MGI MouseCyc experimental GO annotations for P121-PWY

MGI MouseCyc experimental GO annotations for P121-PWY: salvage pathways of purine nucleosides

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for P121-PWY.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Molecular Function	GO:0005488	binding	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Molecular Function	GO:0003824	catalytic activity	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Cellular Component	GO:0005623	cell	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Cellular Component	GO:0044464	cell part	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Cellular Component	GO:0043226	organelle	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0065007	biological regulation	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0001906	cell killing	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0009987	cellular process	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0032502	developmental process	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0051234	establishment of localization	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0002376	immune system process	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0051179	localization	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0040011	locomotion	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0008152	metabolic process	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0051704	multi-organism process	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0032501	multicellular organismal process	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0048519	negative regulation of biological process	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0048518	positive regulation of biological process	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0050789	regulation of biological process	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0000003	reproduction	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0022414	reproductive process	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2
Biological Process	GO:0050896	response to stimulus	Ada	Adad1	Adad2	Adarb1	Adsl	Adss	Adssl1	Aprt	Gda	Hprt1	Impdh1	Impdh2	Pnp1	Pnp2

Full set of annotations for P121-PWY

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0002055	adenine binding	Aprt	IDA	color key
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IDA	color key
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IGI	color key
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IMP	color key
Molecular Function	GO:0004000	adenosine deaminase activity	Ada	IDA	color key
Molecular Function	GO:0004000	adenosine deaminase activity	Ada	IMP	color key
Molecular Function	GO:0004019	adenylosuccinate synthase activity	Adssl1	IDA	color key
Molecular Function	GO:0004019	adenylosuccinate synthase activity	Adss	IDA	color key
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	Hprt1	IDA	color key
Molecular Function	GO:0004422	hypoxanthine phosphoribosyltransferase activity	Hprt1	IMP	color key
Molecular Function	GO:0042802	identical protein binding	Hprt1	IPI	color key
Molecular Function	GO:0003938	IMP dehydrogenase activity	Impdh2	IDA	color key
Molecular Function	GO:0003938	IMP dehydrogenase activity	Impdh1	IDA	color key
Molecular Function	GO:0005515	protein binding	Adssl1	IPI	color key
Molecular Function	GO:0004731	purine-nucleoside phosphorylase activity	Pnp1	IDA	color key
Molecular Function	GO:0004731	purine-nucleoside phosphorylase activity	Pnp1	IMP	color key
Molecular Function	GO:0003723	RNA binding	Adad1	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Ada	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Adssl1	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Hprt1	IDA	color key
Cellular Component	GO:0005829	cytosol	Pnp1	IDA	color key
Cellular Component	GO:0005634	nucleus	Adad1	IDA	color key
Biological Process	GO:0046083	adenine metabolic process	Aprt	IGI	color key
Biological Process	GO:0046083	adenine metabolic process	Aprt	IMP	color key
Biological Process	GO:0046083	adenine metabolic process	Hprt1	IGI	color key
Biological Process	GO:0046083	adenine metabolic process	Hprt1	IMP	color key
Biological Process	GO:0006168	adenine salvage	Aprt	IMP	color key
Biological Process	GO:0006168	adenine salvage	Hprt1	IMP	color key
Biological Process	GO:0006154	adenosine catabolic process	Ada	IDA	color key
Biological Process	GO:0006154	adenosine catabolic process	Ada	IMP	color key
Biological Process	GO:0048286	alveolus development	Ada	IMP	color key
Biological Process	GO:0006167	AMP biosynthetic process	Adss	IDA	color key
Biological Process	GO:0007610	behavior	Hprt1	IMP	color key
Biological Process	GO:0021954	central nervous system neuron development	Hprt1	IMP	color key
Biological Process	GO:0021895	cerebral cortex neuron differentiation	Hprt1	IMP	color key
Biological Process	GO:0019835	cytolysis	Hprt1	IMP	color key
Biological Process	GO:0046061	dATP catabolic process	Ada	IDA	color key
Biological Process	GO:0046061	dATP catabolic process	Ada	IMP	color key
Biological Process	GO:0048813	dendrite morphogenesis	Hprt1	IMP	color key
Biological Process	GO:0006157	deoxyadenosine catabolic process	Ada	IDA	color key
Biological Process	GO:0006157	deoxyadenosine catabolic process	Ada	IMP	color key
Biological Process	GO:0006161	deoxyguanosine catabolic process	Pnp1	IMP	color key
Biological Process	GO:0006149	deoxyinosine catabolic process	Pnp1	IMP	color key
