Compare GO annotations for HomoloGene:68389 orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, fly, worm, tair, rice, yeast, pombe, pfalc, zfin.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Fly from Flybase; Worm from Wormbase; Tair from TAIR; Rice from Gramene; Yeast from SGD; Pombe from S.pombe Genome Project; Pfalc from PlasmoDB; Zfin from Zfin.
Organisms with experimental annotations are indicated: IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IC, IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Sep 18 15:47:31 2007.

Category	ID	Term	DB Object	DB Symbol	Evidence	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	MGI:99829	Runx2	IDA	Mouse	MGI:MGI:3513625\|PMID:15537544
Molecular Function	GO:0003682	chromatin binding	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Molecular Function	GO:0003677	DNA binding	MGI:99829	Runx2	IDA	Mouse	MGI:MGI:2673083\|PMID:12807883
Molecular Function	GO:0003677	DNA binding	MGI:99829	Runx2	IDA	Mouse	MGI:MGI:3039923\|PMID:15107406
Molecular Function	GO:0003677	DNA binding	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	Q13950	RUNX2_HUMAN	IPI	Human	PMID:12145306
Molecular Function	GO:0005515	protein binding	Q13950	RUNX2_HUMAN	IPI	Human	PMID:11965546
Molecular Function	GO:0005515	protein binding	MGI:99829	Runx2	IPI	Mouse	MGI:MGI:3694183\|PMID:16299379
Molecular Function	GO:0005515	protein binding	MGI:99829	Runx2	IPI	Mouse	MGI:MGI:3513625\|PMID:15537544
Molecular Function	GO:0005515	protein binding	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Molecular Function	GO:0005515	protein binding	RGD:2282	Runx2	ISS	Rat	RGD:1580655
Molecular Function	GO:0003702	RNA polymerase II transcription factor activity	RGD:2282	Runx2	ISS	Rat	RGD:1580655
Molecular Function	GO:0016563	transcription activator activity	Q13950	RUNX2_HUMAN	IDA	Human	PMID:11965546
Molecular Function	GO:0016563	transcription activator activity	RGD:2282	Runx2	ISS	Rat	RGD:1580655
Molecular Function	GO:0016563	transcription activator activity	RGD:2282	Runx2	IDA	Rat	RGD:1601650
Molecular Function	GO:0003700	transcription factor activity	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Molecular Function	GO:0003700	transcription factor activity	RGD:2282	Runx2	ISS	Rat	RGD:1580655
Molecular Function	GO:0003700	transcription factor activity	RGD:2282	Runx2	IDA	Rat	RGD:1601650
Molecular Function	GO:0003700	transcription factor activity	FBgn0031121	CG15455	ISS	Fly	FB:FBrf0105495
Molecular Function	GO:0003700	transcription factor activity	ZDB-GENE-040629-3	runx2a	ISS	Zfin	ZFIN:ZDB-PUB-040721-6\|PMID:15261836
Cellular Component	GO:0005737	cytoplasm	MGI:99829	Runx2	IDA	Mouse	MGI:MGI:3051083\|PMID:15225881
Cellular Component	GO:0005737	cytoplasm	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Cellular Component	GO:0005634	nucleus	MGI:99829	Runx2	IDA	Mouse	MGI:MGI:2446761\|PMID:12434156
Cellular Component	GO:0005634	nucleus	MGI:99829	Runx2	IDA	Mouse	MGI:MGI:3528208\|PMID:15565649
Cellular Component	GO:0005634	nucleus	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Cellular Component	GO:0005634	nucleus	RGD:2282	Runx2	IDA	Rat	RGD:1601650
Biological Process	GO:0048469	cell maturation	MGI:99829	Runx2	IGI	Mouse	MGI:MGI:3039923\|PMID:15107406
Biological Process	GO:0048469	cell maturation	MGI:99829	Runx2	IMP	Mouse	MGI:MGI:3528197\|PMID:15389629
Biological Process	GO:0048469	cell maturation	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Biological Process	GO:0009987	cellular process	FBgn0031121	CG15455	IMP	Fly	FB:FBrf0175143\|PMID:14764878
