Compare GO annotations for HomoloGene:564 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0003869	4-nitrophenylphosphatase activity	MGI:88105	Atp1a1	IMP	Mouse	MGI:MGI:1337471\|PMID:10360172
Molecular Function	GO:0043531	ADP binding	RGD:2167	Atp1a1	IDA	Rat	RGD:1579857\|PMID:12730684
Molecular Function	GO:0005524	ATP binding	RGD:2167	Atp1a1	IDA	Rat	RGD:1579857\|PMID:12730684
Molecular Function	GO:0005524	ATP binding	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Molecular Function	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Molecular Function	GO:0016787	hydrolase activity	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Molecular Function	GO:0030955	potassium ion binding	RGD:2167	Atp1a1	IDA	Rat	RGD:1579784\|PMID:16269407
Molecular Function	GO:0005515	protein binding	P05023	AT1A1_HUMAN	IPI	Human	PMID:11027149
Molecular Function	GO:0005515	protein binding	P05023	AT1A1_HUMAN	IPI	Human	PMID:15671290
Molecular Function	GO:0005515	protein binding	MGI:88105	Atp1a1	IPI	Mouse	MGI:MGI:3525392\|PMID:15485817
Molecular Function	GO:0005515	protein binding	RGD:2167	Atp1a1	IPI	Rat	RGD:631775\|PMID:12093728
Molecular Function	GO:0005515	protein binding	RGD:2167	Atp1a1	ISS	Rat	RGD:1580655
Molecular Function	GO:0005515	protein binding	RGD:2167	Atp1a1	IPI	Rat	RGD:1598988\|PMID:16373350
Molecular Function	GO:0019904	protein domain specific binding	RGD:2167	Atp1a1	IPI	Rat	RGD:1579784\|PMID:16269407
Molecular Function	GO:0031402	sodium ion binding	RGD:2167	Atp1a1	IDA	Rat	RGD:1579784\|PMID:16269407
Molecular Function	GO:0005391	sodium:potassium-exchanging ATPase activity	MGI:88105	Atp1a1	IMP	Mouse	MGI:MGI:1337471\|PMID:10360172
Molecular Function	GO:0005391	sodium:potassium-exchanging ATPase activity	MGI:88105	Atp1a1	IMP	Mouse	MGI:MGI:3525392\|PMID:15485817
Molecular Function	GO:0005391	sodium:potassium-exchanging ATPase activity	RGD:2167	Atp1a1	IDA	Rat	RGD:1581763\|PMID:16893515
Molecular Function	GO:0005391	sodium:potassium-exchanging ATPase activity	RGD:2167	Atp1a1	IDA	Rat	RGD:629542\|PMID:12531906
Molecular Function	GO:0005391	sodium:potassium-exchanging ATPase activity	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Molecular Function	GO:0005391	sodium:potassium-exchanging ATPase activity	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-031111-8\|PMID:14602677
Cellular Component	GO:0016323	basolateral plasma membrane	MGI:88105	Atp1a1	IDA	Mouse	MGI:MGI:66717\|PMID:8144700
Cellular Component	GO:0016323	basolateral plasma membrane	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Cellular Component	GO:0005768	endosome	RGD:2167	Atp1a1	IDA	Rat	RGD:1581763\|PMID:16893515
Cellular Component	GO:0016021	integral to membrane	P05023	AT1A1_HUMAN	ISS	Human	UniProt:P05023
Cellular Component	GO:0016021	integral to membrane	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Cellular Component	GO:0016021	integral to membrane	RGD:2167	Atp1a1	ISS	Rat	RGD:1600115
Cellular Component	GO:0016021	integral to membrane	P09572	AT1A1_CHICK	ISS	Chicken	UniProt:P09572
Cellular Component	GO:0005887	integral to plasma membrane	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Cellular Component	GO:0016020	membrane	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Cellular Component	GO:0005624	membrane fraction	RGD:2167	Atp1a1	IDA	Rat	RGD:1581763\|PMID:16893515
Cellular Component	GO:0005624	membrane fraction	RGD:2167	Atp1a1	ISS	Rat	RGD:1580655
Cellular Component	GO:0005792	microsome	MGI:88105	Atp1a1	IDA	Mouse	MGI:MGI:2151725\|PMID:11557593
Cellular Component	GO:0005792	microsome	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Cellular Component	GO:0005886	plasma membrane	MGI:88105	Atp1a1	IDA	Mouse	MGI:MGI:1860042\|PMID:10837135
Cellular Component	GO:0005886	plasma membrane	MGI:88105	Atp1a1	IDA	Mouse	MGI:MGI:3703420\|PMID:10468580
Cellular Component	GO:0005886	plasma membrane	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Cellular Component	GO:0042383	sarcolemma	MGI:88105	Atp1a1	IDA	Mouse	MGI:MGI:3525392\|PMID:15485817
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	RGD:2167	Atp1a1	IDA	Rat	RGD:631775\|PMID:12093728
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	RGD:2167	Atp1a1	IDA	Rat	RGD:1581763\|PMID:16893515
