Compare GO annotations for HomoloGene:6507 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0005524	ATP binding	P49770	EI2BB_HUMAN	IDA	Human	PMID:11323413
Molecular Function	GO:0005524	ATP binding	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Molecular Function	GO:0030234	enzyme regulator activity	S000004282	GCD7	IMP	Yeast	SGD_REF:S000049564\|PMID:9032257
Molecular Function	GO:0030234	enzyme regulator activity	S000004282	GCD7	IPI	Yeast	SGD_REF:S000043342\|PMID:8887689
Molecular Function	GO:0030234	enzyme regulator activity	S000004282	GCD7	IGI	Yeast	SGD_REF:S000043342\|PMID:8887689
Molecular Function	GO:0030234	enzyme regulator activity	S000004282	GCD7	IGI	Yeast	SGD_REF:S000045038\|PMID:8164676
Molecular Function	GO:0005525	GTP binding	P49770	EI2BB_HUMAN	IDA	Human	PMID:11323413
Molecular Function	GO:0005525	GTP binding	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	P49770	EI2BB_HUMAN	IMP	Human	PMID:15054402
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	P49770	EI2BB_HUMAN	IDA	Human	PMID:11323413
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	MGI:2145118	Eif2b2	ISS	Mouse	MGI:MGI:2154458
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RGD:620820	Eif2b2	ISS	Rat	RGD:1580655
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	S000004282	GCD7	IPI	Yeast	SGD_REF:S000049992\|PMID:8336705
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	S000004282	GCD7	IDA	Yeast	SGD_REF:S000048815\|PMID:8506384
Molecular Function	GO:0005515	protein binding	P49770	EI2BB_HUMAN	IPI	Human	PMID:15060152
Molecular Function	GO:0005515	protein binding	MGI:2145118	Eif2b2	ISS	Mouse	MGI:MGI:2154458
Molecular Function	GO:0005515	protein binding	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Molecular Function	GO:0003743	translation initiation factor activity	P49770	EI2BB_HUMAN	IDA	Human	PMID:16289705
Molecular Function	GO:0003743	translation initiation factor activity	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Molecular Function	GO:0003743	translation initiation factor activity	FBgn0024996	eIF2B-beta	ISS	Fly	FB:FBrf0071734
Molecular Function	GO:0003743	translation initiation factor activity	FBgn0024996	eIF2B-beta	ISS	Fly	FB:FBrf0129923\|PMID:10908586
Molecular Function	GO:0003743	translation initiation factor activity	FBgn0024996	eIF2B-beta	ISS	Fly	FB:FBrf0132369\|PMID:11060303
Molecular Function	GO:0003743	translation initiation factor activity	S000004282	GCD7	IPI	Yeast	SGD_REF:S000049992\|PMID:8336705
Molecular Function	GO:0003743	translation initiation factor activity	S000004282	GCD7	IGI	Yeast	SGD_REF:S000049992\|PMID:8336705
Molecular Function	GO:0003743	translation initiation factor activity	SPAC343.14c	SPAC343.14c	ISS	Pombe	GOC:unpublished
Cellular Component	GO:0005737	cytoplasm	P49770	EI2BB_HUMAN	IDA	Human	PMID:11323413
Cellular Component	GO:0005737	cytoplasm	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Cellular Component	GO:0005829	cytosol	FBgn0024996	eIF2B-beta	ISS	Fly	FB:FBrf0071734
Cellular Component	GO:0005829	cytosol	FBgn0024996	eIF2B-beta	ISS	Fly	FB:FBrf0129923\|PMID:10908586
Cellular Component	GO:0005829	cytosol	SPAC343.14c	SPAC343.14c	IDA	Pombe	PMID:16823372
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	P49770	EI2BB_HUMAN	IDA	Human	PMID:11323413
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	P49770	EI2BB_HUMAN	IDA	Human	PMID:15060152
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	MGI:2145118	Eif2b2	ISS	Mouse	MGI:MGI:2154458
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	RGD:620820	Eif2b2	ISS	Rat	RGD:1580655
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	FBgn0024996	eIF2B-beta	ISS	Fly	FB:FBrf0071734
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	FBgn0024996	eIF2B-beta	ISS	Fly	FB:FBrf0129923\|PMID:10908586
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	FBgn0024996	eIF2B-beta	ISS	Fly	FB:FBrf0132369\|PMID:11060303
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000004282	GCD7	IMP	Yeast	SGD_REF:S000048683\|PMID:8441423
