Compare GO annotations for HomoloGene:56383 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0003677	DNA binding	RGD:2244	Cacna1a	ISS	Rat	RGD:1580654
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1861319\|PMID:10908603
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2153687\|PMID:11718712
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2179541\|PMID:11344116
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	MGI:109482	Cacna1a	IGI	Mouse	MGI:MGI:2176015\|PMID:11756409
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2180460\|PMID:12065603
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3531609\|PMID:15548652
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3626144\|PMID:12040045
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3655539\|PMID:9742139
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2654957\|PMID:12624181
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3622595\|PMID:12401561
Molecular Function	GO:0005515	protein binding	O00555	CAC1A_HUMAN	IPI	Human	PMID:8692999
Molecular Function	GO:0005515	protein binding	MGI:109482	Cacna1a	IPI	Mouse	MGI:MGI:76430\|PMID:1370480
Molecular Function	GO:0005515	protein binding	MGI:109482	Cacna1a	IPI	Mouse	MGI:MGI:1345572\|PMID:10328888
Molecular Function	GO:0005515	protein binding	RGD:2244	Cacna1a	ISS	Rat	RGD:1580654
Molecular Function	GO:0019905	syntaxin binding	O00555	CAC1A_HUMAN	IDA	Human	PMID:8692999
Molecular Function	GO:0005245	voltage-gated calcium channel activity	O00555	CAC1A_HUMAN	ISS	Human	UniProt:O00555
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Q9NS88	Q9NS88_HUMAN	IDA	Human	PMID:10753886
Molecular Function	GO:0005245	voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3040168\|PMID:12827191
Molecular Function	GO:0005245	voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3619817\|PMID:12151514
Molecular Function	GO:0005245	voltage-gated calcium channel activity	MGI:109482	Cacna1a	IDA	Mouse	MGI:MGI:79428\|PMID:8632762
Molecular Function	GO:0005245	voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1261389\|PMID:9614225
Molecular Function	GO:0005245	voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1321414\|PMID:9857013
Molecular Function	GO:0005245	voltage-gated calcium channel activity	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1350870\|PMID:10611370
Molecular Function	GO:0005245	voltage-gated calcium channel activity	RGD:2244	Cacna1a	IDA	Rat	RGD:634678\|PMID:9593738
Molecular Function	GO:0005245	voltage-gated calcium channel activity	RGD:2244	Cacna1a	ISS	Rat	RGD:1580654
Molecular Function	GO:0005245	voltage-gated calcium channel activity	RGD:2244	Cacna1a	IDA	Rat	RGD:1582495\|PMID:16049183
Molecular Function	GO:0005245	voltage-gated calcium channel activity	FBgn0005563	cac	IMP	Fly	FB:FBrf0151379\|PMID:12122048
Cellular Component	GO:0016324	apical plasma membrane	FBgn0005563	cac	IDA	Fly	FB:FBrf0134446\|PMID:11208535
Cellular Component	GO:0016323	basolateral plasma membrane	FBgn0005563	cac	IDA	Fly	FB:FBrf0134446\|PMID:11208535
Cellular Component	GO:0042995	cell projection	O00555	CAC1A_HUMAN	IDA	Human	PMID:16595610
Cellular Component	GO:0043025	cell soma	MGI:109482	Cacna1a	IDA	Mouse	MGI:MGI:3055272\|PMID:15451373
Cellular Component	GO:0005737	cytoplasm	O00555	CAC1A_HUMAN	IDA	Human	PMID:16595610
Cellular Component	GO:0030425	dendrite	MGI:109482	Cacna1a	IDA	Mouse	MGI:MGI:3055272\|PMID:15451373
Cellular Component	GO:0016021	integral to membrane	RGD:2244	Cacna1a	ISS	Rat	RGD:1580654
Cellular Component	GO:0005634	nucleus	O00555	CAC1A_HUMAN	IDA	Human	PMID:16595610
Cellular Component	GO:0005634	nucleus	RGD:2244	Cacna1a	ISS	Rat	RGD:1580654
Cellular Component	GO:0043204	perikaryon	RGD:2244	Cacna1a	IDA	Rat	RGD:1582593\|PMID:16736476
Cellular Component	GO:0005886	plasma membrane	O00555	CAC1A_HUMAN	IDA	Human	PMID:16595610
Cellular Component	GO:0005886	plasma membrane	RGD:2244	Cacna1a	IMP	Rat	RGD:1358385\|PMID:14673106
Cellular Component	GO:0005886	plasma membrane	RGD:2244	Cacna1a	IDA	Rat	RGD:634678\|PMID:9593738
Cellular Component	GO:0005891	voltage-gated calcium channel complex	MGI:109482	Cacna1a	IDA	Mouse	MGI:MGI:1345572\|PMID:10328888
Cellular Component	GO:0005891	voltage-gated calcium channel complex	RGD:2244	Cacna1a	ISS	Rat	RGD:1580654
Cellular Component	GO:0005891	voltage-gated calcium channel complex	RGD:2244	Cacna1a	IDA	Rat	RGD:1582495\|PMID:16049183
Biological Process	GO:0008344	adult locomotory behavior	FBgn0005563	cac	IGI	Fly	FB:FBrf0127054\|PMID:10790395
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3664669\|PMID:16890369
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:48800\|PMID:13950100
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2150969\|PMID:11160387
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2179541\|PMID:11344116
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IGI	Mouse	MGI:MGI:1329569\|PMID:9882694
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1350870\|PMID:10611370
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:60955\|PMID:4799944
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:53718\|PMID:4941467
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:63040
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3622595\|PMID:12401561
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:83622\|PMID:8719807
Biological Process	GO:0007628	adult walking behavior	MGI:109482	Cacna1a	IGI	Mouse	MGI:MGI:83622\|PMID:8719807
