Compare GO annotations for HomoloGene:593 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0042166	acetylcholine binding	RGD:2348	Chrna7	IMP	Rat	RGD:1600971\|PMID:16186249
Molecular Function	GO:0042166	acetylcholine binding	FBgn0028875	nAcRalpha-34E	IDA	Fly	FB:FBrf0187807
Molecular Function	GO:0015464	acetylcholine receptor activity	RGD:2348	Chrna7	ISS	Rat	RGD:1580655
Molecular Function	GO:0008179	adenylate cyclase binding	RGD:2348	Chrna7	IPI	Rat	RGD:1600980\|PMID:12748066
Molecular Function	GO:0008144	drug binding	RGD:2348	Chrna7	IDA	Rat	RGD:1600992\|PMID:15801858
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:85056\|PMID:9037516
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	MGI:99779	Chrna7	ISS	Mouse	MGI:MGI:2154458
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:1099674\|PMID:9364063
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:2158987\|PMID:11834293
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	RGD:2348	Chrna7	IDA	Rat	RGD:727702\|PMID:12069582
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	RGD:2348	Chrna7	ISS	Rat	RGD:1580654
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	RGD:2348	Chrna7	ISS	Rat	RGD:1580655
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	RGD:2348	Chrna7	IDA	Rat	RGD:null
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	RGD:2348	Chrna7	IMP	Rat	RGD:null
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	RGD:2348	Chrna7	IMP	Rat	RGD:1600971\|PMID:16186249
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	FBgn0028875	nAcRalpha-34E	ISS	Fly	FB:FBrf0105495
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	FBgn0028875	nAcRalpha-34E	ISS	Fly	FB:FBrf0112152\|PMID:10471707
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	FBgn0028875	nAcRalpha-34E	ISS	Fly	FB:FBrf0127201\|PMID:10798390
Molecular Function	GO:0005515	protein binding	P36544	ACHA7_HUMAN	IPI	Human	PMID:10681545
Molecular Function	GO:0005515	protein binding	MGI:99779	Chrna7	IPI	Mouse	MGI:MGI:2176631\|PMID:11906696
Molecular Function	GO:0005515	protein binding	RGD:2348	Chrna7	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	RGD:2348	Chrna7	ISS	Rat	RGD:1580655
Molecular Function	GO:0005515	protein binding	RGD:2348	Chrna7	IPI	Rat	RGD:null
Cellular Component	GO:0016324	apical plasma membrane	MGI:99779	Chrna7	IDA	Mouse	MGI:MGI:3603731\|PMID:16033766
Cellular Component	GO:0032279	asymmetric synapse	RGD:2348	Chrna7	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0030424	axon	RGD:2348	Chrna7	IDA	Rat	RGD:704420\|PMID:12645078
Cellular Component	GO:0030424	axon	RGD:2348	Chrna7	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0043025	cell soma	RGD:2348	Chrna7	IDA	Rat	RGD:704420\|PMID:12645078
Cellular Component	GO:0005737	cytoplasm	RGD:2348	Chrna7	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0043198	dendritic shaft	RGD:2348	Chrna7	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0043197	dendritic spine	RGD:2348	Chrna7	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0009897	external side of plasma membrane	MGI:99779	Chrna7	IDA	Mouse	MGI:MGI:3610855\|PMID:15963492
Cellular Component	GO:0005615	extracellular space	RGD:2348	Chrna7	ISS	Rat	RGD:1580654
Cellular Component	GO:0030426	growth cone	RGD:2348	Chrna7	IDA	Rat	RGD:704420\|PMID:12645078
Cellular Component	GO:0016021	integral to membrane	RGD:2348	Chrna7	ISS	Rat	RGD:1580654
Cellular Component	GO:0045121	lipid raft	RGD:2348	Chrna7	IDA	Rat	RGD:1600980\|PMID:12748066
Cellular Component	GO:0005624	membrane fraction	MGI:99779	Chrna7	IDA	Mouse	MGI:MGI:2158987\|PMID:11834293
Cellular Component	GO:0005892	nicotinic acetylcholine-gated receptor-channel complex	RGD:2348	Chrna7	ISS	Rat	RGD:1580655
Cellular Component	GO:0005892	nicotinic acetylcholine-gated receptor-channel complex	RGD:2348	Chrna7	IDA	Rat	RGD:704420\|PMID:12645078
Cellular Component	GO:0005892	nicotinic acetylcholine-gated receptor-channel complex	FBgn0028875	nAcRalpha-34E	ISS	Fly	FB:FBrf0127201\|PMID:10798390
Cellular Component	GO:0005886	plasma membrane	P36544	ACHA7_HUMAN	IDA	Human	PMID:12508119
Cellular Component	GO:0005886	plasma membrane	MGI:99779	Chrna7	ISS	Mouse	MGI:MGI:2154458
Cellular Component	GO:0005886	plasma membrane	RGD:2348	Chrna7	IDA	Rat	RGD:1600980\|PMID:12748066
