Compare GO annotations for HomoloGene:623 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0008227	amine receptor activity	FBgn0053517	D2R	ISS	Fly	FB:FBrf0129744\|PMID:10908591
Molecular Function	GO:0035240	dopamine binding	RGD:2521	Drd3	IMP	Rat	RGD:1625068\|PMID:16490190
Molecular Function	GO:0001591	dopamine D2 receptor-like receptor activity	FBgn0053517	D2R	IDA	Fly	FB:FBrf0146094
Molecular Function	GO:0001591	dopamine D2 receptor-like receptor activity	ZDB-GENE-021119-1	drd3	ISS	Zfin	ZFIN:ZDB-PUB-040611-6\|PMID:15188433
Molecular Function	GO:0001592	dopamine D3 receptor activity	MGI:94925	Drd3	IDA	Mouse	MGI:MGI:71957\|PMID:8449953
Molecular Function	GO:0001592	dopamine D3 receptor activity	MGI:94925	Drd3	IDA	Mouse	MGI:MGI:79633\|PMID:8700864
Molecular Function	GO:0001592	dopamine D3 receptor activity	MGI:94925	Drd3	IDA	Mouse	MGI:MGI:81621\|PMID:8836575
Molecular Function	GO:0001592	dopamine D3 receptor activity	MGI:94925	Drd3	IDA	Mouse	MGI:MGI:76570\|PMID:7566118
Molecular Function	GO:0004952	dopamine receptor activity	RGD:2521	Drd3	ISS	Rat	RGD:1580654
Molecular Function	GO:0004952	dopamine receptor activity	RGD:2521	Drd3	IMP	Rat	RGD:1625068\|PMID:16490190
Molecular Function	GO:0004952	dopamine receptor activity	FBgn0053517	D2R	ISS	Fly	FB:FBrf0105495
Molecular Function	GO:0004952	dopamine receptor activity	FBgn0053517	D2R	IDA	Fly	FB:FBrf0152322\|PMID:12391323
Molecular Function	GO:0008144	drug binding	RGD:2521	Drd3	IDA	Rat	RGD:1625068\|PMID:16490190
Molecular Function	GO:0004930	G-protein coupled receptor activity	FBgn0053517	D2R	ISS	Fly	FB:FBrf0129744\|PMID:10908591
Molecular Function	GO:0005515	protein binding	MGI:94925	Drd3	IPI	Mouse	MGI:MGI:3618440\|PMID:16386234
Molecular Function	GO:0005515	protein binding	RGD:2521	Drd3	IPI	Rat	RGD:1581469\|PMID:16902178
Molecular Function	GO:0005515	protein binding	RGD:2521	Drd3	IPI	Rat	RGD:1302428\|PMID:14499480
Molecular Function	GO:0019904	protein domain specific binding	RGD:2521	Drd3	IPI	Rat	RGD:1581465\|PMID:14617818
Cellular Component	GO:0045177	apical part of cell	RGD:2521	Drd3	IDA	Rat	RGD:1625082\|PMID:9822449
Cellular Component	GO:0042995	cell projection	RGD:2521	Drd3	IDA	Rat	RGD:1581464\|PMID:15584906
Cellular Component	GO:0030139	endocytic vesicle	RGD:2521	Drd3	IDA	Rat	RGD:1581465\|PMID:14617818
Cellular Component	GO:0016021	integral to membrane	RGD:2521	Drd3	ISS	Rat	RGD:1580654
Cellular Component	GO:0016021	integral to membrane	FBgn0053517	D2R	ISS	Fly	FB:FBrf0105495
Cellular Component	GO:0016021	integral to membrane	FBgn0053517	D2R	ISS	Fly	FB:FBrf0129744\|PMID:10908591
Cellular Component	GO:0016021	integral to membrane	ZDB-GENE-021119-1	drd3	ISS	Zfin	ZFIN:ZDB-PUB-040611-6\|PMID:15188433
Cellular Component	GO:0005624	membrane fraction	MGI:94925	Drd3	IDA	Mouse	MGI:MGI:1270080\|PMID:9651217
Cellular Component	GO:0005886	plasma membrane	MGI:94925	Drd3	IDA	Mouse	MGI:MGI:1270080\|PMID:9651217
Cellular Component	GO:0005886	plasma membrane	MGI:94925	Drd3	IDA	Mouse	MGI:MGI:3618440\|PMID:16386234
Cellular Component	GO:0005886	plasma membrane	RGD:2521	Drd3	ISS	Rat	RGD:69828\|PMID:1953708
Cellular Component	GO:0005886	plasma membrane	RGD:2521	Drd3	IDA	Rat	RGD:1302428\|PMID:14499480
Biological Process	GO:0048148	behavioral response to cocaine	MGI:94925	Drd3	IGI	Mouse	MGI:MGI:3608235\|PMID:16197514
Biological Process	GO:0048148	behavioral response to cocaine	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3610635\|PMID:10943692
Biological Process	GO:0032922	circadian regulation of gene expression	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3611612\|PMID:15878801
Biological Process	GO:0007212	dopamine receptor signaling pathway	RGD:2521	Drd3	IMP	Rat	RGD:1625068\|PMID:16490190
Biological Process	GO:0007212	dopamine receptor signaling pathway	FBgn0053517	D2R	ISS	Fly	FB:FBrf0105495
Biological Process	GO:0007212	dopamine receptor signaling pathway	FBgn0053517	D2R	IDA	Fly	FB:FBrf0152322\|PMID:12391323
Biological Process	GO:0007212	dopamine receptor signaling pathway	ZDB-GENE-021119-1	drd3	ISS	Zfin	ZFIN:ZDB-PUB-040611-6\|PMID:15188433
Biological Process	GO:0007191	dopamine receptor, adenylate cyclase activating pathway	MGI:94925	Drd3	IDA	Mouse	MGI:MGI:3618440\|PMID:16386234
Biological Process	GO:0002031	G-protein coupled receptor internalization	RGD:2521	Drd3	IDA	Rat	RGD:1581465\|PMID:14617818
Biological Process	GO:0007186	G-protein coupled receptor protein signaling pathway	RGD:2521	Drd3	IMP	Rat	RGD:1625070\|PMID:15265811
