MGI MouseCyc GO annotations for PWY-4041

MGI MouseCyc GO annotations for PWY-4041: γ-glutamyl cycle

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY-4041.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Molecular Function	GO:0005488	binding	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Molecular Function	GO:0003824	catalytic activity	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Cellular Component	GO:0005623	cell	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Cellular Component	GO:0044464	cell part	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Cellular Component	GO:0032991	macromolecular complex	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Biological Process	GO:0065007	biological regulation	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Biological Process	GO:0009987	cellular process	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Biological Process	GO:0032502	developmental process	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Biological Process	GO:0008152	metabolic process	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Biological Process	GO:0032501	multicellular organismal process	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Biological Process	GO:0048519	negative regulation of biological process	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Biological Process	GO:0048518	positive regulation of biological process	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Biological Process	GO:0050789	regulation of biological process	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Biological Process	GO:0000003	reproduction	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Biological Process	GO:0022414	reproductive process	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah
Biological Process	GO:0050896	response to stimulus	Anpep	Gclc	Gclm	Gctg	Ggt1	Ggt2	Ggt5	Ggt6	Ggt7	Gss	Oplah

Full set of annotations for PWY-4041

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0017168	5-oxoprolinase (ATP-hydrolyzing) activity	Oplah	IEA	color key
Molecular Function	GO:0008415	acyltransferase activity	Ggt5	IEA	color key
Molecular Function	GO:0008415	acyltransferase activity	Ggt7	IEA	color key
Molecular Function	GO:0008415	acyltransferase activity	Ggt6	IEA	color key
Molecular Function	GO:0008415	acyltransferase activity	Ggct	IEA	color key
Molecular Function	GO:0008415	acyltransferase activity	Ggt1	IEA	color key
Molecular Function	GO:0004177	aminopeptidase activity	Anpep	IDA	color key
Molecular Function	GO:0005524	ATP binding	Gss	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Oplah	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Gss	IEA	color key
Molecular Function	GO:0003839	gamma-glutamylcyclotransferase activity	Ggct	IEA	color key
Molecular Function	GO:0003840	gamma-glutamyltransferase activity	Ggt5	IDA	color key
Molecular Function	GO:0003840	gamma-glutamyltransferase activity	Ggt5	IMP	color key
Molecular Function	GO:0003840	gamma-glutamyltransferase activity	Ggt7	IEA	color key
Molecular Function	GO:0003840	gamma-glutamyltransferase activity	Ggt6	IEA	color key
Molecular Function	GO:0003840	gamma-glutamyltransferase activity	Ggt1	TAS	color key
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	Gclc	IDA	color key
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	Gclc	IMP	color key
Molecular Function	GO:0035226	glutamate-cysteine ligase catalytic subunit binding	Gclm	IDA	color key
Molecular Function	GO:0004363	glutathione synthase activity	Gss	IDA	color key
Molecular Function	GO:0016787	hydrolase activity	Oplah	IEA	color key
Molecular Function	GO:0016787	hydrolase activity	Anpep	IEA	color key
Molecular Function	GO:0016874	ligase activity	Gclc	IEA	color key
Molecular Function	GO:0016874	ligase activity	Gss	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Anpep	IEA	color key
Molecular Function	GO:0008237	metallopeptidase activity	Anpep	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Gss	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Gclm	IEA	color key
Molecular Function	GO:0008233	peptidase activity	Anpep	IEA	color key
