MGI MouseCyc GO annotations for PWY-841

MGI MouseCyc GO annotations for PWY-841: purine nucleotides de novo biosynthesis II

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY-841.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Molecular Function	GO:0005488	binding	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Molecular Function	GO:0003824	catalytic activity	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Molecular Function	GO:0060089	molecular transducer activity	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Cellular Component	GO:0005623	cell	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Cellular Component	GO:0044464	cell part	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Cellular Component	GO:0032991	macromolecular complex	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Biological Process	GO:0065007	biological regulation	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Biological Process	GO:0009987	cellular process	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Biological Process	GO:0002376	immune system process	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Biological Process	GO:0008152	metabolic process	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Biological Process	GO:0032501	multicellular organismal process	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Biological Process	GO:0048518	positive regulation of biological process	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat
Biological Process	GO:0050789	regulation of biological process	Adsl	Adss	Adssl1	Atic	Gart	Gmps	Ifnar1	Impdh1	Impdh2	Paics	Pfas	Ppat

Full set of annotations for PWY-841

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0004018	adenylosuccinate lyase activity	Adsl	ISA	color key
Molecular Function	GO:0004019	adenylosuccinate synthase activity	Adssl1	IDA	color key
Molecular Function	GO:0004019	adenylosuccinate synthase activity	Adss	IDA	color key
Molecular Function	GO:0005524	ATP binding	Paics	IEA	color key
Molecular Function	GO:0005524	ATP binding	Gmps	IEA	color key
Molecular Function	GO:0005524	ATP binding	Gart	IEA	color key
Molecular Function	GO:0016831	carboxy-lyase activity	Paics	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Adsl	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Impdh2	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Atic	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Paics	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Gmps	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Gart	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Impdh1	IEA	color key
Molecular Function	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	Gmps	IEA	color key
Molecular Function	GO:0003921	GMP synthase activity	Gmps	ISO	color key
Molecular Function	GO:0005525	GTP binding	Adssl1	IEA	color key
Molecular Function	GO:0005525	GTP binding	Adss	IEA	color key
Molecular Function	GO:0016787	hydrolase activity	Atic	IEA	color key
Molecular Function	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	Gart	IEA	color key
Molecular Function	GO:0003937	IMP cyclohydrolase activity	Atic	IEA	color key
Molecular Function	GO:0003938	IMP dehydrogenase activity	Impdh2	IDA	color key
Molecular Function	GO:0003938	IMP dehydrogenase activity	Impdh1	IDA	color key
Molecular Function	GO:0004904	interferon receptor activity	Ifnar1	IMP	color key
Molecular Function	GO:0016874	ligase activity	Paics	IEA	color key
Molecular Function	GO:0016874	ligase activity	Gmps	IEA	color key
Molecular Function	GO:0016874	ligase activity	Adssl1	IEA	color key
Molecular Function	GO:0016874	ligase activity	Adss	IEA	color key
Molecular Function	GO:0016874	ligase activity	Gart	IEA	color key
Molecular Function	GO:0016829	lyase activity	Adsl	IEA	color key
Molecular Function	GO:0016829	lyase activity	Paics	IEA	color key
Molecular Function	GO:0000287	magnesium ion binding	Adssl1	IEA	color key
Molecular Function	GO:0000287	magnesium ion binding	Adss	IEA	color key
Molecular Function	GO:0030145	manganese ion binding	Gart	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Impdh2	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Adssl1	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Adss	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Gart	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Impdh1	IEA	color key
Molecular Function	GO:0008168	methyltransferase activity	Gart	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Gmps	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Adssl1	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Adss	IEA	color key
Molecular Function	GO:0000166	nucleotide binding	Gart	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Impdh2	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Impdh1	IEA	color key
Molecular Function	GO:0004637	phosphoribosylamine-glycine ligase activity	Ifnar1	IEA	color key
Molecular Function	GO:0004637	phosphoribosylamine-glycine ligase activity	Gart	IEA	color key
Molecular Function	GO:0004638	phosphoribosylaminoimidazole carboxylase activity	Paics	IEA	color key
Molecular Function	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	Atic	IEA	color key
Molecular Function	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	Paics	IEA	color key
Molecular Function	GO:0004641	phosphoribosylformylglycinamidine cyclo-ligase activity	Gart	IEA	color key
Molecular Function	GO:0004644	phosphoribosylglycinamide formyltransferase activity	Gart	IEA	color key
Molecular Function	GO:0030955	potassium ion binding	Impdh2	IEA	color key
Molecular Function	GO:0030955	potassium ion binding	Impdh1	IEA	color key
Molecular Function	GO:0005515	protein binding	Ifnar1	IPI	color key
Molecular Function	GO:0005515	protein binding	Adssl1	IPI	color key
Molecular Function	GO:0004872	receptor activity	Ifnar1	IEA	color key
Molecular Function	GO:0016740	transferase activity	Atic	IEA	color key
Molecular Function	GO:0016740	transferase activity	Ppat	IEA	color key
Molecular Function	GO:0016740	transferase activity	Pfas	IEA	color key
Molecular Function	GO:0016740	transferase activity	Gart	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Gmps	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Adssl1	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Adss	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Gart	IEA	color key
Cellular Component	GO:0005829	cytosol	Gmps	ISO	color key
Cellular Component	GO:0016021	integral to membrane	Ifnar1	IEA	color key
Cellular Component	GO:0016020	membrane	Ifnar1	IEA	color key
Cellular Component	GO:0016020	membrane	Adssl1	IEA	color key
Cellular Component	GO:0009320	phosphoribosylaminoimidazole carboxylase complex	Paics	IEA	color key
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	Paics	IEA	color key
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	Gart	IEA	color key
Biological Process	GO:0006167	AMP biosynthetic process	Adss	IDA	color key
Biological Process	GO:0009058	biosynthetic process	Gmps	IEA	color key
Biological Process	GO:0009058	biosynthetic process	Gart	IEA	color key
Biological Process	GO:0006541	glutamine metabolic process	Gmps	IEA	color key
Biological Process	GO:0006177	GMP biosynthetic process	Impdh2	IEA	color key
Biological Process	GO:0006177	GMP biosynthetic process	Gmps	ISO	color key
Biological Process	GO:0006177	GMP biosynthetic process	Impdh1	IEA	color key
Biological Process	GO:0006188	IMP biosynthetic process	Atic	IEA	color key
Biological Process	GO:0046651	lymphocyte proliferation	Impdh2	IMP	color key
Biological Process	GO:0046651	lymphocyte proliferation	Impdh1	IMP	color key
Biological Process	GO:0008152	metabolic process	Impdh2	IEA	color key
Biological Process	GO:0008152	metabolic process	Impdh1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Impdh2	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Impdh1	IEA	color key
Biological Process	GO:0032729	positive regulation of interferon-gamma production	Ifnar1	IGI	color key
Biological Process	GO:0009113	purine base biosynthetic process	Gart	IEA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Adsl	IEA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Impdh2	IMP	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Atic	IEA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Paics	IEA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Gmps	IEA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Adssl1	IEA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Adss	IDA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Gart	IEA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Impdh1	IMP	color key
Biological Process	GO:0006163	purine nucleotide metabolic process	Adssl1	IDA	color key
Biological Process	GO:0009152	purine ribonucleotide biosynthetic process	Adsl	IEA	color key
Biological Process	GO:0042110	T cell activation	Ifnar1	IGI	color key
Biological Process	GO:0045351	type I interferon biosynthetic process	Ifnar1	IMP	color key