Cellular Component	GO:0014069	postsynaptic density	RGD:2348	Chrna7	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0042734	presynaptic membrane	RGD:2348	Chrna7	IDA	Rat	RGD:1600985\|PMID:12077196
Biological Process	GO:0000187	activation of MAPK activity	RGD:2348	Chrna7	ISS	Rat	RGD:1580655
Biological Process	GO:0008306	associative learning	MGI:99779	Chrna7	IGI	Mouse	MGI:MGI:3513661\|PMID:15541879
Biological Process	GO:0008306	associative learning	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3580035\|PMID:15922075
Biological Process	GO:0042113	B cell activation	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3610855\|PMID:15963492
Biological Process	GO:0042113	B cell activation	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3663537\|PMID:16253349
Biological Process	GO:0048149	behavioral response to ethanol	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3511640\|PMID:15489024
Biological Process	GO:0006816	calcium ion transport	MGI:99779	Chrna7	ISS	Mouse	MGI:MGI:2154458
Biological Process	GO:0006816	calcium ion transport	RGD:2348	Chrna7	IMP	Rat	RGD:null
Biological Process	GO:0042416	dopamine biosynthetic process	RGD:2348	Chrna7	IEP	Rat	RGD:704388\|PMID:12438507
Biological Process	GO:0019228	generation of action potential	RGD:2348	Chrna7	IMP	Rat	RGD:1600975\|PMID:15044058
Biological Process	GO:0060112	generation of menstrual cycle rhythm	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3053480\|PMID:15364017
Biological Process	GO:0006811	ion transport	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:1099674\|PMID:9364063
Biological Process	GO:0006811	ion transport	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:1355142\|PMID:10800961
Biological Process	GO:0042698	menstrual cycle	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3052645\|PMID:1400473
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3040787\|PMID:12508119
Biological Process	GO:0032715	negative regulation of interleukin-6 production	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3040787\|PMID:12508119
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	P36544	ACHA7_HUMAN	IDA	Human	PMID:12508119
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	MGI:99779	Chrna7	ISS	Mouse	MGI:MGI:2154458
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3040787\|PMID:12508119
Biological Process	GO:0001988	positive regulation of heart contraction rate in baroreceptor response to decreased blood pressure	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3531222\|PMID:10942027
Biological Process	GO:0050727	regulation of inflammatory response	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3040787\|PMID:12508119
Biological Process	GO:0042391	regulation of membrane potential	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:1099674\|PMID:9364063
Biological Process	GO:0042391	regulation of membrane potential	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:1355142\|PMID:10800961
Biological Process	GO:0042391	regulation of membrane potential	MGI:99779	Chrna7	ISS	Mouse	MGI:MGI:2154458
Biological Process	GO:0014061	regulation of norepinephrine secretion	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3531222\|PMID:10942027
Biological Process	GO:0045471	response to ethanol	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3612839\|PMID:15555774
Biological Process	GO:0032094	response to food	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3580035\|PMID:15922075
Biological Process	GO:0007165	signal transduction	RGD:2348	Chrna7	ISS	Rat	RGD:1580655
Biological Process	GO:0030317	sperm motility	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3691713\|PMID:15944242
Biological Process	GO:0007268	synaptic transmission	RGD:2348	Chrna7	ISS	Rat	RGD:1580655
Biological Process	GO:0007271	synaptic transmission, cholinergic	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:1099674\|PMID:9364063
Biological Process	GO:0007271	synaptic transmission, cholinergic	RGD:2348	Chrna7	IMP	Rat	RGD:1600975\|PMID:15044058
Biological Process	GO:0042110	T cell activation	MGI:99779	Chrna7	IMP	Mouse	MGI:MGI:3663537\|PMID:16253349

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)