MGI MouseCyc GO annotations for PWY-5750

MGI MouseCyc GO annotations for PWY-5750: itaconate biosynthesis

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY-5750.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Aco1	Aco2	Cs	Csl	Pcx
Molecular Function	GO:0005488	binding	Aco1	Aco2	Cs	Csl	Pcx
Molecular Function	GO:0003824	catalytic activity	Aco1	Aco2	Cs	Csl	Pcx
Cellular Component	GO:0005623	cell	Aco1	Aco2	Cs	Csl	Pcx
Cellular Component	GO:0044464	cell part	Aco1	Aco2	Cs	Csl	Pcx
Cellular Component	GO:0031975	envelope	Aco1	Aco2	Cs	Csl	Pcx
Cellular Component	GO:0043226	organelle	Aco1	Aco2	Cs	Csl	Pcx
Cellular Component	GO:0044422	organelle part	Aco1	Aco2	Cs	Csl	Pcx
Biological Process	GO:0065007	biological regulation	Aco1	Aco2	Cs	Csl	Pcx
Biological Process	GO:0009987	cellular process	Aco1	Aco2	Cs	Csl	Pcx
Biological Process	GO:0032502	developmental process	Aco1	Aco2	Cs	Csl	Pcx
Biological Process	GO:0008152	metabolic process	Aco1	Aco2	Cs	Csl	Pcx
Biological Process	GO:0032501	multicellular organismal process	Aco1	Aco2	Cs	Csl	Pcx
Biological Process	GO:0050789	regulation of biological process	Aco1	Aco2	Cs	Csl	Pcx

Full set of annotations for PWY-5750

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	Aco1	IEA	color key
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	Aco2	IEA	color key
Molecular Function	GO:0003994	aconitate hydratase activity	Aco1	IDA	color key
Molecular Function	GO:0003994	aconitate hydratase activity	Aco2	IDA	color key
Molecular Function	GO:0005524	ATP binding	Pcx	IEA	color key
Molecular Function	GO:0009374	biotin binding	Pcx	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Pcx	IEA	color key
Molecular Function	GO:0004108	citrate (Si)-synthase activity	Cs	ISA	color key
Molecular Function	GO:0005506	iron ion binding	Aco1	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Aco2	ISO	color key
Molecular Function	GO:0030350	iron-responsive element binding	Aco1	IDA	color key
Molecular Function	GO:0051536	iron-sulfur cluster binding	Aco1	IEA	color key
Molecular Function	GO:0051536	iron-sulfur cluster binding	Aco2	IEA	color key
Molecular Function	GO:0016874	ligase activity	Pcx	IEA	color key
Molecular Function	GO:0016829	lyase activity	Aco1	IEA	color key
Molecular Function	GO:0016829	lyase activity	Aco2	IEA	color key
Molecular Function	GO:0030145	manganese ion binding	Pcx	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Aco1	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Aco2	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Pcx	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Pcx	IEA	color key
Molecular Function	GO:0005515	protein binding	Cs	ISA	color key
Molecular Function	GO:0004736	pyruvate carboxylase activity	Pcx	IEA	color key
Molecular Function	GO:0003723	RNA binding	Aco1	IEA	color key
Molecular Function	GO:0016740	transferase activity	Cs	IEA	color key
Molecular Function	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	Cs	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Aco1	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Pcx	IEA	color key
Cellular Component	GO:0005829	cytosol	Aco1	IDA	color key
Cellular Component	GO:0005783	endoplasmic reticulum	Aco1	ISO	color key
Cellular Component	GO:0005794	Golgi apparatus	Aco1	ISO	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Pcx	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Aco2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Cs	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Cs	ISA	color key
Cellular Component	GO:0005739	mitochondrion	Pcx	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Pcx	ISO	color key
Biological Process	GO:0044262	cellular carbohydrate metabolic process	Cs	IEA	color key
Biological Process	GO:0006879	cellular iron ion homeostasis	Aco1	IGI	color key
Biological Process	GO:0006879	cellular iron ion homeostasis	Aco1	IMP	color key
Biological Process	GO:0006101	citrate metabolic process	Aco2	ISO	color key
Biological Process	GO:0006094	gluconeogenesis	Pcx	IEA	color key
Biological Process	GO:0050892	intestinal absorption	Aco1	IGI	color key
Biological Process	GO:0008610	lipid biosynthetic process	Pcx	IEA	color key
Biological Process	GO:0008152	metabolic process	Aco1	IEA	color key
Biological Process	GO:0008152	metabolic process	Aco2	IEA	color key
Biological Process	GO:0008152	metabolic process	Pcx	IEA	color key
Biological Process	GO:0009791	post-embryonic development	Aco1	IGI	color key
Biological Process	GO:0010468	regulation of gene expression	Aco1	IGI	color key
Biological Process	GO:0006417	regulation of translation	Aco1	IMP	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Aco1	IEA	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Aco2	ISO	color key
Biological Process	GO:0006099	tricarboxylic acid cycle	Cs	IEA	color key