MGI MouseCyc GO annotations for PWY3DJ-35583

MGI MouseCyc GO annotations for PWY3DJ-35583: biosynthesis of prostaglandins

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY3DJ-35583.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Molecular Function	GO:0016209	antioxidant activity	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Molecular Function	GO:0005488	binding	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Molecular Function	GO:0003824	catalytic activity	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Molecular Function	GO:0009055	electron carrier activity	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Molecular Function	GO:0030528	transcription regulator activity	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Molecular Function	GO:0005215	transporter activity	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Cellular Component	GO:0005623	cell	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Cellular Component	GO:0044464	cell part	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Cellular Component	GO:0031975	envelope	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Cellular Component	GO:0005576	extracellular region	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Cellular Component	GO:0031974	membrane-enclosed lumen	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Cellular Component	GO:0043226	organelle	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Cellular Component	GO:0044422	organelle part	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0065007	biological regulation	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0009987	cellular process	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0032502	developmental process	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0051234	establishment of localization	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0040007	growth	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0051179	localization	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0008152	metabolic process	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0032501	multicellular organismal process	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0048519	negative regulation of biological process	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0050789	regulation of biological process	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0050896	response to stimulus	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1
Biological Process	GO:0048511	rhythmic process	Akr1c6	Hpgd	Ptgds	Ptgds2	Ptges	Ptges2	Ptges3	Ptgis	Ptgs1	Ptgs2	Tbxas1

Full set of annotations for PWY3DJ-35583

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity	Hpgd	IDA	color key
Molecular Function	GO:0005488	binding	Hpgd	IEA	color key
Molecular Function	GO:0005488	binding	Ptgds	IEA	color key
Molecular Function	GO:0003824	catalytic activity	Hpgd	IEA	color key
Molecular Function	GO:0003677	DNA binding	Ptges2	IDA	color key
Molecular Function	GO:0009055	electron carrier activity	Ptgis	IEA	color key
Molecular Function	GO:0009055	electron carrier activity	Ptges2	IEA	color key
Molecular Function	GO:0009055	electron carrier activity	Tbxas1	IEA	color key
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase activity	Akr1c6	IDA	color key
Molecular Function	GO:0004364	glutathione transferase activity	Ptgds2	ISO	color key
Molecular Function	GO:0020037	heme binding	Ptgis	IEA	color key
Molecular Function	GO:0020037	heme binding	Ptgs1	IEA	color key
Molecular Function	GO:0020037	heme binding	Ptgs2	IEA	color key
Molecular Function	GO:0020037	heme binding	Tbxas1	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Ptgis	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Ptgs1	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Ptgs2	IEA	color key
Molecular Function	GO:0005506	iron ion binding	Tbxas1	IEA	color key
Molecular Function	GO:0016853	isomerase activity	Ptgis	IEA	color key
Molecular Function	GO:0016853	isomerase activity	Ptgds2	IEA	color key
Molecular Function	GO:0016853	isomerase activity	Ptges2	IEA	color key
Molecular Function	GO:0016853	isomerase activity	Ptges	IEA	color key
Molecular Function	GO:0016853	isomerase activity	Ptges3	IEA	color key
Molecular Function	GO:0016853	isomerase activity	Tbxas1	IEA	color key
Molecular Function	GO:0016853	isomerase activity	Ptgds	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Ptgis	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Ptgs1	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Ptgs2	IEA	color key
