MGI MouseCyc GO annotations for PWY-3841

MGI MouseCyc GO annotations for PWY-3841: formylTHF biosynthesis II

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY-3841.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
Molecular Function	GO:0005488	binding	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
Molecular Function	GO:0003824	catalytic activity	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
Cellular Component	GO:0005623	cell	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
Cellular Component	GO:0044464	cell part	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
Cellular Component	GO:0031975	envelope	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
Cellular Component	GO:0043226	organelle	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
Cellular Component	GO:0044422	organelle part	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
Biological Process	GO:0009987	cellular process	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms
Biological Process	GO:0008152	metabolic process	Dhfr	Fpgs	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2	Tyms

Full set of annotations for PWY-3841

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity	Mthfs	IEA	color key
Molecular Function	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity	Mthfsd	IEA	color key
Molecular Function	GO:0005524	ATP binding	Mthfs	IEA	color key
Molecular Function	GO:0005524	ATP binding	Mthfd1	IEA	color key
Molecular Function	GO:0005524	ATP binding	Mthfd1l	IEA	color key
Molecular Function	GO:0005524	ATP binding	Mthfsd	IEA	color key
Molecular Function	GO:0005524	ATP binding	Fpgs	IEA	color key
Molecular Function	GO:0005488	binding	Mthfd1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Mthfr	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Mthfd2	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Gldc	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Mthfd1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Shmt1	IEA	color key
Molecular Function	GO:0031419	cobalamin binding	Mtr	IEA	color key
Molecular Function	GO:0050897	cobalt ion binding	Mtr	IEA	color key
Molecular Function	GO:0004146	dihydrofolate reductase activity	Dhfr	IDA	color key
Molecular Function	GO:0004156	dihydropteroate synthase activity	Mtr	IEA	color key
Molecular Function	GO:0005542	folic acid binding	Mthfs	IEA	color key
Molecular Function	GO:0004329	formate-tetrahydrofolate ligase activity	Mthfd1	IEA	color key
Molecular Function	GO:0004329	formate-tetrahydrofolate ligase activity	Mthfd1l	ISO	color key
Molecular Function	GO:0016155	formyltetrahydrofolate dehydrogenase activity	Mthfd1	IMP	color key
Molecular Function	GO:0004375	glycine dehydrogenase (decarboxylating) activity	Gldc	ISO	color key
Molecular Function	GO:0004372	glycine hydroxymethyltransferase activity	Shmt2	IEA	color key
Molecular Function	GO:0004372	glycine hydroxymethyltransferase activity	Shmt1	IEA	color key
Molecular Function	GO:0008898	homocysteine S-methyltransferase activity	Mtr	IEA	color key
Molecular Function	GO:0016787	hydrolase activity	Mthfd2	IEA	color key
Molecular Function	GO:0016787	hydrolase activity	Mthfd1	IEA	color key
Molecular Function	GO:0016874	ligase activity	Mthfs	IEA	color key
Molecular Function	GO:0016874	ligase activity	Mthfd1	IEA	color key
Molecular Function	GO:0016874	ligase activity	Mthfd1l	IEA	color key
Molecular Function	GO:0016874	ligase activity	Fpgs	IEA	color key
Molecular Function	GO:0000287	magnesium ion binding	Mthfd2	IEA	color key
Molecular Function	GO:0000287	magnesium ion binding	Mthfs	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Mtr	IEA	color key
Molecular Function	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity	Mthfd2	IEA	color key
Molecular Function	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity	Mthfd1	IEA	color key
Molecular Function	GO:0008705	methionine synthase activity	Mtr	IMP	color key
Molecular Function	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity	Mthfd2	IEA	color key
Molecular Function	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Mthfd2	IEA	color key
Molecular Function	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Mthfd1	IEA	color key
Molecular Function	GO:0004489	methylenetetrahydrofolate reductase (NADPH) activity	Mthfr	IMP	color key
Molecular Function	GO:0008168	methyltransferase activity	Shmt2	IEA	color key
Molecular Function	GO:0008168	methyltransferase activity	Mtr	IEA	color key
Molecular Function	GO:0008168	methyltransferase activity	Shmt1	IEA	color key
Molecular Function	GO:0008168	methyltransferase activity	Tyms	IEA	color key
Molecular Function	GO:0003676	nucleic acid binding	Mthfsd	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Mthfd1	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Mthfd1l	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Mthfsd	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Fpgs	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Mthfr	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Mthfd2	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Gldc	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Mthfd1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Dhfr	IEA	color key
