Compare GO annotations for HomoloGene:4115 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0004930	G-protein coupled receptor activity	FBgn0003444	smo	ISS	Fly	FB:FBrf0089582\|PMID:8706127
Molecular Function	GO:0005515	protein binding	RGD:3726	Smo	ISS	Rat	RGD:1580655
Molecular Function	GO:0005515	protein binding	FBgn0003444	smo	IPI	Fly	FB:FBrf0167606\|PMID:14597665
Molecular Function	GO:0005515	protein binding	FBgn0003444	smo	IPI	Fly	FB:FBrf0179063\|PMID:14614827
Molecular Function	GO:0004872	receptor activity	RGD:3726	Smo	ISS	Rat	RGD:1580655
Molecular Function	GO:0004888	transmembrane receptor activity	FBgn0003444	smo	ISS	Fly	FB:FBrf0129744\|PMID:10908591
Cellular Component	GO:0043025	cell soma	RGD:3726	Smo	IDA	Rat	RGD:1580344\|PMID:15356205
Cellular Component	GO:0005929	cilium	MGI:108075	Smo	IDA	Mouse	MGI:MGI:3610248\|PMID:16229832
Cellular Component	GO:0005929	cilium	RGD:3726	Smo	ISS	Rat	RGD:1580654
Cellular Component	GO:0005929	cilium	ZDB-GENE-980526-89	smo	ISS	Zfin	ZFIN:ZDB-PUB-050907-11\|PMID:16136078
Cellular Component	GO:0016021	integral to membrane	RGD:3726	Smo	ISS	Rat	RGD:1580655
Cellular Component	GO:0016021	integral to membrane	FBgn0003444	smo	ISS	Fly	FB:FBrf0089582\|PMID:8706127
Cellular Component	GO:0016021	integral to membrane	FBgn0003444	smo	ISS	Fly	FB:FBrf0129744\|PMID:10908591
Cellular Component	GO:0016020	membrane	RGD:3726	Smo	ISS	Rat	RGD:1580654
Cellular Component	GO:0005624	membrane fraction	RGD:3726	Smo	ISS	Rat	RGD:1580655
Biological Process	GO:0007350	blastoderm segmentation	FBgn0003444	smo	IMP	Fly	FB:FBrf0089881\|PMID:8700230
Biological Process	GO:0001746	Bolwig's organ morphogenesis	FBgn0003444	smo	IMP	Fly	FB:FBrf0126773\|PMID:10704398
Biological Process	GO:0048468	cell development	MGI:108075	Smo	IMP	Mouse	MGI:MGI:2429663\|PMID:12403705
Biological Process	GO:0007417	central nervous system development	MGI:108075	Smo	IGI	Mouse	MGI:MGI:2445271\|PMID:12435628
Biological Process	GO:0007417	central nervous system development	RGD:3726	Smo	ISS	Rat	RGD:1580654
Biological Process	GO:0021953	central nervous system neuron differentiation	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3624182\|PMID:16571630
Biological Process	GO:0021696	cerebellar cortex morphogenesis	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3624180\|PMID:16571625
Biological Process	GO:0007368	determination of left/right symmetry	MGI:108075	Smo	IMP	Mouse	MGI:MGI:2389012\|PMID:12421714
Biological Process	GO:0007368	determination of left/right symmetry	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3577662\|PMID:15755804
Biological Process	GO:0007368	determination of left/right symmetry	RGD:3726	Smo	ISS	Rat	RGD:1580654
Biological Process	GO:0048589	developmental growth	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3624182\|PMID:16571630
Biological Process	GO:0009953	dorsal/ventral pattern formation	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3577662\|PMID:15755804
Biological Process	GO:0009953	dorsal/ventral pattern formation	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3624182\|PMID:16571630
Biological Process	GO:0009953	dorsal/ventral pattern formation	RGD:3726	Smo	ISS	Rat	RGD:1580654
Biological Process	GO:0031076	embryonic camera-type eye development	ZDB-GENE-980526-89	smo	IDA	Zfin	ZFIN:ZDB-PUB-050506-5\|PMID:15857917
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-050803-5\|PMID:16049113
Biological Process	GO:0009880	embryonic pattern specification	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-030805-6\|PMID:12889061
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-060412-2\|PMID:16580747
Biological Process	GO:0035270	endocrine system development	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-050426-1\|PMID:15728669
Biological Process	GO:0031017	exocrine pancreas development	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-060302-14\|PMID:16490192
Biological Process	GO:0048592	eye morphogenesis	FBgn0003444	smo	IMP	Fly	FB:FBrf0193969\|PMID:16651542
Biological Process	GO:0007455	eye-antennal disc morphogenesis	FBgn0003444	smo	IGI	Fly	FB:FBrf0146982\|PMID:11934850
Biological Process	GO:0021561	facial nerve development	RGD:3726	Smo	IEP	Rat	RGD:1580344\|PMID:15356205
Biological Process	GO:0021508	floor plate formation	ZDB-GENE-980526-89	smo	IGI	Zfin	ZFIN:ZDB-PUB-030115-17\|PMID:12508225