Biological Process	GO:0048266	behavioral response to pain	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3664669\|PMID:16890369
Biological Process	GO:0006816	calcium ion transport	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3040168\|PMID:12827191
Biological Process	GO:0006816	calcium ion transport	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1261389\|PMID:9614225
Biological Process	GO:0006816	calcium ion transport	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1321414\|PMID:9857013
Biological Process	GO:0006816	calcium ion transport	RGD:2244	Cacna1a	IMP	Rat	RGD:1358385\|PMID:14673106
Biological Process	GO:0006816	calcium ion transport	RGD:2244	Cacna1a	IDA	Rat	RGD:634678\|PMID:9593738
Biological Process	GO:0006816	calcium ion transport	RGD:2244	Cacna1a	ISS	Rat	RGD:1580654
Biological Process	GO:0017156	calcium ion-dependent exocytosis	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2180460\|PMID:12065603
Biological Process	GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1353373\|PMID:10670432
Biological Process	GO:0008219	cell death	O00555	CAC1A_HUMAN	IDA	Human	PMID:16595610
Biological Process	GO:0016049	cell growth	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:62667\|PMID:1306163
Biological Process	GO:0030644	cellular chloride ion homeostasis	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:79685\|PMID:8565963
Biological Process	GO:0030644	cellular chloride ion homeostasis	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3610944\|PMID:10899223
Biological Process	GO:0021953	central nervous system neuron differentiation	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:55090\|PMID:6945603
Biological Process	GO:0021679	cerebellar molecular layer development	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:70349\|PMID:7697385
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:62667\|PMID:1306163
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:68980\|PMID:7834360
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1347769\|PMID:10630211
Biological Process	GO:0021680	cerebellar Purkinje cell layer development	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:62667\|PMID:1306163
Biological Process	GO:0021590	cerebellum maturation	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2179541\|PMID:11344116
Biological Process	GO:0007619	courtship behavior	FBgn0005563	cac	IMP	Fly	FB:FBrf0056527
Biological Process	GO:0048813	dendrite morphogenesis	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1337561\|PMID:10336181
Biological Process	GO:0048813	dendrite morphogenesis	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2150969\|PMID:11160387
Biological Process	GO:0048813	dendrite morphogenesis	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3042538\|PMID:14973254
Biological Process	GO:0007204	elevation of cytosolic calcium ion concentration	O00555	CAC1A_HUMAN	ISS	Human	UniProt:O00555
Biological Process	GO:0007204	elevation of cytosolic calcium ion concentration	Q9NS88	Q9NS88_HUMAN	IDA	Human	PMID:10753886
Biological Process	GO:0007204	elevation of cytosolic calcium ion concentration	MGI:109482	Cacna1a	IDA	Mouse	MGI:MGI:79428\|PMID:8632762
Biological Process	GO:0007204	elevation of cytosolic calcium ion concentration	RGD:2244	Cacna1a	ISS	Rat	RGD:1580654
Biological Process	GO:0042045	epithelial fluid transport	FBgn0005563	cac	IDA	Fly	FB:FBrf0134446\|PMID:11208535
Biological Process	GO:0042045	epithelial fluid transport	FBgn0005563	cac	IEP	Fly	FB:FBrf0134446\|PMID:11208535
Biological Process	GO:0014051	gamma-aminobutyric acid secretion	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1353373\|PMID:10670432
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:79685\|PMID:8565963
Biological Process	GO:0006006	glucose metabolic process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:708068\|PMID:8957685
Biological Process	GO:0042445	hormone metabolic process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:708068\|PMID:8957685
Biological Process	GO:0042445	hormone metabolic process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:63628\|PMID:8229069
Biological Process	GO:0007626	locomotory behavior	WBGene00006742	unc-2	IMP	Worm	WB:WBPaper00006272\|PMID:14675154
Biological Process	GO:0051899	membrane depolarization	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2153687\|PMID:11718712
Biological Process	GO:0051899	membrane depolarization	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:66121\|PMID:8158221
Biological Process	GO:0051899	membrane depolarization	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1861319\|PMID:10908603
Biological Process	GO:0050883	musculoskeletal movement, spinal reflex action	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2153687\|PMID:11718712
Biological Process	GO:0032353	negative regulation of hormone biosynthetic process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3652432\|PMID:11182254
Biological Process	GO:0043524	negative regulation of neuron apoptosis	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:53718\|PMID:4941467
Biological Process	GO:0043524	negative regulation of neuron apoptosis	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:84024\|PMID:8929530
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	WBGene00006742	unc-2	IGI	Worm	WB:WBPaper00006272\|PMID:14675154
Biological Process	GO:0007270	nerve-nerve synaptic transmission	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3619286\|PMID:16540584