Molecular Function	GO:0046872	metal ion binding	Tbxas1	IEA	color key
Molecular Function	GO:0003674	molecular_function	Ptges3	ND	color key
Molecular Function	GO:0004497	monooxygenase activity	Ptgis	IEA	color key
Molecular Function	GO:0004497	monooxygenase activity	Tbxas1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Hpgd	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Akr1c6	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Ptgs1	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Ptgs2	IEA	color key
Molecular Function	GO:0016491	oxidoreductase activity	Tbxas1	IEA	color key
Molecular Function	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Tbxas1	IEA	color key
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Ptgs1	IEA	color key
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Ptgs2	IEA	color key
Molecular Function	GO:0004601	peroxidase activity	Ptgs1	IEA	color key
Molecular Function	GO:0004601	peroxidase activity	Ptgs2	IEA	color key
Molecular Function	GO:0004667	prostaglandin-D synthase activity	Ptgds2	IDA	color key
Molecular Function	GO:0004667	prostaglandin-D synthase activity	Ptges	TAS	color key
Molecular Function	GO:0004667	prostaglandin-D synthase activity	Ptgds	IEA	color key
Molecular Function	GO:0050220	prostaglandin-E synthase activity	Ptges2	IEA	color key
Molecular Function	GO:0050220	prostaglandin-E synthase activity	Ptges	IEA	color key
Molecular Function	GO:0050220	prostaglandin-E synthase activity	Ptges3	IEA	color key
Molecular Function	GO:0004666	prostaglandin-endoperoxide synthase activity	Ptgs1	IEA	color key
Molecular Function	GO:0004666	prostaglandin-endoperoxide synthase activity	Ptgs2	IEA	color key
Molecular Function	GO:0008116	prostaglandin-I synthase activity	Ptgis	IEA	color key
Molecular Function	GO:0015035	protein disulfide oxidoreductase activity	Ptges2	IEA	color key
Molecular Function	GO:0004796	thromboxane-A synthase activity	Tbxas1	IMP	color key
Molecular Function	GO:0016563	transcription activator activity	Ptges2	IDA	color key
Molecular Function	GO:0005215	transporter activity	Ptgds	IEA	color key
Cellular Component	GO:0005575	cellular_component	Ptgds2	ND	color key
Cellular Component	GO:0005575	cellular_component	Ptges3	ND	color key
Cellular Component	GO:0005575	cellular_component	Akr1c6	ND	color key
Cellular Component	GO:0005737	cytoplasm	Hpgd	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Ptgds2	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Ptges2	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Ptges	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Ptges3	IEA	color key
Cellular Component	GO:0005737	cytoplasm	Ptgs1	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Ptgs2	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Ptgds	IEA	color key
Cellular Component	GO:0005829	cytosol	Ptges2	IDA	color key
Cellular Component	GO:0005783	endoplasmic reticulum	Ptgis	IEA	color key
Cellular Component	GO:0005783	endoplasmic reticulum	Ptgs1	IEA	color key
Cellular Component	GO:0005783	endoplasmic reticulum	Ptgs2	IEA	color key
Cellular Component	GO:0005783	endoplasmic reticulum	Ptgds	IEA	color key
Cellular Component	GO:0005576	extracellular region	Ptgds	IDA	color key
Cellular Component	GO:0005794	Golgi apparatus	Ptges2	IEA	color key
Cellular Component	GO:0005794	Golgi apparatus	Ptgds	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Ptgis	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Ptges2	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Ptges	IEA	color key
Cellular Component	GO:0016021	integral to membrane	Tbxas1	IEA	color key
Cellular Component	GO:0016020	membrane	Ptgis	IEA	color key
Cellular Component	GO:0016020	membrane	Ptges2	IEA	color key
Cellular Component	GO:0016020	membrane	Ptges	IEA	color key
Cellular Component	GO:0016020	membrane	Ptgs1	IEA	color key
Cellular Component	GO:0016020	membrane	Ptgs2	IEA	color key
Cellular Component	GO:0016020	membrane	Tbxas1	IEA	color key
Cellular Component	GO:0016020	membrane	Ptgds	IEA	color key
Cellular Component	GO:0005792	microsome	Ptges	IDA	color key
Cellular Component	GO:0005792	microsome	Ptgs1	IDA	color key
Cellular Component	GO:0005792	microsome	Ptgs2	IEA	color key
Cellular Component	GO:0005792	microsome	Tbxas1	IDA	color key
Cellular Component	GO:0005641	nuclear envelope lumen	Ptges	IDA	color key
Cellular Component	GO:0005634	nucleus	Ptges2	IDA	color key