Molecular Function	GO:0042803	protein homodimerization activity	Gldc	ISO	color key
Molecular Function	GO:0030170	pyridoxal phosphate binding	Gldc	IEA	color key
Molecular Function	GO:0030170	pyridoxal phosphate binding	Shmt1	IEA	color key
Molecular Function	GO:0003723	RNA binding	Mthfsd	IEA	color key
Molecular Function	GO:0004326	tetrahydrofolylpolyglutamate synthase activity	Fpgs	IEA	color key
Molecular Function	GO:0004799	thymidylate synthase activity	Tyms	IEA	color key
Molecular Function	GO:0016740	transferase activity	Shmt2	IEA	color key
Molecular Function	GO:0016740	transferase activity	Mtr	IEA	color key
Molecular Function	GO:0016740	transferase activity	Shmt1	IEA	color key
Molecular Function	GO:0016740	transferase activity	Tyms	IEA	color key
Molecular Function	GO:0008270	zinc ion binding	Mtr	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Mthfs	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Mthfd1	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Mtr	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Fpgs	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Shmt1	IEA	color key
Cellular Component	GO:0005622	intracellular	Mtr	IEA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Shmt2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Shmt2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Mthfd2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Gldc	ISO	color key
Cellular Component	GO:0005739	mitochondrion	Mthfd1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Mthfd1l	ISO	color key
Cellular Component	GO:0005739	mitochondrion	Fpgs	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Shmt1	IDA	color key
Biological Process	GO:0009257	10-formyltetrahydrofolate biosynthetic process	Mthfd1l	ISO	color key
Biological Process	GO:0008652	amino acid biosynthetic process	Mthfd1	IEA	color key
Biological Process	GO:0008652	amino acid biosynthetic process	Mtr	IEA	color key
Biological Process	GO:0009058	biosynthetic process	Fpgs	IEA	color key
Biological Process	GO:0006231	dTMP biosynthetic process	Tyms	IEA	color key
Biological Process	GO:0009396	folic acid and derivative biosynthetic process	Mthfd2	IEA	color key
Biological Process	GO:0009396	folic acid and derivative biosynthetic process	Mthfs	IEA	color key
Biological Process	GO:0009396	folic acid and derivative biosynthetic process	Mthfd1	IEA	color key
Biological Process	GO:0009396	folic acid and derivative biosynthetic process	Mthfsd	IEA	color key
Biological Process	GO:0009396	folic acid and derivative biosynthetic process	Mtr	IEA	color key
Biological Process	GO:0009396	folic acid and derivative biosynthetic process	Fpgs	IEA	color key
Biological Process	GO:0006545	glycine biosynthetic process	Dhfr	IEA	color key
Biological Process	GO:0019464	glycine decarboxylation via glycine cleavage system	Gldc	ISO	color key
Biological Process	GO:0006544	glycine metabolic process	Gldc	IEA	color key
Biological Process	GO:0006544	glycine metabolic process	Shmt1	IEA	color key
Biological Process	GO:0000105	histidine biosynthetic process	Mthfd1	IEA	color key
Biological Process	GO:0006548	histidine catabolic process	Mthfd1	IMP	color key
Biological Process	GO:0006563	L-serine metabolic process	Shmt1	IEA	color key
Biological Process	GO:0008152	metabolic process	Mthfd1	IEA	color key
Biological Process	GO:0009086	methionine biosynthetic process	Mthfr	IMP	color key
Biological Process	GO:0009086	methionine biosynthetic process	Mthfd1	IEA	color key
Biological Process	GO:0009086	methionine biosynthetic process	Mtr	IMP	color key
Biological Process	GO:0006555	methionine metabolic process	Mthfr	IEA	color key
Biological Process	GO:0009165	nucleotide biosynthetic process	Dhfr	IEA	color key
Biological Process	GO:0009165	nucleotide biosynthetic process	Tyms	IEA	color key
Biological Process	GO:0006730	one-carbon compound metabolic process	Mthfd2	IEA	color key
Biological Process	GO:0006730	one-carbon compound metabolic process	Mthfd1	IEA	color key
Biological Process	GO:0006730	one-carbon compound metabolic process	Mthfd1l	IEA	color key
Biological Process	GO:0006730	one-carbon compound metabolic process	Dhfr	IEA	color key
Biological Process	GO:0006730	one-carbon compound metabolic process	Fpgs	IEA	color key
Biological Process	GO:0006730	one-carbon compound metabolic process	Shmt1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Mthfr	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Mthfd2	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Gldc	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Mthfd1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Dhfr	IEA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Mthfd1	IEA	color key