MGI MouseCyc GO annotations for PWY-5690

MGI MouseCyc GO annotations for PWY-5690: TCA cycle variation III (eukaryotic)

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY-5690.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Molecular Function	GO:0005488	binding	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Molecular Function	GO:0003824	catalytic activity	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Molecular Function	GO:0009055	electron carrier activity	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0005623	cell	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0044464	cell part	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0031975	envelope	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0032991	macromolecular complex	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0043226	organelle	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Cellular Component	GO:0044422	organelle part	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0065007	biological regulation	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0009987	cellular process	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0032502	developmental process	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0051234	establishment of localization	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0051179	localization	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0008152	metabolic process	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0032501	multicellular organismal process	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2
Biological Process	GO:0050789	regulation of biological process	4933405O20Rik	Aco1	Aco2	Cs	Csl	Fh1	Idh3a	Idh3b	Idh3g	Mdh1	Mdh1b	Mdh2	Sdha	Sdhb	Sdhc	Sdhd	Sucla2	Suclg1	Suclg2

Full set of annotations for PWY-5690

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0051537	2 iron, 2 sulfur cluster binding	Sdhb	IEA	color key
Molecular Function	GO:0051538	3 iron, 4 sulfur cluster binding	Sdhb	IEA	color key
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	Sdhb	IEA	color key
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	Aco1	IEA	color key
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	Aco2	IEA	color key
Molecular Function	GO:0003994	aconitate hydratase activity	Aco1	IDA	color key
Molecular Function	GO:0003994	aconitate hydratase activity	Aco2	IDA	color key
Molecular Function	GO:0005524	ATP binding	Idh3g	IEA	color key
Molecular Function	GO:0005524	ATP binding	Sucla2	IEA	color key
Molecular Function	GO:0005524	ATP binding	Suclg2	IEA	color key
Molecular Function	GO:0003878	ATP citrate synthase activity	Suclg1	IEA	color key
Molecular Function	GO:0005488	binding	Mdh1b	IEA	color key
Molecular Function	GO:0005488	binding	Suclg1	IEA	color key
Molecular Function	GO:0005488	binding	Mdh2	IEA	color key
Molecular Function	GO:0005488	binding	Mdh1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Sucla2	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Suclg2	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Mdh1b	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Suclg1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Fh1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Mdh2	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Mdh1	IEA	color key
Molecular Function	GO:0004108	citrate (Si)-synthase activity	Cs	ISA	color key
Molecular Function	GO:0009055	electron carrier activity	Sdhc	IEA	color key
Molecular Function	GO:0009055	electron carrier activity	Sdha	IEA	color key
Molecular Function	GO:0009055	electron carrier activity	Sdhb	IEA	color key
Molecular Function	GO:0050660	FAD binding	Sdha	IEA	color key
Molecular Function	GO:0004333	fumarate hydratase activity	Fh1	IEA	color key
Molecular Function	GO:0005525	GTP binding	Suclg1	IEA	color key
Molecular Function	GO:0020037	heme binding	Sdhd	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Sdhc	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Sdhd	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Sdhb	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Aco1	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Aco2	ISO	color key
Molecular Function	GO:0030350	iron-responsive element binding	Aco1	IDA	color key
Molecular Function	GO:0051536	iron-sulfur cluster binding	Sdhb	IEA	color key
Molecular Function	GO:0051536	iron-sulfur cluster binding	Aco1	IEA	color key
Molecular Function	GO:0051536	iron-sulfur cluster binding	Aco2	IEA	color key
Molecular Function	GO:0004449	isocitrate dehydrogenase (NAD+) activity	Idh3g	IEA	color key
Molecular Function	GO:0004449	isocitrate dehydrogenase (NAD+) activity	Idh3a	IEA	color key
Molecular Function	GO:0030060	L-malate dehydrogenase activity	Mdh2	IDA	color key
Molecular Function	GO:0030060	L-malate dehydrogenase activity	Mdh1	IEA	color key
Molecular Function	GO:0016874	ligase activity	Sucla2	IEA	color key