Molecular Function	GO:0046982	protein heterodimerization activity	Gclc	IPI	color key
Molecular Function	GO:0046982	protein heterodimerization activity	Gclm	IPI	color key
Molecular Function	GO:0016740	transferase activity	Ggt5	IEA	color key
Molecular Function	GO:0016740	transferase activity	Ggt7	IEA	color key
Molecular Function	GO:0016740	transferase activity	Ggt6	IEA	color key
Molecular Function	GO:0016740	transferase activity	Ggct	IEA	color key
Molecular Function	GO:0016740	transferase activity	Ggt1	IEA	color key
Molecular Function	GO:0008270	zinc ion binding	Anpep	IEA	color key
Cellular Component	GO:0005829	cytosol	Gclc	IDA	color key
Cellular Component	GO:0017109	glutamate-cysteine ligase complex	Gclc	IDA	color key
Cellular Component	GO:0017109	glutamate-cysteine ligase complex	Gclm	IDA	color key
Cellular Component	GO:0016021	integral to membrane	Ggt5	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Ggt7	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Ggt6	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Ggt1	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Anpep	IEA	color key
Cellular Component	GO:0005887	integral to plasma membrane	Ggt1	TAS	color key
Cellular Component	GO:0016020	membrane	Ggt5	IEA	color key
Cellular Component	GO:0016020	membrane	Ggt7	IEA	color key
Cellular Component	GO:0016020	membrane	Ggt6	IEA	color key
Cellular Component	GO:0016020	membrane	Ggt1	IEA	color key
Cellular Component	GO:0016020	membrane	Anpep	IEA	color key
Cellular Component	GO:0005886	plasma membrane	Ggt5	IDA	color key
Biological Process	GO:0001525	angiogenesis	Anpep	IEA	color key
Biological Process	GO:0030154	cell differentiation	Anpep	IEA	color key
Biological Process	GO:0006534	cysteine metabolic process	Gclm	IMP	color key
Biological Process	GO:0006750	glutathione biosynthetic process	Gclc	IDA	color key
Biological Process	GO:0006750	glutathione biosynthetic process	Gclc	IMP	color key
Biological Process	GO:0006750	glutathione biosynthetic process	Gclm	IDA	color key
Biological Process	GO:0006750	glutathione biosynthetic process	Ggt5	IEA	color key
Biological Process	GO:0006750	glutathione biosynthetic process	Ggt7	IEA	color key
Biological Process	GO:0006750	glutathione biosynthetic process	Ggt6	IEA	color key
Biological Process	GO:0006750	glutathione biosynthetic process	Ggt1	IEA	color key
Biological Process	GO:0006750	glutathione biosynthetic process	Gss	IEA	color key
Biological Process	GO:0006749	glutathione metabolic process	Gclc	IMP	color key
Biological Process	GO:0006749	glutathione metabolic process	Gclm	IMP	color key
Biological Process	GO:0006749	glutathione metabolic process	Ggt1	TAS	color key
Biological Process	GO:0006954	inflammatory response	Ggt5	IMP	color key
Biological Process	GO:0019852	L-ascorbic acid metabolic process	Gclc	IMP	color key
Biological Process	GO:0019370	leukotriene biosynthetic process	Ggt5	IMP	color key
Biological Process	GO:0007275	multicellular organismal development	Anpep	IEA	color key
Biological Process	GO:0043066	negative regulation of apoptosis	Gclc	IGI	color key
Biological Process	GO:0043066	negative regulation of apoptosis	Gclm	IGI	color key
Biological Process	GO:0031397	negative regulation of protein ubiquitination	Gclc	IMP	color key
Biological Process	GO:0055114	oxidation reduction	Gclm	IEA	color key
Biological Process	GO:0035229	positive regulation of glutamate-cysteine ligase activity	Gclm	IDA	color key
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Gclc	IMP	color key
Biological Process	GO:0006508	proteolysis	Anpep	IEA	color key
Biological Process	GO:0051900	regulation of mitochondrial depolarization	Gclc	IGI	color key
Biological Process	GO:0051900	regulation of mitochondrial depolarization	Gclm	IGI	color key
Biological Process	GO:0046685	response to arsenic	Gclc	IMP	color key
Biological Process	GO:0046686	response to cadmium ion	Gss	IDA	color key
Biological Process	GO:0006979	response to oxidative stress	Gclm	IMP	color key
Biological Process	GO:0009410	response to xenobiotic stimulus	Gclc	IMP	color key
Biological Process	GO:0007283	spermatogenesis	Ggt1	IMP	color key