Biological Process	GO:0050877	neurological process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:55989\|PMID:6462226
Biological Process	GO:0050877	neurological process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:52122\|PMID:1486501
Biological Process	GO:0050905	neuromuscular process	MGI:109482	Cacna1a	IGI	Mouse	MGI:MGI:1347769\|PMID:10630211
Biological Process	GO:0050905	neuromuscular process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2179541\|PMID:11344116
Biological Process	GO:0007274	neuromuscular synaptic transmission	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3606714\|PMID:10686170
Biological Process	GO:0042133	neurotransmitter metabolic process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:55028\|PMID:6167317
Biological Process	GO:0042133	neurotransmitter metabolic process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:49169\|PMID:1686215
Biological Process	GO:0042133	neurotransmitter metabolic process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:62875\|PMID:8100981
Biological Process	GO:0045887	positive regulation of synaptic growth at neuromuscular junction	FBgn0005563	cac	IMP	Fly	FB:FBrf0174769\|PMID:12896973
Biological Process	GO:0043113	receptor clustering	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2654957\|PMID:12624181
Biological Process	GO:0014056	regulation of acetylcholine secretion	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2654957\|PMID:12624181
Biological Process	GO:0014056	regulation of acetylcholine secretion	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3606714\|PMID:10686170
Biological Process	GO:0050770	regulation of axonogenesis	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:54631\|PMID:572084
Biological Process	GO:0050885	regulation of balance	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:60955\|PMID:4799944
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	MGI:109482	Cacna1a	IDA	Mouse	MGI:MGI:79428\|PMID:8632762
Biological Process	GO:0042391	regulation of membrane potential	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3619817\|PMID:12151514
Biological Process	GO:0042391	regulation of membrane potential	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:52137\|PMID:1355109
Biological Process	GO:0042391	regulation of membrane potential	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:49712\|PMID:1572065
Biological Process	GO:0042391	regulation of membrane potential	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1261389\|PMID:9614225
Biological Process	GO:0042391	regulation of membrane potential	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1321414\|PMID:9857013
Biological Process	GO:0042391	regulation of membrane potential	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1353373\|PMID:10670432
Biological Process	GO:0042391	regulation of membrane potential	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3622595\|PMID:12401561
Biological Process	GO:0001505	regulation of neurotransmitter levels	WBGene00006742	unc-2	IMP	Worm	WB:WBPaper00006272\|PMID:14675154
Biological Process	GO:0006355	regulation of transcription, DNA-dependent	RGD:2244	Cacna1a	ISS	Rat	RGD:1580654
Biological Process	GO:0009408	response to heat	WBGene00006742	unc-2	IMP	Worm	WB:WBPaper00006272\|PMID:14675154
Biological Process	GO:0048265	response to pain	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:2153687\|PMID:11718712
Biological Process	GO:0042594	response to starvation	WBGene00006742	unc-2	IMP	Worm	WB:WBPaper00006272\|PMID:14675154
Biological Process	GO:0060024	rhythmic synaptic transmission	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3620292\|PMID:16474392
Biological Process	GO:0000096	sulfur amino acid metabolic process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:60450\|PMID:1485534
Biological Process	GO:0007268	synaptic transmission	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1350870\|PMID:10611370
Biological Process	GO:0007268	synaptic transmission	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3531609\|PMID:15548652
Biological Process	GO:0007268	synaptic transmission	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3626144\|PMID:12040045
Biological Process	GO:0007268	synaptic transmission	RGD:2244	Cacna1a	IMP	Rat	RGD:1358385\|PMID:14673106
Biological Process	GO:0035249	synaptic transmission, glutamatergic	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1340444\|PMID:10322048
Biological Process	GO:0035249	synaptic transmission, glutamatergic	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3042538\|PMID:14973254
Biological Process	GO:0007416	synaptogenesis	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:1337561\|PMID:10336181
Biological Process	GO:0007416	synaptogenesis	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:3042538\|PMID:14973254
Biological Process	GO:0042403	thyroid hormone metabolic process	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:85368
Biological Process	GO:0019226	transmission of nerve impulse	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:49712\|PMID:1572065
Biological Process	GO:0019226	transmission of nerve impulse	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:51705\|PMID:1469420
Biological Process	GO:0019226	transmission of nerve impulse	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:52137\|PMID:1355109
Biological Process	GO:0021750	vestibular nucleus development	MGI:109482	Cacna1a	IMP	Mouse	MGI:MGI:77774\|PMID:8719615

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)