Molecular Function	GO:0016874	ligase activity	Suclg2	IEA	color key
Molecular Function	GO:0016874	ligase activity	Suclg1	IEA	color key
Molecular Function	GO:0016829	lyase activity	Aco1	IEA	color key
Molecular Function	GO:0016829	lyase activity	Aco2	IEA	color key
Molecular Function	GO:0016829	lyase activity	Fh1	IEA	color key
Molecular Function	GO:0000287	magnesium ion binding	Idh3g	IEA	color key
Molecular Function	GO:0000287	magnesium ion binding	Idh3a	IEA	color key
Molecular Function	GO:0016615	malate dehydrogenase activity	Mdh1b	IEA	color key
Molecular Function	GO:0016615	malate dehydrogenase activity	Mdh2	ISA	color key
Molecular Function	GO:0016615	malate dehydrogenase activity	Mdh1	IEA	color key
Molecular Function	GO:0030145	manganese ion binding	Idh3g	IEA	color key
Molecular Function	GO:0030145	manganese ion binding	Idh3a	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Idh3g	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Sdhc	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Sdhd	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Sdhb	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Idh3a	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Aco1	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Aco2	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Idh3g	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Suclg1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Idh3g	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Sdha	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Sdhb	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Idh3a	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Mdh1b	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Mdh2	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Mdh1	IEA	color key
Molecular Function	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	Sdha	IEA	color key
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Idh3g	IEA	color key
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Idh3a	IEA	color key
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Mdh2	IEA	color key
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Mdh1	IEA	color key
Molecular Function	GO:0005515	protein binding	Cs	ISA	color key
Molecular Function	GO:0005515	protein binding	Mdh2	ISA	color key
Molecular Function	GO:0003723	RNA binding	Aco1	IEA	color key
Molecular Function	GO:0008177	succinate dehydrogenase (ubiquinone) activity	Sdha	IEA	color key
Molecular Function	GO:0008177	succinate dehydrogenase (ubiquinone) activity	Sdhb	IEA	color key
Molecular Function	GO:0000104	succinate dehydrogenase activity	Sdhc	IEA	color key
Molecular Function	GO:0004775	succinate-CoA ligase (ADP-forming) activity	Sucla2	IEA	color key
Molecular Function	GO:0004775	succinate-CoA ligase (ADP-forming) activity	Suclg1	IEA	color key
Molecular Function	GO:0004776	succinate-CoA ligase (GDP-forming) activity	Suclg2	IEA	color key
Molecular Function	GO:0004776	succinate-CoA ligase (GDP-forming) activity	Suclg1	IEA	color key
Molecular Function	GO:0004774	succinate-CoA ligase activity	Sucla2	ISS	color key
Molecular Function	GO:0004777	succinate-semialdehyde dehydrogenase activity	Suclg2	ISA	color key
Molecular Function	GO:0016740	transferase activity	Cs	IEA	color key
Molecular Function	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	Cs	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Aco1	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Fh1	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Mdh1	IEA	color key
Cellular Component	GO:0005829	cytosol	Aco1	IDA	color key
Cellular Component	GO:0005829	cytosol	Mdh1	ISO	color key
Cellular Component	GO:0005783	endoplasmic reticulum	Aco1	ISO	color key
Cellular Component	GO:0005794	Golgi apparatus	Aco1	ISO	color key
Cellular Component	GO:0016021	integral to membrane	Sdhc	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Sdhd	IEA	color key
Cellular Component	GO:0016020	membrane	Sdhc	IEA	color key
Cellular Component	GO:0016020	membrane	Sdhd	IEA	color key
Cellular Component	GO:0016020	membrane	Sdha	IEA	color key
Cellular Component	GO:0016020	membrane	Sdhb	IEA	color key
Cellular Component	GO:0005740	mitochondrial envelope	Sdhd	IEA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Sdhc	IEA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Sdhd	IEA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Sdha	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Sdhb	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Suclg1	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Mdh2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Idh3g	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Sucla2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Suclg2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Sdhc	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Sdhd	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Sdha	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Sdhb	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Idh3a	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Suclg1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Idh3b	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Aco2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Cs	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Cs	ISA	color key