Biological Process	GO:0030900	forebrain development	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-041111-21\|PMID:15533825
Biological Process	GO:0003007	heart morphogenesis	MGI:108075	Smo	IGI	Mouse	MGI:MGI:3640718\|PMID:16687132
Biological Process	GO:0030902	hindbrain development	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-040804-3\|PMID:15281067
Biological Process	GO:0007275	multicellular organismal development	RGD:3726	Smo	ISS	Rat	RGD:1580655
Biological Process	GO:0042693	muscle cell fate commitment	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-041008-3\|PMID:15464578
Biological Process	GO:0042693	muscle cell fate commitment	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-050907-11\|PMID:16136078
Biological Process	GO:0007517	muscle development	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-041228-26\|PMID:15618520
Biological Process	GO:0030239	myofibril assembly	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-041202-3\|PMID:15572133
Biological Process	GO:0043066	negative regulation of apoptosis	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3624182\|PMID:16571630
Biological Process	GO:0043392	negative regulation of DNA binding	MGI:108075	Smo	IGI	Mouse	MGI:MGI:3611729\|PMID:16396903
Biological Process	GO:0043392	negative regulation of DNA binding	RGD:3726	Smo	ISS	Rat	RGD:1580654
Biological Process	GO:0007399	nervous system development	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-030919-9\|PMID:13129844
Biological Process	GO:0014033	neural crest cell differentiation	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-060313-5\|PMID:16502420
Biological Process	GO:0001755	neural crest cell migration	MGI:108075	Smo	IGI	Mouse	MGI:MGI:3640718\|PMID:16687132
Biological Process	GO:0001839	neural plate morphogenesis	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-060313-5\|PMID:16502420
Biological Process	GO:0031102	neurite regeneration	RGD:3726	Smo	IEP	Rat	RGD:1580344\|PMID:15356205
Biological Process	GO:0048663	neuron fate commitment	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-060313-5\|PMID:16502420
Biological Process	GO:0042475	odontogenesis (sensu Vertebrata)	MGI:108075	Smo	IMP	Mouse	MGI:MGI:2429663\|PMID:12403705
Biological Process	GO:0001649	osteoblast differentiation	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3036410\|PMID:14973297
Biological Process	GO:0001649	osteoblast differentiation	RGD:3726	Smo	ISS	Rat	RGD:1580654
Biological Process	GO:0031016	pancreas development	ZDB-GENE-980526-89	smo	IMP	Zfin	ZFIN:ZDB-PUB-050803-9\|PMID:16055112
Biological Process	GO:0007389	pattern specification process	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3040160\|PMID:15107405
Biological Process	GO:0007389	pattern specification process	RGD:3726	Smo	ISS	Rat	RGD:1580654
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:108075	Smo	IMP	Mouse	MGI:MGI:2429663\|PMID:12403705
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	MGI:108075	Smo	IGI	Mouse	MGI:MGI:3619284\|PMID:16543460
Biological Process	GO:0007346	regulation of progression through mitotic cell cycle	FBgn0003444	smo	IMP	Fly	FB:FBrf0135358\|PMID:11279500
Biological Process	GO:0009611	response to wounding	RGD:3726	Smo	IEP	Rat	RGD:1580344\|PMID:15356205
Biological Process	GO:0007165	signal transduction	FBgn0003444	smo	ISS	Fly	FB:FBrf0129744\|PMID:10908591
Biological Process	GO:0007224	smoothened signaling pathway	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3040160\|PMID:15107405
Biological Process	GO:0007224	smoothened signaling pathway	RGD:3726	Smo	ISS	Rat	RGD:704355\|PMID:9422511
Biological Process	GO:0007224	smoothened signaling pathway	RGD:3726	Smo	ISS	Rat	RGD:1580654
Biological Process	GO:0007224	smoothened signaling pathway	FBgn0003444	smo	IMP	Fly	FB:FBrf0090495\|PMID:8898207
Biological Process	GO:0007224	smoothened signaling pathway	FBgn0003444	smo	IMP	Fly	FB:FBrf0167606\|PMID:14597665
Biological Process	GO:0021938	smoothened signaling pathway in regulation of granule cell precursor cell proliferation	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3624180\|PMID:16571625
Biological Process	GO:0001570	vasculogenesis	MGI:108075	Smo	IMP	Mouse	MGI:MGI:3051693\|PMID:15294868
Biological Process	GO:0001570	vasculogenesis	RGD:3726	Smo	ISS	Rat	RGD:1580654

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)