MGI MouseCyc GO annotations for PWY-4081

MGI MouseCyc GO annotations for PWY-4081: glutathione redox reactions I

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY-4081.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Molecular Function	GO:0016209	antioxidant activity	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Molecular Function	GO:0005488	binding	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Molecular Function	GO:0003824	catalytic activity	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Molecular Function	GO:0009055	electron carrier activity	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Cellular Component	GO:0005623	cell	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Cellular Component	GO:0044464	cell part	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Cellular Component	GO:0031975	envelope	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Cellular Component	GO:0005576	extracellular region	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Cellular Component	GO:0043226	organelle	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Cellular Component	GO:0044422	organelle part	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0065007	biological regulation	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0009987	cellular process	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0032502	developmental process	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0040007	growth	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0002376	immune system process	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0051179	localization	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0040011	locomotion	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0008152	metabolic process	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0051704	multi-organism process	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0032501	multicellular organismal process	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0048519	negative regulation of biological process	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0048518	positive regulation of biological process	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0050789	regulation of biological process	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0000003	reproduction	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0022414	reproductive process	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr
Biological Process	GO:0050896	response to stimulus	2310016C16Rik	Gpx1	Gpx2	Gpx3	Gpx4	Gpx5	Gpx6	Gpx7	Gsr

Full set of annotations for PWY-4081

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0009055	electron carrier activity	Gsr	IEA	color key
Molecular Function	GO:0050660	FAD binding	Gsr	IEA	color key
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx4	IDA	color key
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx4	ISO	color key
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx5	IEA	color key
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx1	IDA	color key
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx1	IMP	color key
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx3	IDA	color key
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx2	IMP	color key
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx2	ISS	color key
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx7	IEA	color key
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx8	IEA	color key
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx6	IEA	color key
Molecular Function	GO:0004362	glutathione-disulfide reductase activity	Gsr	IDA	color key
Molecular Function	GO:0050661	NADP binding	Gsr	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Gpx4	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Gpx5	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Gpx1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Gpx3	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Gpx2	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Gpx7	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Gpx8	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Gpx6	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Gsr	IEA	color key
Molecular Function	GO:0004601	peroxidase activity	Gpx4	IEA	color key
Molecular Function	GO:0004601	peroxidase activity	Gpx5	IEA	color key
Molecular Function	GO:0004601	peroxidase activity	Gpx1	IEA	color key
Molecular Function	GO:0004601	peroxidase activity	Gpx3	IEA	color key
Molecular Function	GO:0004601	peroxidase activity	Gpx2	IEA	color key
Molecular Function	GO:0004601	peroxidase activity	Gpx7	IEA	color key
Molecular Function	GO:0004601	peroxidase activity	Gpx8	IEA	color key
Molecular Function	GO:0004601	peroxidase activity	Gpx6	IEA	color key
Molecular Function	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity	Gpx4	IEA	color key
Molecular Function	GO:0008430	selenium binding	Gpx4	IEA	color key
Molecular Function	GO:0008430	selenium binding	Gpx1	IEA	color key
Molecular Function	GO:0008430	selenium binding	Gpx3	IEA	color key
Molecular Function	GO:0008430	selenium binding	Gpx2	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Gpx4	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Gpx1	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Gpx2	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Gsr	IEA	color key
Cellular Component	GO:0005829	cytosol	Gpx4	IDA	color key
Cellular Component	GO:0005829	cytosol	Gpx2	TAS	color key
