Compare GO annotations for HomoloGene:55440 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0005524	ATP binding	P35557	HXK4_HUMAN	IDA	Human	PMID:16173921
Molecular Function	GO:0005524	ATP binding	P35557	HXK4_HUMAN	IDA	Human	PMID:8446612
Molecular Function	GO:0005524	ATP binding	P35557	HXK4_HUMAN	IDA	Human	PMID:12941786
Molecular Function	GO:0005524	ATP binding	RGD:2670	Gck	ISS	Rat	RGD:728785\|PMID:2909525
Molecular Function	GO:0008865	fructokinase activity	gene:3355468	ATHXK1	IDA	Tair	TAIR:Publication:1357\|PMID:10402427
Molecular Function	GO:0004340	glucokinase activity	P35557	HXK4_HUMAN	IDA	Human	PMID:16173921
Molecular Function	GO:0004340	glucokinase activity	P35557	HXK4_HUMAN	IDA	Human	PMID:12941786
Molecular Function	GO:0004340	glucokinase activity	P35557	HXK4_HUMAN	IDA	Human	PMID:8446612
Molecular Function	GO:0004340	glucokinase activity	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:1099128\|PMID:9357804
Molecular Function	GO:0004340	glucokinase activity	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:3630095\|PMID:7510884
Molecular Function	GO:0004340	glucokinase activity	MGI:1270854	Gck	IDA	Mouse	MGI:MGI:54301\|PMID:141272
Molecular Function	GO:0004340	glucokinase activity	MGI:1270854	Gck	IDA	Mouse	MGI:MGI:56520\|PMID:3931624
Molecular Function	GO:0004340	glucokinase activity	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:76298\|PMID:7665557
Molecular Function	GO:0004340	glucokinase activity	MGI:1270854	Gck	IDA	Mouse	MGI:MGI:3691164\|PMID:9873043
Molecular Function	GO:0004340	glucokinase activity	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:76949\|PMID:7556622
Molecular Function	GO:0004340	glucokinase activity	RGD:2670	Gck	IDA	Rat	RGD:628440\|PMID:11250924
Molecular Function	GO:0004340	glucokinase activity	RGD:2670	Gck	ISS	Rat	RGD:1580654
Molecular Function	GO:0004340	glucokinase activity	RGD:2670	Gck	ISS	Rat	RGD:1580655
Molecular Function	GO:0004340	glucokinase activity	RGD:2670	Gck	IDA	Rat	RGD:1582633\|PMID:15138155
Molecular Function	GO:0004340	glucokinase activity	gene:3355468	ATHXK1	IDA	Tair	TAIR:Publication:501681937\|PMID:11851922
Molecular Function	GO:0004340	glucokinase activity	gene:3355468	ATHXK1	IDA	Tair	TAIR:Publication:1357\|PMID:10402427
Molecular Function	GO:0005536	glucose binding	P35557	HXK4_HUMAN	IDA	Human	PMID:16173921
Molecular Function	GO:0005536	glucose binding	P35557	HXK4_HUMAN	IDA	Human	PMID:12941786
Molecular Function	GO:0005536	glucose binding	P35557	HXK4_HUMAN	IDA	Human	PMID:8446612
Molecular Function	GO:0005536	glucose binding	RGD:2670	Gck	ISS	Rat	RGD:728785\|PMID:2909525
Molecular Function	GO:0005536	glucose binding	RGD:2670	Gck	IDA	Rat	RGD:1582633\|PMID:15138155
Molecular Function	GO:0004396	hexokinase activity	FBgn0001187	Hex-C	IDA	Fly	FB:FBrf0035134\|PMID:6768723
Molecular Function	GO:0004396	hexokinase activity	FBgn0001187	Hex-C	ISS	Fly	FB:FBrf0105495
Molecular Function	GO:0004396	hexokinase activity	gene:3355468	ATHXK1	IDA	Tair	TAIR:Publication:1357\|PMID:10402427
Molecular Function	GO:0004396	hexokinase activity	gene:3355468	ATHXK1	IDA	Tair	TAIR:Publication:501720900\|PMID:17324236
Molecular Function	GO:0005515	protein binding	P35557	HXK4_HUMAN	IPI	Human	PMID:16173921
Molecular Function	GO:0005515	protein binding	MGI:1270854	Gck	IPI	Mouse	MGI:MGI:2671672\|PMID:12931191
Molecular Function	GO:0005515	protein binding	RGD:2670	Gck	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	RGD:2670	Gck	ISS	Rat	RGD:1580655
Molecular Function	GO:0005515	protein binding	RGD:2670	Gck	IPI	Rat	RGD:1581880\|PMID:16186382
Molecular Function	GO:0005515	protein binding	RGD:2670	Gck	IMP	Rat	RGD:1581880\|PMID:16186382
Cellular Component	GO:0005737	cytoplasm	RGD:2670	Gck	IMP	Rat	RGD:1581880\|PMID:16186382
Cellular Component	GO:0005737	cytoplasm	RGD:2670	Gck	IDA	Rat	RGD:1582633\|PMID:15138155
Cellular Component	GO:0005737	cytoplasm	RGD:2670	Gck	IDA	Rat	RGD:1581879\|PMID:17028192
Cellular Component	GO:0005739	mitochondrion	MGI:1270854	Gck	IDA	Mouse	MGI:MGI:2671672\|PMID:12931191
Cellular Component	GO:0005739	mitochondrion	RGD:2670	Gck	ISS	Rat	RGD:1580654
Cellular Component	GO:0005634	nucleus	RGD:2670	Gck	IDA	Rat	RGD:1581880\|PMID:16186382
Cellular Component	GO:0005634	nucleus	RGD:2670	Gck	IDA	Rat	RGD:1582633\|PMID:15138155
Cellular Component	GO:0005634	nucleus	RGD:2670	Gck	IDA	Rat	RGD:1581879\|PMID:17028192
