Compare GO annotations for HomoloGene:676 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	RGD:2871	Igf2r	IDA	Rat	RGD:1581738\|PMID:11247783
Molecular Function	GO:0001965	G-protein alpha-subunit binding	RGD:2871	Igf2r	IDA	Rat	RGD:1624326\|PMID:16407557
Molecular Function	GO:0005520	insulin-like growth factor binding	MGI:96435	Igf2r	IPI	Mouse	MGI:MGI:2679358\|PMID:14566968
Molecular Function	GO:0005520	insulin-like growth factor binding	RGD:2871	Igf2r	ISS	Rat	RGD:1580654
Molecular Function	GO:0031995	insulin-like growth factor II binding	RGD:2871	Igf2r	IDA	Rat	RGD:1624326\|PMID:16407557
Molecular Function	GO:0005010	insulin-like growth factor receptor activity	RGD:2871	Igf2r	ISS	Rat	RGD:1580655
Molecular Function	GO:0005515	protein binding	FBgn0051072	Lerp	IPI	Fly	FB:FBrf0184046\|PMID:15664992
Molecular Function	GO:0004872	receptor activity	RGD:2871	Igf2r	ISS	Rat	RGD:1580655
Molecular Function	GO:0004872	receptor activity	FBgn0051072	Lerp	ISS	Fly	FB:FBrf0148886
Cellular Component	GO:0005768	endosome	P11717	MPRI_HUMAN	IDA	Human	PMID:15078902
Cellular Component	GO:0005768	endosome	MGI:96435	Igf2r	ISS	Mouse	MGI:MGI:3040541\|PMID:15078902
Cellular Component	GO:0005768	endosome	RGD:2871	Igf2r	ISS	Rat	RGD:1580655
Cellular Component	GO:0005615	extracellular space	RGD:2871	Igf2r	ISS	Rat	RGD:1580654
Cellular Component	GO:0016021	integral to membrane	RGD:2871	Igf2r	ISS	Rat	RGD:1580654
Cellular Component	GO:0005887	integral to plasma membrane	RGD:2871	Igf2r	ISS	Rat	RGD:1580655
Cellular Component	GO:0005624	membrane fraction	RGD:2871	Igf2r	IDA	Rat	RGD:1624326\|PMID:16407557
Cellular Component	GO:0005641	nuclear envelope lumen	MGI:96435	Igf2r	IDA	Mouse	MGI:MGI:2667274\|PMID:12729502
Cellular Component	GO:0005641	nuclear envelope lumen	RGD:2871	Igf2r	ISS	Rat	RGD:1580654
Cellular Component	GO:0005634	nucleus	MGI:96435	Igf2r	IDA	Mouse	MGI:MGI:2667274\|PMID:12729502
Cellular Component	GO:0005634	nucleus	RGD:2871	Igf2r	ISS	Rat	RGD:1580654
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	P11717	MPRI_HUMAN	IDA	Human	PMID:15078902
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	MGI:96435	Igf2r	ISS	Mouse	MGI:MGI:3040541\|PMID:15078902
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	RGD:2871	Igf2r	ISS	Rat	RGD:1580655
Biological Process	GO:0007041	lysosomal transport	FBgn0051072	Lerp	IDA	Fly	FB:FBrf0184046\|PMID:15664992
Biological Process	GO:0006892	post-Golgi vesicle-mediated transport	FBgn0051072	Lerp	IDA	Fly	FB:FBrf0184046\|PMID:15664992
Biological Process	GO:0006898	receptor-mediated endocytosis	RGD:2871	Igf2r	ISS	Rat	RGD:1580655
Biological Process	GO:0042981	regulation of apoptosis	RGD:2871	Igf2r	IMP	Rat	RGD:1624325\|PMID:16825605
Biological Process	GO:0007165	signal transduction	RGD:2871	Igf2r	ISS	Rat	RGD:1580655

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)