Biological Process	GO:0007186	G-protein coupled receptor protein signaling pathway	FBgn0053517	D2R	ISS	Fly	FB:FBrf0129744\|PMID:10908591
Biological Process	GO:0007626	locomotory behavior	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3698022\|PMID:12044470
Biological Process	GO:0007626	locomotory behavior	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:79633\|PMID:8700864
Biological Process	GO:0007626	locomotory behavior	MGI:94925	Drd3	IGI	Mouse	MGI:MGI:1098940\|PMID:9354330
Biological Process	GO:0007626	locomotory behavior	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:1100811\|PMID:9402626
Biological Process	GO:0007626	locomotory behavior	MGI:94925	Drd3	IGI	Mouse	MGI:MGI:2450222\|PMID:12574430
Biological Process	GO:0007626	locomotory behavior	MGI:94925	Drd3	IGI	Mouse	MGI:MGI:3529730\|PMID:11864730
Biological Process	GO:0007626	locomotory behavior	MGI:94925	Drd3	IGI	Mouse	MGI:MGI:3610833\|PMID:12652349
Biological Process	GO:0007626	locomotory behavior	MGI:94925	Drd3	IGI	Mouse	MGI:MGI:3607822\|PMID:10884517
Biological Process	GO:0007626	locomotory behavior	MGI:94925	Drd3	IGI	Mouse	MGI:MGI:3608235\|PMID:16197514
Biological Process	GO:0050883	musculoskeletal movement, spinal reflex action	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3531598\|PMID:15601940
Biological Process	GO:0045776	negative regulation of blood pressure	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3690706\|PMID:9691085
Biological Process	GO:0060160	negative regulation of dopamine receptor signaling pathway	MGI:94925	Drd3	IGI	Mouse	MGI:MGI:3626135\|PMID:12097513
Biological Process	GO:0048715	negative regulation of oligodendrocyte differentiation	MGI:94925	Drd3	IDA	Mouse	MGI:MGI:1270080\|PMID:9651217
Biological Process	GO:0051898	negative regulation of protein kinase B signaling cascade	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3697576\|PMID:17251429
Biological Process	GO:0032416	negative regulation of sodium:hydrogen antiporter activity	RGD:2521	Drd3	IMP	Rat	RGD:1625070\|PMID:15265811
Biological Process	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	RGD:2521	Drd3	IDA	Rat	RGD:1581469\|PMID:16902178
Biological Process	GO:0008284	positive regulation of cell proliferation	RGD:2521	Drd3	IDA	Rat	RGD:1581464\|PMID:15584906
Biological Process	GO:0060161	positive regulation of dopamine receptor signaling pathway	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3621386\|PMID:15016423
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	RGD:2521	Drd3	IDA	Rat	RGD:1581469\|PMID:16902178
Biological Process	GO:0040014	regulation of body size	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3039963\|PMID:15084447
Biological Process	GO:0045187	regulation of circadian sleep/wake cycle, sleep	RGD:2521	Drd3	IMP	Rat	RGD:1625069\|PMID:15913875
Biological Process	GO:0014059	regulation of dopamine secretion	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3698022\|PMID:12044470
Biological Process	GO:0014059	regulation of dopamine secretion	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:1202050\|PMID:9482807
Biological Process	GO:0019216	regulation of lipid metabolic process	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3039963\|PMID:15084447
Biological Process	GO:0040012	regulation of locomotion	RGD:2521	Drd3	IMP	Rat	RGD:1625069\|PMID:15913875
Biological Process	GO:0002016	renin-angiotensin regulation of body fluid levels	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3690706\|PMID:9691085
Biological Process	GO:0002016	renin-angiotensin regulation of body fluid levels	MGI:94925	Drd3	IGI	Mouse	MGI:MGI:3690706\|PMID:9691085
Biological Process	GO:0001975	response to amphetamine	MGI:94925	Drd3	IGI	Mouse	MGI:MGI:3626135\|PMID:12097513
Biological Process	GO:0042220	response to cocaine	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3610635\|PMID:10943692
Biological Process	GO:0045471	response to ethanol	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3622567\|PMID:11988344
Biological Process	GO:0043278	response to morphine	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:2450222\|PMID:12574430
Biological Process	GO:0001963	synaptic transmission, dopaminergic	RGD:2521	Drd3	IMP	Rat	RGD:1625068\|PMID:16490190
Biological Process	GO:0008542	visual learning	MGI:94925	Drd3	IMP	Mouse	MGI:MGI:3626135\|PMID:12097513

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)