Component	GO:0005737	cytoplasm	RGD:2081	Akt1	IDA	Rat	RGD:632178\|PMID:12194869
Cellular Component	GO:0005737	cytoplasm	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Cellular Component	GO:0005622	intracellular	WB:WP:CE15612	AKT-1	IDA	Worm	WB:WBPaper00003173\|PMID:9716402
Cellular Component	GO:0005622	intracellular	WB:WP:CE05274	AKT-1	IDA	Worm	WB:WBPaper00003173\|PMID:9716402
Cellular Component	GO:0005622	intracellular	WB:WP:CE31304	AKT-1	IDA	Worm	WB:WBPaper00003173\|PMID:9716402
Cellular Component	GO:0030027	lamellipodium	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:2675770\|PMID:12944902
Cellular Component	GO:0030027	lamellipodium	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Cellular Component	GO:0005886	plasma membrane	P31749	AKT1_HUMAN	IDA	Human	PMID:14749367
Cellular Component	GO:0005886	plasma membrane	MGI:87986	Akt1	ISS	Mouse	MGI:MGI:3027417\|PMID:14749367
Cellular Component	GO:0005819	spindle	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:3056244\|PMID:15509711
Cellular Component	GO:0005819	spindle	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Biological Process	GO:0006924	activated T cell apoptosis	P31749	AKT1_HUMAN	IMP	Human	PMID:14749367
Biological Process	GO:0006924	activated T cell apoptosis	MGI:87986	Akt1	ISS	Mouse	MGI:MGI:3027417\|PMID:14749367
Biological Process	GO:0042640	anagen	MGI:87986	Akt1	IMP	Mouse	MGI:MGI:3531621\|PMID:15713628
Biological Process	GO:0042640	anagen	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Biological Process	GO:0006916	anti-apoptosis	RGD:2081	Akt1	IMP	Rat	RGD:632178\|PMID:12194869
Biological Process	GO:0006916	anti-apoptosis	RGD:2081	Akt1	ISS	Rat	RGD:1580655
Biological Process	GO:0006915	apoptosis	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:2387238\|PMID:12124386
Biological Process	GO:0006915	apoptosis	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Biological Process	GO:0008637	apoptotic mitochondrial changes	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:2669068\|PMID:12869584
Biological Process	GO:0008637	apoptotic mitochondrial changes	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Biological Process	GO:0001568	blood vessel development	MGI:87986	Akt1	IMP	Mouse	MGI:MGI:2673047\|PMID:12783884
Biological Process	GO:0030030	cell projection organization and biogenesis	MGI:87986	Akt1	ISS	Mouse	MGI:MGI:3610880\|PMID:16286931
Biological Process	GO:0040024	dauer larval development	WBGene00000102	akt-1	IMP	Worm	WB:WBPaper00013413\|PMID:15068796
Biological Process	GO:0008340	determination of adult life span	WBGene00000102	akt-1	IMP	Worm	WB:WBPaper00013413\|PMID:15068796
Biological Process	GO:0008340	determination of adult life span	WBGene00000102	akt-1	IMP	Worm	WB:WBPaper00003872\|PMID:10638522
Biological Process	GO:0007186	G-protein coupled receptor protein signaling pathway	RGD:2081	Akt1	ISS	Rat	RGD:1580655
Biological Process	GO:0007281	germ cell development	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:2384228\|PMID:12140361
Biological Process	GO:0007281	germ cell development	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Biological Process	GO:0015758	glucose transport	MGI:87986	Akt1	IMP	Mouse	MGI:MGI:3687709\|PMID:9415393
Biological Process	GO:0005978	glycogen biosynthetic process	RGD:2081	Akt1	IMP	Rat	RGD:null
Biological Process	GO:0005977	glycogen metabolic process	MGI:87986	Akt1	IMP	Mouse	MGI:MGI:2673047\|PMID:12783884
Biological Process	GO:0006954	inflammatory response	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:3028410\|PMID:14730361
Biological Process	GO:0006954	inflammatory response	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Biological Process	GO:0008286	insulin receptor signaling pathway	P31749	AKT1_HUMAN	IMP	Human	PMID:8978681
Biological Process	GO:0008286	insulin receptor signaling pathway	MGI:87986	Akt1	IMP	Mouse	MGI:MGI:3687709\|PMID:9415393
Biological Process	GO:0008286	insulin receptor signaling pathway	MGI:87986	Akt1	IMP	Mouse	MGI:MGI:3688072\|PMID:11282895
Biological Process	GO:0008286	insulin receptor signaling pathway	RGD:2081	Akt1	ISS	Rat	RGD:1580655
Biological Process	GO:0008286	insulin receptor signaling pathway	RGD:2081	Akt1	ISS	Rat	RGD:1600115
Biological Process	GO:0008286	insulin receptor signaling pathway	RGD:2081	Akt1	IMP	Rat	RGD:null
