MGI MouseCyc GO annotations for PWY3DJ-2

MGI MouseCyc GO annotations for PWY3DJ-2: biosynthesis of estrogens

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY3DJ-2.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Molecular Function	GO:0005488	binding	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Molecular Function	GO:0003824	catalytic activity	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Molecular Function	GO:0009055	electron carrier activity	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Cellular Component	GO:0005623	cell	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Cellular Component	GO:0044464	cell part	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Cellular Component	GO:0043226	organelle	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Biological Process	GO:0065007	biological regulation	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Biological Process	GO:0009987	cellular process	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Biological Process	GO:0051234	establishment of localization	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Biological Process	GO:0051179	localization	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Biological Process	GO:0008152	metabolic process	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Biological Process	GO:0051704	multi-organism process	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Biological Process	GO:0000003	reproduction	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1
Biological Process	GO:0022414	reproductive process	Cyp11a1	Cyp17a1	Cyp19a1	Fdx1	Hsd17b1	Hsd17b2	Hsd17b7	Hsd3b1	Hsd3b6	Sult1e1

Full set of annotations for PWY3DJ-2

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0051537	2 iron, 2 sulfur cluster binding	Fdx1	IEA	color key
Molecular Function	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity	Hsd3b6	IEA	color key
Molecular Function	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity	Hsd3b1	IEA	color key
Molecular Function	GO:0000253	3-keto sterol reductase activity	Hsd17b7	IDA	color key
Molecular Function	GO:0050576	3-keto-steroid reductase activity	Hsd17b7	IEA	color key
Molecular Function	GO:0005488	binding	Hsd17b1	IEA	color key
Molecular Function	GO:0005488	binding	Hsd3b6	IEA	color key
Molecular Function	GO:0005488	binding	Hsd17b2	IEA	color key
Molecular Function	GO:0005488	binding	Hsd17b7	IEA	color key
Molecular Function	GO:0005488	binding	Hsd3b1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Hsd17b1	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Hsd3b6	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Hsd17b2	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Hsd17b7	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Hsd3b1	IEA	color key
Molecular Function	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity	Cyp11a1	IDA	color key
Molecular Function	GO:0009055	electron carrier activity	Fdx1	IEA	color key
Molecular Function	GO:0009055	electron carrier activity	Cyp11a1	IEA	color key
Molecular Function	GO:0009055	electron carrier activity	Cyp17a1	IEA	color key
Molecular Function	GO:0009055	electron carrier activity	Cyp19a1	IEA	color key
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase activity	Hsd17b1	IEA	color key
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase activity	Hsd17b2	IEA	color key
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase activity	Hsd17b7	IEA	color key
Molecular Function	GO:0004304	estrone sulfotransferase activity	Sult1e1	IEA	color key
Molecular Function	GO:0020037	heme binding	Cyp11a1	IEA	color key
Molecular Function	GO:0020037	heme binding	Cyp17a1	IEA	color key
Molecular Function	GO:0020037	heme binding	Cyp19a1	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Fdx1	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Cyp11a1	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Cyp17a1	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Cyp19a1	IEA	color key
Molecular Function	GO:0051536	iron-sulfur cluster binding	Fdx1	IEA	color key
Molecular Function	GO:0016853	isomerase activity	Hsd3b6	IEA	color key
Molecular Function	GO:0016853	isomerase activity	Hsd3b1	IEA	color key
Molecular Function	GO:0008289	lipid binding	Sult1e1	IEA	color key
Molecular Function	GO:0016829	lyase activity	Cyp17a1	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Fdx1	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Cyp11a1	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Cyp17a1	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Cyp19a1	IEA	color key
Molecular Function	GO:0004497	monooxygenase activity	Cyp11a1	IEA	color key
Molecular Function	GO:0004497	monooxygenase activity	Cyp17a1	IEA	color key
Molecular Function	GO:0004497	monooxygenase activity	Cyp19a1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Hsd17b1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Hsd3b6	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Hsd17b2	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Hsd17b7	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Cyp11a1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Cyp17a1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Cyp19a1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Hsd3b1	IEA	color key