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000004282	GCD7	IPI	Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000004282	GCD7	IDA	Yeast	SGD_REF:S000048815\|PMID:8506384
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000004282	GCD7	IDA	Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000004282	GCD7	IGI	Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	S000004282	GCD7	IPI	Yeast	SGD_REF:S000048815\|PMID:8506384
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	SPAC343.14c	SPAC343.14c	ISS	Pombe	GOC:unpublished
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	S000004282	GCD7	IPI	Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	S000004282	GCD7	IDA	Yeast	SGD_REF:S000048815\|PMID:8506384
Cellular Component	GO:0005739	mitochondrion	S000004282	GCD7	IDA	Yeast	SGD_REF:S000075100\|PMID:14576278
Cellular Component	GO:0005739	mitochondrion	S000004282	GCD7	IDA	Yeast	SGD_REF:S000117178\|PMID:16823961
Cellular Component	GO:0005634	nucleus	SPAC343.14c	SPAC343.14c	IDA	Pombe	PMID:16823372
Biological Process	GO:0051716	cellular response to stimulus	P49770	EI2BB_HUMAN	IDA	Human	PMID:8626696
Biological Process	GO:0051716	cellular response to stimulus	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Biological Process	GO:0007417	central nervous system development	P49770	EI2BB_HUMAN	IMP	Human	PMID:15776425
Biological Process	GO:0007417	central nervous system development	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Biological Process	GO:0042552	myelination	P49770	EI2BB_HUMAN	IMP	Human	PMID:14566705
Biological Process	GO:0042552	myelination	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Biological Process	GO:0014003	oligodendrocyte development	P49770	EI2BB_HUMAN	IMP	Human	PMID:15217090
Biological Process	GO:0014003	oligodendrocyte development	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Biological Process	GO:0001541	ovarian follicle development	P49770	EI2BB_HUMAN	IMP	Human	PMID:15507143
Biological Process	GO:0001541	ovarian follicle development	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Biological Process	GO:0006446	regulation of translational initiation	S000004282	GCD7	IDA	Yeast	SGD_REF:S000048815\|PMID:8506384
Biological Process	GO:0006446	regulation of translational initiation	S000004282	GCD7	IGI	Yeast	SGD_REF:S000045038\|PMID:8164676
Biological Process	GO:0006446	regulation of translational initiation	S000004282	GCD7	IGI	Yeast	SGD_REF:S000043342\|PMID:8887689
Biological Process	GO:0006446	regulation of translational initiation	S000004282	GCD7	IPI	Yeast	SGD_REF:S000043342\|PMID:8887689
Biological Process	GO:0006446	regulation of translational initiation	S000004282	GCD7	IMP	Yeast	SGD_REF:S000049564\|PMID:9032257
Biological Process	GO:0009749	response to glucose stimulus	P49770	EI2BB_HUMAN	ISS	Human	UniProt:P49770
Biological Process	GO:0009749	response to glucose stimulus	RGD:620820	Eif2b2	IDA	Rat	RGD:null
Biological Process	GO:0009408	response to heat	P49770	EI2BB_HUMAN	ISS	Human	UniProt:P49770
Biological Process	GO:0009408	response to heat	RGD:620820	Eif2b2	IDA	Rat	RGD:null
Biological Process	GO:0043434	response to peptide hormone stimulus	P49770	EI2BB_HUMAN	ISS	Human	UniProt:P49770
Biological Process	GO:0043434	response to peptide hormone stimulus	RGD:620820	Eif2b2	IDA	Rat	RGD:null
Biological Process	GO:0006413	translational initiation	RGD:620820	Eif2b2	ISS	Rat	RGD:1580655
Biological Process	GO:0006413	translational initiation	RGD:620820	Eif2b2	ISS	Rat	RGD:1600115
Biological Process	GO:0006413	translational initiation	FBgn0024996	eIF2B-beta	ISS	Fly	FB:FBrf0071734
Biological Process	GO:0006413	translational initiation	FBgn0024996	eIF2B-beta	ISS	Fly	FB:FBrf0129923\|PMID:10908586
Biological Process	GO:0006413	translational initiation	FBgn0024996	eIF2B-beta	ISS	Fly	FB:FBrf0132369\|PMID:11060303
Biological Process	GO:0006413	translational initiation	SPAC343.14c	SPAC343.14c	ISS	Pombe	GOC:unpublished

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)