Biological Process	GO:0008286	insulin receptor signaling pathway	WBGene00000102	akt-1	IMP	Worm	WB:WBPaper00003173\|PMID:9716402
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	P31749	AKT1_HUMAN	IMP	Human	PMID:8978681
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	RGD:2081	Akt1	ISS	Rat	RGD:1580655
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	RGD:2081	Akt1	ISS	Rat	RGD:1600115
Biological Process	GO:0007242	intracellular signaling cascade	P31749	AKT1_HUMAN	IDA	Human	PMID:14749367
Biological Process	GO:0007242	intracellular signaling cascade	MGI:87986	Akt1	ISS	Mouse	MGI:MGI:3027417\|PMID:14749367
Biological Process	GO:0043066	negative regulation of apoptosis	MGI:87986	Akt1	IMP	Mouse	MGI:MGI:3688072\|PMID:11282895
Biological Process	GO:0043066	negative regulation of apoptosis	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Biological Process	GO:0045792	negative regulation of cell size	MGI:87986	Akt1	ISS	Mouse	MGI:MGI:3610880\|PMID:16286931
Biological Process	GO:0006809	nitric oxide biosynthetic process	RGD:2081	Akt1	ISS	Rat	RGD:1580655
Biological Process	GO:0018105	peptidyl-serine phosphorylation	P31749	AKT1_HUMAN	IDA	Human	PMID:16139227
Biological Process	GO:0001890	placenta development	MGI:87986	Akt1	IMP	Mouse	MGI:MGI:2673047\|PMID:12783884
Biological Process	GO:0040018	positive regulation of body size	MGI:87986	Akt1	IMP	Mouse	MGI:MGI:2673047\|PMID:12783884
Biological Process	GO:0030307	positive regulation of cell growth	RGD:2081	Akt1	IDA	Rat	RGD:625444\|PMID:12084817
Biological Process	GO:0006468	protein amino acid phosphorylation	MGI:87986	Akt1	ISS	Mouse	MGI:MGI:3027417\|PMID:14749367
Biological Process	GO:0006468	protein amino acid phosphorylation	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:2384368\|PMID:12145204
Biological Process	GO:0006468	protein amino acid phosphorylation	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:3047434\|PMID:15192701
Biological Process	GO:0006468	protein amino acid phosphorylation	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:3028410\|PMID:14730361
Biological Process	GO:0006468	protein amino acid phosphorylation	RGD:2081	Akt1	IDA	Rat	RGD:625444\|PMID:12084817
Biological Process	GO:0006468	protein amino acid phosphorylation	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Biological Process	GO:0006468	protein amino acid phosphorylation	RGD:2081	Akt1	ISS	Rat	RGD:1580655
Biological Process	GO:0006468	protein amino acid phosphorylation	RGD:2081	Akt1	ISS	Rat	RGD:1600115
Biological Process	GO:0006468	protein amino acid phosphorylation	WB:WP:CE15612	AKT-1	ISS	Worm	WB:WBPaper00003173\|PMID:9716402
Biological Process	GO:0006468	protein amino acid phosphorylation	WB:WP:CE05274	AKT-1	ISS	Worm	WB:WBPaper00003173\|PMID:9716402
Biological Process	GO:0006468	protein amino acid phosphorylation	WB:WP:CE31304	AKT-1	ISS	Worm	WB:WBPaper00003173\|PMID:9716402
Biological Process	GO:0030163	protein catabolic process	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:2384368\|PMID:12145204
Biological Process	GO:0030163	protein catabolic process	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Biological Process	GO:0000060	protein import into nucleus, translocation	P31749	AKT1_HUMAN	IMP	Human	PMID:16280327
Biological Process	GO:0043491	protein kinase B signaling cascade	MGI:87986	Akt1	IGI	Mouse	MGI:MGI:3050929\|PMID:15249583
Biological Process	GO:0016567	protein ubiquitination	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:2384368\|PMID:12145204
Biological Process	GO:0016567	protein ubiquitination	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Biological Process	GO:0030334	regulation of cell migration	RGD:2081	Akt1	IMP	Rat	RGD:1625249\|PMID:17109063
Biological Process	GO:0045884	regulation of survival gene product activity	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:3028410\|PMID:14730361
Biological Process	GO:0045884	regulation of survival gene product activity	RGD:2081	Akt1	ISS	Rat	RGD:1580654
Biological Process	GO:0009408	response to heat	RGD:2081	Akt1	ISS	Rat	RGD:1580655
Biological Process	GO:0009725	response to hormone stimulus	MGI:87986	Akt1	IDA	Mouse	MGI:MGI:3690209\|PMID:16357133
Biological Process	GO:0007165	signal transduction	RGD:2081	Akt1	IDA	Rat	RGD:625444\|PMID:12084817
Biological Process	GO:0007165	signal transduction	RGD:2081	Akt1	ISS	Rat	RGD:1580655

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)