Cellular Component	GO:0005739	mitochondrion	Fh1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Mdh2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Mdh2	ISA	color key
Cellular Component	GO:0045239	tricarboxylic acid cycle enzyme complex	Fh1	IEA	color key
Biological Process	GO:0005975	carbohydrate metabolic process	Mdh1b	IEA	color key
Biological Process	GO:0005975	carbohydrate metabolic process	Mdh2	IEA	color key
Biological Process	GO:0005975	carbohydrate metabolic process	Mdh1	IEA	color key
Biological Process	GO:0044262	cellular carbohydrate metabolic process	Cs	IEA	color key
Biological Process	GO:0044262	cellular carbohydrate metabolic process	Mdh2	IEA	color key
Biological Process	GO:0044262	cellular carbohydrate metabolic process	Mdh1	IEA	color key
Biological Process	GO:0006879	cellular iron ion homeostasis	Aco1	IGI	color key
Biological Process	GO:0006879	cellular iron ion homeostasis	Aco1	IMP	color key
Biological Process	GO:0006101	citrate metabolic process	Aco2	ISO	color key
Biological Process	GO:0022900	electron transport chain	Sdhc	IEA	color key
Biological Process	GO:0022900	electron transport chain	Sdhd	IEA	color key
Biological Process	GO:0022900	electron transport chain	Sdha	IEA	color key
Biological Process	GO:0022900	electron transport chain	Sdhb	IEA	color key
Biological Process	GO:0006106	fumarate metabolic process	Fh1	IEA	color key
Biological Process	GO:0006096	glycolysis	Mdh2	IEA	color key
Biological Process	GO:0006096	glycolysis	Mdh1	IEA	color key
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Fh1	IMP	color key
Biological Process	GO:0050892	intestinal absorption	Aco1	IGI	color key
Biological Process	GO:0006108	malate metabolic process	Mdh1b	IEA	color key
Biological Process	GO:0006108	malate metabolic process	Mdh2	ISA	color key
Biological Process	GO:0006108	malate metabolic process	Mdh1	IEA	color key
Biological Process	GO:0008152	metabolic process	Idh3g	IEA	color key
Biological Process	GO:0008152	metabolic process	Sucla2	IEA	color key
Biological Process	GO:0008152	metabolic process	Suclg2	IEA	color key
Biological Process	GO:0008152	metabolic process	Idh3a	IEA	color key
Biological Process	GO:0008152	metabolic process	Mdh1b	IEA	color key
Biological Process	GO:0008152	metabolic process	Suclg1	IEA	color key
Biological Process	GO:0008152	metabolic process	Aco1	IEA	color key
Biological Process	GO:0008152	metabolic process	Aco2	IEA	color key
Biological Process	GO:0008152	metabolic process	Mdh2	IEA	color key
Biological Process	GO:0008152	metabolic process	Mdh1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Idh3g	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Sdha	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Sdhb	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Idh3a	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Mdh1b	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Mdh2	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Mdh1	IEA	color key
Biological Process	GO:0009791	post-embryonic development	Aco1	IGI	color key
Biological Process	GO:0010468	regulation of gene expression	Aco1	IGI	color key
Biological Process	GO:0006417	regulation of translation	Aco1	IMP	color key
Biological Process	GO:0006810	transport	Sdhc	IEA	color key
Biological Process	GO:0006810	transport	Sdhd	IEA	color key
Biological Process	GO:0006810	transport	Sdha	IEA	color key
Biological Process	GO:0006810	transport	Sdhb	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Idh3g	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Sucla2	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Suclg2	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Sdhc	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Sdhd	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Sdha	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Sdhb	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Idh3a	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Mdh1b	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Suclg1	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Aco1	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Aco2	ISO	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Cs	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Fh1	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Mdh2	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Mdh1	IEA	color key