Cellular Component	GO:0005634	nucleus	Ptgds	IEA	color key
Biological Process	GO:0042640	anagen	Ptgs2	IMP	color key
Biological Process	GO:0008150	biological_process	Ptges3	ND	color key
Biological Process	GO:0030282	bone mineralization	Ptgs2	ISO	color key
Biological Process	GO:0045454	cell redox homeostasis	Ptges2	IEA	color key
Biological Process	GO:0006633	fatty acid biosynthetic process	Ptgis	IEA	color key
Biological Process	GO:0006633	fatty acid biosynthetic process	Ptgds2	IEA	color key
Biological Process	GO:0006633	fatty acid biosynthetic process	Ptges2	IEA	color key
Biological Process	GO:0006633	fatty acid biosynthetic process	Ptges3	IEA	color key
Biological Process	GO:0006633	fatty acid biosynthetic process	Ptgs1	IEA	color key
Biological Process	GO:0006633	fatty acid biosynthetic process	Ptgs2	IEA	color key
Biological Process	GO:0006633	fatty acid biosynthetic process	Tbxas1	IEA	color key
Biological Process	GO:0006633	fatty acid biosynthetic process	Ptgds	IEA	color key
Biological Process	GO:0006631	fatty acid metabolic process	Hpgd	IEA	color key
Biological Process	GO:0030216	keratinocyte differentiation	Ptgs1	NAS	color key
Biological Process	GO:0030216	keratinocyte differentiation	Ptgs2	NAS	color key
Biological Process	GO:0008610	lipid biosynthetic process	Ptgis	IEA	color key
Biological Process	GO:0008610	lipid biosynthetic process	Ptgds2	IEA	color key
Biological Process	GO:0008610	lipid biosynthetic process	Ptges2	IEA	color key
Biological Process	GO:0008610	lipid biosynthetic process	Ptges3	IEA	color key
Biological Process	GO:0008610	lipid biosynthetic process	Akr1c6	IEA	color key
Biological Process	GO:0008610	lipid biosynthetic process	Ptgs1	IEA	color key
Biological Process	GO:0008610	lipid biosynthetic process	Ptgs2	IEA	color key
Biological Process	GO:0008610	lipid biosynthetic process	Tbxas1	IEA	color key
Biological Process	GO:0008610	lipid biosynthetic process	Ptgds	IEA	color key
Biological Process	GO:0006629	lipid metabolic process	Hpgd	IEA	color key
Biological Process	GO:0006629	lipid metabolic process	Ptgds	IEA	color key
Biological Process	GO:0008152	metabolic process	Hpgd	IEA	color key
Biological Process	GO:0008285	negative regulation of cell proliferation	Ptges	IGI	color key
Biological Process	GO:0055114	oxidation reduction	Hpgd	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Akr1c6	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Ptgs1	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Ptgs2	IEA	color key
Biological Process	GO:0055114	oxidation reduction	Tbxas1	IEA	color key
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptgis	IEA	color key
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptgds2	IEA	color key
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptges2	IEA	color key
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptges3	IEA	color key
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptgs1	IMP	color key
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptgs2	IEA	color key
Biological Process	GO:0001516	prostaglandin biosynthetic process	Tbxas1	IEA	color key
Biological Process	GO:0001516	prostaglandin biosynthetic process	Ptgds	IEA	color key
Biological Process	GO:0006693	prostaglandin metabolic process	Hpgd	IEA	color key
Biological Process	GO:0006693	prostaglandin metabolic process	Ptgds2	IDA	color key
Biological Process	GO:0006693	prostaglandin metabolic process	Ptges	IDA	color key
Biological Process	GO:0006693	prostaglandin metabolic process	Ptgs1	IMP	color key
Biological Process	GO:0008217	regulation of blood pressure	Ptgs1	IMP	color key
Biological Process	GO:0008217	regulation of blood pressure	Ptgs2	IMP	color key
Biological Process	GO:0042127	regulation of cell proliferation	Ptgs1	IGI	color key
Biological Process	GO:0042127	regulation of cell proliferation	Ptgs2	IGI	color key
Biological Process	GO:0045187	regulation of circadian sleep/wake cycle, sleep	Ptgds	IDA	color key
Biological Process	GO:0045449	regulation of transcription	Ptges2	IDA	color key
Biological Process	GO:0006979	response to oxidative stress	Ptgs1	IEA	color key
Biological Process	GO:0006979	response to oxidative stress	Ptgs2	IEA	color key
Biological Process	GO:0046903	secretion	Ptges2	IDA	color key
Biological Process	GO:0006694	steroid biosynthetic process	Akr1c6	IEA	color key
Biological Process	GO:0008202	steroid metabolic process	Akr1c6	IDA	color key
Biological Process	GO:0006810	transport	Ptgds	IEA	color key