MGI MouseCyc experimental GO annotations for PWY66-221

MGI MouseCyc experimental GO annotations for PWY66-221: nicotine degradation III

Roles of genes might be detected in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";
Black arrows indicate "regulates";
Green arrows indicate "positively_regulates";
Red arrows indicate "negatively_regulates"

Compare annotations to GO categories for PWY66-221.

Entry indicates that gene is in this pathway.
Colored entries indicate GO annotation.

Category	ID	Term	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Molecular Function	GO:0003824	catalytic activity	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Cellular Component	GO:0005623	cell	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Cellular Component	GO:0044464	cell part	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Cellular Component	GO:0031975	envelope	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Cellular Component	GO:0043226	organelle	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Cellular Component	GO:0044422	organelle part	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Biological Process	GO:0065007	biological regulation	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Biological Process	GO:0009987	cellular process	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Biological Process	GO:0032502	developmental process	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Biological Process	GO:0008152	metabolic process	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Biological Process	GO:0032501	multicellular organismal process	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Biological Process	GO:0050789	regulation of biological process	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5
Biological Process	GO:0050896	response to stimulus	Aox1	Cyp19a1	Cyp1a1	Cyp1a2	Cyp1b1	Cyp2a12	Cyp2a4	Cyp2a5	Cyp2b10	Cyp2b19	Cyp2b9	Cyp2c29	Cyp2c37	Cyp2c38	Cyp2c39	Cyp2c40	Cyp2c44	Cyp2c65	Cyp2c70	Cyp2d10	Cyp2d11	Cyp2d26	Cyp2d9	Cyp2e1	Cyp2s1	Cyp3a11	Cyp3a13	Cyp3a16	Cyp3a25	Cyp3a41a	Ugt1a1	Ugt1a6a	Ugt1a7c	Ugt2b1	Ugt2b35	Ugt2b5

Full set of annotations for PWY66-221

Category	ID	Term	Mouse gene	Evidence	Color Key
Molecular Function	GO:0004031	aldehyde oxidase activity	Aox1	IDA	color key
Molecular Function	GO:0015020	glucuronosyltransferase activity	Ugt1a6a	IDA	color key
Molecular Function	GO:0004497	monooxygenase activity	Cyp1a1	IDA	color key
Molecular Function	GO:0004497	monooxygenase activity	Cyp2e1	IDA	color key
Molecular Function	GO:0004497	monooxygenase activity	Cyp3a11	IDA	color key
Molecular Function	GO:0050381	unspecific monooxygenase activity	Cyp19a1	IDA	color key
Molecular Function	GO:0050381	unspecific monooxygenase activity	Cyp1a1	IDA	color key
Molecular Function	GO:0050381	unspecific monooxygenase activity	Cyp1a2	IDA	color key
Cellular Component	GO:0005783	endoplasmic reticulum	Cyp2e1	IDA	color key
Cellular Component	GO:0005887	integral to plasma membrane	Ugt1a1	IDA	color key
Cellular Component	GO:0005792	microsome	Cyp1a1	IDA	color key
Cellular Component	GO:0005792	microsome	Cyp1a2	IDA	color key
Cellular Component	GO:0005792	microsome	Cyp1b1	IDA	color key
Cellular Component	GO:0005792	microsome	Cyp2a4	IDA	color key
Cellular Component	GO:0005792	microsome	Cyp2d9	IDA	color key
Cellular Component	GO:0005792	microsome	Cyp2e1	IDA	color key
Cellular Component	GO:0005792	microsome	Cyp3a11	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Ugt1a6a	IDA	color key
Cellular Component	GO:0005743	mitochondrial inner membrane	Ugt2b5	IDA	color key
Biological Process	GO:0009308	cellular amine metabolic process	Cyp1a1	IMP	color key
Biological Process	GO:0006725	cellular aromatic compound metabolic process	Cyp1a2	IMP	color key
Biological Process	GO:0045333	cellular respiration	Cyp1a2	IMP	color key
Biological Process	GO:0018894	dibenzo-p-dioxin metabolic process	Cyp1a2	IMP	color key
Biological Process	GO:0017144	drug metabolic process	Cyp1a2	IMP	color key
Biological Process	GO:0019585	glucuronate metabolic process	Ugt1a6a	IDA	color key
Biological Process	GO:0046483	heterocycle metabolic process	Cyp1a1	IMP	color key
Biological Process	GO:0050665	hydrogen peroxide biosynthetic process	Cyp1a1	IMP	color key
Biological Process	GO:0050665	hydrogen peroxide biosynthetic process	Cyp1a2	IMP	color key
Biological Process	GO:0030324	lung development	Cyp1a2	IMP	color key
Biological Process	GO:0006778	porphyrin metabolic process	Cyp1a2	IMP	color key
Biological Process	GO:0009791	post-embryonic development	Cyp1a2	IMP	color key
Biological Process	GO:0010468	regulation of gene expression	Cyp1a2	IMP	color key
Biological Process	GO:0009404	toxin metabolic process	Cyp1a1	IMP	color key
Biological Process	GO:0009404	toxin metabolic process	Cyp1a2	IMP	color key
Biological Process	GO:0009404	toxin metabolic process	Cyp1b1	IMP	color key