MGI MouseCyc experimental GO annotations for PRPP-PWY

MGI MouseCyc experimental GO annotations for PRPP-PWY: superpathway of histidine, purine and pyrimidine biosynthesis

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PRPP-PWY.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Molecular Function	GO:0005488	binding	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Molecular Function	GO:0003824	catalytic activity	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Molecular Function	GO:0060089	molecular transducer activity	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Cellular Component	GO:0005623	cell	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Cellular Component	GO:0044464	cell part	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Cellular Component	GO:0031975	envelope	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Cellular Component	GO:0043226	organelle	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Cellular Component	GO:0044422	organelle part	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0065007	biological regulation	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0009987	cellular process	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0032502	developmental process	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0002376	immune system process	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0008152	metabolic process	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0032501	multicellular organismal process	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0048519	negative regulation of biological process	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0048518	positive regulation of biological process	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0050789	regulation of biological process	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0000003	reproduction	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0022414	reproductive process	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps
Biological Process	GO:0050896	response to stimulus	1190002A17Rik	AU021838	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Cad	Cmpk1	Cps1	Ctps	Ctps2	Dhodh	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mipol1	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Prps1	Prps1l1	Prps2	Prpsap1	Prpsap2	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9	Umps

Full set of annotations for PRPP-PWY

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0004017	adenylate kinase activity	Ak1	IDA	color key
Molecular Function	GO:0004019	adenylosuccinate synthase activity	Adssl1	IDA	color key
Molecular Function	GO:0004019	adenylosuccinate synthase activity	Adss	IDA	color key
Molecular Function	GO:0004086	carbamoyl-phosphate synthase activity	Cps1	IMP	color key
Molecular Function	GO:0004385	guanylate kinase activity	Guk1	IDA	color key
Molecular Function	GO:0003938	IMP dehydrogenase activity	Impdh2	IDA	color key
Molecular Function	GO:0003938	IMP dehydrogenase activity	Impdh1	IDA	color key
Molecular Function	GO:0004904	interferon receptor activity	Ifnar1	IMP	color key
Molecular Function	GO:0005515	protein binding	Ifnar1	IPI	color key
Molecular Function	GO:0005515	protein binding	Adssl1	IPI	color key
Molecular Function	GO:0005515	protein binding	Nme2	IPI	color key
Molecular Function	GO:0005515	protein binding	Rrm1	IPI	color key
Molecular Function	GO:0005515	protein binding	Rrm2	IPI	color key
Molecular Function	GO:0017076	purine nucleotide binding	Rrm1	IDA	color key
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity	Rrm2b	IDA	color key
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity	Rrm1	IDA	color key
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity	Rrm1	IPI	color key
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity	Rrm2	IDA	color key
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity	Rrm2	IMP	color key
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity	Rrm2	IPI	color key
Cellular Component	GO:0005737	cytoplasm	Adssl1	IDA	color key
Cellular Component	GO:0005737	cytoplasm	Ak1	IDA	color key
Cellular Component	GO:0005622	intracellular	Cps1	IDA	color key
Cellular Component	GO:0005792	microsome	Nme1	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Ak2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Ak3	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Dhodh	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Nme4	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Ak1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Ak2	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Ak3l1	IDA	color key
Cellular Component	GO:0005739	mitochondrion	Nme2	IDA	color key
Cellular Component	GO:0005886	plasma membrane	Mpp5	IDA	color key
Cellular Component	GO:0005886	plasma membrane	Ak1	IDA	color key
Cellular Component	GO:0005625	soluble fraction	Nme1	IDA	color key
Biological Process	GO:0006167	AMP biosynthetic process	Adss	IDA	color key
Biological Process	GO:0006916	anti-apoptosis	Nme5	IDA	color key
Biological Process	GO:0007050	cell cycle arrest	Ak1	IDA	color key
Biological Process	GO:0009200	deoxyribonucleoside triphosphate metabolic process	Rrm2b	IMP	color key
Biological Process	GO:0009263	deoxyribonucleotide biosynthetic process	Rrm2b	IDA	color key
Biological Process	GO:0009263	deoxyribonucleotide biosynthetic process	Rrm1	IDA	color key
Biological Process	GO:0009263	deoxyribonucleotide biosynthetic process	Rrm2	IDA	color key
Biological Process	GO:0009263	deoxyribonucleotide biosynthetic process	Rrm2	IMP	color key
Biological Process	GO:0009263	deoxyribonucleotide biosynthetic process	Rrm2	IPI	color key
Biological Process	GO:0009262	deoxyribonucleotide metabolic process	Rrm2	IDA	color key
Biological Process	GO:0006281	DNA repair	Rrm2b	IMP	color key
Biological Process	GO:0006917	induction of apoptosis	Rrm2b	IMP	color key
Biological Process	GO:0001822	kidney development	Rrm2b	IMP	color key
Biological Process	GO:0007595	lactation	Nme1	IMP	color key
Biological Process	GO:0046651	lymphocyte proliferation	Impdh2	IMP	color key
Biological Process	GO:0046651	lymphocyte proliferation	Impdh1	IMP	color key
Biological Process	GO:0030879	mammary gland development	Nme1	IMP	color key
Biological Process	GO:0006264	mitochondrial DNA replication	Rrm2b	IMP	color key
Biological Process	GO:0032729	positive regulation of interferon-gamma production	Ifnar1	IGI	color key
Biological Process	GO:0051259	protein oligomerization	Rrm1	IPI	color key
Biological Process	GO:0051259	protein oligomerization	Rrm2	IPI	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Impdh2	IMP	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Adss	IDA	color key
Biological Process	GO:0006164	purine nucleotide biosynthetic process	Impdh1	IMP	color key
Biological Process	GO:0006163	purine nucleotide metabolic process	Adssl1	IDA	color key
Biological Process	GO:0003014	renal system process	Rrm2b	IMP	color key
Biological Process	GO:0006979	response to oxidative stress	Rrm2b	IMP	color key
Biological Process	GO:0007286	spermatid development	Nme5	IDA	color key
Biological Process	GO:0042110	T cell activation	Ifnar1	IGI	color key
Biological Process	GO:0045351	type I interferon biosynthetic process	Ifnar1	IMP	color key