Molecular Function	GO:0004508	steroid 17-alpha-monooxygenase activity	Cyp17a1	IDA	color key
Molecular Function	GO:0004508	steroid 17-alpha-monooxygenase activity	Cyp17a1	IMP	color key
Molecular Function	GO:0005496	steroid binding	Sult1e1	IEA	color key
Molecular Function	GO:0004769	steroid delta-isomerase activity	Hsd3b6	IEA	color key
Molecular Function	GO:0004769	steroid delta-isomerase activity	Hsd3b1	IEA	color key
Molecular Function	GO:0008146	sulfotransferase activity	Sult1e1	IEA	color key
Molecular Function	GO:0050327	testosterone 17-beta-dehydrogenase activity	Hsd17b2	IEA	color key
Molecular Function	GO:0016740	transferase activity	Sult1e1	IEA	color key
Molecular Function	GO:0050381	unspecific monooxygenase activity	Cyp19a1	IDA	color key
Cellular Component	GO:0030424	axon	Cyp17a1	IDA	color key
Cellular Component	GO:0043025	cell soma	Cyp17a1	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Hsd17b1	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Sult1e1	IEA	color key
Cellular Component	GO:0005783	endoplasmic reticulum	Hsd3b6	IEA	color key
Cellular Component	GO:0005783	endoplasmic reticulum	Hsd17b7	IDA	color key
Cellular Component	GO:0005783	endoplasmic reticulum	Hsd3b1	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Hsd3b6	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Hsd17b2	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Hsd17b7	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Hsd3b1	IEA	color key
Cellular Component	GO:0016020	membrane	Hsd3b6	IEA	color key
Cellular Component	GO:0016020	membrane	Hsd17b2	IEA	color key
Cellular Component	GO:0016020	membrane	Hsd17b7	IEA	color key
Cellular Component	GO:0016020	membrane	Cyp11a1	IEA	color key
Cellular Component	GO:0016020	membrane	Cyp17a1	IEA	color key
Cellular Component	GO:0016020	membrane	Cyp19a1	IEA	color key
Cellular Component	GO:0016020	membrane	Hsd3b1	IEA	color key
Cellular Component	GO:0005739	mitochondrion	Fdx1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Hsd3b6	IEA	color key
Cellular Component	GO:0005739	mitochondrion	Cyp11a1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Cyp17a1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Hsd3b1	IEA	color key
Biological Process	GO:0006700	C21-steroid hormone biosynthetic process	Hsd3b6	IEA	color key
Biological Process	GO:0006700	C21-steroid hormone biosynthetic process	Cyp11a1	IDA	color key
Biological Process	GO:0006700	C21-steroid hormone biosynthetic process	Cyp17a1	IEA	color key
Biological Process	GO:0006700	C21-steroid hormone biosynthetic process	Hsd3b1	IEA	color key
Biological Process	GO:0006695	cholesterol biosynthetic process	Hsd17b7	IDA	color key
Biological Process	GO:0008203	cholesterol metabolic process	Cyp11a1	IEA	color key
Biological Process	GO:0022900	electron transport chain	Fdx1	IEA	color key
Biological Process	GO:0006703	estrogen biosynthetic process	Hsd17b1	IEA	color key
Biological Process	GO:0008210	estrogen metabolic process	Sult1e1	IMP	color key
Biological Process	GO:0007565	female pregnancy	Sult1e1	IMP	color key
Biological Process	GO:0006704	glucocorticoid biosynthetic process	Cyp17a1	IDA	color key
Biological Process	GO:0008610	lipid biosynthetic process	Hsd17b1	IEA	color key
Biological Process	GO:0008610	lipid biosynthetic process	Hsd17b2	IEA	color key
Biological Process	GO:0008610	lipid biosynthetic process	Hsd17b7	IEA	color key
Biological Process	GO:0006629	lipid metabolic process	Cyp11a1	IEA	color key
Biological Process	GO:0008152	metabolic process	Hsd17b1	IEA	color key
Biological Process	GO:0008152	metabolic process	Hsd3b6	IEA	color key
Biological Process	GO:0008152	metabolic process	Hsd17b2	IEA	color key
Biological Process	GO:0008152	metabolic process	Hsd17b7	IEA	color key
Biological Process	GO:0008152	metabolic process	Hsd3b1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Hsd17b1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Hsd3b6	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Hsd17b2	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Hsd17b7	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Cyp11a1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Cyp17a1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Cyp19a1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Hsd3b1	IEA	color key
Biological Process	GO:0006694	steroid biosynthetic process	Hsd17b1	IEA	color key
Biological Process	GO:0006694	steroid biosynthetic process	Hsd3b6	IEA	color key
Biological Process	GO:0006694	steroid biosynthetic process	Hsd17b2	IEA	color key
Biological Process	GO:0006694	steroid biosynthetic process	Hsd17b7	IEA	color key
Biological Process	GO:0006694	steroid biosynthetic process	Hsd3b1	IEA	color key
Biological Process	GO:0008202	steroid metabolic process	Cyp11a1	IEA	color key
Biological Process	GO:0006810	transport	Fdx1	IEA	color key