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Biological Process	GO:0015991	ATP hydrolysis coupled proton transport	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Biological Process	GO:0008217	blood pressure regulation	MGI:88105	Atp1a1	IGI	Mouse	MGI:MGI:3608241\|PMID:16243970
Biological Process	GO:0007420	brain development	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-050328-1\|PMID:15788456
Biological Process	GO:0007420	brain development	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-031111-8\|PMID:14602677
Biological Process	GO:0035051	cardiac cell differentiation	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-031111-8\|PMID:14602677
Biological Process	GO:0035051	cardiac cell differentiation	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-040810-6\|PMID:15297381
Biological Process	GO:0002026	cardiac inotropy	MGI:88105	Atp1a1	IMP	Mouse	MGI:MGI:1337471\|PMID:10360172
Biological Process	GO:0002026	cardiac inotropy	MGI:88105	Atp1a1	IMP	Mouse	MGI:MGI:3525392\|PMID:15485817
Biological Process	GO:0006812	cation transport	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Biological Process	GO:0030641	cellular hydrogen ion homeostasis	P05023	AT1A1_HUMAN	ISS	Human	UniProt:P05023
Biological Process	GO:0030641	cellular hydrogen ion homeostasis	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Biological Process	GO:0030641	cellular hydrogen ion homeostasis	RGD:2167	Atp1a1	ISS	Rat	RGD:1600115
Biological Process	GO:0030641	cellular hydrogen ion homeostasis	P09572	AT1A1_CHICK	ISS	Chicken	UniProt:P09572
Biological Process	GO:0007368	determination of left/right symmetry	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-060424-7\|PMID:16628609
Biological Process	GO:0010172	embryonic body morphogenesis	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-031111-8\|PMID:14602677
Biological Process	GO:0035050	embryonic heart tube development	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-070210-8\|PMID:17227894
Biological Process	GO:0035050	embryonic heart tube development	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-031111-8\|PMID:14602677
Biological Process	GO:0008152	metabolic process	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Biological Process	GO:0030917	midbrain-hindbrain boundary development	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-060403-5\|PMID:16566913
Biological Process	GO:0031947	negative regulation of glucocorticoid biosynthetic process	MGI:88105	Atp1a1	IMP	Mouse	MGI:MGI:3696486\|PMID:17234593
Biological Process	GO:0045822	negative regulation of heart contraction	MGI:88105	Atp1a1	IMP	Mouse	MGI:MGI:3525392\|PMID:15485817
Biological Process	GO:0030916	otic vesicle formation	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-060403-5\|PMID:16566913
Biological Process	GO:0048840	otolith development	ZDB-GENE-001212-1	atp1a1	IMP	Zfin	ZFIN:ZDB-PUB-060403-5\|PMID:16566913
Biological Process	GO:0048840	otolith development	ZDB-GENE-001212-1	atp1a1	IGI	Zfin	ZFIN:ZDB-PUB-060403-5\|PMID:16566913
Biological Process	GO:0045823	positive regulation of heart contraction	MGI:88105	Atp1a1	IMP	Mouse	MGI:MGI:1337471\|PMID:10360172
Biological Process	GO:0045989	positive regulation of striated muscle contraction	MGI:88105	Atp1a1	IMP	Mouse	MGI:MGI:3688972\|PMID:11507009
Biological Process	GO:0010107	potassium ion import	RGD:2167	Atp1a1	IDA	Rat	RGD:629542\|PMID:12531906
Biological Process	GO:0006813	potassium ion transport	RGD:2167	Atp1a1	IDA	Rat	RGD:631775\|PMID:12093728
Biological Process	GO:0006813	potassium ion transport	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Biological Process	GO:0042493	response to drug	MGI:88105	Atp1a1	IMP	Mouse	MGI:MGI:3696486\|PMID:17234593
Biological Process	GO:0006814	sodium ion transport	RGD:2167	Atp1a1	IDA	Rat	RGD:631775\|PMID:12093728
Biological Process	GO:0006814	sodium ion transport	RGD:2167	Atp1a1	IDA	Rat	RGD:629542\|PMID:12531906
Biological Process	GO:0006814	sodium ion transport	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Biological Process	GO:0030317	sperm motility	P05023	AT1A1_HUMAN	ISS	Human	UniProt:P05023
Biological Process	GO:0030317	sperm motility	RGD:2167	Atp1a1	ISS	Rat	RGD:1580654
Biological Process	GO:0030317	sperm motility	RGD:2167	Atp1a1	ISS	Rat	RGD:1600115
Biological Process	GO:0030317	sperm motility	P09572	AT1A1_CHICK	ISS	Chicken	UniProt:P09572

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)