Compare GO annotations for HomoloGene:4349 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0050660	FAD binding	RGD:1309952	Mthfr_predicted	IDA	Rat	RGD:1601423\|PMID:11730351
Molecular Function	GO:0004489	methylenetetrahydrofolate reductase (NADPH) activity	MGI:106639	Mthfr	IMP	Mouse	MGI:MGI:3510291\|PMID:15217352
Molecular Function	GO:0004489	methylenetetrahydrofolate reductase (NADPH) activity	RGD:1309952	Mthfr_predicted	ISS	Rat	RGD:1535021\|PMID:11933257
Molecular Function	GO:0004489	methylenetetrahydrofolate reductase (NADPH) activity	RGD:1309952	Mthfr_predicted	ISS	Rat	RGD:1580654
Molecular Function	GO:0004489	methylenetetrahydrofolate reductase (NADPH) activity	RGD:1309952	Mthfr_predicted	ISS	Rat	RGD:1580655
Molecular Function	GO:0004489	methylenetetrahydrofolate reductase (NADPH) activity	RGD:1309952	Mthfr_predicted	IDA	Rat	RGD:1601423\|PMID:11730351
Molecular Function	GO:0004489	methylenetetrahydrofolate reductase (NADPH) activity	S000003093	MET13	IDA	Yeast	SGD_REF:S000055171\|PMID:10600168
Molecular Function	GO:0004489	methylenetetrahydrofolate reductase (NADPH) activity	S000003093	MET13	ISS	Yeast	SGD_REF:S000042632\|PMID:8896269
Molecular Function	GO:0050661	NADP binding	RGD:1309952	Mthfr_predicted	IDA	Rat	RGD:1601423\|PMID:11730351
Molecular Function	GO:0005515	protein binding	P42898	MTHR_HUMAN	IPI	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	RGD:1309952	Mthfr_predicted	ISS	Rat	RGD:1580655
Molecular Function	GO:0003735	structural constituent of ribosome	S000003093	MET13	IDA	Yeast	SGD_REF:S000058441\|PMID:9151978
Cellular Component	GO:0005737	cytoplasm	S000003093	MET13	IDA	Yeast	SGD_REF:S000055171\|PMID:10600168
Cellular Component	GO:0005762	mitochondrial large ribosomal subunit	S000003093	MET13	IDA	Yeast	SGD_REF:S000058441\|PMID:9151978
Cellular Component	GO:0005739	mitochondrion	S000003093	MET13	IDA	Yeast	SGD_REF:S000075100\|PMID:14576278
Cellular Component	GO:0005739	mitochondrion	S000003093	MET13	IDA	Yeast	SGD_REF:S000117178\|PMID:16823961
Cellular Component	GO:0005625	soluble fraction	RGD:1309952	Mthfr_predicted	IDA	Rat	RGD:1601423\|PMID:11730351
Biological Process	GO:0006520	amino acid metabolic process	RGD:1309952	Mthfr_predicted	ISS	Rat	RGD:1580655
Biological Process	GO:0008015	circulation	RGD:1309952	Mthfr_predicted	ISS	Rat	RGD:1580655
Biological Process	GO:0009086	methionine biosynthetic process	MGI:106639	Mthfr	IMP	Mouse	MGI:MGI:3510291\|PMID:15217352
Biological Process	GO:0009086	methionine biosynthetic process	RGD:1309952	Mthfr_predicted	ISS	Rat	RGD:1580654
Biological Process	GO:0006555	methionine metabolic process	S000003093	MET13	IMP	Yeast	SGD_REF:S000048523\|PMID:10029993
Biological Process	GO:0040010	positive regulation of growth rate	WBGene00015512	C06A8.1	IMP	Worm	WB:WBPaper00005654\|PMID:12529635
Biological Process	GO:0040010	positive regulation of growth rate	WBGene00015512	C06A8.1	IMP	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0046653	tetrahydrofolate metabolic process	RGD:1309952	Mthfr_predicted	ISS	Rat	RGD:1535021\|PMID:11933257
Biological Process	GO:0046653	tetrahydrofolate metabolic process	RGD:1309952	Mthfr_predicted	IDA	Rat	RGD:1601423\|PMID:11730351
Biological Process	GO:0006412	translation	S000003093	MET13	IDA	Yeast	SGD_REF:S000058441\|PMID:9151978

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)