Biological Process	GO:0002062	chondrocyte differentiation	MGI:99829	Runx2	IGI	Mouse	MGI:MGI:3620436\|PMID:16476422
Biological Process	GO:0002062	chondrocyte differentiation	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	WBGene00004393	rnt-1	IMP	Worm	WB:WBPaper00026868\|PMID:16236764
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	MGI:99829	Runx2	IMP	Mouse	MGI:MGI:3656469\|PMID:15668330
Biological Process	GO:0016481	negative regulation of transcription	Q13950	RUNX2_HUMAN	IDA	Human	PMID:11965546
Biological Process	GO:0016481	negative regulation of transcription	RGD:2282	Runx2	ISS	Rat	RGD:1580655
Biological Process	GO:0042475	odontogenesis (sensu Vertebrata)	MGI:99829	Runx2	IMP	Mouse	MGI:MGI:3051915\|PMID:15136142
Biological Process	GO:0042475	odontogenesis (sensu Vertebrata)	MGI:99829	Runx2	IMP	Mouse	MGI:MGI:3656469\|PMID:15668330
Biological Process	GO:0042475	odontogenesis (sensu Vertebrata)	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Biological Process	GO:0001649	osteoblast differentiation	MGI:99829	Runx2	IGI	Mouse	MGI:MGI:3528208\|PMID:15565649
Biological Process	GO:0001649	osteoblast differentiation	MGI:99829	Runx2	IMP	Mouse	MGI:MGI:3528197\|PMID:15389629
Biological Process	GO:0001649	osteoblast differentiation	MGI:99829	Runx2	IGI	Mouse	MGI:MGI:3587162\|PMID:16099986
Biological Process	GO:0001649	osteoblast differentiation	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Biological Process	GO:0001649	osteoblast differentiation	RGD:2282	Runx2	ISS	Rat	RGD:1580655
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:99829	Runx2	IGI	Mouse	MGI:MGI:3620436\|PMID:16476422
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:99829	Runx2	IMP	Mouse	MGI:MGI:3656469\|PMID:15668330
Biological Process	GO:0008284	positive regulation of cell proliferation	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Biological Process	GO:0045778	positive regulation of ossification	RGD:2282	Runx2	IMP	Rat	RGD:1601657\|PMID:11784711
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:99829	Runx2	IDA	Mouse	MGI:MGI:2446761\|PMID:12434156
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:99829	Runx2	IDA	Mouse	MGI:MGI:3039923\|PMID:15107406
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:99829	Runx2	IGI	Mouse	MGI:MGI:3513625\|PMID:15537544
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:99829	Runx2	IGI	Mouse	MGI:MGI:3587162\|PMID:16099986
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Biological Process	GO:0045893	positive regulation of transcription, DNA-dependent	RGD:2282	Runx2	IDA	Rat	RGD:1601650
Biological Process	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	MGI:99829	Runx2	IMP	Mouse	MGI:MGI:3051915\|PMID:15136142
Biological Process	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Biological Process	GO:0042487	regulation of odontogenesis (sensu Vertebrata)	MGI:99829	Runx2	IMP	Mouse	MGI:MGI:2683810\|PMID:14688224
Biological Process	GO:0042487	regulation of odontogenesis (sensu Vertebrata)	RGD:2282	Runx2	ISS	Rat	RGD:1580654
Biological Process	GO:0006355	regulation of transcription, DNA-dependent	FBgn0031121	CG15455	ISS	Fly	FB:FBrf0105495
Biological Process	GO:0001501	skeletal development	MGI:99829	Runx2	IMP	Mouse	MGI:MGI:2683810\|PMID:14688224
Biological Process	GO:0001501	skeletal development	MGI:99829	Runx2	IMP	Mouse	MGI:MGI:3628871\|PMID:15050892
Biological Process	GO:0001501	skeletal development	RGD:2282	Runx2	ISS	Rat	RGD:1580654

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)