Cellular Component	GO:0009897	external side of plasma membrane	Gsr	IDA	color key
Cellular Component	GO:0005576	extracellular region	Gpx5	IEA	color key
Cellular Component	GO:0005576	extracellular region	Gpx3	IEA	color key
Cellular Component	GO:0005576	extracellular region	Gpx7	IEA	color key
Cellular Component	GO:0005576	extracellular region	Gpx6	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Gpx8	IEA	color key
Cellular Component	GO:0016020	membrane	Gpx8	IEA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Gpx4	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Gpx4	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Gpx1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Gpx1	IMP	color key
Cellular Component	GO:0005739	mitochondrion	Gsr	IDA	color key
Cellular Component	GO:0005635	nuclear envelope	Gpx4	IDA	color key
Cellular Component	GO:0005634	nucleus	Gpx4	IDA	color key
Biological Process	GO:0060055	angiogenesis involved in wound healing	Gpx1	IMP	color key
Biological Process	GO:0006915	apoptosis	Gpx1	IMP	color key
Biological Process	GO:0043534	blood vessel endothelial cell migration	Gpx1	IMP	color key
Biological Process	GO:0008283	cell proliferation	Gpx1	IMP	color key
Biological Process	GO:0045454	cell redox homeostasis	Gsr	IEA	color key
Biological Process	GO:0001885	endothelial cell development	Gpx1	IMP	color key
Biological Process	GO:0006325	establishment or maintenance of chromatin architecture	Gpx4	IDA	color key
Biological Process	GO:0045444	fat cell differentiation	Gpx1	IMP	color key
Biological Process	GO:0006749	glutathione metabolic process	Gsr	IC	color key
Biological Process	GO:0060047	heart contraction	Gpx1	IMP	color key
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Gpx1	IMP	color key
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Gpx3	IDA	color key
Biological Process	GO:0006917	induction of apoptosis	Gpx1	IMP	color key
Biological Process	GO:0008631	induction of apoptosis by oxidative stress	Gpx1	IMP	color key
Biological Process	GO:0051702	interaction with symbiont	Gpx1	IGI	color key
Biological Process	GO:0051702	interaction with symbiont	Gpx2	IGI	color key
Biological Process	GO:0006629	lipid metabolic process	Gpx1	IMP	color key
Biological Process	GO:0007275	multicellular organismal development	Gpx4	IEA	color key
Biological Process	GO:0051450	myoblast proliferation	Gpx1	IMP	color key
Biological Process	GO:0014902	myotube differentiation	Gpx1	IMP	color key
Biological Process	GO:0043066	negative regulation of apoptosis	Gpx1	IMP	color key
Biological Process	GO:0002862	negative regulation of inflammatory response to antigenic stimulus	Gpx1	IGI	color key
Biological Process	GO:0002862	negative regulation of inflammatory response to antigenic stimulus	Gpx2	IGI	color key
Biological Process	GO:0055114	oxidation reduction	Gpx4	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Gpx5	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Gpx1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Gpx3	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Gpx2	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Gpx7	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Gpx8	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Gpx6	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Gsr	IEA	color key
Biological Process	GO:0051897	positive regulation of protein kinase B signaling cascade	Gpx1	IMP	color key
Biological Process	GO:0018158	protein amino acid oxidation	Gpx1	IMP	color key
Biological Process	GO:0043523	regulation of neuron apoptosis	Gpx1	IMP	color key
Biological Process	GO:0010332	response to gamma radiation	Gpx1	IGI	color key
Biological Process	GO:0042542	response to hydrogen peroxide	Gpx1	IMP	color key
Biological Process	GO:0033194	response to hydroperoxide	Gpx1	IMP	color key
Biological Process	GO:0006979	response to oxidative stress	Gpx4	IEA	color key
Biological Process	GO:0006979	response to oxidative stress	Gpx5	IEA	color key
Biological Process	GO:0006979	response to oxidative stress	Gpx1	IGI	color key
Biological Process	GO:0006979	response to oxidative stress	Gpx1	IMP	color key
Biological Process	GO:0006979	response to oxidative stress	Gpx3	IEA	color key
Biological Process	GO:0006979	response to oxidative stress	Gpx2	IEA	color key
Biological Process	GO:0006979	response to oxidative stress	Gpx7	IEA	color key
Biological Process	GO:0006979	response to oxidative stress	Gpx8	IEA	color key
Biological Process	GO:0006979	response to oxidative stress	Gpx6	IEA	color key
Biological Process	GO:0000302	response to reactive oxygen species	Gpx1	IMP	color key
Biological Process	GO:0009609	response to symbiotic bacterium	Gpx1	IGI	color key
Biological Process	GO:0009609	response to symbiotic bacterium	Gpx2	IGI	color key
Biological Process	GO:0009636	response to toxin	Gpx1	IMP	color key
Biological Process	GO:0009611	response to wounding	Gpx1	IMP	color key
Biological Process	GO:0009410	response to xenobiotic stimulus	Gpx1	IMP	color key
Biological Process	GO:0007605	sensory perception of sound	Gpx1	IMP	color key
Biological Process	GO:0048741	skeletal muscle fiber development	Gpx1	IMP	color key
Biological Process	GO:0043403	skeletal muscle regeneration	Gpx1	IMP	color key
Biological Process	GO:0007283	spermatogenesis	Gpx4	IDA	color key
Biological Process	GO:0001659	temperature homeostasis	Gpx1	IGI	color key
Biological Process	GO:0001659	temperature homeostasis	Gpx2	IGI	color key
Biological Process	GO:0006641	triacylglycerol metabolic process	Gpx1	IMP	color key
Biological Process	GO:0042311	vasodilation	Gpx1	IMP	color key