Compare GO annotations for HomoloGene:527 orthologs

A table of the annotations represented in this image is provided below.
Category ID Term DB Object DB Symbol Evidence Organism Reference
Molecular FunctionGO:0051434BH3 domain bindingP10415BCL2_HUMANIPIHumanPMID:9111042
Molecular FunctionGO:0042802identical protein bindingRGD:2199Bcl2ISSRatRGD:1580655
Molecular FunctionGO:0002020protease bindingP10415BCL2_HUMANIDAHumanPMID:10620603
Molecular FunctionGO:0005515protein bindingMGI:88138Bcl2IPIMouseMGI:MGI:3709531|PMID:17274640
Molecular FunctionGO:0005515protein bindingRGD:2199Bcl2ISSRatRGD:1580654
Molecular FunctionGO:0005515protein bindingRGD:2199Bcl2IPIRatRGD:1581919|PMID:15004018
Molecular FunctionGO:0005515protein bindingQ00709BCL2_CHICKISSChickenUniProt:Q00709
Molecular FunctionGO:0046982protein heterodimerization activityP10415BCL2_HUMANIPIHumanPMID:9111042
Molecular FunctionGO:0046982protein heterodimerization activityMGI:88138Bcl2IPIMouseMGI:MGI:1931634|PMID:11226327
Molecular FunctionGO:0042803protein homodimerization activityP10415BCL2_HUMANIDAHumanPMID:9111042
Cellular ComponentGO:0005737cytoplasmP10415BCL2_HUMANIDAHumanPMID:11530860
Cellular ComponentGO:0005737cytoplasmRGD:2199Bcl2IDARatRGD:1581915|PMID:15341589
Cellular ComponentGO:0005829cytosolMGI:88138Bcl2IDAMouseMGI:MGI:2385392|PMID:12050152
Cellular ComponentGO:0005829cytosolMGI:88138Bcl2IDAMouseMGI:MGI:2683362|PMID:14551195
Cellular ComponentGO:0005829cytosolRGD:2199Bcl2ISSRatRGD:1580654
Cellular ComponentGO:0005741mitochondrial outer membraneP10415BCL2_HUMANIDAHumanPMID:9027314
Cellular ComponentGO:0005741mitochondrial outer membraneRGD:2199Bcl2ISSRatRGD:1580655
Cellular ComponentGO:0005741mitochondrial outer membraneQ00709BCL2_CHICKISSChickenUniProt:Q00709
Cellular ComponentGO:0005739mitochondrionP10415BCL2_HUMANIDAHumanPMID:9027314
Cellular ComponentGO:0005739mitochondrionMGI:88138Bcl2IDAMouseMGI:MGI:2445910|PMID:12420306
Cellular ComponentGO:0005739mitochondrionRGD:2199Bcl2ISSRatRGD:1580654
Cellular ComponentGO:0005739mitochondrionRGD:2199Bcl2IDARatRGD:1581915|PMID:15341589
Cellular ComponentGO:0005739mitochondrionQ00709BCL2_CHICKISSChickenUniProt:Q00709
Cellular ComponentGO:0031965nuclear membraneP10415BCL2_HUMANIDAHumanPMID:1502141
Biological ProcessGO:0006916anti-apoptosisP10415BCL2_HUMANIDAHumanPMID:9027314
Biological ProcessGO:0006916anti-apoptosisP10415BCL2_HUMANIDAHumanPMID:11684014
Biological ProcessGO:0006916anti-apoptosisP10415BCL2_HUMANIDAHumanPMID:10620603
Biological ProcessGO:0006916anti-apoptosisP10415BCL2_HUMANIDAHumanPMID:10506221
Biological ProcessGO:0006916anti-apoptosisMGI:88138Bcl2IDAMouseMGI:MGI:1203837|PMID:9560217
Biological ProcessGO:0006916anti-apoptosisMGI:88138Bcl2IDAMouseMGI:MGI:2683362|PMID:14551195
Biological ProcessGO:0006916anti-apoptosisMGI:88138Bcl2IGIMouseMGI:MGI:2179928|PMID:12082633
Biological ProcessGO:0006916anti-apoptosisRGD:2199Bcl2IDARatRGD:70671|PMID:11879647
Biological ProcessGO:0006916anti-apoptosisRGD:2199Bcl2ISSRatRGD:1580654
Biological ProcessGO:0006916anti-apoptosisRGD:2199Bcl2ISSRatRGD:1580655
Biological ProcessGO:0006916anti-apoptosisRGD:2199Bcl2IMPRatRGD:1581919|PMID:15004018
Biological ProcessGO:0006916anti-apoptosisQ00709BCL2_CHICKISSChickenUniProt:Q00709
Biological ProcessGO:0006915apoptosisMGI:88138Bcl2IDAMouseMGI:MGI:67275|PMID:8358790
Biological ProcessGO:0006915apoptosisRGD:2199Bcl2ISSRatRGD:1580654
Biological ProcessGO:0051607defense response to virusP10415BCL2_HUMANIDAHumanPMID:10620603
Biological ProcessGO:0031069hair follicle morphogenesisMGI:88138Bcl2IMPMouseMGI:MGI:63353|PMID:8402909
Biological ProcessGO:0006959humoral immune responseRGD:2199Bcl2ISSRatRGD:1580655
Biological ProcessGO:0043066negative regulation of apoptosisMGI:88138Bcl2IDAMouseMGI:MGI:3584078|PMID:15983387
Biological ProcessGO:0043066negative regulation of apoptosisRGD:2199Bcl2ISSRatRGD:1580654
Biological ProcessGO:0008285negative regulation of cell proliferationRGD:2199Bcl2ISSRatRGD:1580655
