Compare GO annotations for HomoloGene:56556 orthologs

A table of the annotations represented in this image is provided below.
Category ID Term DB Object DB Symbol Evidence Organism Reference
Molecular FunctionGO:0019213deacetylase activityWB:WP:CE06302SIR-2.1IDAWormWB:WBPaper00024298|PMID:15254550
Molecular FunctionGO:0003677DNA bindingRGD:1308542Sirt1_predictedISSRatRGD:1580654
Molecular FunctionGO:0004407histone deacetylase activityFBgn0024291Sir2IDAFlyFB:FBrf0135765|PMID:11281647
Molecular FunctionGO:0004407histone deacetylase activityFBgn0024291Sir2IDAFlyFB:FBrf0190812|PMID:16137856
Molecular FunctionGO:0017136NAD-dependent histone deacetylase activityMGI:2135607Sirt1IDAMouseMGI:MGI:1891853|PMID:10693811
Molecular FunctionGO:0017136NAD-dependent histone deacetylase activityRGD:1308542Sirt1_predictedISSRatRGD:1580654
Molecular FunctionGO:0017136NAD-dependent histone deacetylase activityFBgn0024291Sir2ISSFlyFB:FBrf0105495
Molecular FunctionGO:0017136NAD-dependent histone deacetylase activityFBgn0024291Sir2IDAFlyFB:FBrf0147095|PMID:11812793
Molecular FunctionGO:0017136NAD-dependent histone deacetylase activityFBgn0024291Sir2IDAFlyFB:FBrf0148924|PMID:12086602
Molecular FunctionGO:0017136NAD-dependent histone deacetylase activityFBgn0024291Sir2IDAFlyFB:FBrf0155506|PMID:12524341
Molecular FunctionGO:0017136NAD-dependent histone deacetylase activityFBgn0024291Sir2IDAFlyFB:FBrf0180067|PMID:15498488
Molecular FunctionGO:0016564transcription repressor activityMGI:2135607Sirt1IDAMouseMGI:MGI:3522067|PMID:15381699
Molecular FunctionGO:0016564transcription repressor activityRGD:1308542Sirt1_predictedISSRatRGD:1580654
Cellular ComponentGO:0005677chromatin silencing complexRGD:1308542Sirt1_predictedISSRatRGD:1580654
Cellular ComponentGO:0005737cytoplasmFBgn0024291Sir2IDAFlyFB:FBrf0155506|PMID:12524341
Cellular ComponentGO:0005654nucleoplasmFBgn0024291Sir2IDAFlyFB:FBrf0190776|PMID:16219773
Cellular ComponentGO:0005634nucleusMGI:2135607Sirt1IDAMouseMGI:MGI:2447945|PMID:12482959
Cellular ComponentGO:0005634nucleusMGI:2135607Sirt1IDAMouseMGI:MGI:3522067|PMID:15381699
Cellular ComponentGO:0005634nucleusRGD:1308542Sirt1_predictedISSRatRGD:1580654
Cellular ComponentGO:0005634nucleusFBgn0024291Sir2IDAFlyFB:FBrf0155506|PMID:12524341
Biological ProcessGO:0006342chromatin silencingRGD:1308542Sirt1_predictedISSRatRGD:1580654
Biological ProcessGO:0006342chromatin silencingFBgn0024291Sir2IMPFlyFB:FBrf0190776|PMID:16219773
Biological ProcessGO:0008340determination of adult life spanFBgn0024291Sir2IMPFlyFB:FBrf0154651
Biological ProcessGO:0008340determination of adult life spanWBGene00004800sir-2.1IMPWormWB:WBPaper00024298|PMID:15254550
Biological ProcessGO:0016575histone deacetylationMGI:2135607Sirt1IDAMouseMGI:MGI:1891853|PMID:10693811
Biological ProcessGO:0016575histone deacetylationRGD:1308542Sirt1_predictedISSRatRGD:1580654
Biological ProcessGO:0016575histone deacetylationFBgn0024291Sir2IDAFlyFB:FBrf0147095|PMID:11812793
Biological ProcessGO:0016481negative regulation of transcriptionMGI:2135607Sirt1IDAMouseMGI:MGI:3522067|PMID:15381699
Biological ProcessGO:0016481negative regulation of transcriptionRGD:1308542Sirt1_predictedISSRatRGD:1580654
Biological ProcessGO:0001542ovulation from ovarian follicleMGI:2135607Sirt1IMPMouseMGI:MGI:2447945|PMID:12482959
Biological ProcessGO:0001542ovulation from ovarian follicleRGD:1308542Sirt1_predictedISSRatRGD:1580654
Biological ProcessGO:0006476protein amino acid deacetylationWB:WP:CE06302SIR-2.1IDAWormWB:WBPaper00024298|PMID:15254550
Biological ProcessGO:0035065regulation of histone acetylationFBgn0024291Sir2IMPFlyFB:FBrf0190776|PMID:16219773
Biological ProcessGO:0006355regulation of transcription, DNA-dependentRGD:1308542Sirt1_predictedISSRatRGD:1580654
Biological ProcessGO:0007584response to nutrientFBgn0024291Sir2IMPFlyFB:FBrf0154651
Biological ProcessGO:0031667response to nutrient levelsRGD:1308542Sirt1_predictedIEPRatRGD:1580412|PMID:15205477
Biological ProcessGO:0007283spermatogenesisMGI:2135607Sirt1IMPMouseMGI:MGI:2447945|PMID:12482959
Biological ProcessGO:0007283spermatogenesisRGD:1308542Sirt1_predictedISSRatRGD:1580654

Gene Ontology Evidence Code Abbreviations:

  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Not recorded (appears in some legacy annotations)