Cellular Component	GO:0005634	nucleus	gene:3355468	ATHXK1	IDA	Tair	TAIR:Publication:501720456\|PMID:17081979
Cellular Component	GO:0005625	soluble fraction	MGI:1270854	Gck	IDA	Mouse	MGI:MGI:54301\|PMID:141272
Cellular Component	GO:0005625	soluble fraction	RGD:2670	Gck	ISS	Rat	RGD:1580654
Biological Process	GO:0046835	carbohydrate phosphorylation	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:76949\|PMID:7556622
Biological Process	GO:0046835	carbohydrate phosphorylation	MGI:1270854	Gck	IDA	Mouse	MGI:MGI:54301\|PMID:141272
Biological Process	GO:0046835	carbohydrate phosphorylation	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:76298\|PMID:7665557
Biological Process	GO:0046835	carbohydrate phosphorylation	MGI:1270854	Gck	IDA	Mouse	MGI:MGI:56520\|PMID:3931624
Biological Process	GO:0046835	carbohydrate phosphorylation	RGD:2670	Gck	IDA	Rat	RGD:1582633\|PMID:15138155
Biological Process	GO:0001678	cell glucose homeostasis	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:76786\|PMID:7553875
Biological Process	GO:0001678	cell glucose homeostasis	RGD:2670	Gck	ISS	Rat	RGD:1580654
Biological Process	GO:0001678	cell glucose homeostasis	RGD:2670	Gck	IMP	Rat	RGD:1601297\|PMID:16443775
Biological Process	GO:0051594	detection of glucose	P35557	HXK4_HUMAN	IMP	Human	PMID:12941786
Biological Process	GO:0051156	glucose 6-phosphate metabolic process	RGD:2670	Gck	IDA	Rat	RGD:1582633\|PMID:15138155
Biological Process	GO:0042593	glucose homeostasis	P35557	HXK4_HUMAN	IMP	Human	PMID:8132752
Biological Process	GO:0042593	glucose homeostasis	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:1099128\|PMID:9357804
Biological Process	GO:0042593	glucose homeostasis	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:76949\|PMID:7556622
Biological Process	GO:0042593	glucose homeostasis	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:77846\|PMID:8530440
Biological Process	GO:0042593	glucose homeostasis	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:1327006\|PMID:9867845
Biological Process	GO:0010255	glucose mediated signaling	gene:3355468	ATHXK1	IMP	Tair	TAIR:Publication:501705864\|PMID:12690200
Biological Process	GO:0006006	glucose metabolic process	MGI:1270854	Gck	IDA	Mouse	MGI:MGI:56520\|PMID:3931624
Biological Process	GO:0006006	glucose metabolic process	MGI:1270854	Gck	IDA	Mouse	MGI:MGI:54301\|PMID:141272
Biological Process	GO:0006006	glucose metabolic process	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:1099128\|PMID:9357804
Biological Process	GO:0006006	glucose metabolic process	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:76298\|PMID:7665557
Biological Process	GO:0006006	glucose metabolic process	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:76949\|PMID:7556622
Biological Process	GO:0019320	hexose catabolic process	gene:3355468	ATHXK1	IDA	Tair	TAIR:Publication:1357\|PMID:10402427
Biological Process	GO:0006739	NADP metabolic process	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:3691164\|PMID:9873043
Biological Process	GO:0045721	negative regulation of gluconeogenesis	P35557	HXK4_HUMAN	IMP	Human	PMID:8878425
Biological Process	GO:0045725	positive regulation of glycogen biosynthetic process	P35557	HXK4_HUMAN	IMP	Human	PMID:8878425
Biological Process	GO:0032024	positive regulation of insulin secretion	P35557	HXK4_HUMAN	IMP	Human	PMID:8878425
Biological Process	GO:0032024	positive regulation of insulin secretion	P35557	HXK4_HUMAN	IMP	Human	PMID:8132752
Biological Process	GO:0032024	positive regulation of insulin secretion	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:76949\|PMID:7556622
Biological Process	GO:0012501	programmed cell death	gene:3355468	ATHXK1	IMP	Tair	TAIR:Publication:501719704\|PMID:16920781
Biological Process	GO:0050796	regulation of insulin secretion	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:77846\|PMID:8530440
Biological Process	GO:0050796	regulation of insulin secretion	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:85404\|PMID:8954920
Biological Process	GO:0043266	regulation of potassium ion transport	MGI:1270854	Gck	IMP	Mouse	MGI:MGI:1266883\|PMID:9662046
Biological Process	GO:0009749	response to glucose stimulus	RGD:2670	Gck	IEP	Rat	RGD:728812\|PMID:12086933
Biological Process	GO:0019932	second-messenger-mediated signaling	RGD:2670	Gck	IDA	Rat	RGD:628440\|PMID:11250924

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)