Biological ProcessGO:0032848negative regulation of cellular pH reductionP10415BCL2_HUMANIDAHumanPMID:10506221
Biological ProcessGO:0032848negative regulation of cellular pH reductionQ00709BCL2_CHICKISSChickenUniProt:Q00709
Biological ProcessGO:0043524negative regulation of neuron apoptosisMGI:88138Bcl2IDAMouseMGI:MGI:79659|PMID:8625820
Biological ProcessGO:0043473pigmentationMGI:88138Bcl2IMPMouseMGI:MGI:63353|PMID:8402909
Biological ProcessGO:0008284positive regulation of cell proliferationMGI:88138Bcl2IDAMouseMGI:MGI:2179155|PMID:11983915
Biological ProcessGO:0046902regulation of mitochondrial membrane permeabilityP10415BCL2_HUMANISSHumanPMID:9843949
Biological ProcessGO:0046902regulation of mitochondrial membrane permeabilityMGI:88138Bcl2IDAMouseMGI:MGI:3700463|PMID:9843949
Biological ProcessGO:0046902regulation of mitochondrial membrane permeabilityRGD:2199Bcl2ISSRatRGD:null
Biological ProcessGO:0046902regulation of mitochondrial membrane permeabilityQ00709BCL2_CHICKISSChickenUniProt:Q00709
Biological ProcessGO:0051881regulation of mitochondrial membrane potentialP10415BCL2_HUMANISSHumanPMID:9843949
Biological ProcessGO:0051881regulation of mitochondrial membrane potentialMGI:88138Bcl2IDAMouseMGI:MGI:3700463|PMID:9843949
Biological ProcessGO:0051881regulation of mitochondrial membrane potentialRGD:2199Bcl2ISSRatRGD:null
Biological ProcessGO:0051881regulation of mitochondrial membrane potentialQ00709BCL2_CHICKISSChickenUniProt:Q00709
Biological ProcessGO:0000074regulation of progression through cell cycleP10415BCL2_HUMANIDAHumanPMID:10848600
Biological ProcessGO:0000074regulation of progression through cell cycleRGD:2199Bcl2ISSRatRGD:1580655
Biological ProcessGO:0000074regulation of progression through cell cycleQ00709BCL2_CHICKISSChickenUniProt:Q00709
Biological ProcessGO:0043497regulation of protein heterodimerizationP10415BCL2_HUMANIDAHumanPMID:9111042
Biological ProcessGO:0043496regulation of protein homodimerizationP10415BCL2_HUMANIDAHumanPMID:9111042
Biological ProcessGO:0045069regulation of viral genome replicationMGI:88138Bcl2IDAMouseMGI:MGI:3700400|PMID:16950491
Biological ProcessGO:0001836release of cytochrome c from mitochondriaMGI:88138Bcl2IDAMouseMGI:MGI:3700463|PMID:9843949
Biological ProcessGO:0001836release of cytochrome c from mitochondriaRGD:2199Bcl2ISSRatRGD:1580654
Biological ProcessGO:0001836release of cytochrome c from mitochondriaRGD:2199Bcl2ISSRatRGD:1580655
Biological ProcessGO:0001836release of cytochrome c from mitochondriaRGD:2199Bcl2ISSRatRGD:null
Biological ProcessGO:0001836release of cytochrome c from mitochondriaQ00709BCL2_CHICKISSChickenUniProt:Q00709
Biological ProcessGO:0031000response to caffeineRGD:2199Bcl2IEPRatRGD:1599474|PMID:17236787
Biological ProcessGO:0043627response to estrogen stimulusRGD:2199Bcl2IEPRatRGD:1599488|PMID:16084662
Biological ProcessGO:0045471response to ethanolRGD:2199Bcl2IEPRatRGD:1599492|PMID:15469889
Biological ProcessGO:0009408response to heatRGD:2199Bcl2IEPRatRGD:1599475|PMID:17131910
Biological ProcessGO:0001666response to hypoxiaRGD:2199Bcl2IEPRatRGD:1599476|PMID:16445580
Biological ProcessGO:0010035response to inorganic substanceRGD:2199Bcl2IEPRatRGD:1599485|PMID:16256253
Biological ProcessGO:0010039response to iron ionP10415BCL2_HUMANIDAHumanPMID:11264898
Biological ProcessGO:0035094response to nicotineP10415BCL2_HUMANIDAHumanPMID:12421819
Biological ProcessGO:0035094response to nicotineRGD:2199Bcl2IEPRatRGD:1599493|PMID:15332118
Biological ProcessGO:0007584response to nutrientRGD:2199Bcl2IEPRatRGD:1599487|PMID:16216918
Biological ProcessGO:0010033response to organic substanceRGD:2199Bcl2IEPRatRGD:1599486|PMID:16249675
Biological ProcessGO:0043434response to peptide hormone stimulusRGD:2199Bcl2IEPRatRGD:1599489|PMID:15686664
Biological ProcessGO:0009636response to toxinP10415BCL2_HUMANIDAHumanPMID:16307838

Gene Ontology Evidence Code Abbreviations:

  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Not recorded (appears in some legacy annotations)