Biological Process	GO:0046070	dGTP metabolic process	Pnp1	IMP	color key
Biological Process	GO:0042417	dopamine metabolic process	Hprt1	IMP	color key
Biological Process	GO:0048566	embryonic gut development	Ada	IMP	color key
Biological Process	GO:0002314	germinal center B cell differentiation	Ada	IMP	color key
Biological Process	GO:0007625	grooming behavior	Aprt	IGI	color key
Biological Process	GO:0007625	grooming behavior	Hprt1	IGI	color key
Biological Process	GO:0006183	GTP biosynthetic process	Pnp1	IMP	color key
Biological Process	GO:0006178	guanine salvage	Hprt1	IMP	color key
Biological Process	GO:0046115	guanosine catabolic process	Pnp1	IMP	color key
Biological Process	GO:0046101	hypoxanthine biosynthetic process	Ada	IMP	color key
Biological Process	GO:0046100	hypoxanthine metabolic process	Hprt1	IMP	color key
Biological Process	GO:0001701	in utero embryonic development	Ada	IMP	color key
Biological Process	GO:0046103	inosine biosynthetic process	Ada	IDA	color key
Biological Process	GO:0046103	inosine biosynthetic process	Ada	IMP	color key
Biological Process	GO:0006148	inosine catabolic process	Pnp1	IMP	color key
Biological Process	GO:0001889	liver development	Ada	IMP	color key
Biological Process	GO:0030324	lung development	Ada	IMP	color key
Biological Process	GO:0046651	lymphocyte proliferation	Impdh2	IMP	color key
Biological Process	GO:0046651	lymphocyte proliferation	Hprt1	IMP	color key
Biological Process	GO:0046651	lymphocyte proliferation	Impdh1	IMP	color key
Biological Process	GO:0043066	negative regulation of apoptosis	Ada	IMP	color key
Biological Process	GO:0043066	negative regulation of apoptosis	Pnp1	IMP	color key
Biological Process	GO:0050728	negative regulation of inflammatory response	Ada	IGI	color key
Biological Process	GO:0050728	negative regulation of inflammatory response	Ada	IMP	color key
Biological Process	GO:0002686	negative regulation of leukocyte migration	Ada	IGI	color key
Biological Process	GO:0002686	negative regulation of leukocyte migration	Ada	IMP	color key
Biological Process	GO:0002906	negative regulation of mature B cell apoptosis	Ada	IMP	color key
Biological Process	GO:0070256	negative regulation of mucus secretion	Ada	IGI	color key
Biological Process	GO:0070256	negative regulation of mucus secretion	Ada	IMP	color key
Biological Process	GO:0060407	negative regulation of penile erection	Ada	IMP	color key
Biological Process	GO:0070244	negative regulation of thymocyte apoptosis	Ada	IMP	color key
Biological Process	GO:0048541	Peyer's patch development	Ada	IMP	color key
Biological Process	GO:0001890	placenta development	Ada	IMP	color key
Biological Process	GO:0046638	positive regulation of alpha-beta T cell differentiation	Ada	IMP	color key
Biological Process	GO:0046638	positive regulation of alpha-beta T cell differentiation	Pnp1	IMP	color key
Biological Process	GO:0045579	positive regulation of B cell differentiation	Pnp1	IMP	color key
Biological Process	GO:0030890	positive regulation of B cell proliferation	Ada	IMP	color key
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	Ada	IMP	color key
Biological Process	GO:0045739	positive regulation of DNA repair	Pnp1	IMP	color key
Biological Process	GO:0045964	positive regulation of dopamine metabolic process	Hprt1	IMP	color key
Biological Process	GO:0002636	positive regulation of germinal center formation	Ada	IMP	color key
Biological Process	GO:0010460	positive regulation of heart rate	Ada	IMP	color key
Biological Process	GO:0045987	positive regulation of smooth muscle contraction	Ada	IMP	color key
Biological Process	GO:0050870	positive regulation of T cell activation	Ada	IMP	color key
Biological Process	GO:0045582	positive regulation of T cell differentiation	Ada	IMP	color key
Biological Process	GO:0033089	positive regulation of T cell differentiation in the thymus	Ada	IMP	color key
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	Pnp1	IMP	color key
Biological Process	GO:0042102	positive regulation of T cell proliferation	Pnp1	IMP	color key
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	Ada	IMP	color key
Biological Process	GO:0042278	purine nucleoside metabolic process	Pnp1	IDA	color key
Biological Process	GO:0042278	purine nucleoside metabolic process	Pnp1	IMP	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Impdh2	IMP	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Adss	IDA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Hprt1	IMP	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Impdh1	IMP	color key
Biological Process	GO:0006163	purine nucleotide metabolic process	Adssl1	IDA	color key
Biological Process	GO:0006166	purine ribonucleoside salvage	Aprt	IGI	color key
Biological Process	GO:0006166	purine ribonucleoside salvage	Aprt	IMP	color key
Biological Process	GO:0006166	purine ribonucleoside salvage	Hprt1	IGI	color key
Biological Process	GO:0006166	purine ribonucleoside salvage	Hprt1	IMP	color key
Biological Process	GO:0045580	regulation of T cell differentiation	Ada	IMP	color key
Biological Process	GO:0001975	response to amphetamine	Hprt1	IMP	color key
Biological Process	GO:0010332	response to gamma radiation	Pnp1	IMP	color key
Biological Process	GO:0007286	spermatid development	Adad1	IMP	color key
Biological Process	GO:0021756	striatum development	Hprt1	IMP	color key
Biological Process	GO:0001829	trophectodermal cell differentiation	Ada	IMP	color key
Biological Process	GO:0034418	urate biosynthetic process	Pnp1	IMP	color key
Biological Process	GO:0046111	xanthine biosynthetic process	Ada	IMP	color key