MGI MouseCyc GO annotations for PWY-2161

MGI MouseCyc GO annotations for PWY-2161: folate polyglutamylation I

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY-2161.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Fpgs	Mthfd1	Mthfd1l	Shmt1	Shmt2
Molecular Function	GO:0005488	binding	Fpgs	Mthfd1	Mthfd1l	Shmt1	Shmt2
Molecular Function	GO:0003824	catalytic activity	Fpgs	Mthfd1	Mthfd1l	Shmt1	Shmt2
Cellular Component	GO:0005623	cell	Fpgs	Mthfd1	Mthfd1l	Shmt1	Shmt2
Cellular Component	GO:0044464	cell part	Fpgs	Mthfd1	Mthfd1l	Shmt1	Shmt2
Cellular Component	GO:0031975	envelope	Fpgs	Mthfd1	Mthfd1l	Shmt1	Shmt2
Cellular Component	GO:0043226	organelle	Fpgs	Mthfd1	Mthfd1l	Shmt1	Shmt2
Cellular Component	GO:0044422	organelle part	Fpgs	Mthfd1	Mthfd1l	Shmt1	Shmt2
Biological Process	GO:0009987	cellular process	Fpgs	Mthfd1	Mthfd1l	Shmt1	Shmt2
Biological Process	GO:0008152	metabolic process	Fpgs	Mthfd1	Mthfd1l	Shmt1	Shmt2

Full set of annotations for PWY-2161

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0005524	ATP binding	Mthfd1	IEA	color key
Molecular Function	GO:0005524	ATP binding	Mthfd1l	IEA	color key
Molecular Function	GO:0005524	ATP binding	Fpgs	IEA	color key
Molecular Function	GO:0005488	binding	Mthfd1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Mthfd1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Shmt1	IEA	color key
Molecular Function	GO:0004329	formate-tetrahydrofolate ligase activity	Mthfd1	IEA	color key
Molecular Function	GO:0004329	formate-tetrahydrofolate ligase activity	Mthfd1l	ISO	color key
Molecular Function	GO:0016155	formyltetrahydrofolate dehydrogenase activity	Mthfd1	IMP	color key
Molecular Function	GO:0004372	glycine hydroxymethyltransferase activity	Shmt2	IEA	color key
Molecular Function	GO:0004372	glycine hydroxymethyltransferase activity	Shmt1	IEA	color key
Molecular Function	GO:0016787	hydrolase activity	Mthfd1	IEA	color key
Molecular Function	GO:0016874	ligase activity	Mthfd1	IEA	color key
Molecular Function	GO:0016874	ligase activity	Mthfd1l	IEA	color key
Molecular Function	GO:0016874	ligase activity	Fpgs	IEA	color key
Molecular Function	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity	Mthfd1	IEA	color key
Molecular Function	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Mthfd1	IEA	color key
Molecular Function	GO:0008168	methyltransferase activity	Shmt2	IEA	color key
Molecular Function	GO:0008168	methyltransferase activity	Shmt1	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Mthfd1	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Mthfd1l	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Fpgs	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Mthfd1	IEA	color key
Molecular Function	GO:0030170	pyridoxal phosphate binding	Shmt1	IEA	color key
Molecular Function	GO:0004326	tetrahydrofolylpolyglutamate synthase activity	Fpgs	IEA	color key
Molecular Function	GO:0016740	transferase activity	Shmt2	IEA	color key
Molecular Function	GO:0016740	transferase activity	Shmt1	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Mthfd1	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Fpgs	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Shmt1	IEA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Shmt2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Shmt2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Mthfd1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Mthfd1l	ISO	color key
Cellular Component	GO:0005739	mitochondrion	Fpgs	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Shmt1	IDA	color key
Biological Process	GO:0009257	10-formyltetrahydrofolate biosynthetic process	Mthfd1l	ISO	color key
Biological Process	GO:0008652	amino acid biosynthetic process	Mthfd1	IEA	color key
Biological Process	GO:0009058	biosynthetic process	Fpgs	IEA	color key
Biological Process	GO:0009396	folic acid and derivative biosynthetic process	Mthfd1	IEA	color key
Biological Process	GO:0009396	folic acid and derivative biosynthetic process	Fpgs	IEA	color key
Biological Process	GO:0006544	glycine metabolic process	Shmt1	IEA	color key
Biological Process	GO:0000105	histidine biosynthetic process	Mthfd1	IEA	color key
Biological Process	GO:0006548	histidine catabolic process	Mthfd1	IMP	color key
Biological Process	GO:0006563	L-serine metabolic process	Shmt1	IEA	color key
Biological Process	GO:0008152	metabolic process	Mthfd1	IEA	color key
Biological Process	GO:0009086	methionine biosynthetic process	Mthfd1	IEA	color key
Biological Process	GO:0006730	one-carbon compound metabolic process	Mthfd1	IEA	color key
Biological Process	GO:0006730	one-carbon compound metabolic process	Mthfd1l	IEA	color key
Biological Process	GO:0006730	one-carbon compound metabolic process	Fpgs	IEA	color key
Biological Process	GO:0006730	one-carbon compound metabolic process	Shmt1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Mthfd1	IEA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Mthfd1	IEA	color key